KEGG ORTHOLOGY: K05025

ORTHOLOGY: K05025

Entry

K05025                      KO

Symbol

CLIC5

Name

chloride intracellular channel protein 5

Disease

H00605

Deafness, autosomal recessive

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins
    K05025  CLIC5; chloride intracellular channel protein 5
   04040 Ion channels
    K05025  CLIC5; chloride intracellular channel protein 5
Cilium and associated proteins [BR:ko03037]
Other cilia and associated proteins
  Stereociliary proteins
   K05025  CLIC5; chloride intracellular channel protein 5
Ion channels [BR:ko04040]
Chloride channels
  Chloride channel, intracellular (CLIC)
   K05025  CLIC5; chloride intracellular channel protein 5

Other DBs

GO:

0005247

TC:	1.A.12.1.1 1.A.12.1.3

Genes

HSA:	53405(CLIC5)

PTR:	462739(CLIC5)

PPS:	100969744(CLIC5)

GGO:	101149402(CLIC5)

PON:	100453932(CLIC5)

PPYG:

129038790(CLIC5)

NLE:	100587743(CLIC5)

HMH:	116459751(CLIC5)

SSYN:

129473853(CLIC5)

MCC:	703565(CLIC5)

MCF:	102120108(CLIC5)

MTHB:

126953581

MNI:	105489525(CLIC5)

CSAB:

103221422(CLIC5)

CATY:

105590909(CLIC5)

PANU:

101006615(CLIC5)

TGE:	112622705(CLIC5)

MLEU:

105544367(CLIC5)

RRO:	104669544(CLIC5)

RBB:	108533432(CLIC5)

TFN:	117087305(CLIC5)

PTEH:

111543110(CLIC5)

CANG:

105524874(CLIC5)

CJC:	100407287(CLIC5)

SBQ:	101046473(CLIC5)

CIMI:

108286971(CLIC5)

ANAN:

105714694(CLIC5)

CSYR:

103259539(CLIC5)

MMUR:

105866836(CLIC5)

LCAT:

123632907(CLIC5)

PCOQ:

105826661(CLIC5)

OGA:	100962671(CLIC5)

MMU:	224796(Clic5)

MCAL:

110283957(Clic5)

MPAH:

110335861(Clic5)

RNO:	94272(Clic5)

MCOC:

116074524(Clic5)

ANU:	117722379(Clic5)

ASYL:

127692241(Clic5)

MUN:	110555960(Clic5)

CGE:	100756242(Clic5)

MAUA:

101823812(Clic5)

PROB:

127236547(Clic5)

PLEU:

114707841(Clic5)

MORG:

121450701(Clic5)

MFOT:

126486863

AAMP:

119823899(Clic5)

NGI:	103730757(Clic5)

HGL:	101722173(Clic5)

CPOC:

100733897(Clic5)

CCAN:

109699916

DORD:

105987821(Clic5)

DSP:	122101580(Clic5)

DMER:

138828013(Clic5)

PLOP:

125352522(Clic5)

NCAR:

124988513

MMMA:

107143967(Clic5)

ITI:	101974049(Clic5)

OCU:

100342637

OPI:	101526421(CLIC5)

OCZ:	121158626(CLIC5)

TUP:	102470825(CLIC5)

CFA:	481822(CLIC5)

CLUD:

112641679(CLIC5)

VVP:	112914044(CLIC5)

VLG:	121486222(CLIC5)

NPO:	129512965(CLIC5)

AML:	100470286(CLIC5)

UMR:	103664040(CLIC5)

UAH:	113261239(CLIC5)

UAR:	123795149(CLIC5)

ELK:

111147701

LLV:

125101947

MPUF:

101679906(CLIC5)

MNP:	132017998(CLIC5)

MLK:	131834050(CLIC5)

NVS:	122908826(CLIC5)

ORO:	101373467(CLIC5)

EJU:	114204457(CLIC5)

ZCA:	113926973(CLIC5)

MLX:	118001293(CLIC5)

NSU:	110582108(CLIC5)

LWW:

115944622

FCA:	101099207(CLIC5)

PYU:	121029533(CLIC5)

PCOO:

112861998(CLIC5)

PBG:	122489585(CLIC5)

PVIV:

125165927(CLIC5)

LRUF:

124528084

LGF:	123608455(CLIC5)

AJU:

106974002

PTG:	102972751(CLIC5)

PPAD:

109271696(CLIC5)

PUC:

125937891

PLEZ:

122219985(CLIC5)

HHV:	120231232(CLIC5)

BTA:	281696(CLIC5)

BOM:	102274960(CLIC5)

BIU:	109576983(CLIC5)

BBUB:

102407845(CLIC5)

BBIS:

105005185(CLIC5)

CHX:	102182080(CLIC5)

OAS:	101119340(CLIC5)

BTAX:

128055104(CLIC5)

CSUM:

138069406(CLIC5)

ODA:	120870056(CLIC5)

CCAD:

122429213(CLIC5)

MREE:

136151944(CLIC5)

OVR:	110137850(CLIC5)

MBEZ:

129543860(CLIC5)

SSC:	100154589(CLIC5)

CFR:	102518960(CLIC5)

CBAI:

105083834(CLIC5)

CDK:	105101199(CLIC5)

VPC:	102532003(CLIC5)

BACU:

103013699

BMUS:

118903774

LVE:	103072580(CLIC5)

OOR:	101275833(CLIC5)

LALB:

132527403(CLIC5)

GMF:	115860630(CLIC5)

DDP:	132431954 132431955(CLIC5)

DLE:	111178885(CLIC5)

PCAD:

102974082(CLIC5)

PSIU:

116761630(CLIC5)

PPHC:

136128853(CLIC5)

NASI:

112413943(CLIC5)

ECB:	100055661(CLIC5)

EPZ:	103565951(CLIC5)

EAI:	106828763(CLIC5)

MYB:	102257981(CLIC5)

MYD:	102751949(CLIC5)

MMYO:

118660146(CLIC5)

MLF:	102422017(CLIC5)

MDT:	132237270(CLIC5)

MYUM:

139012467(CLIC5)

PKL:	118705965(CLIC5)

EFUS:

103296612(CLIC5)

MNA:	107536850(CLIC5)

DRO:	112302169(CLIC5)

SHON:

118992320(CLIC5)

AJM:	119047189(CLIC5)

PDIC:

114494634(CLIC5)

PHAS:

123821533(CLIC5)

MMF:	118621960(CLIC5)

PPAM:

129067500(CLIC5)

HAI:	109382900(CLIC5)

RFQ:	117020153(CLIC5)

PALE:

102886305(CLIC5)

PGIG:

120595949(CLIC5)

PVP:	105288507(CLIC5)

RAY:	107504074(CLIC5)

MJV:	108409032(CLIC5)

TOD:	119252533(CLIC5)

SARA:

101538341(CLIC5)

SFUM:

130034537(CLIC5)

SETR:

125996572(CLIC5)

LAV:	100654739(CLIC5)

TMU:

101346146

ETF:	101651084(CLIC5)

DNM:	101434540(CLIC5)

MDO:	100014060(CLIC5)

GAS:	123246431(CLIC5)

SHR:	105750512(CLIC5)

AFZ:

127561811

PCW:	110213504(CLIC5)

TVP:	118856944(CLIC5)

PBRV:

138144530(CLIC5)

OAA:	100080546(CLIC5)

TACU:

119932352(CLIC5)

GGA:	422054(CLIC5)

PCOC:

116236339(CLIC5)

MGP:	100549817(CLIC5)

CJO:	107312459(CLIC5)

TPAI:

128085522(CLIC5)

LMUT:

125688839(CLIC5)

NMEL:

110395835(CLIC5)

APLA:

101790561(CLIC5)

ACYG:

106038196(CLIC5)

CATA:

118254710(CLIC5)

AFUL:

116487983(CLIC5)

TGU:	100229341(CLIC5)

LSR:	110468945(CLIC5)

SCAN:

103821126(CLIC5)

PMOA:

120496010(CLIC5)

OTC:	121347513(CLIC5)

PRUF:

121360866(CLIC5)

ATRC:

139599668(CLIC5)

GFR:

102043166

FAB:	101806479(CLIC5)

OMA:	130251086(CLIC5)

PHI:	102114618(CLIC5)

PMAJ:

107202307(CLIC5)

CCAE:

111927412(CLIC5)

CCW:	104685377(CLIC5)

CBRC:

103622825(CLIC5)

ACOE:

138108725(CLIC5)

ETL:	114058823(CLIC5)

ZAB:	102064252(CLIC5)

ZLE:	135445086(CLIC5)

ACHL:

103798937

SVG:	106851161(CLIC5)

MMEA:

130578985(CLIC5)

HRT:	120750076(CLIC5)

SATI:

136358725(CLIC5)

CCIC:

134042386(CLIC5)

FPG:	101922610(CLIC5)

FCH:	102052781(CLIC5)

CCRI:

104169381(CLIC5)

NNT:	104410226(CLIC5)

SHAB:

115609960(CLIC5)

ACUN:

113478352(CLIC5)

TALA:

104360480(CLIC5)

ACHC:

115351233(CLIC5)

HALD:

104325459(CLIC5)

HLE:	104842162(CLIC5)

AGEN:

126046557

HHAR:

128151916(CLIC5)

GCL:

127014698

CSTI:

104561090(CLIC5)

LDI:

104342120

MNB:	103777166(CLIC5)

DPUB:

104304543(CLIC5)

PPUS:

135176639(CLIC5)

AVIT:

104267833(CLIC5)

BRHI:

104496188(CLIC5)

EGZ:	104127000(CLIC5)

NNI:	104014668(CLIC5)

PCRI:

104034518

PCAO:

104051710(CLIC5)

PADL:

103913210(CLIC5)

AFOR:

103906909(CLIC5)

FGA:

104071394

CBOR:

142080070(CLIC5)

CBOY:

140649922(CLIC5)

MAME:

142407965(CLIC5)

CLV:	102094989(CLIC5)

CNIC:

135986524(CLIC5)

MUI:

104539922

PGUU:

104459374

PLET:

104626768(CLIC5)

EHS:

104508277

CUCA:

104057105(CLIC5)

TEO:	104376996(CLIC5)

BREG:

104633364(CLIC5)

OHA:	104339143(CLIC5)

ACAR:

104520466

CPEA:

104395206(CLIC5)

CVF:	104286824(CLIC5)

RTD:	128907443(CLIC5)

CRID:

134513628(CLIC5)

LMIC:

141741403(CLIC5)

AAM:	106495196(CLIC5)

AROW:

112962868(CLIC5)

NPD:	112947832(CLIC5)

DNE:	112979544(CLIC5)

SCAM:

104139686(CLIC5)

ASN:	102387193(CLIC5)

AMJ:	102561184(CLIC5)

CPOO:

109311480(CLIC5)

GGN:	109300284(CLIC5)

PSS:	102456374(CLIC5)

CIZ:	142011609(CLIC5)

CMY:	102944750(CLIC5)

CCAY:

125634654(CLIC5)

DCC:	119852675(CLIC5)

CPIC:

101936459(CLIC5)

TST:	117875375(CLIC5)

CABI:

116837552(CLIC5)

MRV:	120402317(CLIC5)

ACS:	100563513(clic5)

ASAO:

132781259(CLIC5)

PVT:	110083227(CLIC5)

SUND:

121930668(CLIC5)

PBI:

103058327

PMUR:

107284278(CLIC5)

CTIG:

120300434(CLIC5)

TSR:	106545872(CLIC5)

PGUT:

117671111(CLIC5)

PCAE:

139309051(CLIC5)

APRI:

131198708(CLIC5)

PTEX:

113440956(CLIC5)

NSS:	113422637(CLIC5)

VKO:	123017729(CLIC5)

PMUA:

114590468 114593478(CLIC5)

PRAF:

128409852(CLIC5)

ZVI:	118082592(CLIC5)

HCG:	128339727(CLIC5)

GJA:	107105577(CLIC4)

EMC:	129341555(CLIC5)

XLA:	108717222 380025(clic5.S)

XTR:	448566(clic5)

NPR:	108795531(CLIC5)

RTEM:

120936235(CLIC5)

ACAT:

141139284(CLIC5)

BBUF:

120997271(CLIC5)

BGAR:

122924215

DTC:	141098600(CLIC5)

PWL:	138296708(CLIC5)

MUO:	115467083(CLIC5)

GSH:	117357096(CLIC5)

DRE:	405833(clic5b) 492513(clic5a)

SRX:	107717236 107726746 107733467 107743284

SANH:

107653868 107678823 107693078 107697168

SGH:	107549663 107552039 107594079 107603103

CCAR:

109106869 109107857(clic5a) 109112862 109113630

CAUA:

113060827 113080868 113092562 113104870 113117813 113120486 113120539

CGIB:

127933459 127938993 127976156 127984399

PTET:

122325064(clic5b) 122361479(clic5a)

LROH:

127180208(clic5a) 127183298(clic5b)

GRF:	141283470(clic5b) 141295501(clic5a) 141295762

OMC:	131523071(clic5a) 131527769(clic5b)

PPRM:

120471094 120471182 120492120(clic5b)

RKG:	130088937(clic5a) 130103104(clic5b)

MAMB:

125262030 125268309(clic5a) 125278437(clic5b)

CIDE:

127498485 127502649

CERY:

137006764(clic5a) 137019177(clic5b)

MASI:

127409857 127410740 127415672

TROS:

130560561(clic5a) 130565494(clic5b)

TDW:	130434776(clic5b) 130437125(clic5a)

MANU:

129417536(clic5a) 129429772(clic5b)

PDAB:

135736214(clic5a) 135738327(clic5b)

IPU:	108258161(clic5b) 108270377(clic5a)

IFU:	128601354(clic5b) 128612865(clic5a)

PHYP:

113538787(clic5) 113545245

SMEO:

124377338(clic5b) 124389614(clic5a)

TFD:	113644881(clic5b) 113659676(clic5a)

TVC:	132843302(clic5b) 132852032(clic5a)

CGAR:

128514675(clic5b) 128535924(clic5a)

NGRA:

132882982(clic5b) 132893940(clic5a)

TRN:	134320063(clic5b) 134325005(clic5a)

AMEX:

103041670(clic5a) 103046322

CMAO:

118815547(clic5b) 118823967(clic5a)

EEE:	113572643(clic5) 113588872

CHAR:

105897798 105909474(clic5a)

SPIL:

134067457(clic5a) 134098032

ASAD:

121693571(clic5a) 121711932

TRU:	101070710 101072248

TFS:	130516567(clic5b) 130523167(clic5a)

TNG:	GSTEN00013474G001 GSTEN00018384G001

LCO:	104925341 104930002

NCC:	104958973 104962912

TBEN:

117498376(clic5b) 117499250

CGOB:

115003485 115019042(clic5)

PGEO:

117440289(clic5b) 117460425(clic5a)

GACU:

117554231(clic5b) 117562712

EMAC:

134860689(clic5a) 134877308(clic5b)

ELY:	117249815(clic5a) 117270441(clic5b)

EFO:	125884778(clic5a) 125897091(clic5b)

PLEP:

121955879(clic5b) 121962906(clic5a)

SLUC:

116041998(clic5b) 116044775(clic5a)

ECRA:

117939641(clic5a) 117961118(clic5b)

ESP:	116673960 116706663(clic5)

PFLV:

114550956 114572790(clic5)

GAT:	120808417(clic5b) 120820210(clic5a)

PPUG:

119194708(clic5b) 119200240(clic5a)

AFB:	129107204(clic5b) 129111709(clic5a)

CLUM:

117745764(clic5a)

PSWI:

130202512(clic5b) 130204491(clic5a)

CANA:

137785532(clic5b) 137793984

CVE:	137871266 137879008

MSAM:

119902014(clic5a) 119908798(clic5b)

SCHU:

122862823(clic5b) 122872214(clic5a)

CUD:	121506043(clic5a) 121521944(clic5b)

SPUL:

138584711(clic5b) 138603489(clic5a)

LMIX:

132959311(clic5a) 132985222(clic5b)

HTC:	141785910 141801807(clic5b)

ALAT:

119013103(clic5b) 119015482(clic5a)

ASTR:

137591460 137613200(clic5b)

MZE:	101475791(clic5) 101481750

ONL:	100691517 100700804

OAU:	116321796(clic5a) 116332265(clic5b)

OLA:	101162647 101168438

OML:	112157727(clic5b) 112159970(clic5a)

CSAI:

133425013(clic5a) 133464478(clic5b)

XMA:	102229179 102236394

XCO:	114140774 114158643

XHE:	116715590 116734654

PRET:

103457844 103476237

PFOR:

103141416 103148023

PLAI:

106948949 106964163

PMEI:

106914661 106927108(clic5)

GAF:	122825247(clic5b) 122827254(clic5a)

PPRL:

129368964(clic5b) 129379055(clic5a)

CVG:	107094130(clic5) 107097336

CTUL:

119784155(clic5b) 119789715(clic5a)

GMU:	124861902(clic5a) 124882294(clic5b)

NFU:	107378135 107381043

KMR:	108231874(clic5b) 108246484(clic5a)

ALIM:

106519107 106530951

NWH:	119418461(clic5b) 119428900

AOCE:

111562779 111573515(clic5b)

EJA:	138203600(clic5b) 138208500(clic5a)

BFRE:

138629235(clic5a) 138630106(clic5b)

MCEP:

124999418(clic5b) 125001108(clic5a)

CSEM:

103381038 103389681

POV:	109632556 109639756

SSEN:

122761504(clic5a) 122783637(clic5b)

SSOE:

131443937(clic5a) 131444027(clic5b)

HHIP:

117758156(clic5b) 117775465(clic5a)

HSP:	118099184(clic5b) 118103430(clic5a)

PPLT:

128431128(clic5a) 128459930(clic5b)

SMAU:

118290082(clic5b) 118309573(clic5a)

LCF:	108891870(clic5a) 108898079(clic5b)

SDU:	111222707 111240463

SLAL:

111646011 111672624

XGL:	120788573(clic5b) 120798022(clic5a)

HCQ:	109507236 109515033

SSCV:

125988661(clic5a) 125989899(clic5b)

SBIA:

133495633 133496951(clic5b)

PEE:	133410217(clic5a) 133416994(clic5b)

PTAO:

133468331(clic5b) 133488939(clic5a)

BPEC:

110153277 110173913

ENY:	140355319(clic5b) 140380779(clic5a)

MALB:

109955587 109962227

BSPL:

114850052(clic5b) 114851096 114851097

SJO:	128354152(clic5a) 128376764(clic5b)

SSCO:

133976247(clic5a) 133998076(clic5b)

TTY:	137169378(clic5b)

GMH:	115534394 115542911

SASA:

100196811(clic5) 106593848

STRU:

115162202 115206734

OTW:	112237991 112246845

OMY:	110505659(clic5a) 110510406

OGO:	123995484 124028063 124046554

ONE:	115116597 115138601(clic5)

OKI:	109885220 109904142

OKE:	118368198 118382193

OMM:	135525765(clic5a) 135558022

OCLA:

139383871 139407444

SALP:

111963370(clic5)

SNH:	120023726(clic5a)

SFON:

129813003(clic5a) 129825614

CCLU:

121544340(clic5a) 121548519

ELS:	105005605(clic5) 105017981

OEP:	134007771(clic5a) 134025089(clic5b)

SFM:	108921359 108929130

PKI:	111837936 111857989

AANG:

118229971

AROT:

135257694

CCOG:

133129546

LOC:	102695634(clic5)

PSPA:

121315625 121317430(clic5b)

ARUT:

117403253 117410696(clic5b)

PSEX:

120526315

LCM:	102350369(CLIC5)

CMK:

RTP:

CPLA:

HOC:

SCAU:

LERI:

HAKA:

PMRN:

LRJ:	133341831 133354507

BBEL:

ARUN:

AAMU:

PFLL:

HAMR:

PTRU:

ESN:

PVUL:

HASI:

HCRA:

MAEA:

OSN:

LJP:

ATEN:

HSY:

Reference

PMID:10793131

Authors

Berryman M, Bretscher A

Title

Identification of a novel member of the chloride intracellular channel gene family (CLIC5) that associates with the actin cytoskeleton of placental microvilli.

Journal

Mol Biol Cell 11:1509-21 (2000)
DOI:10.1091/mbc.11.5.1509

Sequence

[hsa:53405]

LinkDB

DBGET integrated database retrieval system