KEGG ORTHOLOGY: K05216

ORTHOLOGY: K05216

Entry

K05216                      KO

Symbol

P2RX2

Name

P2X purinoceptor 2

Pathway

map04020

Calcium signaling pathway

map04080

Neuroactive ligand-receptor interaction

map04082

Neuroactive ligand signaling

map04742

Taste transduction

Disease

H00604

Deafness, autosomal dominant

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K05216  P2RX2; P2X purinoceptor 2
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05216  P2RX2; P2X purinoceptor 2
   04082 Neuroactive ligand signaling
    K05216  P2RX2; P2X purinoceptor 2
09150 Organismal Systems
  09157 Sensory system
   04742 Taste transduction
    K05216  P2RX2; P2X purinoceptor 2
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K05216  P2RX2; P2X purinoceptor 2
Ion channels [BR:ko04040]
Ligand-gated channels
  ATP-gated cation channel (P2X)
   K05216  P2RX2; P2X purinoceptor 2

Other DBs

GO:	0001614 0004931

TC:

1.A.7.1.2

Genes

HSA:	22953(P2RX2)

PTR:	100615394(P2RX2)

GGO:	101124304(P2RX2)

PON:	100455448(P2RX2)

PPYG:

129010521(P2RX2)

NLE:	100586671(P2RX2)

HMH:	116477658(P2RX2)

SSYN:

129460368(P2RX2)

MCC:	693390(P2RX2)

MCF:	102121756(P2RX2)

MTHB:

126931682

MNI:	105490570(P2RX2)

CSAB:

103239451(P2RX2)

CATY:

105600723(P2RX2)

PANU:

101013744(P2RX2)

TGE:	112634976(P2RX2)

MLEU:

105541281(P2RX2)

RRO:	104674327(P2RX2)

RBB:	108544495(P2RX2)

TFN:	117089146(P2RX2)

PTEH:

111529821(P2RX2)

CANG:

105525640(P2RX2)

CJC:	100406252(P2RX2)

SBQ:	101028224(P2RX2)

CIMI:

108292639(P2RX2)

ANAN:

105709077(P2RX2)

CSYR:

103255391(P2RX2)

MMUR:

105861813 105861814

LCAT:

123625599(P2RX2)

PCOQ:

105820715(P2RX2)

OGA:	100946102(P2RX2)

MMU:	231602(P2rx2)

MCAL:

110294404(P2rx2)

MPAH:

110312899(P2rx2)

RNO:	114115(P2rx2)

MCOC:

116068123(P2rx2)

ANU:	117698148(P2rx2)

ASYL:

127672393(P2rx2)

MUN:	110553168(P2rx2)

CGE:	100770815(P2rx2)

MAUA:

101842393(P2rx2)

PROB:

127215916(P2rx2)

PLEU:

114682911(P2rx2)

MORG:

121446320(P2rx2)

MFOT:

126511666

AAMP:

119825287(P2rx2)

NGI:	103750602(P2rx2)

HGL:	101719917(P2rx2)

CPOC:

100135591(P2rx2)

CCAN:

109686266(P2rx2)

DSP:	122096677(P2rx2)

PLOP:

125347991(P2rx2)

NCAR:

124991035

ITI:	101956790(P2rx2)

OCU:

100356670

OPI:	101525302(P2RX2)

TUP:	102473926(P2RX2)

GVR:	103585289(P2RX2)

CFA:	448781(P2RX2)

CLUD:

112676381(P2RX2)

VVP:	112911612(P2RX2)

VLG:	121475344(P2RX2)

NPO:	129507521(P2RX2)

UMR:	103678891(P2RX2)

UAH:	113266840(P2RX2)

UAR:	123803880(P2RX2)

ELK:

111139780

LLV:

125082130

MPUF:

101672150(P2RX2)

MNP:	132023781(P2RX2)

MLK:	131811673(P2RX2)

NVS:	122901990(P2RX2)

ORO:	101370874(P2RX2)

EJU:	114202375(P2RX2)

ZCA:	113913178(P2RX2)

MLX:	118018306(P2RX2)

NSU:	110582303(P2RX2)

LWW:	102739226(P2RX2)

FCA:	751616(P2RX2)

PBG:	122470088(P2RX2)

PVIV:

125149117(P2RX2)

LRUF:

124527817

LGF:	123587789(P2RX2)

AJU:

106985892

PTG:	102963320(P2RX2)

PPAD:

109260676(P2RX2)

PUC:

125915023

PLEZ:

122203423(P2RX2)

HHV:	120224513(P2RX2)

BTA:	527499(P2RX2)

BOM:	102275962(P2RX2)

BIU:	109570897(P2RX2)

BBUB:

102404943(P2RX2)

BBIS:

104997606(P2RX2)

CHX:	102171362(P2RX2)

OAS:	101116428(P2RX2)

BTAX:

128062344(P2RX2)

CSUM:

138093769(P2RX2)

ODA:	120871536(P2RX2)

CCAD:

122419908(P2RX2)

MREE:

136145780(P2RX2)

OVR:	110145403(P2RX2)

MBEZ:

129542559(P2RX2)

SSC:	100736581(P2RX2)

CFR:	102509791(P2RX2)

CBAI:

105063749(P2RX2)

CDK:	105104095(P2RX2)

VPC:	102536188(P2RX2)

BACU:

102998993(P2RX2)

BMUS:

118879984(P2RX2)

LVE:	103075363(P2RX2)

OOR:	101280504(P2RX2)

LALB:

132532274(P2RX2)

DLE:	111186962(P2RX2)

PCAD:

102988237(P2RX2)

PSIU:

116739203(P2RX2)

NASI:

112396248(P2RX2)

ECB:	100061704(P2RX2)

EPZ:	103561639(P2RX2)

EAI:	106843862(P2RX2)

MYB:	102242465(P2RX2)

MYD:	102770010(P2RX2)

MMYO:

118653025(P2RX2)

MLF:	102441703(P2RX2)

MDT:	132221640(P2RX2)

MYUM:

138997606(P2RX2)

PKL:	118716865(P2RX2)

EFUS:

103300415(P2RX2)

MNA:	107529657(P2RX2)

DRO:	112310430(P2RX2)

SHON:

118990979(P2RX2)

AJM:	119060727(P2RX2)

PDIC:

114489723(P2RX2)

PHAS:

123822014(P2RX2)

MMF:	118640087(P2RX2)

PPAM:

129087497(P2RX2)

HAI:	109376154(P2RX2)

RFQ:	117017541(P2RX2)

PALE:

102891282(P2RX2)

PGIG:

120615963(P2RX2)

PVP:	105299556(P2RX2)

RAY:	107511552(P2RX2)

MJV:	108390424(P2RX2)

TOD:	119244221(P2RX2)

SARA:

101549648(P2RX2)

SFUM:

130024779(P2RX2)

SETR:

126001088(P2RX2)

LAV:	100654833(P2RX2)

TMU:

101358869

ETF:	101650151(P2RX2)

MDO:	100027526(P2RX2)

GAS:	123256826(P2RX2)

SHR:	100930241(P2RX2)

AFZ:

127545345

PCW:	110220338(P2RX2)

TVP:	118833219(P2RX2)

PBRV:

138163415(P2RX2)

OAA:	100080197(P2RX2)

TACU:

119942372(P2RX2)

GGA:	101749217(P2RX2)

PCOC:

116228314(P2RX2)

MGP:	100546669(P2RX2)

CJO:	107321092(P2RX2)

TPAI:

128083831(P2RX2)

LMUT:

125701698(P2RX2)

NMEL:

110406225(P2RX2)

APLA:

101790466 119718472

ACYG:

106047467(P2RX2)

CATA:

118259612(P2RX2)

AFUL:

116496162(P2RX2)

AAM:	106487396(P2RX2)

AROW:

112973910(P2RX2)

TGT:	104568206(P2RX2)

DNE:	112987154(P2RX2)

ASN:	102383977(P2RX2)

AMJ:	102563325(P2RX2)

PSS:	102447498(P2RX2)

CMY:	102936772(P2RX2)

CCAY:

125623105(P2RX2)

DCC:	119843744(P2RX2)

CPIC:

101946583(P2RX2)

TST:	117888240(P2RX2)

CABI:

116817867(P2RX2)

MRV:	120386187(P2RX2)

ACS:	100553798(p2rx2)

ASAO:

132780387(P2RX2)

PVT:	110082885(P2RX2)

SUND:

121916647(P2RX2)

PBI:	103049513(P2RX2)

PMUR:

107285442(P2RX2)

CTIG:

120316740(P2RX2)

PGUT:

117672180(P2RX2)

APRI:

131185509(P2RX2)

PTEX:

113448714(P2RX2)

NSS:	113425761(P2RX2)

VKO:	123030337(P2RX2)

PMUA:

114586835(P2RX2)

PRAF:

128403923(P2RX2)

ZVI:	118076186(P2RX2)

HCG:	128338096(P2RX2)

GJA:	107122109(P2RX2)

STOW:

125442832(P2RX2)

EMC:	129341494(P2RX2)

XLA:	108715297(p2rx2.L)

XTR:	101730278(p2rx2)

NPR:	108786245(P2RX2)

RTEM:

120939799(P2RX2)

PWL:	138266177(P2RX2)

MUO:	115480168(P2RX2)

GSH:	117364524(P2RX2)

DRE:	387297(p2rx2)

SRX:	107741507(p2rx2)

SANH:

107704555

SGH:	107599138(p2rx2)

CCAR:

109079174 109079205

CAUA:

113067937 113072086

CGIB:

127958417 127988043

PTET:

122345776(p2rx2)

LROH:

127165733(p2rx2)

OMC:	131541226(p2rx2)

PPRM:

120470048(p2rx2)

RKG:	130088114(p2rx2)

MAMB:

125267331(p2rx2)

CIDE:

127513263

CERY:

137034616(p2rx2)

MASI:

127430453 127439696

TROS:

130546646(p2rx2)

TDW:	130419744(p2rx2)

MANU:

129439696(p2rx2)

PDAB:

135732145(p2rx2)

IPU:

108255423

IFU:	128625598(p2rx2)

PHYP:

113537142(p2rx2)

SMEO:

124380902(p2rx2)

TFD:	113653388(p2rx2)

TVC:	132854775(p2rx2)

CGAR:

128509584(p2rx2)

NGRA:

132872140(p2rx2)

TRN:	134335427(p2rx2)

AMEX:

103041467(p2rx2)

CMAO:

118827366(p2rx2)

EEE:

113585601

CHAR:

105891674(p2rx2)

SPIL:

134089521(p2rx2)

TRU:	101079700(p2rx2)

TFS:	130525618(p2rx2)

TNG:	GSTEN00029543G001

LCO:

104921248

NCC:	104945036(p2rx2)

TBEN:

117476069(p2rx2)

CGOB:

115013367(p2rx2)

PGEO:

117453066(p2rx2)

GACU:

117535777(p2rx2)

EMAC:

134873988(p2rx2)

ELY:	117253027(p2rx2)

EFO:	125890640(p2rx2)

PLEP:

121944966(p2rx2)

SLUC:

116056918(p2rx2)

ECRA:

117945344(p2rx2)

ESP:	116689801(p2rx2)

PFLV:

114556003

GAT:	120830231(p2rx2)

PPUG:

119225542(p2rx2)

AFB:	129101629(p2rx2)

CLUM:

117736581(p2rx2)

PSWI:

130196935(p2rx2)

CANA:

137778955(p2rx2)

CVE:	137867289(p2rx2)

MSAM:

119891181(p2rx2)

SCHU:

122876474(p2rx2)

CUD:	121510310(p2rx2)

SPUL:

138610779(p2rx2)

LMIX:

132974217(p2rx2)

ALAT:

119020129(p2rx2)

ASTR:

137593033(p2rx2)

MZE:	101477055(p2rx2)

ONL:

100711766

OAU:	116332510(p2rx2)

OLA:	101171837(p2rx2)

OML:	112148581(p2rx2)

CSAI:

133450463(p2rx2)

XMA:	102217025(p2rx2)

XCO:	114154104(p2rx2)

XHE:	116729255(p2rx2)

PRET:

103470348(p2rx2)

PFOR:

103142898(p2rx2)

PLAI:

106944560(p2rx2)

PMEI:

106918468(p2rx2)

GAF:	122828024(p2rx2)

PPRL:

129372097(p2rx2)

CVG:	107100042(p2rx2)

CTUL:

119786560(p2rx2)

GMU:	124878182(p2rx2)

NFU:	107393956(p2rx6)

KMR:	108234517(p2rx2)

ALIM:

106521654(p2rx2)

NWH:	119413393(p2rx2)

AOCE:

111568319(p2rx2)

EJA:	138191680(p2rx2)

BFRE:

138627258(p2rx2)

MCEP:

125012382(p2rx2)

CSEM:

103397305(p2rx2)

POV:	109638200(p2rx2)

SSEN:

122769846(p2rx2)

SSOE:

131464081(p2rx2)

HHIP:

117768133(p2rx2)

HSP:	118115333(p2rx2)

PPLT:

128438629(p2rx2)

SMAU:

118313989(p2rx2)

LCF:

108878121

SDU:	111231133(p2rx2)

SLAL:

111660379(p2rx2)

XGL:	120805062(p2rx2)

HCQ:

109514090

SSCV:

125994253(p2rx2)

SBIA:

133499472(p2rx2)

PEE:	133399793(p2rx2)

PTAO:

133475884(p2rx2)

BPEC:

110156760(p2rx2)

ENY:	140346921(p2rx2)

MALB:

109956991

BSPL:

114862904(p2rx2)

SJO:	128365070(p2rx2)

SSCO:

133979504(p2rx2)

GMH:	115554196(p2rx2)

SASA:

106580269 106585656

STRU:

115164867 115199611

OTW:	112249662 112263294(p2rx2)

OMY:	110525350 110535754(p2rx2)

OGO:	124033394 124035149(p2rx2)

ONE:	115111327 115140543

OKI:	109872964 109895057

OKE:	118357895 118392927

OMM:	135514359(p2rx2) 135547325

OCLA:

139389920 139411932

SALP:

111957983 111974915

SNH:	120054008 120062680(p2rx2)

CCLU:

121550888 121584066(p2rx2)

ELS:	105014432(p2rx2)

OEP:	134015143(p2rx2)

SFM:	108932542(p2rx2)

PKI:	111854914(p2rx2)

AANG:

118206946(p2rx2)

AROT:

135264769(p2rx2)

CCOG:

133140956(p2rx2)

LOC:	102692783(p2rx2)

PSPA:

121307677 121307684

ARUT:

117426248 117427710

PSEX:

120540737(p2rx2)

LCM:	102355205(P2RX2)

CMK:	103184094(p2rx2)

RTP:

CPLA:

HOC:

LERI:

PMRN:

LRJ:

Reference

PMID:7523952

Authors

Brake AJ, Wagenbach MJ, Julius D

Title

New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor.

Journal

Nature 371:519-23 (1994)
DOI:10.1038/371519a0

Sequence

[rno:114115]

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