KEGG ORTHOLOGY: K05218

ORTHOLOGY: K05218

Entry

K05218                      KO

Symbol

P2RX4

Name

P2X purinoceptor 4

Pathway

map04020

Calcium signaling pathway

map04080

Neuroactive ligand-receptor interaction

map04082

Neuroactive ligand signaling

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K05218  P2RX4; P2X purinoceptor 4
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05218  P2RX4; P2X purinoceptor 4
   04082 Neuroactive ligand signaling
    K05218  P2RX4; P2X purinoceptor 4
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K05218  P2RX4; P2X purinoceptor 4
Ion channels [BR:ko04040]
Ligand-gated channels
  ATP-gated cation channel (P2X)
   K05218  P2RX4; P2X purinoceptor 4

Other DBs

GO:	0001614 0004931

TC:	1.A.7.1.4 1.A.7.1.5 1.A.7.3.1

Genes

HSA:	5025(P2RX4)

PTR:	452319(P2RX4)

PPS:	100990374(P2RX4)

GGO:	129525894(P2RX4)

PON:	100458831(P2RX4)

PPYG:

129009709(P2RX4)

NLE:	100589361(P2RX4)

HMH:	116477796(P2RX4)

SSYN:

129460133(P2RX4)

MCC:	702536(P2RX4)

MCF:	102120732(P2RX4)

MTHB:

126930646

MNI:	105494591(P2RX4)

CSAB:

103239278(P2RX4)

CATY:

105590958(P2RX4)

PANU:

101020128(P2RX4)

TGE:	112635290(P2RX4)

MLEU:

105527938(P2RX4)

RRO:	104666272(P2RX4)

RBB:	108529639(P2RX4)

PTEH:

111537851(P2RX4)

CANG:

105516397(P2RX4)

CJC:	100396434(P2RX4)

SBQ:	101046432(P2RX4)

CIMI:

108315124(P2RX4)

ANAN:

105728527(P2RX4)

CSYR:

103262346(P2RX4)

MMUR:

105880915(P2RX4)

LCAT:

123626081(P2RX4)

PCOQ:

105825649(P2RX4)

OGA:	100958290(P2RX4)

MMU:	18438(P2rx4)

MCAL:

110294532(P2rx4)

MPAH:

110312799(P2rx4)

RNO:	29659(P2rx4)

ANU:	117697636(P2rx4)

ASYL:

127672614(P2rx4)

MUN:	110545323(P2rx4)

CGE:

100752103

MAUA:

101840398(P2rx4)

PROB:

127216073(P2rx4)

PLEU:

114704556(P2rx4)

MORG:

121446233(P2rx4)

MFOT:

126504176

AAMP:

119824911(P2rx4)

NGI:	103739074(P2rx4)

HGL:	101723201(P2rx4)

CPOC:

100716323(P2rx4)

CCAN:

109699537(P2rx4)

DORD:

105990682(P2rx4)

DSP:	122098569(P2rx4)

PLOP:

125349144(P2rx4)

NCAR:

124990308

MMMA:

107156422(P2rx4)

ITI:	101961921(P2rx4)

OCU:	100008720 127488424

OPI:	101533044(P2RX4)

TUP:	102475496(P2RX4)

GVR:	103588688(P2RX4)

CFA:	448783(P2RX4)

CLUD:

112676517(P2RX4)

VVP:	112935217(P2RX4)

VLG:	121475811(P2RX4)

NPO:	129507501(P2RX4)

AML:	100477528(P2RX4)

UMR:	103661274(P2RX4)

UAH:	113266953(P2RX4)

UAR:	123779281(P2RX4)

ELK:

111156491

LLV:

125081680

MPUF:

101690444(P2RX4)

MNP:	132023136(P2RX4)

MLK:	131811888(P2RX4)

NVS:	122903447(P2RX4)

ORO:	101366441(P2RX4)

EJU:	114219019(P2RX4)

ZCA:	113912956(P2RX4)

MLX:	118018450(P2RX4)

NSU:	110588293(P2RX4)

LWW:	102739388(P2RX4)

FCA:	101080484(P2RX4)

PYU:	121010460(P2RX4)

PCOO:

112870126(P2RX4)

PBG:	122470203(P2RX4)

PVIV:

125148895(P2RX4)

LRUF:

124518342

LGF:	123588220(P2RX4)

AJU:

106967589

PTG:	102972163(P2RX4)

PPAD:

109277676(P2RX4)

PUC:

125914199

PLEZ:

122204078(P2RX4)

HHV:	120221994(P2RX4)

BTA:	338036(P2RX4)

BOM:	102276211(P2RX4)

BIU:	109571456(P2RX4)

BBUB:

102396626(P2RX4)

BBIS:

104989620(P2RX4)

CHX:	102173324(P2RX4)

OAS:	101104013(P2RX4)

BTAX:

128062606(P2RX4)

CSUM:

138093785(P2RX4)

ODA:	120871053(P2RX4)

CCAD:

122423748(P2RX4)

MREE:

136145700(P2RX4)

OVR:	110130509(P2RX4)

MBEZ:

129542225(P2RX4)

SSC:	100157723(P2RX4)

CFR:	102522360(P2RX4)

CBAI:

105080623(P2RX4)

CDK:	105102503(P2RX4)

VPC:	102532106(P2RX4)

BACU:

103001338(P2RX4)

BMUS:

118906965(P2RX4)

LVE:	103091066(P2RX4)

OOR:	101282492(P2RX4)

LALB:

132503881(P2RX4)

DLE:	111186859(P2RX4)

PCAD:

102975317(P2RX4)

PSIU:

116764905(P2RX4)

NASI:

112408770(P2RX4)

ECB:	100059626(P2RX4)

EPZ:	103541695(P2RX4)

EAI:	106842290(P2RX4)

MYB:	102263539(P2RX4)

MYD:	102753054(P2RX4)

MMYO:

118678238(P2RX4)

MLF:	102422146(P2RX4)

MDT:	132221921(P2RX4)

MYUM:

138997977(P2RX4)

PKL:	118725463(P2RX4)

EFUS:

103287034(P2RX4)

MNA:	107529591(P2RX4)

DRO:	112310459(P2RX4)

SHON:

118991082(P2RX4)

AJM:	119048805(P2RX4)

PDIC:

114509709(P2RX4)

PHAS:

123822368(P2RX4)

MMF:	118640233(P2RX4)

PPAM:

129087305(P2RX4)

HAI:	109386080(P2RX4)

RFQ:	117017318(P2RX4)

PALE:

102879399(P2RX4)

PGIG:

120616084(P2RX4)

PVP:	105289205(P2RX4)

RAY:	107513229(P2RX4)

MJV:	108384599(P2RX4)

TOD:	119245007 119245009

SFUM:

130016429(P2RX4)

SETR:

126030608(P2RX4)

LAV:	100670469(P2RX4)

TMU:

111821041

ETF:	101660262(P2RX4)

DNM:	101413767(P2RX4)

MDO:	100618270(P2RX4)

GAS:	123244804(P2RX4)

SHR:	100923139(P2RX4)

AFZ:

127545451

PCW:	110196831(P2RX4)

PBRV:

138156165(P2RX4)

OAA:	100090378(P2RX4)

TACU:

119941980(P2RX4)

GGA:	374166(P2RX4)

MGP:	100543578(P2RX4)

CJO:	107321119(P2RX4)

TPAI:

128084638(P2RX4)

LMUT:

125701877(P2RX4)

NMEL:

110406319(P2RX4)

APLA:

101791189(P2RX4)

ACYG:

106031147

CATA:

118257240(P2RX4)

AFUL:

116496318(P2RX4)

TGU:	100232437(P2RX4)

LSR:	110471761(P2RX4)

SCAN:

103818168(P2RX4)

PMOA:

120509615(P2RX4)

OTC:	121338860(P2RX4)

PRUF:

121365058(P2RX4)

ATRC:

139598542(P2RX4)

GFR:	102039359(P2RX4)

FAB:	101815352(P2RX4)

OMA:	130259709(P2RX4)

PHI:	102112929(P2RX4)

PMAJ:

107211610(P2RX4)

CCAE:

111936388(P2RX4)

CCW:	104688704(P2RX4)

CBRC:

103616025(P2RX4)

ACOE:

138119022(P2RX4)

ETL:	114054955(P2RX4)

ZAB:	102062131(P2RX4)

ZLE:	135454819(P2RX4)

ACHL:

103810654(P2RX4)

SVG:	106852399(P2RX4)

MMEA:

130580335(P2RX4)

HRT:	120760411(P2RX4)

SATI:

136369065(P2RX4)

CCIC:

134050833(P2RX4)

FPG:	101919147(P2RX4)

FCH:	102054376(P2RX4)

CCRI:

104169579(P2RX4)

NNT:	104408160(P2RX4)

SHAB:

115614312(P2RX4)

TALA:

104357788(P2RX4)

ACHC:

115345424(P2RX4)

HALD:

104310854(P2RX4)

HLE:	104840899(P2RX4)

AGEN:

126041145

HHAR:

128145401(P2RX4)

GCL:

127022736

CSTI:

104550892(P2RX4)

LDI:	104347774(P2RX4)

MNB:	103772408(P2RX4)

DPUB:

104308396(P2RX4)

PPUS:

135188898(P2RX4)

AVIT:

104270965(P2RX4)

BRHI:

104501006

EGZ:	104130145(P2RX4)

NNI:	104020830(P2RX4)

PCRI:

104025157

PCAO:

104052836(P2RX4)

PADL:

103914557(P2RX4)

AFOR:

103902796(P2RX4)

FGA:	104081678(P2RX4)

GSTE:

104256118(P2RX4)

CLV:	102085962(P2RX4)

MUI:	104545142(P2RX4)

PGUU:

104469699(P2RX4)

PLET:

104618217(P2RX4)

EHS:	104513713(P2RX4)

CMAC:

104477998(P2RX4)

CUCA:

104058853(P2RX4)

TEO:	104383384(P2RX4)

BREG:

104629743(P2RX4)

OHA:	104339355(P2RX4)

ACAR:

104529004(P2RX4)

CPEA:

104389439(P2RX4)

CVF:	104282261(P2RX4)

RTD:	128916917(P2RX4)

CRID:

134522725(P2RX4)

AAM:	106497654(P2RX4)

AROW:

112962519(P2RX4)

TGT:	104567205(P2RX4)

SCAM:

104138889(P2RX4)

ASN:	102376745(P2RX4)

AMJ:	102564687(P2RX4)

CPOO:

109312622(P2RX4)

GGN:	109290603(P2RX4)

PSS:	102443940(P2RX4)

CMY:	102931602(P2RX4)

CCAY:

125623009

DCC:	119843713(P2RX4)

CPIC:

101943499(P2RX4)

TST:	117887973(P2RX4)

CABI:

116836787

ACS:	100561452(p2rx4)

ASAO:

132781326(P2RX4)

PVT:	110083823(P2RX4)

SUND:

121917635 121917639 121917644 121917649 121917653 121917657

PBI:	103057916(P2RX4)

PMUR:

107286969(P2RX4)

CTIG:

120316797(P2RX4)

TSR:	106554946(P2RX4)

PGUT:

117672211(P2RX4)

APRI:

131185578(P2RX4)

PTEX:

113448689(P2RX4)

NSS:	113424926(P2RX4)

VKO:	123028585(P2RX4)

PMUA:

114586135(P2RX4)

PRAF:

128404343(P2RX4)

ZVI:	118075714(P2RX4)

HCG:	128337880(P2RX4)

GJA:	107115912(P2RX4)

STOW:

125443076(P2RX4)

EMC:	129341034(P2RX4)

XLA:	398206(p2rx4.L)

XTR:	100489363(p2rx4)

NPR:	108787253(P2RX4)

RTEM:

120933552(P2RX4)

BBUF:

120988573(P2RX4)

BGAR:

122924542(P2RX4)

PWL:	138266278(P2RX4)

MUO:	115480640(P2RX4)

GSH:	117365630(P2RX4)

DRE:	259258(p2rx4a) 387301(p2rx4b)

SRX:	107724884 107736919 107737869

SANH:

107661306(p2rx4) 107667528 107692318

SGH:	107574448 107595680(p2rx4) 107602829

CCAR:

109081446(p2rx4a) 109108747(p2rx4b)

CAUA:

113038768 113047077 113106811 113106812 113106813 113106814 113107697 113107949

CGIB:

127952271 127962940 127986607

PTET:

122326151(p2rx4a) 122350312(p2rx4b)

LROH:

127152141(p2rx4a) 127164209 127164312 127169937(p2rx4b)

OMC:	131529088(p2rx4a) 131546133(p2rx4b)

PPRM:

120484532(p2rx4b) 120490744(p2rx4a)

RKG:	130072372(p2rx4b) 130076908(p2rx4a) 130097703

MAMB:

125249482 125252250(p2rx4a) 125279687(p2rx4b)

CIDE:

127503386 127517399

CERY:

137005469 137012332(p2rx4a) 137026403(p2rx4b)

MASI:

127424239 127428914

TROS:

130568365(p2rx4b) 130569989(p2rx4a)

TDW:	130407757(p2rx4a) 130439875(p2rx4b)

MANU:

129423635(p2rx4a)

PDAB:

135721716(p2rx4a)

IPU:	108279151(p2rx4a)

IFU:	128622144(p2rx4a)

PHYP:

113535677(p2rx4)

SMEO:

124398095(p2rx4a)

TFD:	113634521(p2rx4a)

TVC:	132859535(p2rx4a)

CGAR:

128507960(p2rx4a)

NGRA:

132895263(p2rx4a)

TRN:	134330803(p2rx4a)

AMEX:

103024165(p2rx4a)

CMAO:

118802308(p2rx4b) 118819934(p2rx4a)

EEE:	113588026 113590048(p2rx4)

CHAR:

105893268 105893294(p2rx4a) 105911349(p2rx4b)

SPIL:

134070484 134071280(p2rx4a) 134089131(p2rx4b)

TRU:

101070550

TFS:	130525694(p2rx4b)

TNG:	GSTEN00021589G001

LCO:

104926383

TBEN:

117484791(p2rx4b)

CGOB:

115014059(p2rx4)

PGEO:

117452642(p2rx4b)

EMAC:

134873925(p2rx4b)

ELY:	117253110(p2rx4b)

EFO:	125889717(p2rx4b)

PLEP:

121938571 121944940(p2rx4b)

SLUC:

116050513 116050519

ECRA:

117945087(p2rx4b)

ESP:

PFLV:

GAT:

PPUG:

AFB:	129100689(p2rx4b)

CANA:

137779054(p2rx4b)

CVE:	137879840(p2rx4b)

MSAM:

119887933 119891749(p2rx4b)

SCHU:

122877054(p2rx4b)

CUD:	121509400(p2rx4b)

SPUL:

138610538(p2rx4b)

LMIX:

132973699(p2rx4b)

ALAT:

119019083(p2rx4b)

MZE:	101483332(p2rx4)

ONL:	100700744(p2rx4)

OAU:	116322672(p2rx4b)

OLA:	101168548(p2rx4)

OML:

CSAI:

XMA:

XCO:

XHE:

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122828394(p2rx4b)

PPRL:

129373059(p2rx4b)

CVG:

107098781

CTUL:

119775608(p2rx4b)

GMU:	124877472(p2rx4b)

NFU:

107393858

KMR:	108234961(p2rx4b)

ALIM:

106527483

NWH:

119413557

AOCE:

111583074(p2rx4b)

MCEP:

125012897(p2rx4b)

POV:	109633708(p2rx4)

SSEN:

122770109

SSOE:

131464211(p2rx4b)

HHIP:

117767464(p2rx4b)

HSP:	118114978(p2rx4b)

PPLT:

128438032(p2rx4b)

SMAU:

118314355(p2rx4b)

LCF:	108878573(p2rx4b)

SDU:

111229778

SLAL:

111647979

XGL:	120805536(p2rx4b)

BPEC:

110163349

MALB:

109959758

BSPL:

114863252(p2rx4b)

SJO:	128364588 128364834

SSCO:

133978767(p2rx4b)

GMH:

115546028

SASA:

100195175(p2rx4) 106579965

STRU:

115159998 115199959

OTW:	112220063(p2rx4a) 112263060

OMY:	110523248(p2rx4a) 110535053(p2rx4b)

OGO:	123989413(p2rx4a) 124036175

ONE:	115119074 115139907

OKI:	109868221 109894887

OKE:	118358209 118387323(p2rx4a)

OMM:	135514228 135518285(p2rx4a)

OCLA:

139390136 139408385

SALP:

111958199 112080615

SNH:	120025659(p2rx4a) 120063586

CCLU:

121551227 121582057(p2rx4a)

ELS:	105007886(p2rx4) 105014178 105014233 106024601

OEP:	134014947(p2rx4b) 134038940(p2rx4a)

SFM:	108921859 108933374(p2rx4)

PKI:	111842061(p2rx4)

AANG:

118206984(p2rx4b) 118212785(p2rx4a)

AROT:

135239388(p2rx4a) 135265035(p2rx4b)

CCOG:

133105569(p2rx4a) 133139946(p2rx4b)

LOC:

102693324

PSPA:

121297618 121299889 121300249

ARUT:

117395349 117426704 117962990 117973332

PSEX:

120540934(p2rx4b)

LCM:	102346773(P2RX4)

CMK:	103184313(p2rx4a)

RTP:

109913954

CPLA:

122562670

HOC:

132827340

LERI:

129709408(p2rx4a)

PMRN:

116937928 116938822 116957483

BFO:

118426535

BBEL:

109464342

SPU:	115926462 587360 591536

LPIC:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:	117105363 117113877 117121889

SKO:

PFLL:

IEL:

HAMR:

FCD:	110846453 110846766 110863606

DPX:	DAPPUDRAFT_206200 DAPPUDRAFT_310786

DMK:

DPZ:

EAF:

LSM:

TCF:	131882791 131892668

DSV:	119443740 119445231 119446726

RSAN:

119389226 119389498

RMP:	119163828 119181902

CSCU:

CVS:

PTEP:

ABRU:

UDV:	129224624 129227624

SDM:	118192988 118194912

LPOL:

106459345 106464158

PMEO:

129583279 129584510 129584719 129587013 129588545 129588627 129588938 129589136 129589137 129589150 129591984 129595459 129595461 129595480 129599140

LGI:	LOTGIDRAFT_207736

PVUL:

126823336

PCAN:

112562260

LSAX:

138975984 138977174

BGT:	106075106 106075112

GAE:	121368332 121391197

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

MCAF:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:	106154691 106162933

SMM:	Smp_099640 Smp_179310

SHX:	MS3_00005718(P2RX4_1) MS3_00006771(P2RX4_4)

OVI:	T265_00119 T265_00120 T265_00386 T265_14191

EGL:

EGR_02600

LLON:

135483115 135491520

NVE:	116619006 5513129

EPA:

110239681

ATEN:

116288605 116288810 116288811

ADF:

107358498

AMIL:

114957827 114960300

MCAZ:

138046948 138047021 138047044

MFOO:

137972066 137975984

PDAM:

113665529 113686177

SPIS:

111344838 111345319

DGT:	114523648 114523734 114524099

XEN:	124435278 124435279

HMG:

100211566

HSY:

130623910

RES:

135683197

TAD:	TRIADDRAFT_57279 TRIADDRAFT_59819

AQU:

100636400

OLU:	OSTLU_32638

OTA:	OT_ostta07g02280

BPG:	Bathy02g03360

MBR:	MONBRDRAFT_31366

SRE:	PTSG_04102

» show all

Reference

PMID:9016352

Authors

Garcia-Guzman M, Soto F, Gomez-Hernandez JM, Lund PE, Stuhmer W

Title

Characterization of recombinant human P2X4 receptor reveals pharmacological differences to the rat homologue.

Journal

Mol Pharmacol 51:109-18 (1997)
DOI:10.1124/mol.51.1.109

Sequence

[hsa:5025]

LinkDB

DBGET integrated database retrieval system