KEGG ORTHOLOGY: K05224

ORTHOLOGY: K05224

Entry

K05224                      KO

Symbol

GRP

Name

gastrin-releasing peptide

Pathway

map04080

Neuroactive ligand-receptor interaction

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05224  GRP; gastrin-releasing peptide
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides
    K05224  GRP; gastrin-releasing peptide
Cytokines and neuropeptides [BR:ko04052]
Neuropeptides
  GPCR binding
   K05224  GRP; gastrin-releasing peptide

Genes

HSA:

2922(GRP)

PTR:	736808(GRP)

PPS:	100976855(GRP)

GGO:	101149140(GRP)

PON:	100454272(GRP)

PPYG:

129018860(GRP)

NLE:	100591635(GRP)

HMH:	116468070(GRP)

SSYN:

129492550(GRP)

MCC:	696983(GRP)

MCF:	102124124(GRP)

MTHB:

126941442

MNI:	105477049(GRP)

CSAB:

103244202(GRP)

CATY:

105589979(GRP)

PANU:

101010701(GRP)

TGE:	112611507(GRP)

MLEU:

105533294(GRP)

RRO:	104673013(GRP)

RBB:	108541044(GRP)

TFN:	117098811(GRP)

PTEH:

111546839(GRP)

CANG:

105517015(GRP)

CJC:	100390073(GRP)

SBQ:	101046609(GRP)

CIMI:

108304570

ANAN:

105712986(GRP)

CSYR:

103259860(GRP)

MMUR:

105860588(GRP)

LCAT:

123621599

ERUF:

138383258(GRP)

PCOQ:

105816364(GRP)

OGA:	100951231(GRP)

MMU:	225642(Grp)

MCAL:

110285048(Grp)

MPAH:

110333491(Grp)

RNO:	171101(Grp)

MCOC:

116087695(Grp)

ANU:	117720148(Grp)

ASYL:

127663815(Grp)

MUN:	110546635(Grp)

CGE:	100769410(Grp)

MAUA:

121138836

PROB:

127234121(Grp)

PLEU:

MORG:

MFOT:

AAMP:

NGI:	103739620(Grp)

HGL:	101722365(Grp)

CPOC:

100728828(Grp)

CCAN:

109690916(Grp)

DORD:

105987629(Grp)

DSP:

122104390

DMER:

138831561(Grp)

PLOP:

NCAR:

MMMA:

ITI:

OCU:

OPI:

OCZ:

TUP:	102493575(GRP)

GVR:	103596539(GRP)

CFA:	610154(GRP)

CLUD:

112643755

VVP:	112919218(GRP)

VLG:

121482061

NPO:	129495567 129514615

AML:	100477162(GRP)

UMR:

103676284

UAH:	113253153(GRP)

UAR:

123787520

ELK:

111154205

LLV:

125082307

MPUF:

101692309(GRP)

MNP:	132023961(GRP)

MLK:	131811360(GRP)

NVS:

122901911

ORO:	101365129(GRP)

EJU:	114208772(GRP)

ZCA:

113912964

MLX:	118004573(GRP)

MANO:

123840978(GRP)

NSU:

110577134

LWW:	102748162(GRP)

FCA:

109493482

PYU:

121032868

PCOO:

112868155(GRP)

PBG:

122470809

PVIV:

125149526(GRP)

LRUF:

124516977

LGF:

123587869

AJU:

106978893

PTG:	102949197(GRP)

PPAD:

109275660(GRP)

PUC:

125914731

PLEZ:

122203725

HHV:

120230800

BTA:	615323(GRP)

BOM:	102265786(GRP)

BBUB:

102394967

BKE:	129636067(GRP) 129641496

BBIS:

104999286(GRP)

CHX:	102174351(GRP)

OAS:	443332(GRP)

BTAX:

128067548(GRP)

CSUM:

138097678(GRP)

ODA:

120880886

CCAD:

122425555

MREE:

136167683(GRP)

OVR:	110148173(GRP)

MBEZ:

129549605(GRP)

SSC:	102166444(GRP)

CFR:	102522045(GRP)

CBAI:

105073994(GRP)

CDK:	105088988(GRP)

VPC:	102539345(GRP)

BACU:

103009097(GRP)

BMUS:

118880216

LVE:	103082816(GRP)

OOR:	101273188(GRP)

LALB:

132503859(GRP)

GMF:	115859210(GRP)

DDP:	132436645(GRP)

DLE:	111180221(GRP)

PCAD:

102976434(GRP)

PSIU:

116739309(GRP)

PPHC:

136133182(GRP)

NASI:

112406203(GRP)

ECB:	100050124(GRP)

EPZ:	103553885(GRP)

EAI:

106842484

MYB:	102250992(GRP)

MYD:	102751717(GRP)

MMYO:

118663429

MLF:	102426580(GRP)

MDT:	132240290(GRP)

MYUM:

139014569(GRP)

PKL:

118708297

EFUS:

103293282(GRP)

MNA:	107545403(GRP)

DRO:	112322574(GRP)

SHON:

PDIC:

PHAS:

MMF:

PPAM:

129078756(GRP)

HAI:	109381729(GRP)

RFQ:	117011688(GRP)

PALE:

102893745(GRP)

PGIG:

120584659

PVP:	105292729(GRP)

RAY:

107506283

MJV:	108398287(GRP)

TOD:	119243772(GRP)

SFUM:

130016309(GRP)

SETR:

126020576 126020577

LAV:	100663302(GRP)

TMU:

101353662

ETF:

101658332

DNM:	101417168(GRP)

MDO:	103092596(GRP)

GAS:

123231527

SHR:	100921665(GRP)

AFZ:

127560526

PCW:	110213399(GRP)

TVP:

118833911

PBRV:

138171646(GRP) 138172917

MLAO:

141502529(GRP)

OAA:

114810038

TACU:

119925859

GGA:	425213(GRP)

PCOC:

116239179(GRP)

MGP:	104914741(GRP)

CJO:	107325907(GRP)

TPAI:

128074336(GRP)

LMUT:

125686969

APLA:

101804211

AACU:

137847190(GRP)

OJA:	118155958(GRP)

ACYG:

106044900(GRP)

CATA:

118254626(GRP)

AFUL:

116501175(GRP)

TGU:	105760884 116807024

LSR:	110478584(GRP)

SCAN:

103824382(GRP)

PMOA:

120501748

OTC:

121335549

PRUF:

121356130

ATRC:

139585741(GRP)

MAEN:

136569515(GRP)

GFR:	102032029(GRP)

FAB:	101805830(GRP)

OMA:	130265099(GRP)

PHI:	102111052(GRP)

PMAJ:

107198639(GRP)

CCAE:

111940980(GRP)

CCW:

104698607

CBRC:

108448070(GRP)

ACOE:

138103356(GRP)

ETL:	114073658(GRP)

ZAB:	102061469(GRP)

ZLE:	135459718(GRP)

ACHL:

103804543(GRP)

SVG:	106863891(GRP)

MMEA:

130583859(GRP)

HRT:	120765186(GRP)

SATI:

136373743(GRP)

CCIC:

134056750(GRP)

FPG:	101923611(GRP)

FCH:	102060190(GRP)

CCRI:

104162001(GRP)

NNT:	104406690(GRP)

SHAB:

115603172(GRP)

ACUN:

113489840(GRP)

ANOC:

141973718(GRP)

SURA:

141938374(GRP)

TALA:

104369165

ACHC:

115337240

HALD:

104314648(GRP)

HLE:	104841423(GRP)

AGEN:

126036456

HHAR:

128137754(GRP)

BBUT:

142026877(GRP)

GCL:

127027810

CSTI:

104563591(GRP)

LDI:	104348230(GRP)

MNB:	103777312(GRP)

DPUB:

104306259(GRP)

PPUS:

135174507(GRP)

AVIT:

104275534(GRP)

BRHI:

104497883(GRP)

PCRI:

104033368(GRP)

PCAO:

104050175(GRP)

PARX:

142049384(GRP)

PADL:

103922226(GRP)

FGA:	104082409(GRP)

CBOR:

142074868 142075679

GSTE:

104263142(GRP)

CBOY:

140650949(GRP)

MAME:

142403017(GRP)

CLV:	102093899(GRP)

CNIC:

136002437(GRP)

MUI:	104547536(GRP)

PGUU:

104469794(GRP)

PLET:

104617671(GRP)

EHS:	104508591(GRP)

CMAC:

104484107(GRP)

TEO:	104378336(GRP)

BREG:

104637778(GRP)

GAME:

129199478(GRP)

OHA:	104328493(GRP)

ACAR:

104522410(GRP)

CPEA:

104394100(GRP)

CVF:	104283827(GRP)

RTD:	128902125 128902970

CRID:

134508610(GRP)

LMIC:

141736063(GRP)

NARQ:

141476712 141477532

AAM:	106486981(GRP)

AROW:

112968169(GRP)

NPD:	112950052(GRP)

TGT:	104571648(GRP)

DNE:	112985197(GRP)

SCAM:

104139219(GRP)

ASN:	102379265(GRP)

AMJ:	102574239(GRP)

CPOO:

109307709(GRP)

GGN:	109298026(GRP)

PSS:	102450073(GRP)

CIZ:	142013239(GRP)

CMY:

102935854

CCAY:

125637174

LKP:	140912016(GRP)

NDS:	141988072(GRP)

DCC:

119856010

CPIC:

101931231

TST:	117879168(GRP)

CABI:

116822347(GRP)

MRV:

120408303

ACS:	103280257(grp)

ASAO:

132766402(GRP)

PVT:	110085077(GRP)

SUND:

121923465

PBI:	103052962(GRP)

PMUR:

107297634(GRP)

CTIG:

120314707

TSR:	106546944(GRP)

PGUT:

117679980(GRP)

PCAE:

139311518(GRP)

APRI:

131191854(GRP)

PTEX:

113445141(GRP)

NSS:	113411317(GRP)

VKO:

123024104

PMUA:

114606799(GRP)

PRAF:

128423422(GRP)

ZVI:	118077341(GRP)

HCG:	128346377(GRP)

GJA:	107105815(GRP)

STOW:

125436724

EMC:	129334249(GRP)

XLA:	108697117(grp.L) 108706458(grp.S)

XTR:	100493822(grp)

NPR:	108798690(GRP)

RTEM:

120927270

ACAT:

141140391(GRP)

PADS:

140332608(GRP)

BBUF:

120991315

BGAR:

122937386

DTC:	141097567(GRP)

PWL:	138301511(GRP)

MUO:	115462044(GRP)

GSH:	117355246(GRP)

DRE:	559978(grp)

SRX:	107719068 107739661

SANH:

107662931

SGH:	107584633 107600892

CCAR:

CAUA:

CGIB:

PTET:

LROH:

127152764(grp)

OMC:	131528830(grp)

PPRM:

120490766 120490844

RKG:	130090704(grp)

MAMB:

125252819

CERY:

137013214(grp)

MASI:

127428457

TROS:

130570029(grp)

TDW:	130407808(grp)

MANU:

129424503(grp)

PDAB:

135721615(grp)

IPU:

124629177

IFU:	128622861(grp)

PHYP:

113535796

SMEO:

124398121

TFD:

125139868

TVC:	132860027(grp)

CGAR:

128507996(grp)

NGRA:

132894845(grp)

AMEX:

CMAO:

CHAR:

SPIL:

TRU:	105416534(grp)

TFS:	130517503(grp)

LCO:	104928208(grp)

NCC:	104948008(grp)

TBEN:

117476292(grp)

CGOB:

115016929(grp)

PGEO:

117455814(grp)

GACU:

117551283(grp)

EMAC:

134868680(grp)

ELY:	117269761(grp)

EFO:

125905680

PLEP:

121959627

SLUC:

116063018

ECRA:

117959012(grp)

ESP:	116704415(grp)

PFLV:

114570674(grp)

GAT:

120832361

PPUG:

119226989(grp)

AFB:	129101972(grp)

CLUM:

117740708(grp)

PSWI:

130205717(grp)

CANA:

137783825(grp)

CVE:	137868720(grp)

MSAM:

119914769

SCHU:

122865629

EARM:

139301799(grp)

CUD:

121524912

SPUL:

138601767(grp)

LMIX:

132992194(grp)

HTC:	141805674(grp)

ALAT:

119030351

ASTR:

137608989(grp)

PKLU:

139219300(grp)

ONL:	102079627(grp)

OAU:

116331704

OLA:	101167306(grp)

OML:

112163419

CSAI:

133454541(grp)

XMA:	106699609(grp)

XCO:	114149864(grp)

XHE:	116723951(grp)

PRET:

103473880(grp)

PFOR:

103142783(grp)

PLAI:

106952432(grp)

PMEI:

106918645(grp)

GAF:

122819613

PPRL:

129366574 129374089(grp)

CVG:	107085818(grp)

CTUL:

119776501

GMU:

124873077

NFU:	107374703(grp)

ALIM:

106518173(grp)

NWH:

119424883

AOCE:

111583044(grp)

EJA:	138211002(grp)

BFRE:

138628013(grp)

MCEP:

124996875

CSEM:

103390269(grp)

POV:	109626459(grp)

SSEN:

122758430

SSOE:

131445846(grp)

HHIP:

117771570(grp)

HSP:

118125402

PPLT:

128425149(grp)

SMAU:

118285015

SDU:	111234693(grp)

SLAL:

111664734(grp)

XGL:

120806576

MALB:

109960637

BSPL:

114866652(grp)

SJO:	128380625(grp)

SSCO:

133994833(grp)

TTY:	137170905(grp)

GMH:	115532508(grp)

SASA:

106568495(grp)

STRU:

115148267(grp)

OTW:

112259295

OMY:

110536926

OGO:

124000435

ONE:	115104754(grp)

OKI:	109892034(grp)

OCLA:

139421855

SALP:

111981559(grp)

SFON:

129812585(grp)

ELS:	105009494(grp)

OEP:	134033849(grp)

SFM:	108934221(grp)

PKI:	111852614(grp)

AANG:

118212363(grp)

LOC:	107076065(grp)

PSPA:

121295907 121327240

ARUT:

117408374 117420594

PSEX:

120528562

LCM:	106705310(GRP)

CMK:	103184870(grp)

RTP:

109934586

CPLA:

122555351

CPUN:

140482651(grp)

HOC:	132818300(grp)

LERI:

129693971(grp)

HAKA:

140737465(grp)

» show all

Reference

PMID:6207529

Authors

Spindel ER, Chin WW, Price J, Rees LH, Besser GM, Habener JF

Title

Cloning and characterization of cDNAs encoding human gastrin-releasing peptide.

Journal

Proc Natl Acad Sci U S A 81:5699-703 (1984)
DOI:10.1073/pnas.81.18.5699

Sequence

[hsa:2922]

Reference

PMID:28280205

Authors

Yu YQ, Barry DM, Hao Y, Liu XT, Chen ZF

Title

Molecular and neural basis of contagious itch behavior in mice.

Journal

Science 355:1072-1076 (2017)
DOI:10.1126/science.aak9748

Sequence

[mmu:225642]

LinkDB

DBGET integrated database retrieval system