KEGG ORTHOLOGY: K05250

ORTHOLOGY: K05250

Entry

K05250                      KO

Symbol

FSHB

Name

follitropin subunit beta

Pathway

map04024

cAMP signaling pathway

map04080

Neuroactive ligand-receptor interaction

map04081

Hormone signaling

map04912

GnRH signaling pathway

map04913

Ovarian steroidogenesis

Disease

H00255

Hypogonadotropic hypogonadism

H01253

Isolated follicle-stimulating hormone deficiency

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    K05250  FSHB; follitropin subunit beta
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05250  FSHB; follitropin subunit beta
   04081 Hormone signaling
    K05250  FSHB; follitropin subunit beta
09150 Organismal Systems
  09152 Endocrine system
   04912 GnRH signaling pathway
    K05250  FSHB; follitropin subunit beta
   04913 Ovarian steroidogenesis
    K05250  FSHB; follitropin subunit beta
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides
    K05250  FSHB; follitropin subunit beta
Cytokines and neuropeptides [BR:ko04052]
Neuropeptides
  GPCR binding
   K05250  FSHB; follitropin subunit beta

Other DBs

GO:

0016913

Genes

HSA:	2488(FSHB)

PTR:	736618(FSHB)

PPS:	100980625(FSHB)

GGO:	101143526(FSHB)

PON:	100444274(FSHB)

PPYG:

129007534(FSHB)

NLE:	100599170(FSHB)

HMH:	116477278(FSHB)

SSYN:

129484293(FSHB)

MCC:	697317(FSHB)

MCF:	101864888(FSHB)

MTHB:

126934706

MNI:	105471480(FSHB)

CSAB:

103238398(FSHB)

CATY:

105586751(FSHB)

PANU:

101002183(FSHB)

TGE:	112607251(FSHB)

MLEU:

105528729(FSHB)

RRO:	104664220(FSHB)

RBB:	108515635(FSHB)

TFN:	117080538(FSHB)

PTEH:

111554706(FSHB)

CANG:

105507718(FSHB)

CJC:	100398993(FSHB)

SBQ:	101041141(FSHB)

CIMI:

108316947(FSHB)

ANAN:

105717389(FSHB)

CSYR:

103255150(FSHB)

MMUR:

105867785(FSHB)

LCAT:

123641716

PCOQ:

105814581(FSHB)

OGA:	100960721(FSHB)

MMU:	14308(Fshb)

MCAL:

110290424(Fshb)

MPAH:

110319484(Fshb)

RNO:	25447(Fshb)

MCOC:

116092270(Fshb)

ANU:	117704550(Fshb)

ASYL:

127684469(Fshb)

MUN:	110557229(Fshb)

CGE:	100689453(Fshb)

MAUA:

101838709(Fshb)

PROB:

127221949(Fshb) 127226506

PLEU:

114702097(Fshb)

MORG:

121465458(Fshb)

MFOT:

126504705

AAMP:

119815747(Fshb)

NGI:	103748557(Fshb)

HGL:	101717666(Fshb)

CPOC:

100135522(Fshb)

CCAN:

109701465(Fshb)

DORD:

105988102(Fshb)

DSP:	122117922(Fshb)

DMER:

138833754(Fshb)

PLOP:

125362187(Fshb)

NCAR:

124960440

MMMA:

107134387(Fshb)

ITI:	101972212(Fshb)

OCU:	100008946(FSHB)

OPI:	101527214(FSHB)

TUP:	102490240(FSHB) 102494116

GVR:	103593034 103598449(FSHB)

CFA:	485428(FSHB)

CLUD:

112667797(FSHB)

VVP:	112935018(FSHB)

VLG:	121474444(FSHB)

NPO:	129504709(FSHB)

AML:	100482376(FSHB)

UMR:

UAH:

UAR:

ELK:

LLV:

MPUF:

101689508(FSHB)

MNP:	132010693(FSHB)

MLK:	131822097(FSHB)

NVS:	122914298(FSHB)

ORO:

101369871

EJU:

114220014

ZCA:	113915487(FSHB)

MLX:

118015554

NSU:

110575700

LWW:

102745211

FCA:	101084989(FSHB)

PYU:	121043615(FSHB)

PCOO:

112865089

PBG:	122483654(FSHB)

PVIV:

125146636

LRUF:

124506003

LGF:	123601532(FSHB)

AJU:

106970268

PTG:	102970900(FSHB)

PPAD:

109271291(FSHB)

PUC:

125935239

PLEZ:

122200557

HHV:	120223112(FSHB)

BTA:	281171(FSHB) 787432

BOM:	102280966 102281253

BIU:	109569281 109569290

BBUB:

102406062(FSHB) 102406377

BBIS:

104982432 104982433(FSHB)

CHX:	100861299(FSHB)

OAS:	443387(FSHB)

BTAX:

128060511(FSHB)

CSUM:

138092921

ODA:	120876832(FSHB)

CCAD:

122449872 122449873

MREE:

136174572 136174574(FSHB)

OVR:	110132555 110132557

MBEZ:

129554050 129554051

SSC:	396895(FSHB)

CFR:	102510059(FSHB)

CBAI:

105076543(FSHB)

CDK:	105106548(FSHB)

VPC:	102530834(FSHB)

BACU:

102997225 103010492

BMUS:

118899381 118899558

LVE:

103074712

OOR:	101284624(FSHB)

LALB:

132525199(FSHB) 132525893

GMF:	115857604(FSHB)

DLE:	111179753 111179817(FSHB)

PCAD:

102973412(FSHB) 102980603

PSIU:

116758023 116758364(FSHB)

PPHC:

136126339 136126986(FSHB)

NASI:

112412882 112412887

ECB:	100033829(FSHB) 100072550

EPZ:	103540947 103540948(FSHB)

EAI:

106824929

MYB:	102244646(FSHB)

MYD:	102752503(FSHB)

MMYO:

118665437(FSHB)

MLF:	102443318(FSHB)

MDT:	132242235(FSHB)

MYUM:

139017991(FSHB)

PKL:	118712824(FSHB)

EFUS:

103292694(FSHB)

MNA:	107531918(FSHB)

DRO:	112303242(FSHB)

SHON:

118983209(FSHB)

AJM:	119035326(FSHB)

PDIC:

114500606(FSHB)

PHAS:

123810142(FSHB)

MMF:	118628906(FSHB)

PPAM:

129080736(FSHB)

HAI:

109387027

RFQ:	117030205(FSHB)

PALE:

102897414(FSHB)

PGIG:

120605333(FSHB)

PVP:	105293714(FSHB)

RAY:	107515744(FSHB)

MJV:	108396734(FSHB) 108396735

TOD:	119254546(FSHB)

SARA:

101554735(FSHB)

SFUM:

130016497(FSHB)

SETR:

126018014(FSHB)

LAV:	100666748(FSHB)

TMU:

101352587

ETF:	101644371(FSHB)

DNM:	101446392(FSHB) 101446836

MDO:	554190(FSHB)

GAS:	123252555(FSHB)

SHR:	100913282(FSHB)

AFZ:

127540423

PCW:	110192607(FSHB)

TVP:	118852580(FSHB)

PBRV:

138163414(FSHB)

MLAO:

141516527(FSHB)

OAA:	100073363(FSHB)

TACU:

119943931(FSHB)

GGA:	374108(FSHB)

PCOC:

116237957(FSHB)

MGP:	100546857(FSHB)

CJO:	107314372(FSHB)

TPAI:

128085313(FSHB)

LMUT:

125694520(FSHB)

NMEL:

110401638(FSHB)

APLA:

101794876(FSHB)

ACYG:

106033830(FSHB)

CATA:

118249833(FSHB)

AFUL:

116490081(FSHB)

TGU:	100218526(FSHB)

LSR:	110473830(FSHB)

SCAN:

103822089(FSHB)

PMOA:

120509887(FSHB)

OTC:	121345936(FSHB)

PRUF:

121363047(FSHB)

ATRC:

139604187(FSHB)

GFR:	102041181(FSHB)

FAB:	101818979(FSHB)

OMA:	130254055(FSHB)

PHI:	102103936(FSHB)

PMAJ:

107206299(FSHB)

CCAE:

111930471(FSHB)

CBRC:

103624770(FSHB)

ACOE:

138110719 138110720

ETL:	114067293(FSHB)

ZAB:	102072734(FSHB)

ZLE:	135449085(FSHB)

ACHL:

103809672(FSHB)

SVG:	106858100(FSHB)

MMEA:

130584798(FSHB) 130585674

HRT:	120754410(FSHB)

SATI:

136363146(FSHB)

CCIC:

134045369(FSHB)

FPG:	101917385(FSHB)

FCH:	102052820(FSHB)

CCRI:

104161989(FSHB)

NNT:	104402486(FSHB)

SHAB:

115606906(FSHB)

ACUN:

113481321(FSHB)

TALA:

104358339(FSHB)

ACHC:

115351879(FSHB)

HALD:

104323813(FSHB)

HLE:	104829473(FSHB)

AGEN:

126047158

HHAR:

128152743(FSHB)

GCL:

127017181

CSTI:

104549121(FSHB)

LDI:	104343069(FSHB)

MNB:	103770867(FSHB)

DPUB:

104301000(FSHB)

PPUS:

135186258(FSHB)

AVIT:

104272002(FSHB)

BRHI:

104489786(FSHB)

EGZ:	104123340(FSHB)

NNI:	104009427(FSHB)

PCRI:

104027114(FSHB)

PCAO:

104044019(FSHB)

PADL:

103925748(FSHB)

AFOR:

103906803(FSHB)

FGA:	104077469(FSHB)

GSTE:

104264788(FSHB)

CBOY:

140653400(FSHB)

CLV:	102091474(FSHB)

CNIC:

135989645(FSHB)

MUI:	104547438(FSHB)

PGUU:

104464683(FSHB)

PLET:

104624686(FSHB)

EHS:	104502431(FSHB)

CMAC:

104485131(FSHB)

CUCA:

104063821(FSHB)

TEO:	104377606(FSHB)

BREG:

104633358(FSHB)

OHA:	104331798(FSHB)

ACAR:

104527175(FSHB)

CPEA:

104394630(FSHB)

CVF:	104293192(FSHB)

RTD:	128909387(FSHB)

CRID:

134514787(FSHB)

AAM:	106498185(FSHB)

AROW:

112970387(FSHB)

NPD:	112948849(FSHB)

TGT:	104579043(FSHB)

DNE:	112996566(FSHB)

SCAM:

104147082(FSHB)

ASN:	102382808(FSHB)

AMJ:	102557770(FSHB)

CPOO:

109320998(FSHB)

GGN:	109299495(FSHB)

PSS:	102454454(FSHB)

CMY:	102941290(FSHB)

CCAY:

125638816(FSHB)

DCC:	119857550(FSHB)

CPIC:

101932302(FSHB)

TST:	117876895(FSHB)

CABI:

116824522(FSHB)

MRV:	120404851(FSHB)

ACS:	100568157(fshb)

ASAO:

132761863(FSHB)

PVT:	110080031(FSHB)

SUND:

121919298(FSHB)

PBI:	103056045(FSHB)

PMUR:

107291062(FSHB)

CTIG:

120313746(FSHB)

TSR:	106541324(FSHB)

PGUT:

117665393(FSHB)

PCAE:

139327645(FSHB)

APRI:

131200193(FSHB)

PTEX:

113438856(FSHB)

NSS:	113410191(FSHB)

VKO:	123021303(FSHB)

PMUA:

114585054(FSHB)

PRAF:

128414454(FSHB)

ZVI:	118086346(FSHB)

HCG:	128340142(FSHB)

GJA:	107106169(FSHB)

STOW:

125426977(FSHB)

EMC:	129324985(FSHB)

XLA:	108715063(fshb.S) 407843(fshb.L)

XTR:	100495812(fshb)

NPR:	108796389(FSHB)

RTEM:

120916873(FSHB)

ACAT:

141112081(FSHB)

BBUF:

120980855(FSHB)

BGAR:

122921082(FSHB)

DTC:	141090230(FSHB)

PWL:	138283167(FSHB)

MUO:	115467938(FSHB)

GSH:	117352098(FSHB)

SRX:	107740491 107755037

SANH:

107663948 107700395

SGH:	107553068 107554900

CCAR:

109094212(fshb) 122137967

CAUA:

113052489 113105977

PPRM:

120476007(fshb)

MAMB:

125264123(fshb)

IPU:	100304480(fshb)

PHYP:

113540946(fshb)

SMEO:

124380116(fshb)

TFD:	113636801(fshb)

AMEX:

103023472(fshb)

EEE:	113582100(fshb)

LCO:

104920623

MZE:

101487096

ONL:	100534500(fshb)

OAU:

116324003

XMA:

102222187

XCO:

114142578

PRET:

103462710(fshb)

CVG:	107095236(fshb)

NFU:	107381959(fshb)

KMR:	108234775(fshb)

ALIM:

106523543(fshb)

AOCE:

111571034

CSEM:

103398633

POV:

109637185

LCF:	108887820(fshb)

HCQ:

109525784

SASA:

100136362

OTW:	112232279(fshb)

OMY:	100136594(fshb)

SALP:

111969201

SNH:	120025292(fshb)

ELS:

105025971

SFM:	108940908(fshb)

PKI:	111843356(fshb)

CCOG:

133130721(fshb)

LOC:	102685091(fshb)

PSPA:

121295057(fshb)

ARUT:

117432424

CMK:	103174988(fshb)

RTP:	109916573(fshb)

CPLA:

122557642(fshb)

HOC:	132824318(fshb)

LERI:

129705563(fshb) 129715136

HAKA:

PMRN:

LRJ:

Reference

PMID:2494176

Authors

Keene JL, Matzuk MM, Otani T, Fauser BC, Galway AB, Hsueh AJ, Boime I

Title

Expression of biologically active human follitropin in Chinese hamster ovary cells.

Journal

J Biol Chem 264:4769-75 (1989)

Sequence

[hsa:2488]

Reference

PMID:9741710

Authors

Ulloa-Aguirre A, Timossi C

Title

Structure-function relationship of follicle-stimulating hormone and its receptor.

Journal

Hum Reprod Update 4:260-83 (1998)
DOI:10.1093/humupd/4.3.260

LinkDB

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