KEGG   ORTHOLOGY: K05831
Entry
K05831                      KO                                     
Symbol
lysK, argE
Name
[amino group carrier protein]-lysine/ornithine hydrolase [EC:3.5.1.130 3.5.1.132]
Pathway
map00220  Arginine biosynthesis
map00300  Lysine biosynthesis
map01100  Metabolic pathways
map01210  2-Oxocarboxylic acid metabolism
map01230  Biosynthesis of amino acids
Module
M00031  Lysine biosynthesis, mediated by LysW, 2-aminoadipate => lysine
M00763  Ornithine biosynthesis, mediated by LysW, glutamate => ornithine
Reaction
R09779  LysW-gamma-L-lysine amidohydrolase
R10933  LysW-L-ornithine amidohydrolase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    K05831  lysK, argE; [amino group carrier protein]-lysine/ornithine hydrolase
   00220 Arginine biosynthesis
    K05831  lysK, argE; [amino group carrier protein]-lysine/ornithine hydrolase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.130  [amino group carrier protein]-lysine hydrolase
     K05831  lysK, argE; [amino group carrier protein]-lysine/ornithine hydrolase
    3.5.1.132  [amino group carrier protein]-ornithine hydrolase
     K05831  lysK, argE; [amino group carrier protein]-lysine/ornithine hydrolase
Other DBs
COG: COG0624
Genes
MSD: MYSTI_01363
MFB: MFUL124B02_07570
MLAN: JY572_19545
CCX: COCOR_02071(lysK)
PPAK: JY651_31960
AVM: JQX13_36415
CTH: Cthe_2568
CTX: Clo1313_0154
GEK: kuro4_23300
SFA: Sfla_0118
STRP: F750_6906
SALJ: SMD11_6705
SESP: BN6_56690
CAI: Caci_6288
RCA: Rcas_3459
CAU: Caur_1204
CAG: Cagg_2180
HAU: Haur_3310
ATM: ANT_12370(lysK)
CAP: CLDAP_41050(lysK)
TTR: Tter_0317
TRO: trd_1520
STI: Sthe_0214
DRA: DR_1413
DGE: Dgeo_1391
DDR: Deide_17960(lysK)
DFC: DFI_03165
DGA: DEGR_27060(lysK)
DAH: DAETH_12030(lysK)
TRA: Trad_1404
TTH: TT_C1396
TTJ: TTHA1757(TTHA1757)
TAQ: TO73_0259
MRB: Mrub_0027
TAI: Taci_0451
TLI: Tlie_1473
PFU: PF1686
PFI: PFC_10175
PHO: PH1715(PH1715)
PAB: PAB0294(argE)
PYN: PNA2_0325
PYS: Py04_1632
TKO: TK0274
THS: TES1_0511
HHB: Hhub_3652(argE)
HALH: HTSR_0668(argE)
HHSR: HSR6_0694(argE)
HSU: HLASF_2141(argE2)
HSF: HLASA_2175(argE2)
HAHS: HSRCO_2863(argE4)
SALI: L593_07905
HARA: AArcS_3065(argE2)
HMA: rrnAC2674(gltCP)
HHI: HAH_3079(argE1)
NPH: NP_5266A(argE)
NMO: Nmlp_1239(argE)
HUT: Huta_1498
HTI: HTIA_1543
HASV: SVXHr_0128(argE)
HABN: HBNXHr_0125(argE)
HMU: Hmuk_0776
HALL: LC1Hm_3292(argE3)
HDS: HSR122_1701(argE)
HWA: HQ_3718A(argE2)
HWC: Hqrw_4133(argE2)
HVO: HVO_0042(argE)
HLN: SVXHx_0040(arge)
HME: HFX_0042(argE)
HLA: Hlac_2612
HDF: AArcSl_0039(argE)
HAAA: AArcCO_0041(argE)
HTU: Htur_0324
NMG: Nmag_1757(argE)
NAT: NJ7G_0259
PTO: PTO1468
FAI: FAD_0509(lysK)
CDIV: CPM_0544
APE: APE_1467.1(lysK)
ACJ: ACAM_0925(lysK)
IHO: Igni_0664
IIS: EYM_06525
IAG: Igag_1750
PABI: PABY_17830
PARE: PYJP_07950
STO: STK_01900(lysK)
SSO: SSO0162
SOL: Ssol_1139
SSOA: SULA_1175
SSOL: SULB_1176
SSOF: SULC_1174
SCAS: SACC_00740
SAI: Saci_0756
SID: M164_1984
SII: LD85_2239
SIH: SiH_1922
SIR: SiRe_1849
SIC: SiL_1831
MSE: Msed_0170
MEMJ: MJ1HA_0249
MCN: Mcup_1903
AHO: Ahos_0889
ACIH: HS5_22640
CSTY: KN1_18110
STEP: IC006_1908
PAI: PAE2798
PIS: Pisl_1394
PCL: Pcal_1259
PAS: Pars_0867
PYR: P186_1739
POG: Pogu_1471
TNE: Tneu_1861
CMA: Cmaq_1676
TTN: TTX_0118(lysK_argE)
TUZ: TUZN_1280
VDI: Vdis_0199
VMO: VMUT_1537
KCR: Kcr_0814
NMR: Nmar_1296
NCT: NMSP_0392
NGA: Ngar_c14550(lysK)
NVN: NVIE_002650(lysK)
NEV: NTE_01581
TAA: NMY3_02229(dapE_2)
NFN: NFRAN_2991(dapE)
NCV: NCAV_1408
NBV: T478_1051
NDV: NDEV_1631
CCAI: NAS2_0273
BARB: AOA66_0023
 » show all
Reference
  Authors
Miyazaki J, Kobashi N, Fujii T, Nishiyama M, Yamane H
  Title
Characterization of a lysK gene as an argE homolog in Thermus thermophilus HB27.
  Journal
FEBS Lett 512:269-74 (2002)
DOI:10.1016/S0014-5793(02)02290-1
  Sequence
[tth:TT_C1396]
Reference
  Authors
Horie A, Tomita T, Saiki A, Kono H, Taka H, Mineki R, Fujimura T, Nishiyama C, Kuzuyama T, Nishiyama M
  Title
Discovery of proteinaceous N-modification in lysine biosynthesis of Thermus thermophilus.
  Journal
Nat Chem Biol 5:673-9 (2009)
DOI:10.1038/nchembio.198
Reference
  Authors
Ouchi T, Tomita T, Horie A, Yoshida A, Takahashi K, Nishida H, Lassak K, Taka H, Mineki R, Fujimura T, Kosono S, Nishiyama C, Masui R, Kuramitsu S, Albers SV, Kuzuyama T, Nishiyama M
  Title
Lysine and arginine biosyntheses mediated by a common carrier protein in Sulfolobus.
  Journal
Nat Chem Biol 9:277-83 (2013)
DOI:10.1038/nchembio.1200
  Sequence
[sai:Saci_0756]
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