KEGG   ORTHOLOGY: K05867
Entry
K05867                      KO                                     
Symbol
CDC25C
Name
M-phase inducer phosphatase 3 [EC:3.1.3.48]
Pathway
map04110  Cell cycle
map04114  Oocyte meiosis
map04914  Progesterone-mediated oocyte maturation
map05170  Human immunodeficiency virus 1 infection
map05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K05867  CDC25C; M-phase inducer phosphatase 3
   04114 Oocyte meiosis
    K05867  CDC25C; M-phase inducer phosphatase 3
 09150 Organismal Systems
  09152 Endocrine system
   04914 Progesterone-mediated oocyte maturation
    K05867  CDC25C; M-phase inducer phosphatase 3
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    K05867  CDC25C; M-phase inducer phosphatase 3
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K05867  CDC25C; M-phase inducer phosphatase 3
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K05867  CDC25C; M-phase inducer phosphatase 3
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K05867  CDC25C; M-phase inducer phosphatase 3
   03400 DNA repair and recombination proteins
    K05867  CDC25C; M-phase inducer phosphatase 3
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     K05867  CDC25C; M-phase inducer phosphatase 3
Protein phosphatases and associated proteins [BR:ko01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K05867  CDC25C; M-phase inducer phosphatase 3
 Protein tyrosine phosphatases (PTPs)
  Class III PTPs
   CDC25s
    K05867  CDC25C; M-phase inducer phosphatase 3
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Centrosome formation proteins
   Centrosome duplication proteins
    Other centrosome duplication proteins
     K05867  CDC25C; M-phase inducer phosphatase 3
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic type
  Check point factors
   Other check point factors
    K05867  CDC25C; M-phase inducer phosphatase 3
Other DBs
GO: 0004725
Genes
HSA: 995(CDC25C)
PTR: 746151(CDC25C)
PPS: 100990018(CDC25C)
GGO: 101150213(CDC25C)
PON: 100451443(CDC25C)
PPYG: 129037036(CDC25C)
NLE: 100588617(CDC25C)
HMH: 116471552(CDC25C)
SSYN: 129486336(CDC25C)
MCC: 714115(CDC25C)
MCF: 101866661(CDC25C)
MTHB: 126957362
MNI: 105467080(CDC25C)
CSAB: 103244613(CDC25C)
CATY: 105599837(CDC25C)
PANU: 101017717(CDC25C)
TGE: 112625735(CDC25C)
MLEU: 105551840(CDC25C)
RRO: 104681726(CDC25C)
RBB: 108541696(CDC25C)
TFN: 117065805(CDC25C)
PTEH: 111528664(CDC25C)
CANG: 105506977(CDC25C)
CJC: 100387914(CDC25C)
SBQ: 101041558(CDC25C)
CIMI: 108284257(CDC25C) 108297658
ANAN: 105733958(CDC25C)
CSYR: 103261706(CDC25C)
MMUR: 105862589(CDC25C)
LCAT: 123637817(CDC25C)
PCOQ: 105812033(CDC25C)
OGA: 100964410(CDC25C)
MMU: 12532(Cdc25c)
MCAL: 110284647(Cdc25c)
MPAH: 110333485(Cdc25c)
RNO: 307511(Cdc25c)
MCOC: 116086979(Cdc25c)
ANU: 117719745(Cdc25c)
MUN: 110558466(Cdc25c)
CGE: 100773417(Cdc25c)
MAUA: 101828859(Cdc25c)
PROB: 127235110(Cdc25c)
PLEU: 114705113(Cdc25c)
MFOT: 126497036
AAMP: 119814812(Cdc25c)
NGI: 103735158(Cdc25c)
HGL: 101712931(Cdc25c)
CCAN: 109700186(Cdc25c)
DORD: 105988647(Cdc25c)
DSP: 122118179(Cdc25c)
PLOP: 125339885(Cdc25c)
NCAR: 124987233
MMMA: 107141294(Cdc25c)
OCU: 100343637
OPI: 101519435(CDC25C)
TUP: 102499060(CDC25C)
GVR: 103590544(CDC25C)
CFA: 610456(CDC25C)
CLUD: 112649793(CDC25C)
VVP: 112921903(CDC25C)
VLG: 121494351(CDC25C)
NPO: 129495050(CDC25C)
AML: 100482691(CDC25C)
UMR: 103663783(CDC25C)
UAH: 113261495(CDC25C)
UAR: 123790307(CDC25C)
LLV: 125100775
MPUF: 101678023(CDC25C)
MNP: 132028550(CDC25C)
MLK: 131832093(CDC25C)
NVS: 122891205(CDC25C)
ORO: 101367041(CDC25C)
EJU: 114209504(CDC25C)
ZCA: 113929304(CDC25C)
MLX: 118016681(CDC25C)
NSU: 110591218(CDC25C)
LWW: 102749369(CDC25C)
FCA: 101086942(CDC25C)
PYU: 121010761(CDC25C)
PCOO: 112860266(CDC25C)
PBG: 122487894(CDC25C)
PVIV: 125173403(CDC25C)
LRUF: 124516125
PTG: 102968740(CDC25C)
PPAD: 109252124(CDC25C)
PUC: 125935547
AJU: 106967966
HHV: 120220748(CDC25C)
BTA: 507731(CDC25C)
BOM: 102287313(CDC25C)
BIU: 109562060(CDC25C)
BBUB: 102401152(CDC25C)
BBIS: 104991822(CDC25C)
CHX: 102187214(CDC25C)
OAS: 101110327(CDC25C)
BTAX: 128051380(CDC25C)
ODA: 120863610(CDC25C)
CCAD: 122439872(CDC25C)
MBEZ: 129558754(CDC25C)
SSC: 100144474(CDC25C)
CFR: 102516690(CDC25C)
CBAI: 105082163(CDC25C)
CDK: 105090655(CDC25C)
VPC: 102534342(CDC25C)
BACU: 103014243(CDC25C)
BMUS: 118892864(CDC25C)
LVE: 103088476(CDC25C)
OOR: 101276884(CDC25C)
DLE: 111182493(CDC25C)
PCAD: 102978115(CDC25C)
PSIU: 116752324(CDC25C)
NASI: 112404397(CDC25C)
ECB: 100062352(CDC25C)
EPZ: 103551352(CDC25C)
EAI: 106839210(CDC25C)
MYB: 102262547(CDC25C)
MYD: 102761242(CDC25C)
MMYO: 118658931(CDC25C)
MLF: 102419273(CDC25C)
PKL: 118711716(CDC25C)
EFUS: 103289927(CDC25C)
MNA: 107530121(CDC25C)
DRO: 112318157(CDC25C)
SHON: 118997533(CDC25C)
AJM: 119051049(CDC25C)
PDIC: 114509524(CDC25C)
PHAS: 123809892(CDC25C)
MMF: 118615143(CDC25C)
PPAM: 129066655(CDC25C)
HAI: 109392993(CDC25C)
RFQ: 117016695(CDC25C)
PALE: 102894193(CDC25C)
PGIG: 120581351(CDC25C)
PVP: 105293614(CDC25C)
RAY: 107518727(CDC25C)
MJV: 108385295(CDC25C)
TOD: 119243428(CDC25C)
SARA: 101545153(CDC25C)
SETR: 126027034(CDC25C)
LAV: 100670954(CDC25C)
TMU: 101342935
ETF: 101645781(CDC25C)
DNM: 101412555(CDC25C)
MDO: 100014440 100025023(CDC25C)
GAS: 123233861(CDC25C)
SHR: 100924438(CDC25C)
AFZ: 127549958
PCW: 110220848(CDC25C)
TVP: 118844181(CDC25C)
AAM: 106487224(CDC25C)
AROW: 112964852(CDC25C)
NPD: 112952895(CDC25C)
TGT: 104571367(CDC25C)
DNE: 112994068(CDC25C)
SCAM: 104140178(CDC25C)
ASN: 102384314(CDC25C)
AMJ: 102572255(CDC25C)
CPOO: 109310259(CDC25C)
GGN: 109289807(CDC25C)
PSS: 102456953(CDC25C)
CMY: 102945797(CDC25C)
CCAY: 125641116(CDC25C)
DCC: 119860328(CDC25C)
CPIC: 101952003(CDC25C)
TST: 117882039(CDC25C)
CABI: 116828122(CDC25C)
MRV: 120370938(CDC25C)
ACS: 100565034(cdc25c)
ASAO: 132769076(CDC25C)
PVT: 110077149(CDC25C)
SUND: 121922253(CDC25C)
PBI: 103051692(CDC25C)
PMUR: 107289189(CDC25C) 107299702
CTIG: 120304014(CDC25C)
TSR: 106545415(CDC25C)
APRI: 131190211(CDC25C)
PTEX: 113449923(CDC25C)
NSS: 113415708(CDC25C)
VKO: 123034167(CDC25C)
PMUA: 114591472(CDC25C)
PRAF: 128408096(CDC25C)
ZVI: 118081558(CDC25C)
HCG: 128342734(CDC25C)
GJA: 107107149
STOW: 125429658(CDC25C)
EMC: 129328612(CDC25C)
XLA: 100337563(cdc25c.S) 398119(cdc25c.L)
XTR: 100124300(cdc25c)
NPR: 108797600(CDC25C)
RTEM: 120932164(CDC25C)
BBUF: 120978692(CDC25C)
BGAR: 122928120(CDC25C)
CHAR: 105892470
SASA: 106563618
STRU: 115204425
OTW: 112231192
OMY: 110510100
OGO: 124007279
ONE: 115101434(cdc25c)
OKI: 109874256(cdc25c)
OKE: 118385009
SALP: 111964299
SNH: 120021486
CCLU: 121541254
ELS: 105010884(cdc25c)
SFM: 108934112(cdc25c)
PKI: 111850200(cdc25c)
AANG: 118222606
PSPA: 121323933
PSEX: 120542019
LCM: 102356985(CDC25C)
CMK: 103177381
CPLA: 122556870
HOC: 132823323
LERI: 129701462
AGRG: 126749066
PPYR: 116164584
DSV: 119457815
RMP: 119175769
ABRU: 129975049
MCAF: 127702014
LJP: 135466331
 » show all
Reference
PMID:2195549
  Authors
Sadhu K, Reed SI, Richardson H, Russell P
  Title
Human homolog of fission yeast cdc25 mitotic inducer is predominantly expressed in G2.
  Journal
Proc Natl Acad Sci U S A 87:5139-43 (1990)
DOI:10.1073/pnas.87.13.5139
  Sequence
[hsa:995]
Reference
PMID:8119945
  Authors
Strausfeld U, Fernandez A, Capony JP, Girard F, Lautredou N, Derancourt J, Labbe JC, Lamb NJ
  Title
Activation of p34cdc2 protein kinase by microinjection of human cdc25C into mammalian cells. Requirement for prior phosphorylation of cdc25C by p34cdc2 on sites phosphorylated at mitosis.
  Journal
J Biol Chem 269:5989-6000 (1994)
  Sequence
[hsa:995]
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