Entry
Symbol
YPS1_2
Name
Pathway
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09130 Environmental Information Processing
09132 Signal transduction
04011 MAPK signaling pathway - yeast
K06009 YPS1_2; yapsin 1/2
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors
K06009 YPS1_2; yapsin 1/2
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts
K06009 YPS1_2; yapsin 1/2
09183 Protein families: signaling and cellular processes
00537 Glycosylphosphatidylinositol (GPI)-anchored proteins
K06009 YPS1_2; yapsin 1/2
Enzymes [BR:ko01000 ]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.41 yapsin 1
K06009 YPS1_2; yapsin 1/2
Peptidases and inhibitors [BR:ko01002 ]
Aspartic peptidases
Family A1: pepsin family
K06009 YPS1_2; yapsin 1/2
Chaperones and folding catalysts [BR:ko03110 ]
Intramolecular chaperones
Other peptidases
K06009 YPS1_2; yapsin 1/2
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:ko00537 ]
Enzymes
K06009 YPS1_2; yapsin 1/2
BRITE hierarchy
Genes
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Taxonomy UniProt
Reference
Authors
Olsen V, Guruprasad K, Cawley NX, Chen HC, Blundell TL, Loh YP
Title
Cleavage efficiency of the novel aspartic protease yapsin 1 (Yap3p) enhanced for substrates with arginine residues flanking the P1 site: correlation with electronegative active-site pockets predicted by molecular modeling.
Journal
Reference
Authors
Copley KS, Alm SM, Schooley DA, Courchesne WE
Title
Expression, processing and secretion of a proteolytically-sensitive insect diuretic hormone by Saccharomyces cerevisiae requires the use of a yeast strain lacking genes encoding the Yap3 and Mkc7 endoproteases found in the secretory pathway.
Journal
Reference
Authors
Krysan DJ, Ting EL, Abeijon C, Kroos L, Fuller RS
Title
Yapsins are a family of aspartyl proteases required for cell wall integrity in Saccharomyces cerevisiae.
Journal
Sequence
LinkDB
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