| Entry |
|
| Symbol |
NMNAT
|
| Name |
|
| Pathway |
| map00760 | Nicotinate and nicotinamide metabolism |
|
| Module |
| M00115 | NAD biosynthesis, aspartate => quinolinate => NAD |
| M00912 | NAD biosynthesis, tryptophan => quinolinate => NAD |
|
| Reaction |
| R00137 | ATP:nicotinamide-nucleotide adenylyltransferase |
| R03005 | ATP:nicotinamide-nucleotide adenylyltransferase |
|
| Disease |
| H00837 | Leber congenital amaurosis |
| H02950 | Spondyloepiphyseal dysplasia, sensorineural hearing loss, impaired intellectual development, and Leber congenital amaurosis |
|
| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
K06210 NMNAT; nicotinamide mononucleotide adenylyltransferase
Enzymes [BR:ko01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.1 nicotinamide-nucleotide adenylyltransferase
K06210 NMNAT; nicotinamide mononucleotide adenylyltransferase
2.7.7.18 nicotinate-nucleotide adenylyltransferase
K06210 NMNAT; nicotinamide mononucleotide adenylyltransferase
|
| Other DBs |
|
| Genes |
» show all
|
| Reference |
|
| Authors |
Emanuelli M, Carnevali F, Saccucci F, Pierella F, Amici A, Raffaelli N, Magni G |
| Title |
Molecular cloning, chromosomal localization, tissue mRNA levels, bacterial expression, and enzymatic properties of human NMN adenylyltransferase. |
| Journal |
|
| Sequence |
|
| Reference |
|
| Authors |
Lau C, Niere M, Ziegler M |
| Title |
The NMN/NaMN adenylyltransferase (NMNAT) protein family. |
| Journal |
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| LinkDB |
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