KEGG   ORTHOLOGY: K06633
Entry
K06633                      KO                                     
Symbol
PKMYT
Name
membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
Pathway
map04110  Cell cycle
map04114  Oocyte meiosis
map04914  Progesterone-mediated oocyte maturation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K06633  PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
   04114 Oocyte meiosis
    K06633  PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
 09150 Organismal Systems
  09152 Endocrine system
   04914 Progesterone-mediated oocyte maturation
    K06633  PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K06633  PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
   01009 Protein phosphatases and associated proteins
    K06633  PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K06633  PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
Protein kinases [BR:ko01001]
 Serine/threonine kinases: Other
  WEE family
   K06633  PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
Protein phosphatases and associated proteins [BR:ko01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K06633  PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
Genes
HSA: 9088(PKMYT1)
PTR: 467880(PKMYT1)
PPS: 100991081(PKMYT1)
PON: 100460825(PKMYT1)
NLE: 100585390(PKMYT1)
HMH: 116462661(PKMYT1)
MCC: 699350(PKMYT1)
MCF: 102137464(PKMYT1)
MTHB: 126944791
MNI: 105467897(PKMYT1)
CSAB: 103227033(PKMYT1)
CATY: 105572051(PKMYT1)
PANU: 101012253(PKMYT1)
TGE: 112613993(PKMYT1)
MLEU: 105541547(PKMYT1)
RRO: 104672324(PKMYT1)
RBB: 108523343(PKMYT1)
TFN: 117097766(PKMYT1)
PTEH: 111551697(PKMYT1)
CANG: 105517631(PKMYT1)
CJC: 100411457(PKMYT1)
SBQ: 101039582(PKMYT1)
CIMI: 108290967(PKMYT1)
CSYR: 103252036(PKMYT1)
MMUR: 105859742(PKMYT1)
LCAT: 123632281(PKMYT1)
PCOQ: 105813142(PKMYT1)
OGA: 100963735(PKMYT1)
MMU: 268930(Pkmyt1)
MCAL: 110312532(Pkmyt1)
MPAH: 110338115(Pkmyt1)
RNO: 287101(Pkmyt1)
MCOC: 116077615(Pkmyt1)
ANU: 117710892(Pkmyt1)
MUN: 110545930(Pkmyt1)
CGE: 100771831(Pkmyt1)
MAUA: 101836834(Pkmyt1)
PROB: 127219591(Pkmyt1)
PLEU: 114680782(Pkmyt1)
MORG: 121463677(Pkmyt1)
MFOT: 126498208
AAMP: 119812278(Pkmyt1)
NGI: 103744069(Pkmyt1)
HGL: 101721451(Pkmyt1)
CPOC: 100714526(Pkmyt1)
CCAN: 109691712(Pkmyt1)
DORD: 105982046(Pkmyt1)
DSP: 122123840(Pkmyt1)
PLOP: 125340393(Pkmyt1)
NCAR: 124970177
MMMA: 107146691(Pkmyt1)
OCU: 100341906
OPI: 101534381(PKMYT1)
TUP: 102501209(PKMYT1)
GVR: 103585356(PKMYT1)
CFA: 490050(PKMYT1)
CLUD: 112640499(PKMYT1)
VVP: 112908993(PKMYT1)
VLG: 121488128(PKMYT1) 121496974
NPO: 129519685(PKMYT1)
AML: 100475442(PKMYT1)
UMR: 103668503(PKMYT1)
UAH: 113245420(PKMYT1)
UAR: 123783581(PKMYT1)
ELK: 111156072
LLV: 125090682
MPUF: 101675076(PKMYT1)
MNP: 132026989(PKMYT1)
MLK: 131819513(PKMYT1)
NVS: 122895366(PKMYT1)
ORO: 101381375(PKMYT1)
EJU: 114215605(PKMYT1)
ZCA: 113932880(PKMYT1)
MLX: 118021743(PKMYT1)
NSU: 110587890(PKMYT1)
LWW: 102744453(PKMYT1)
FCA: 101098425(PKMYT1)
PYU: 121019645(PKMYT1)
PCOO: 112853185(PKMYT1)
PBG: 122471781(PKMYT1)
PVIV: 125154393(PKMYT1)
LRUF: 124517777
PTG: 102963833(PKMYT1)
PPAD: 109278197
PUC: 125927209
AJU: 106978727
HHV: 120241525(PKMYT1)
BTA: 522613(PKMYT1)
BOM: 102287359(PKMYT1)
BIU: 109578714(PKMYT1)
BBUB: 102411391(PKMYT1)
BBIS: 104988879(PKMYT1)
CHX: 102176487(PKMYT1)
OAS: 101119784(PKMYT1)
BTAX: 128064176(PKMYT1)
ODA: 120873903(PKMYT1)
CCAD: 122433204(PKMYT1)
MBEZ: 129545295(PKMYT1)
SSC: 100286809(PKMYT1)
CFR: 102521962(PKMYT1)
CBAI: 105064827(PKMYT1)
CDK: 105099691(PKMYT1)
VPC: 102529486(PKMYT1)
BACU: 103006686(PKMYT1)
BMUS: 118881517(PKMYT1)
LVE: 103079390(PKMYT1)
OOR: 101289480(PKMYT1)
DLE: 111185212(PKMYT1)
PCAD: 102973951(PKMYT1)
PSIU: 116740532(PKMYT1)
NASI: 112409427(PKMYT1)
ECB: 100068871(PKMYT1)
EPZ: 103551624(PKMYT1)
EAI: 106826041(PKMYT1)
MYB: 102239469(PKMYT1)
MYD: 102772635(PKMYT1)
MMYO: 118656846(PKMYT1)
MLF: 102436053(PKMYT1)
PKL: 118703160(PKMYT1)
EFUS: 103286180(PKMYT1)
MNA: 107535809(PKMYT1)
DRO: 112298329(PKMYT1)
SHON: 118985094(PKMYT1)
AJM: 119063428(PKMYT1)
PDIC: 114495276(PKMYT1)
PHAS: 123807138(PKMYT1)
MMF: 118641905(PKMYT1)
PPAM: 129083627(PKMYT1)
HAI: 109377832(PKMYT1)
RFQ: 117019622(PKMYT1)
PALE: 102894398(PKMYT1)
PGIG: 120620293(PKMYT1)
PVP: 105303130(PKMYT1)
RAY: 107498788(PKMYT1)
MJV: 108394455(PKMYT1)
TOD: 119242005(PKMYT1)
SARA: 101539663(PKMYT1)
SETR: 126001273(PKMYT1)
LAV: 100657179(PKMYT1)
TMU: 101361251
ETF: 101662444(PKMYT1)
DNM: 101445754(PKMYT1)
MDO: 100618653(PKMYT1)
GAS: 123231533(PKMYT1)
SHR: 100915144(PKMYT1)
AFZ: 127542570
PCW: 110214562(PKMYT1)
OAA: 100088227(PKMYT1)
LMUT: 125687641(PKMYT1)
AROW: 112969568(PKMYT1)
ASN: 102372270(PKMYT1)
AMJ: 102573832(PKMYT1)
PSS: 102458496(PKMYT1)
CMY: 102948305(PKMYT1)
CCAY: 125639136(PKMYT1)
DCC: 119856766(PKMYT1)
CPIC: 101938167(PKMYT1)
CABI: 116840200(PKMYT1)
MRV: 120403305(PKMYT1)
ACS: 100561512(pkmyt1)
ASAO: 132777993(PKMYT1)
PVT: 110088382(PKMYT1)
SUND: 121934668(PKMYT1)
PBI: 103051788(PKMYT1)
PMUR: 107282525(PKMYT1) 107296267
CTIG: 120309030(PKMYT1)
TSR: 106555558
PGUT: 117669177(PKMYT1)
APRI: 131198806(PKMYT1)
PTEX: 113443610(PKMYT1)
NSS: 113418592(PKMYT1)
VKO: 123032224(PKMYT1)
PMUA: 114581426(PKMYT1)
PRAF: 128399490(PKMYT1)
ZVI: 118094899(PKMYT1)
HCG: 128329379(PKMYT1)
GJA: 107105462(PKMYT1)
STOW: 125444892(PKMYT1)
EMC: 129340118(PKMYT1)
XLA: 108701724(pkmyt1.L) 379626(pkmyt1.S)
XTR: 100145798(pkmyt1)
NPR: 108803590(PKMYT1)
RTEM: 120942887(PKMYT1)
BBUF: 121007848(PKMYT1)
BGAR: 122922428(PKMYT1)
MUO: 115474673(PKMYT1)
GSH: 117361483(PKMYT1)
DRE: 100049158(pkmyt1)
SRX: 107708287(pkmyt1)
SANH: 107674749(pkmyt1)
SGH: 107579468(pkmyt1)
CCAR: 109048014(pkmyt1)
CAUA: 113056284(pkmyt1)
CGIB: 128025681
PTET: 122355828(pkmyt1)
LROH: 127174497(pkmyt1)
OMC: 131550861(pkmyt1)
PPRM: 120488681(pkmyt1)
RKG: 130087364(pkmyt1)
MAMB: 125251695(pkmyt1)
CIDE: 127523950
MASI: 127423001 127427113
TROS: 130569482(pkmyt1)
TDW: 130438670(pkmyt1)
MANU: 129420841(pkmyt1)
IPU: 108273928
IFU: 128617134(pkmyt1)
PHYP: 113547506(pkmyt1)
SMEO: 124389240(pkmyt1)
TFD: 113650648(pkmyt1)
TVC: 132841483(pkmyt1)
AMEX: 103038604(pkmyt1)
CMAO: 118808908(pkmyt1)
EEE: 113576838(pkmyt1)
CHAR: 105894011(pkmyt1)
TRU: 101068446(pkmyt1)
TFS: 130531834(pkmyt1)
TNG: GSTEN00035045G001
LCO: 104926892(pkmyt1)
NCC: 104946783(pkmyt1)
TBEN: 117473612(pkmyt1)
CGOB: 115024290(pkmyt1)
PGEO: 117464945(pkmyt1)
GACU: 117544997(pkmyt1)
EMAC: 134870927(pkmyt1)
ELY: 117247582(pkmyt1)
EFO: 125880836(pkmyt1)
PLEP: 121958581(pkmyt1)
SLUC: 116061207(pkmyt1)
ECRA: 117937293(pkmyt1)
ESP: 116671287(pkmyt1)
PFLV: 114548000(pkmyt1)
GAT: 120819090(pkmyt1)
PPUG: 119212620(pkmyt1)
AFB: 129091401(pkmyt1)
CLUM: 117749026(pkmyt1)
PSWI: 130204072(pkmyt1)
MSAM: 119915512(pkmyt1)
SCHU: 122868145(pkmyt1)
CUD: 121527913(pkmyt1)
ALAT: 119009668(pkmyt1)
MZE: 101479538(pkmyt1)
ONL: 100689891(pkmyt1)
OAU: 116335116(pkmyt1)
OLA: 101170224(pkmyt1)
OML: 112154291(pkmyt1)
CSAI: 133419005(pkmyt1)
XMA: 102234305(pkmyt1)
XCO: 114156935(pkmyt1)
XHE: 116727288(pkmyt1)
PFOR: 103152360(pkmyt1)
PLAI: 106956120(pkmyt1)
PMEI: 106925964(pkmyt1)
GAF: 122823544(pkmyt1)
PPRL: 129377824(pkmyt1)
CVG: 107085564(pkmyt1)
CTUL: 119792255(pkmyt1)
GMU: 124874711(pkmyt1)
NFU: 107387939(pkmyt1)
KMR: 108249748(pkmyt1)
ALIM: 106521384(pkmyt1)
NWH: 119423492(pkmyt1)
AOCE: 111568844(pkmyt1)
CSEM: 103381610(pkmyt1)
POV: 109642806(pkmyt1)
SSEN: 122762348(pkmyt1)
HHIP: 117752742(pkmyt1)
HSP: 118100478(pkmyt1)
SMAU: 118287655(pkmyt1)
LCF: 108890414
SDU: 111219943(pkmyt1)
SLAL: 111652267(pkmyt1)
XGL: 120794281(pkmyt1)
HCQ: 109521433 109527021
SSCV: 125991038
SBIA: 133495706(pkmyt1)
PEE: 133418210(pkmyt1)
PTAO: 133469812(pkmyt1)
BPEC: 110170996(pkmyt1)
MALB: 109973624(pkmyt1)
BSPL: 114846068(pkmyt1)
SJO: 128381394(pkmyt1)
SASA: 106579073(pkmyt1)
STRU: 115162173(pkmyt1)
OTW: 112223869
OMY: 110491759(pkmyt1)
OGO: 124048497(pkmyt1)
ONE: 115106713(pkmyt1)
OKI: 109865887(pkmyt1)
OKE: 118364210(pkmyt1)
SALP: 111978480(pkmyt1)
SNH: 120046389(pkmyt1)
CCLU: 121572166(pkmyt1)
ELS: 105030156(pkmyt1)
SFM: 108919296(pkmyt1)
PKI: 111833119(pkmyt1)
AANG: 118220227(pkmyt1)
PSPA: 121305212(pkmyt1)
ARUT: 117398035 117969548
PSEX: 120536605(pkmyt1)
LCM: 102351877(PKMYT1)
CMK: 103171650(pkmyt1)
PMRN: 116950288(PKMYT1)
LRJ: 133348747(PKMYT1)
BFO: 118425497
BBEL: 109464156 109465338
CIN: 100186587
SCLV: 120347056
SPU: 579505
LPIC: 129263837
APLC: 110985458
AJC: 117124246
SKO: 100376881
DME: Dmel_CG32417(Myt1)
DER: 6544697
DSE: 6610915
DSI: Dsimw501_GD13175(Dsim_GD13175)
DYA: Dyak_GE20537
DAN: 6493316
DSR: 110176254
DPO: 4813485
DPE: 6602787
DMN: 108153232
DWI: 6639388
DGR: 6558127 6566886
DMO: Dmoj_GI11942
DAZ: 108612987
DNV: 108650801
DHE: 111605645
DVI: 6622134
CCAT: 101455103
BOD: 106622866
BDR: 105231441
RZE: 108376878
AOQ: 129242508
TDA: 119670798 119687387
MDE: 101899454
SCAC: 106090911
LCQ: 111683298
LSQ: 119608895
GFS: 119631372
ECOE: 129946003
CLON: 129612880
HIS: 119647854
ACOZ: 120950348
AARA: 120895269
AMER: 121591119
ASTE: 118506562
AFUN: 125761221
AMOU: 128297312
AAG: 5567533
AALB: 109413663
CQU: CpipJ_CPIJ003568
CPII: 120414863
CNS: 116350786
BCOO: 119072072
TCA: 659898
DPA: 109532927
SOY: 115882374
ATD: 109597160
CSET: 123322165
AGB: 108909689
NVL: 108568728
APLN: 108741899
PPYR: 116166042
OTU: 111425434
CCRN: 123302233
BTAB: 109039431
NLU: 111064290
HVI: 124368746
MQU: 128998997
FOC: 113204677
TPAL: 117651911
ZNE: 110833511
CSEC: 111868416
IEL: 124170498
FCD: 110851814
DPX: DAPPUDRAFT_12061 DAPPUDRAFT_323973 DAPPUDRAFT_336067
DMK: 116930720 123466256
DPZ: 124310736
PVM: 113810098 113811803
PJA: 122246158
PCHN: 125045048
HAME: 121855518
PCLA: 123745542
CQD: 128697380
PTRU: 123513940
ESN: 126985137
MNZ: 135211972 135212189
HAZT: 108679637
EAF: 111703985
LSM: 121127536
TCF: 131886634
PPOI: 119108223
DSV: 119433811 119437457 119445132
RSAN: 119404671 119405885 119406171
RMP: 119161966 119180610
VDE: 111250078
VJA: 111259813
TUT: 107359046
DPTE: 113794861
DFR: 124494117
CSCU: 111634334
PTEP: 107439195
ABRU: 129969146
UDV: 129234668
SDM: 118194296
LPOL: 106457276
CEL: CELE_F35H8.7(wee-1.1) CELE_Y53C12A.1(wee-1.3)
CBR: CBG_01053(Cbr-wee-1.3) CBG_21908
CRQ: GCK72_003644
NAI: NECAME_09333 NECAME_12987
LOA: LOAG_01883
TSP: Tsp_05938
HRO: HELRODRAFT_62778
LGI: LOTGIDRAFT_140201
PCAN: 112559479
BGT: 106076139
GAE: 121380951
HRF: 124150773
HRJ: 124288637
CRG: 105323275
CANU: 128168111
OED: 125647743 125647746
MYI: 110448417
PMAX: 117335627
MCAF: 127705093
MMER: 123535771
RPHI: 132744398 132752942
DPOL: 127846529
OBI: 106875680
OSN: 115213290
LAK: 106171577
NVE: 5500253
EPA: 110247937
ATEN: 116300889
ADF: 107333784
AMIL: 114977329
PDAM: 113683051
SPIS: 111341918
DGT: 114518385
XEN: 124452738
HMG: 100197452
TAD: TRIADDRAFT_51686
AQU: 100633929
ATR: 105420272
PPP: 112285235
CSL: COCSUDRAFT_46694
APRO: F751_3629 F751_6405
OLU: OSTLU_46744
OTA: OT_ostta10g00670
BPG: Bathy11g00350
MIS: MICPUN_108942
CTEN: CANTEDRAFT_112254
WSE: WALSEDRAFT_32795
SRE: PTSG_03206
DDI: DDB_G0291133 DDB_G0291842
DPP: DICPUDRAFT_158867 DICPUDRAFT_29443
DFA: DFA_01400 DFA_07311
ACAN: ACA1_217150
FCY: FRACYDRAFT_180801(MYT1)
TPS: THAPSDRAFT_263755
NGD: NGA_0208500(WEE1)
PIF: PITG_00477
PSOJ: PHYSODRAFT_509250
SPAR: SPRG_19475
TVA: TVAG_2v0266290 TVAG_2v0647870
 » show all
Reference
PMID:10373560
  Authors
Liu F, Rothblum-Oviatt C, Ryan CE, Piwnica-Worms H
  Title
Overproduction of human Myt1 kinase induces a G2 cell cycle delay by interfering with the intracellular trafficking of Cdc2-cyclin B1 complexes.
  Journal
Mol Cell Biol 19:5113-23 (1999)
DOI:10.1128/MCB.19.7.5113
  Sequence
[hsa:9088]
LinkDB

DBGET integrated database retrieval system