KEGG   ORTHOLOGY: K06863
Entry
K06863                      KO                                     
Symbol
purP
Name
5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [EC:6.3.4.23]
Pathway
map00230  Purine metabolism
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Reaction
R06975  formate:5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide ligase (ADP-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K06863  purP; 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase
Enzymes [BR:ko01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.23  formate---phosphoribosylaminoimidazolecarboxamide ligase
     K06863  purP; 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase
Other DBs
COG: COG1759
Genes
VAB: WPS_12340 WPS_12360
PRF: PeribacterA2_0725 PeribacterA2_0726
MJA: MJ_0136
MFE: Mefer_0308
MVU: Metvu_0168
MFS: MFS40622_1004
MIF: Metin_0767
MJH: JH146_0737
MESG: MLAUSG7_1026(purP)
MESA: MLASG1_0751(purP)
MIG: Metig_0553
MMP: MMP1373
MMQ: MmarC5_0205
MMX: MmarC6_1300
MMZ: MmarC7_0618
MMD: GYY_07695(purP)
MMAK: MMKA1_15970(purP)
MMAO: MMOS7_14780(purP)
MMAD: MMJJ_14660
MAE: Maeo_1327
MVN: Mevan_0683
MVO: Mvol_0265
MOK: Metok_0595
METF: CFE53_06120(purP)
MTH: MTH_1201
MMG: MTBMA_c15790(purP)
MWO: MWSIV6_1594(purP)
MTEE: MTTB_02260(purP)
METC: MTCT_1094
METE: tca_01158
METZ: METMT2_1203
METK: FVF72_05615
MTHM: FZP57_07640
MST: Msp_0240
METB: AW729_05985(purP)
MEIS: PXD04_04980
MRU: mru_0595(purP)
MSI: Msm_0506
MEB: Abm4_1385(purP)
MMIL: sm9_0511(purP)
MEYE: TL18_02305(purP)
MOL: YLM1_0256
MARO: MarbSA_08230(purP)
METV: K4897_03040
MEL: Metbo_0324
MEW: MSWAN_2096
METH: MBMB1_0083(purP)
MFC: BRM9_0147(purP)
MFI: DSM1535_1470(purP)
MCUB: MCBB_2033(purP)
MSUB: BK009_10205(purP)
METN: BK008_05830(purP)
METT: CIT01_03875(purP)
METO: CIT02_06600(purP)
MEME: HYG87_05155
MFEG: GCM10025860_03410(purP)
MEER: NKF70_05370
MFV: Mfer_0393
MKA: MK0588
AFU: AF_0113 AF_0256
AFG: AFULGI_00001100 AFULGI_00002440
APO: Arcpr_1226 Arcpr_1231
AVE: Arcve_0590 Arcve_1105
AST: Asulf_00339 Asulf_00414
FPL: Ferp_0934 Ferp_1822
GAC: GACE_1955 GACE_2044
GAH: GAH_00649 GAH_00717
PFU: PF0421 PF1517
PFI: PFC_01190 PFC_06820(purP)
PHO: PH0324(PH0324) PH1348(PH1348)
PAB: PAB0547 PAB1272
PYN: PNA2_0941 PNA2_1924
PYA: PYCH_06270 PYCH_10750 PYCH_16070
PYS: Py04_0506 Py04_1238
PYC: TQ32_03685 TQ32_10365
TKO: TK0196 TK0203 TK0431
TGA: TGAM_0751(purP) TGAM_0757 TGAM_1267
TSI: TSIB_0049 TSIB_0059
TBA: TERMP_02032 TERMP_02040
THE: GQS_02000(purP) GQS_05740(purP) GQS_05765
THA: TAM4_1003 TAM4_813
THM: CL1_0040 CL1_0780 CL1_0784
TLT: OCC_05274 OCC_06571 OCC_06656
TNU: BD01_0510 BD01_1742 BD01_1747
TEU: TEU_00655 TEU_00705 TEU_09520
TGY: X802_06580 X802_06610 X802_10035
THV: ADU37_CDS22240 ADU37_CDS22310 ADU37_CDS22690
TCH: CHITON_1151 CHITON_1566
TPEP: A0127_02245 A0127_02990 A0127_03015
TPIE: A7C91_05460 A7C91_05480 A7C91_09085
TCE: A3L02_01430 A3L02_01515 A3L02_01970
TBS: A3L01_00110 A3L01_00130
THH: CDI07_00150 CDI07_00175
TSL: A3L11_03840 A3L11_03860
TTD: A3L14_01400 A3L14_01430 A3L14_05520
TPRF: A3L09_06380 A3L09_08495 A3L09_08525
TRL: A3L10_09820 A3L10_09840
TPAF: A3L08_03260 A3L08_03280 A3L08_06910
THY: A3L12_03075 A3L12_03145 A3L12_03165
TIC: FH039_02150 FH039_02230 FH039_06480
TCQ: TIRI35C_0238(purP) TIRI35C_0244(purP) TIRI35C_0997
THEM: FPV09_02900 FPV09_07110 FPV09_07135
THEI: K1720_03315 K1720_03365
PPAC: PAP_00555 PAP_00655
MBA: Mbar_A0288 Mbar_A1334
MBY: MSBRM_0231 MSBRM_2665
MBW: MSBRW_0708 MSBRW_3391
MBAR: MSBR2_2150 MSBR2_2623
MBAK: MSBR3_2218 MSBR3_2802
MAC: MA_0206 MA_3689
MMA: MM_0593 MM_1493 MM_2913
MMAZ: MmTuc01_0600 MmTuc01_1548 MmTuc01_2988
MMJ: MSMAS_0716 MSMAS_1802 MSMAS_3175
MMAC: MSMAC_0717 MSMAC_1314 MSMAC_3195
MVC: MSVAZ_0238 MSVAZ_0647
MEK: MSKOL_0231 MSKOL_0625
MLS: MSLAZ_0127 MSLAZ_2268
METM: MSMTP_0909 MSMTP_3081
MEF: MSWH1_0142 MSWH1_2406
MEQ: MSWHS_0140 MSWHS_2641
MSJ: MSSAC_0179 MSSAC_3519
MSZ: MSSIH_0165 MSSIH_3038
MSW: MSSIT_0169 MSSIT_3096
MTHR: MSTHT_1985 MSTHT_2423
MTHE: MSTHC_0859 MSTHC_1299
MHOR: MSHOH_0831 MSHOH_2312 MSHOH_3913
MFZ: AOB57_003310 AOB57_009245
MBU: Mbur_1029(purP) Mbur_1626(purP)
MMET: MCMEM_1511 MCMEM_2123
MELO: J7W08_06365 J7W08_09580
MMH: Mmah_0026 Mmah_1404
MHAZ: BHR79_03335 BHR79_06655
MPOT: BKM01_02900 BKM01_10575
MEV: Metev_0086 Metev_0565
MZH: Mzhil_0081 Mzhil_0477
MPY: Mpsy_0967(purP) Mpsy_1916
MZI: HWN40_03700 HWN40_12625
MMAV: RE476_06515 RE476_10895
MSEB: RE474_01995 RE474_07470
MHZ: Metho_0136 Metho_0550
MEHF: MmiHf6_07840 MmiHf6_15440
MEES: MmiEs2_00040 MmiEs2_03160
MTP: Mthe_0184 Mthe_1099
MCJ: MCON_1268 MCON_3207
MHI: Mhar_0372 Mhar_0580
MPD: MCP_2462(purP-1) MCP_2481(purP-2) MCP_2482(purP-3)
MEZ: Mtc_2399(purP)
RCI: RCIX2374(purP)
MJK: N2V74_06085
MEAM: MU439_05700 MU439_05705
MEAE: QEN48_04455 QEN48_04460
TAR: TALC_00174 TALC_01295
MAX: MMALV_01620 MMALV_13860
MER: MMINT_01670(purP) MMINT_02910
MEAR: Mpt1_c09180(purP1) Mpt1_c13110(purP2)
MEUZ: KRP56_00920 KRP56_06745
MARC: AR505_0257 AR505_1667
SMR: Smar_1525
IHO: Igni_0442 Igni_0943
IIS: EYM_01025 EYM_07900
IPC: IPA_00050 IPA_03630
DKA: DKAM_0529 DKAM_0531
DFD: Desfe_0493 Desfe_0495
IAG: Igag_0271 Igag_0273
PFM: Pyrfu_0237 Pyrfu_0911
PDL: Pyrde_0289 Pyrde_0749
PABI: PABY_04650 PABY_24630
STO: STK_02890(purP) STK_02900(purP)
SOH: D1869_00985 D1869_00990
SSO: SSO0239 SSO0241
SOL: Ssol_1218 Ssol_1219
SSOA: SULA_1258 SULA_1259
SSOL: SULB_1259 SULB_1260
SSOF: SULC_1257 SULC_1258
SSHI: J5U23_00015 J5U23_00016
SCAS: SACC_01530 SACC_01540
SAI: Saci_0707 Saci_0708
SACN: SacN8_03410(purP) SacN8_03415
SACR: SacRon12I_03400(purP) SacRon12I_03405
SACS: SUSAZ_03180 SUSAZ_03185
SIS: LS215_2006 LS215_2007
SIA: M1425_1897 M1425_1898
SIM: M1627_1974 M1627_1975
SID: M164_1904 M164_1905
SIY: YG5714_1973 YG5714_1974
SIN: YN1551_0946 YN1551_0947
SII: LD85_2118 LD85_2119
SIH: SiH_1834 SiH_1836
SIR: SiRe_1754 SiRe_1756
SIC: SiL_1747 SiL_1748
SULA: BFU36_04630 BFU36_04635
SULE: GFS03_10400 GFS03_10405
SULO: GFS33_02215 GFS33_02220
SULL: EWF20_02450 EWF20_02455
MSE: Msed_0016 Msed_0017
MEMJ: MJ1HA_0016 MJ1HA_0017
MCN: Mcup_0016 Mcup_0017
MHK: DFR87_07050 DFR87_07055
MPRU: DFR88_06610 DFR88_06615
MTEN: GWK48_05105 GWK48_05110
MJN: MjAS7_0603 MjAS7_0604
AHO: Ahos_0764 Ahos_0765
AMAN: B6F84_07270 B6F84_07275
ABRI: DFR85_07650 DFR85_07655
ASUL: DFR86_06330 DFR86_06335
AAMB: D1866_11640 D1866_11645
ACIH: HS5_21380 HS5_21390
SACD: HS1genome_0014 HS1genome_0015
SAZO: D1868_01780 D1868_01785
CSTY: KN1_18510 KN1_18520
STEP: IC006_1811 IC006_1812
SMET: RQ359_000029 RQ359_000030
PAI: PAE0604 PAE0608
PIS: Pisl_0094 Pisl_0095
PCL: Pcal_0449 Pcal_2033
PAS: Pars_2262 Pars_2265
PYR: P186_2114 P186_2117
POG: Pogu_2597 Pogu_2600
TNE: Tneu_1918 Tneu_1919
PYW: PYWP30_02163 PYWP30_02165
CMA: Cmaq_0021 Cmaq_0022
TTN: TTX_0542 TTX_0543
TUZ: TUZN_0184 TUZN_0185
VDI: Vdis_0677 Vdis_0678
VMO: VMUT_1944 VMUT_1945
VSO: Vsou_00990 Vsou_01000
FFO: FFONT_0566 FFONT_0568
KCR: Kcr_0400 Kcr_0401
NMR: Nmar_0770 Nmar_0872
NIR: NSED_04285 NSED_04890(purP)
NKR: NKOR_04240 NKOR_04920(purP)
NID: NPIRD3C_1324(purP) NPIRD3C_1455
NIN: NADRNF5_1179(purP) NADRNF5_1308
NIW: Nisw_00370 Nisw_00920
NCL: C5F47_04390 C5F47_05060
NOX: C5F49_04300 C5F49_04985
NUE: C5F50_05790 C5F50_06470
NIP: NsoK4_03660 NsoK4_04330
NZT: NZOSNM25_001050 NZOSNM25_001167
NCT: NMSP_0725(purP_1) NMSP_0856(purP_2)
NIC: DSQ20_04355
NGA: Ngar_c02760(purP1) Ngar_c27450(purP2)
NVN: NVIE_014230(purP1) NVIE_015540(purP2)
NEV: NTE_00824 NTE_02840
TAA: NMY3_02655 NMY3_03715
NFN: NFRAN_0263(purP) NFRAN_1004(purP)
NCV: NCAV_0743(purP) NCAV_1281(purP)
NDV: NDEV_1117(purP) NDEV_1244(purP)
CSY: CENSYa_0242 CENSYa_0907
CSU: CSUB_C0852 CSUB_C0853
NBV: T478_0670 T478_0775
TAH: SU86_001715 SU86_002275
NIU: DSQ19_04515 DSQ19_05280
NCK: QVH35_08620
CCAI: NAS2_1505 NAS2_1506
BARB: AOA66_0604(purP)
FLT: Sv326_1155 Sv326_1156
 » show all
Reference
PMID:15623504
  Authors
Ownby K, Xu H, White RH
  Title
A Methanocaldococcus jannaschii archaeal signature gene encodes for a 5-formaminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate synthetase. A new enzyme in purine biosynthesis.
  Journal
J Biol Chem 280:10881-7 (2005)
DOI:10.1074/jbc.M413937200
  Sequence
[mja:MJ_0136]
Reference
PMID:18069798
  Authors
Zhang Y, White RH, Ealick SE
  Title
Crystal structure and function of 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase from Methanocaldococcus jannaschii.
  Journal
Biochemistry 47:205-17 (2008)
DOI:10.1021/bi701406g
  Sequence
[mja:MJ_0136] [pfu:PF1517]
LinkDB

DBGET integrated database retrieval system