ORTHOLOGY: K07193
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Entry
K07193 KO
Symbol
SH2B, APS
Name
SH2B adapter protein 2
Pathway
map04722
Neurotrophin signaling pathway
map04910
Insulin signaling pathway
Brite
KEGG Orthology (KO) [BR:
ko00001
]
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
K07193 SH2B, APS; SH2B adapter protein 2
09156 Nervous system
04722 Neurotrophin signaling pathway
K07193 SH2B, APS; SH2B adapter protein 2
BRITE hierarchy
Other DBs
GO:
0005070
0005068
Genes
HSA:
10603
(SH2B2)
PTR:
741557
(SH2B2)
PPS:
100987922
117981055
(SH2B2)
GGO:
101129445
129534749
(SH2B2)
PON:
100443516
(SH2B2)
PPYG:
129041174
(SH2B2)
NLE:
100598632
(SH2B2)
HMH:
116810979
(SH2B2)
SSYN:
129489688
(SH2B2)
MCC:
714861
(SH2B2)
MCF:
102121730
(SH2B2)
MTHB:
126950350
MNI:
105492750
(SH2B2)
CSAB:
103246680
(SH2B2)
CATY:
105593393
(SH2B2)
PANU:
101025701
(SH2B2)
TGE:
112620902
(SH2B2)
MLEU:
105543357
(SH2B2)
RRO:
104681196
(SH2B2)
RBB:
108518901
(SH2B2)
TFN:
117072409
(SH2B2)
PTEH:
111527920
(SH2B2)
CANG:
105503725
(SH2B2)
CJC:
100388274
(SH2B2)
SBQ:
101032970
CIMI:
108307945
(SH2B2)
ANAN:
105714994
(SH2B2)
CSYR:
103259073
(SH2B2)
MMUR:
105868276
(SH2B2)
LCAT:
123632577
(SH2B2)
PCOQ:
105807014
105826038
(SH2B2)
OGA:
100964578
(SH2B2)
MMU:
23921
(Sh2b2)
MCAL:
110294826
(Sh2b2)
MPAH:
110312818
(Sh2b2)
RNO:
114203
(Sh2b2)
MCOC:
116068564
(Sh2b2)
ANU:
117697961
(Sh2b2)
MUN:
110557240
(Sh2b2)
CGE:
100767263
(Sh2b2)
MAUA:
101826206
(Sh2b2)
PROB:
127236969
(Sh2b2)
PLEU:
114710326
(Sh2b2)
MORG:
121446127
(Sh2b2)
MFOT:
126491928
AAMP:
119825332
(Sh2b2)
NGI:
103733485
(Sh2b2)
HGL:
101724022
(Sh2b2)
CPOC:
100731290
(Sh2b2)
CCAN:
109681591
(Sh2b2)
DORD:
105997315
(Sh2b2)
DSP:
122113522
(Sh2b2)
PLOP:
125368001
(Sh2b2)
NCAR:
124970494
MMMA:
107146595
(Sh2b2)
OCU:
100358497
OPI:
101536336
(SH2B2)
TUP:
102470319
(SH2B2)
GVR:
103610441
(SH2B2)
CFA:
489820
(SH2B2)
CLUD:
112646190
(SH2B2)
VVP:
112935733
(SH2B2)
VLG:
121486265
(SH2B2)
NPO:
129519198
(SH2B2)
AML:
105240494
(SH2B2)
UMR:
103670203
(SH2B2)
UAH:
113267828
(SH2B2)
UAR:
123777286
(SH2B2)
ELK:
111145688
LLV:
125090246
MPUF:
101680301
(SH2B2)
MNP:
132026590
(SH2B2)
MLK:
131819799
(SH2B2)
NVS:
122895733
(SH2B2)
ORO:
101380881
(SH2B2)
EJU:
114214362
(SH2B2)
ZCA:
113933128
(SH2B2)
MLX:
117999452
(SH2B2)
NSU:
110589805
(SH2B2)
FCA:
101090410
(SH2B2)
PYU:
121017448
(SH2B2)
PBG:
122471332
(SH2B2)
PVIV:
125154391
(SH2B2)
LRUF:
124519198
PTG:
102949441
(SH2B2)
PPAD:
109250551
(SH2B2)
PUC:
125928197
AJU:
106980692
HHV:
120239269
(SH2B2)
BTA:
617840
(SH2B2)
BOM:
102271339
(SH2B2)
BIU:
109578305
(SH2B2)
BBUB:
102414008
(SH2B2)
BBIS:
104998968
(SH2B2)
CHX:
102185424
(SH2B2)
OAS:
101117815
(SH2B2)
BTAX:
128043347
(SH2B2)
ODA:
120878874
(SH2B2)
CCAD:
122432801
(SH2B2)
MREE:
136158582
(SH2B2)
MBEZ:
129545652
(SH2B2)
SSC:
100519708
(SH2B2)
CFR:
102520752
(SH2B2)
CBAI:
105067517
(SH2B2)
CDK:
105092381
(SH2B2)
VPC:
102526001
(SH2B2)
BACU:
103016923
(SH2B2)
BMUS:
118881351
(SH2B2)
LVE:
103088787
(SH2B2)
OOR:
101270777
(SH2B2)
DLE:
111182007
(SH2B2)
PCAD:
102992188
(SH2B2)
PSIU:
116740786
(SH2B2)
ECB:
100059630
EPZ:
103551716
(SH2B2)
EAI:
106839337
(SH2B2)
MYB:
102251356
(SH2B2)
MYD:
102754109
(SH2B2)
MMYO:
118656699
(SH2B2)
MLF:
102428884
(SH2B2)
MDT:
132233224
(SH2B2)
PKL:
118702713
(SH2B2)
EFUS:
103286248
(SH2B2)
MNA:
107526551
(SH2B2)
DRO:
112314753
(SH2B2)
SHON:
118992834
(SH2B2)
AJM:
119044712
(SH2B2)
PDIC:
114500317
(SH2B2)
PHAS:
123806264
(SH2B2)
MMF:
118642630
(SH2B2)
PPAM:
129083439
(SH2B2)
HAI:
109385028
(SH2B2)
RFQ:
117024428
(SH2B2)
PALE:
102898524
(SH2B2)
PGIG:
120591566
(SH2B2)
PVP:
105299711
(SH2B2)
RAY:
107511783
(SH2B2)
MJV:
108389845
(SH2B2)
TOD:
119241549
(SH2B2)
SARA:
101556672
(SH2B2)
SETR:
125997143
126011806
126029606
(SH2B2)
LAV:
100670637
(SH2B2)
TMU:
101348710
ETF:
101642562
(SH2B2)
DNM:
101433051
(SH2B2)
MDO:
100618553
(SH2B2)
GAS:
123246847
(SH2B2)
SHR:
100929846
(SH2B2)
AFZ:
127558636
PCW:
110221267
(SH2B2)
TVP:
118857090
(SH2B2)
OAA:
100090126
(SH2B2)
GGA:
771172
(SH2B2)
PCOC:
116228162
(SH2B2)
MGP:
100543269
(SH2B2)
CJO:
107322455
(SH2B2)
TPAI:
128083516
(SH2B2)
LMUT:
125703010
(SH2B2)
NMEL:
110407624
(SH2B2)
APLA:
101794843
(SH2B2)
ACYG:
106041497
(SH2B2)
CATA:
118254182
(SH2B2)
AFUL:
116497468
(SH2B2)
TGU:
101232958
(SH2B2)
LSR:
110482032
(SH2B2)
SCAN:
103820253
(SH2B2)
PMOA:
120507722
(SH2B2)
OTC:
121345777
(SH2B2)
PRUF:
121361670
(SH2B2)
GFR:
102044475
(SH2B2)
FAB:
101809934
(SH2B2)
OMA:
130261035
(SH2B2)
PHI:
102110271
(SH2B2)
PMAJ:
107213014
(SH2B2)
CCAE:
111937693
(SH2B2)
CCW:
104691112
(SH2B2)
CBRC:
103621612
(SH2B2)
ETL:
114056702
(SH2B2)
ZAB:
102073602
(SH2B2)
ZLE:
135455862
(SH2B2)
ACHL:
103803888
SVG:
106853438
(SH2B2)
MMEA:
130577767
(SH2B2)
HRT:
120761307
(SH2B2)
SATI:
136370019
(SH2B2)
FPG:
101923247
(SH2B2)
FCH:
102058092
(SH2B2)
CCRI:
104159591
SHAB:
115601826
(SH2B2)
ACUN:
113487045
(SH2B2)
TALA:
116964431
(SH2B2)
ACHC:
115347628
(SH2B2)
HALD:
104320041
HLE:
104835512
(SH2B2)
AGEN:
126039209
GCL:
127024549
CSTI:
104558350
LDI:
104345597
MNB:
103767889
DPUB:
104298371
(SH2B2)
BRHI:
104499980
EGZ:
104131790
(SH2B2)
NNI:
104016105
(SH2B2)
PCRI:
104038196
PADL:
103912918
(SH2B2)
AFOR:
103895702
(SH2B2)
FGA:
104080832
CLV:
102087394
(SH2B2)
MUI:
104536865
PGUU:
104468271
PLET:
104627223
EHS:
104515076
CMAC:
104481339
CUCA:
104058682
(SH2B2)
TEO:
104376111
BREG:
104638317
OHA:
104328756
(SH2B2)
ACAR:
104521297
CPEA:
104396232
(SH2B2)
CVF:
104286584
(SH2B2)
RTD:
128913113
(SH2B2)
AAM:
106497334
(SH2B2)
AROW:
112965037
(SH2B2)
NPD:
112956651
(SH2B2)
TGT:
104579620
(SH2B2)
DNE:
112987392
(SH2B2)
SCAM:
104146244
(SH2B2)
ASN:
102369800
(SH2B2)
AMJ:
102573426
(SH2B2)
CPOO:
109317009
(SH2B2)
GGN:
109293496
(SH2B2)
PSS:
102457660
(SH2B2)
CMY:
102947329
(SH2B2)
CCAY:
125624052
(SH2B2)
DCC:
119844467
(SH2B2)
CPIC:
101952717
(SH2B2)
TST:
117867544
(SH2B2)
CABI:
116823459
(SH2B2)
MRV:
120387464
(SH2B2)
ACS:
103281085
(sh2b2)
ASAO:
132763488
(SH2B2)
PVT:
110085138
(SH2B2)
SUND:
121917065
(SH2B2)
PBI:
103066811
(SH2B2)
PMUR:
107298583
(SH2B2)
CTIG:
120303978
(SH2B2)
TSR:
106556257
(SH2B2)
PGUT:
117667484
(SH2B2)
APRI:
131188805
(SH2B2)
PTEX:
113441614
(SH2B2)
NSS:
113415134
(SH2B2)
VKO:
123023533
(SH2B2)
PMUA:
114585341
(SH2B2)
PRAF:
128402587
(SH2B2)
ZVI:
118097208
(SH2B2)
HCG:
128336012
(SH2B2)
GJA:
107107679
(SH2B2)
STOW:
125445449
(SH2B2)
EMC:
129344980
(SH2B2)
XLA:
108708031
(sh2b2.L)
108709343
(sh2b2.S)
XTR:
100488327
(sh2b2)
NPR:
108801794
(SH2B2)
RTEM:
120927618
(SH2B2)
BBUF:
120994741
(SH2B2)
BGAR:
122922786
(SH2B2)
MUO:
115456485
(SH2B2)
GSH:
117349299
(SH2B2)
DRE:
100535524
(sh2b2)
SRX:
107720403
(sh2b2)
107750119
SANH:
107662582
107703035
SGH:
107551239
107573094
CCAR:
109062982
109062985
109081654
CAUA:
113058219
113115419
CGIB:
127973097
128028656
PTET:
122358353
LROH:
127177202
OMC:
131520995
PPRM:
120464477
RKG:
130097742
MAMB:
125249001
CIDE:
127495112
CERY:
137004891
MASI:
127421939
127430091
TROS:
130565015
TDW:
130428468
MANU:
129437638
IPU:
108280786
IFU:
128624090
PHYP:
113543006
(sh2b2)
SMEO:
124403198
TFD:
113640366
TVC:
132848756
TRN:
134302665
AMEX:
103023327
CMAO:
118797330
EEE:
113583021
(sh2b2)
CHAR:
105911005
TRU:
101065075
(sh2b2)
TFS:
130535587
TNG:
GSTEN00014764G001
LCO:
104924728
(sh2b2)
NCC:
104959775
(sh2b2)
TBEN:
117470369
CGOB:
115018020
PGEO:
117457390
GACU:
117554868
EMAC:
134880135
ELY:
117259860
EFO:
125888802
PLEP:
121943648
SLUC:
116047685
ECRA:
117941920
ESP:
116677519
(sh2b2)
PFLV:
114553207
(sh2b2)
GAT:
120824557
PPUG:
119210841
AFB:
129095817
CLUM:
117741478
PSWI:
130211104
CANA:
137791039
CVE:
137873415
MSAM:
119883611
SCHU:
122879674
CUD:
121527297
ALAT:
119006341
ASTR:
137596780
MZE:
101487223
(sh2b2)
ONL:
100707313
(sh2b2)
OAU:
116323615
OLA:
101159212
(sh2b2)
OML:
112149767
CSAI:
133441802
XMA:
102238410
(sh2b2)
XCO:
114133174
(sh2b2)
XHE:
116707740
(sh2b2)
PRET:
103474674
(sh2b2)
PFOR:
103136322
(sh2b2)
PLAI:
106957848
(sh2b2)
PMEI:
106917734
(sh2b2)
GAF:
122832109
PPRL:
129369914
CVG:
107081929
(sh2b2)
CTUL:
119797315
GMU:
124884355
NFU:
107380250
(sh2b2)
KMR:
108240837
ALIM:
106519398
(sh2b2)
NWH:
119411270
AOCE:
111575972
(sh2b2)
MCEP:
125013416
CSEM:
103378466
(sh2b2)
POV:
109647225
SSEN:
122773695
HHIP:
117772722
HSP:
118106320
PPLT:
128440077
SMAU:
118299338
LCF:
108900851
SDU:
111238129
(sh2b2)
SLAL:
111654118
XGL:
120792463
HCQ:
109526335
SSCV:
125972694
SBIA:
133504900
PEE:
133405371
PTAO:
133482222
BPEC:
110163693
(sh2b2)
MALB:
109974360
(sh2b2)
BSPL:
114868358
SJO:
128360325
SASA:
106567661
106581513
(sh2b2)
106603418
106613312
STRU:
115148799
115163923
115206668
(sh2b2)
OTW:
112257919
112265755
121839297
OMY:
110508074
110517470
110537537
OGO:
123992492
123999408
124006220
ONE:
115105487
(sh2b2)
OKI:
109881501
109883857
109892790
OKE:
118390685
118391110
118397000
127913929
SALP:
111982087
112070793
SNH:
120036159
120041788
120043855
CCLU:
121551286
121555684
121567672
ELS:
105005599
(sh2b2)
105011112
SFM:
108922468
108928101
PKI:
111841470
111847896
AANG:
118210337
118236428
LOC:
102687796
(sh2b2)
PSPA:
121308492
ARUT:
117429074
117430617
PSEX:
120531298
LCM:
102363625
(SH2B2)
CMK:
103188435
CPLA:
122564180
HOC:
132830315
LERI:
129710497
PMRN:
116936840
CIN:
100179111
SCLV:
120334299
AGA:
1271598
ACOZ:
120948407
AAG:
5564176
ASUA:
134224724
LLL:
129796805
PPAP:
129810124
AME:
552012
ACER:
108002942
ALAB:
122720156
ADR:
102677357
AFLR:
100866942
BIM:
100750156
BBIF:
117212242
BVK:
117236875
BVAN:
117155734
BHUN:
126868235
BTER:
100649645
BAFF:
126918451
BPYO:
122577858
BPAS:
132907869
FVI:
122526867
CCAL:
108623043
OBB:
114870892
OLG:
117600246
MGEN:
117229549
NMEA:
116430240
CGIG:
122397614
SOC:
105196716
MPHA:
105829507
AEC:
105145418
ACEP:
105618172
VEM:
105566700
HST:
105187796
DQU:
106747411
CFO:
105255999
FEX:
115240355
LHU:
105672917
PGC:
109864049
OBO:
105282573
PCF:
106791850
PFUC:
122515875
VPS:
122635211
VCRB:
124431463
VVE:
124955124
NVI:
100122053
CSOL:
105362487
LHT:
122499494
LBD:
127290177
MDL:
103578857
CGLO:
123260488
FAS:
105267227
DAM:
107039555
AGIF:
122848486
CINS:
118068334
VCAN:
122412999
CCIN:
107266688
TCA:
661724
AGRG:
126749413
126750121
ATD:
109602601
DVV:
126881883
NVL:
108568538
AGS:
114126632
BTAB:
109031472
CLEC:
106663614
NLU:
111057467
PHU:
Phum_PHUM231600
ZNE:
110839402
CSEC:
111874434
BROR:
134528885
134529264
MNZ:
135220871
MRJ:
136833189
(Lnk)
LSM:
121127841
TUT:
107362666
CSCU:
111618220
CVS:
136975284
(Lnk)
PTEP:
107445434
ABRU:
129969063
UDV:
129217234
BMY:
BM_BM9870
(Bm9870)
LOA:
LOAG_00959
HRF:
124147760
HRJ:
124286040
HASI:
137296070
MAEA:
128230306
128230387
LJP:
135476767
LLON:
135500151
RES:
135683306
» show all
Taxonomy
UniProt
Reference
PMID:
9856458
Authors
Qian X, Riccio A, Zhang Y, Ginty DD
Title
Identification and characterization of novel substrates of Trk receptors in developing neurons.
Journal
Neuron 21:1017-29 (1998)
DOI:
10.1016/s0896-6273(00)80620-0
Sequence
[rno:
114203
]
Reference
PMID:
9989826
Authors
Yokouchi M, Wakioka T, Sakamoto H, Yasukawa H, Ohtsuka S, Sasaki A, Ohtsubo M, Valius M, Inoue A, Komiya S, Yoshimura A
Title
APS, an adaptor protein containing PH and SH2 domains, is associated with the PDGF receptor and c-Cbl and inhibits PDGF-induced mitogenesis.
Journal
Oncogene 18:759-67 (1999)
DOI:
10.1038/sj.onc.1202326
LinkDB
All DBs
DBGET
integrated database retrieval system