KEGG ORTHOLOGY: K07366

ORTHOLOGY: K07366

Entry

K07366                      KO

Symbol

GRAP2, GADS

Name

GRB2-related adaptor protein 2

Pathway

map04660

T cell receptor signaling pathway

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    K07366  GRAP2, GADS; GRB2-related adaptor protein 2
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified
    K07366  GRAP2, GADS; GRB2-related adaptor protein 2
Domain-containing proteins not elsewhere classified [BR:ko04990]
Src homology (SH) domain-containing proteins
  Signal transducing adaptor proteins
   K07366  GRAP2, GADS; GRB2-related adaptor protein 2

Other DBs

GO:

0005070

Genes

HSA:	9402(GRAP2)

PTR:	744653(GRAP2)

PPS:	100989377(GRAP2)

GGO:	101143984(GRAP2)

PON:	100431748(GRAP2)

PPYG:

129023406(GRAP2)

NLE:	100589837(GRAP2)

HMH:	116458761(GRAP2)

SSYN:

129467402(GRAP2)

MCC:	704410(GRAP2)

MCF:	101925658(GRAP2)

MTHB:

126963621

MNI:	105464411(GRAP2)

CSAB:

103223352(GRAP2)

CATY:

105572793(GRAP2)

PANU:

101015618(GRAP2)

TGE:	112633561(GRAP2)

MLEU:

105538847(GRAP2)

RRO:	104675176(GRAP2)

RBB:	108520472(GRAP2)

TFN:	117096456(GRAP2)

PTEH:

111548988(GRAP2)

CANG:

105527758(GRAP2)

CJC:	100402356(GRAP2)

SBQ:	101040900(GRAP2)

CIMI:

108315290(GRAP2)

ANAN:

105721813(GRAP2)

CSYR:

103276693(GRAP2)

MMUR:

105858605(GRAP2)

LCAT:

123640332(GRAP2)

PCOQ:

105805179(GRAP2)

OGA:	100966308(GRAP2)

MMU:	17444(Grap2)

MCAL:

110310910(Grap2)

MPAH:

110334916(Grap2)

RNO:	366962(Grap2)

MCOC:

116076173(Grap2)

ANU:	117718904(Grap2)

ASYL:

127668149(Grap2)

MUN:	110550441(Grap2)

CGE:	100769885(Grap2)

MAUA:

101835561(Grap2)

PROB:

127225815(Grap2)

PLEU:

114694288(Grap2)

MORG:

121461330(Grap2)

MFOT:

126492127

AAMP:

119822889(Grap2)

NGI:	103748559(Grap2)

HGL:	101722049(Grap2)

CPOC:

100733134(Grap2)

CCAN:

109693040(Grap2)

DORD:

105992035(Grap2)

DSP:	122123584(Grap2)

PLOP:

125358143(Grap2)

NCAR:

124981907

MMMA:

107155772(Grap2)

ITI:	101960854(Grap2)

OCU:

103352473

OPI:	101521080(GRAP2)

TUP:	102477022(GRAP2)

GVR:	103591684(GRAP2)

CFA:	481241(GRAP2)

CLUD:

112667502(GRAP2)

VVP:	112934064(GRAP2)

VLG:	121490484(GRAP2)

NPO:	129511730(GRAP2)

AML:	100464140(GRAP2)

UMR:	103676366(GRAP2)

UAH:	113241753(GRAP2)

UAR:	123780895(GRAP2)

ELK:

111157579

LLV:

125107389

MPUF:

101682935(GRAP2)

MNP:	132019201(GRAP2)

MLK:	131839504(GRAP2)

NVS:	122891188(GRAP2)

ORO:	101367527(GRAP2)

EJU:	114218301(GRAP2)

ZCA:	113921947(GRAP2)

MLX:	117998652(GRAP2)

NSU:	110578176(GRAP2)

LWW:	102750888(GRAP2)

FCA:	101084554(GRAP2)

PYU:	121040311(GRAP2)

PCOO:

112863578(GRAP2)

PBG:	122472787(GRAP2)

PVIV:

125169714(GRAP2)

LRUF:

124501066

LGF:	123591509(GRAP2)

AJU:

106979951

PTG:	102951258(GRAP2)

PPAD:

109265593(GRAP2)

PUC:

125920359

PLEZ:

122225153(GRAP2)

HHV:	120235349(GRAP2)

BTA:	522346(GRAP2)

BOM:	102268265(GRAP2)

BIU:	109559835(GRAP2)

BBUB:

102392054(GRAP2)

BBIS:

104984121(GRAP2)

CHX:	102185639(GRAP2)

OAS:	101107589(GRAP2)

BTAX:

128048780(GRAP2)

CSUM:

138079216(GRAP2)

ODA:	120857615(GRAP2)

CCAD:

122423786(GRAP2)

MREE:

136160351(GRAP2)

OVR:	110126970(GRAP2)

MBEZ:

129537050(GRAP2)

SSC:	100516438(GRAP2)

CFR:	102519194(GRAP2)

CBAI:

105073098(GRAP2)

CDK:	105091925(GRAP2)

VPC:	102532612(GRAP2)

BACU:

103018628(GRAP2)

BMUS:

118902251(GRAP2)

LVE:	103082483(GRAP2)

OOR:	101284435(GRAP2)

LALB:

132528874(GRAP2)

DLE:

111186270

PCAD:

102985951(GRAP2)

PSIU:

116760926(GRAP2)

NASI:

112394674(GRAP2)

ECB:	100055418(GRAP2)

EPZ:	103550722(GRAP2)

EAI:	106842440(GRAP2)

MYB:	102263629(GRAP2)

MYD:	102763364(GRAP2)

MMYO:

118651416(GRAP2)

MLF:	102436485(GRAP2)

MDT:	132226929(GRAP2)

MYUM:

139007584(GRAP2)

PKL:	118730332(GRAP2)

EFUS:

103289066(GRAP2)

MNA:	107531243(GRAP2)

DRO:	112321921(GRAP2)

SHON:

119002503(GRAP2)

AJM:	119060364(GRAP2)

PDIC:

114513652(GRAP2)

PHAS:

123816075(GRAP2)

MMF:	118623883(GRAP2)

PPAM:

129077840(GRAP2)

HAI:	109392227(GRAP2)

RFQ:	117028022(GRAP2)

PALE:

102895856(GRAP2)

PGIG:

120602991(GRAP2)

PVP:	105298067(GRAP2)

RAY:	107500813(GRAP2)

MJV:	108397371(GRAP2)

TOD:	119247238(GRAP2)

SARA:

101539686(GRAP2)

SFUM:

130044781(GRAP2)

SETR:

126006373(GRAP2)

LAV:	100661947(GRAP2)

TMU:

101346381

ETF:	101643682(GRAP2)

DNM:	101446575(GRAP2)

MDO:	100011047(GRAP2)

GAS:	123250072(GRAP2)

SHR:	100916308(GRAP2)

AFZ:

127538340

PCW:	110205809(GRAP2)

TVP:	118851550(GRAP2)

PBRV:

138172976(GRAP2)

OAA:	100076146(GRAP2)

TACU:

119937072(GRAP2)

GGA:	770756(GRAP2)

PCOC:

116233370(GRAP2)

MGP:	100545246(GRAP2)

CJO:	107312771(GRAP2)

TPAI:

128073576(GRAP2)

LMUT:

125684813(GRAP2)

NMEL:

110392466(GRAP2)

APLA:

101803146(GRAP2)

ACYG:

106035870(GRAP2)

CATA:

118250564(GRAP2)

AFUL:

116501776(GRAP2)

TGU:	100224458(GRAP2)

LSR:	110483845(GRAP2)

SCAN:

103813277(GRAP2)

PMOA:

120510113(GRAP2)

OTC:	121342390(GRAP2)

PRUF:

121361144(GRAP2)

ATRC:

139588048(GRAP2)

GFR:	102037047(GRAP2)

FAB:	101814008(GRAP2)

OMA:	130248211(GRAP2)

PHI:	102101043(GRAP2)

PMAJ:

107205226(GRAP2)

CCAE:

111934810(GRAP2)

CCW:	104696334(GRAP2)

CBRC:

103618103(GRAP2)

ACOE:

138104039(GRAP2)

ETL:	114055450(GRAP2)

ZAB:	102068153(GRAP2)

ZLE:	135457428(GRAP2)

ACHL:

103800567(GRAP2)

SVG:	106856929(GRAP2)

MMEA:

130587802(GRAP2)

HRT:	120751921(GRAP2)

SATI:

136361861(GRAP2)

CCIC:

134043221(GRAP2)

FPG:	101924449(GRAP2)

FCH:	102056862(GRAP2)

CCRI:

104165262(GRAP2)

NNT:	104402733(GRAP2)

SHAB:

115605639(GRAP2)

ACUN:

113491293(GRAP2)

TALA:

104366869(GRAP2)

ACHC:

115352822(GRAP2)

HALD:

104322650(GRAP2)

HLE:	104828572(GRAP2)

AGEN:

126047720

HHAR:

128143463(GRAP2)

GCL:

127013854

CSTI:

104552483(GRAP2)

LDI:	104347771(GRAP2)

MNB:	103772339(GRAP2)

DPUB:

104302009(GRAP2)

PPUS:

135181809(GRAP2)

AVIT:

104273178

BRHI:

104501593(GRAP2)

EGZ:	104134242(GRAP2)

NNI:	104021699(GRAP2)

PCRI:

104031374(GRAP2)

PCAO:

104051848(GRAP2)

PADL:

103915696(GRAP2)

AFOR:

103907877(GRAP2)

FGA:	104074054(GRAP2)

GSTE:

104259467(GRAP2)

CLV:	102094066(GRAP2)

MUI:	104540416(GRAP2)

PGUU:

104461575(GRAP2)

PLET:

104618791(GRAP2)

EHS:	104515592(GRAP2)

CMAC:

104485203(GRAP2)

CUCA:

104055512(GRAP2)

TEO:	104377663(GRAP2)

BREG:

104641829(GRAP2)

OHA:	104329867(GRAP2)

ACAR:

104526308(GRAP2)

CPEA:

104397798(GRAP2)

CVF:	104288373(GRAP2)

RTD:	128904145(GRAP2)

CRID:

134510407(GRAP2)

AAM:	106488226(GRAP2)

AROW:

112965725(GRAP2)

NPD:	112946461(GRAP2)

TGT:	104574093(GRAP2)

DNE:	112983485(GRAP2)

SCAM:

104137885(GRAP2)

ASN:	102369060(GRAP2)

AMJ:	102566605(GRAP2)

CPOO:

109316704(GRAP2)

GGN:	109295973(GRAP2)

PSS:	102449081(GRAP2)

CMY:	102942429(GRAP2)

CCAY:

125629280(GRAP2)

DCC:	119850079(GRAP2)

CPIC:

101930945(GRAP2)

TST:	117880192(GRAP2)

CABI:

116829260(GRAP2)

MRV:	120381171(GRAP2)

ACS:	100565830(grap2)

ASAO:

132775964(GRAP2)

PVT:	110076015(GRAP2)

SUND:

121930348(GRAP2)

PBI:	103056582(GRAP2)

PMUR:

107293064 107299450

CTIG:

120304668(GRAP2)

PGUT:

117655573(GRAP2)

APRI:

131201953(GRAP2)

PTEX:

113433820(GRAP2)

NSS:	113432706(GRAP2)

VKO:	123036444(GRAP2)

PMUA:

114605938(GRAP2)

PRAF:

128422323(GRAP2)

ZVI:	118091351(GRAP2)

HCG:	128327816(GRAP2)

GJA:	107117113(GRAP2)

STOW:

125435092(GRAP2)

EMC:	129336305(GRAP2)

XLA:	108714531(grap2.L) 108715763(grap2.S)

XTR:	100492322(grap2)

NPR:	108794685(GRAP2)

RTEM:

120945424(GRAP2)

BBUF:

120979345(GRAP2)

BGAR:

122943915(GRAP2)

PWL:	138292586(GRAP2)

MUO:	115460233 115477442

GSH:	117353518(GRAP2)

DRE:	393651(grap2b) 550452(grap2a)

SRX:	107705908 107732893 107733828 107738003

SANH:

107666674(grap2) 107680873 107681416 107690235

SGH:	107551143 107555100 107558520 107561352

CCAR:

109054308(grap2a) 109092100 122137604

CAUA:

113042885 113047003 113089785 113095173

CGIB:

127948909 127953264 127959424 128015291

PTET:

122333315(grap2b) 122341482(grap2a)

LROH:

127163319(grap2a) 127166301(grap2b)

OMC:	131537140(grap2a) 131541800(grap2b)

PPRM:

120467952(grap2b) 120490248(grap2a)

RKG:	130077389(grap2a) 130078829(grap2b)

MAMB:

125274418(grap2b) 125276064(grap2a)

CIDE:

127509410 127513846

CERY:

137011286(grap2b) 137017537(grap2a)

MASI:

127446175 127450590 127451340

TROS:

130556951(grap2b) 130561643(grap2a)

TDW:	130424645(grap2b) 130426303(grap2a)

MANU:

129436162(grap2a) 129450659(grap2b)

PDAB:

135720797 135758994 135769302 135783246

IPU:	108273087(grap2b) 108276461(grap2a)

IFU:	128615916(grap2b) 128624775(grap2a)

PHYP:

113523792 113538511

SMEO:

124388283(grap2b) 124396796

TFD:	113634596(grap2b) 113641404

TVC:	132844909(grap2b) 132860900

CGAR:

128526751(grap2b) 128544855

NGRA:

132884833(grap2b)

TRN:	134317298(grap2b) 134335896(grap2a)

AMEX:

103029038(grap2a) 103042502(grap2b)

CMAO:

118807875(grap2b) 118821629(grap2a)

EEE:	113572885 113579332

CHAR:

105892193 105908850(grap2b)

SPIL:

134076590(grap2a) 134092198(grap2b)

TRU:	101063794 115250026

TFS:	130515548(grap2a)

TNG:	GSTEN00021225G001

LCO:	104925984 104934494

NCC:

104946499

TBEN:

117471627 117493249(grap2a)

CGOB:

115012821

PGEO:

117451520(grap2a) 117453345

GACU:

117548830(grap2a) 117560710

EMAC:

134862781(grap2b) 134878214(grap2a)

ELY:	117255796 117268174(grap2a)

EFO:	125879866(grap2a) 125885610(grap2b)

PLEP:

121942460(grap2b) 121956576(grap2a)

SLUC:

116042941(grap2b) 116063984(grap2a)

ECRA:

117952601 117957551(grap2a)

ESP:	116702708 116704738

PFLV:

114569791 114573209

GAT:	120827367(grap2a)

PPUG:

119218068(grap2b) 119220970(grap2a)

AFB:	129096243(grap2b) 129098742(grap2a)

CLUM:

117730886(grap2b) 117735538(grap2a)

PSWI:

130189267(grap2a)

CANA:

137786779(grap2a) 137804829

CVE:	137871564(grap2b) 137884128(grap2a)

MSAM:

119884788 119894394(grap2a) 119898605(grap2b)

SCHU:

122869190(grap2a) 122872875(grap2b)

CUD:	121508651(grap2b) 121529117(grap2a)

SPUL:

138594975(grap2b) 138608279(grap2a)

LMIX:

132987060 132995723(grap2a)

ALAT:

119013834(grap2a) 119023175

ASTR:

137610080(grap2a)

MZE:	101476158 101487152

ONL:	100710037 100710443

OAU:	116314240(grap2a) 116317353(grap2b)

OLA:

101165394

OML:	112145869(grap2a)

CSAI:

133422321(grap2a)

XMA:	102221954(grap2)

XCO:	114159685(grap2)

XHE:	116736185(grap2)

PRET:

103469445(grap2)

PFOR:

103153057

PLAI:

106940006

PMEI:

106934049

GAF:	122822009(grap2a)

PPRL:

129373783(grap2a)

CVG:

107082021

CTUL:

119781857 119781864(grap2a)

GMU:	124862430 124863830

NFU:

107373826

KMR:	108237714(grap2a)

ALIM:

106518880(grb2)

NWH:	119421313(grap2a)

AOCE:

111562788(grap2a) 111577597(grap2b)

EJA:	138207865(grap2a) 138209256(grap2b)

BFRE:

138615639(grap2b) 138631257(grap2a)

MCEP:

124997231(grap2a)

CSEM:

103392516

POV:	109634144(grap2)

SSEN:

122784794(grap2a)

SSOE:

131474917(grap2a)

HHIP:

117766649(grap2a)

HSP:	118123760(grap2a)

PPLT:

128458922(grap2a)

SMAU:

118289153(grap2a) 118312635(grap2b)

LCF:	108888612(grap2a) 108889070

SDU:	111217690(grap2) 111235891

SLAL:

111644868 111671836(grap2)

XGL:	120783323(grap2a)

HCQ:

109527816

SSCV:

125983575

SBIA:

133515003

PEE:	133414774(grap2a)

PTAO:

133465565(grap2a)

BPEC:

110167800

ENY:	140357647(grap2a)

MALB:

109962815(grap2)

BSPL:

114860738(grap2a) 114861606

SJO:	128365075 128378703(grap2a)

SSCO:

133986692 133999454(grap2a)

GMH:	115532103(grap2)

SASA:

100195406(grap2) 106590884 106592503 106606931

STRU:

115147431 115171457 115188640 115202873

OTW:	112234099 112258950(grap2a)

OMY:	110486621 110526262 110538587 118938202

OGO:	124000719 124002650 124015521

ONE:	115104318 115121782

OKI:	109879547 109881079 109893567

OKE:	118365643 118365644(grap2a) 127919227 127932378(grap2b)

OMM:	135530551 135532934 135532935 135554396 135555374

OCLA:

139364974 139394401 139394481 139421457 139423756

SNH:	120032778 120034550 120044643

CCLU:

121551046 121555863 121568936

ELS:	105022952 105031184

OEP:	134016299 134036479(grap2a)

SFM:	108925948(grap2) 108930676

PKI:	111843314 111859739

AANG:

118216785 118221935

AROT:

135243087 135248798

CCOG:

133114410 133121736

LOC:	102691949(grap2)

PSPA:

121306162(grap2a)

ARUT:

117433004 117968009

PSEX:

120536966(grap2a)

LCM:	102353245(GRAP2)

CMK:	103189407(grap2a)

RTP:

109924375

CPLA:

122542100(grap2a)

HOC:	132831260(grap2a)

LERI:

SPU:

LPIC:

GAE:

ATEN:

Reference

PMID:9878555

Authors

Qiu M, Hua S, Agrawal M, Li G, Cai J, Chan E, Zhou H, Luo Y, Liu M

Title

Molecular cloning and expression of human grap-2, a novel leukocyte-specific SH2- and SH3-containing adaptor-like protein that binds to gab-1.

Journal

Biochem Biophys Res Commun 253:443-7 (1998)
DOI:10.1006/bbrc.1998.9795

Sequence

[hsa:9402]

LinkDB

DBGET integrated database retrieval system