KEGG   ORTHOLOGY: K07835
Entry
K07835                      KO                                     
Symbol
RALB
Name
Ras-related protein Ral-B
Pathway
map04014  Ras signaling pathway
map04015  Rap1 signaling pathway
map04072  Phospholipase D signaling pathway
map05200  Pathways in cancer
map05210  Colorectal cancer
map05212  Pancreatic cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    K07835  RALB; Ras-related protein Ral-B
   04015 Rap1 signaling pathway
    K07835  RALB; Ras-related protein Ral-B
   04072 Phospholipase D signaling pathway
    K07835  RALB; Ras-related protein Ral-B
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K07835  RALB; Ras-related protein Ral-B
  09162 Cancer: specific types
   05210 Colorectal cancer
    K07835  RALB; Ras-related protein Ral-B
   05212 Pancreatic cancer
    K07835  RALB; Ras-related protein Ral-B
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K07835  RALB; Ras-related protein Ral-B
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins
    K07835  RALB; Ras-related protein Ral-B
Membrane trafficking [BR:ko04131]
 Exocytosis
  Tethering complex
   Exocyst complex assembly proteins
    K07835  RALB; Ras-related protein Ral-B
GTP-binding proteins [BR:ko04031]
 Small (monomeric) G-proteins
  Ras Family
   Ral
    K07835  RALB; Ras-related protein Ral-B
Genes
HSA: 5899(RALB)
PTR: 750044(RALB)
PPS: 100972167(RALB)
GGO: 101132362(RALB)
PON: 100174018(RALB)
PPYG: 129031693(RALB)
NLE: 100593053(RALB)
HMH: 116462901(RALB)
SSYN: 129472262(RALB)
MCC: 695852(RALB)
MCF: 101925782(RALB)
MTHB: 126933156
MNI: 105492471(RALB)
CSAB: 103216913(RALB)
CATY: 105588111(RALB)
PANU: 101018519(RALB)
TGE: 112617110 112617149
MLEU: 105542066(RALB)
RRO: 104672611(RALB)
RBB: 108542108(RALB)
TFN: 117095133(RALB)
PTEH: 111521675(RALB)
CANG: 105511507(RALB)
CJC: 100409022(RALB)
SBQ: 101052488(RALB)
CIMI: 108283736(RALB) 108301868
ANAN: 105728117(RALB)
CSYR: 103259987(RALB)
MMUR: 105863023(RALB)
LCAT: 123643581(RALB)
PCOQ: 105810655(RALB)
OGA: 100950310(RALB)
MMU: 64143(Ralb)
MCAL: 110291027(Ralb)
MPAH: 110321584(Ralb)
RNO: 116546(Ralb)
MCOC: 116097777(Ralb)
ANU: 117716566(Ralb)
ASYL: 127697815(Ralb)
MUN: 110546412(Ralb)
CGE: 100757867(Ralb)
MAUA: 101823011(Ralb)
PROB: 127236373(Ralb)
PLEU: 114680725 114700234(Ralb)
MORG: 121446581(Ralb)
MFOT: 126489885
AAMP: 119827528(Ralb)
NGI: 103732313(Ralb)
HGL: 101699253(Ralb)
CPOC: 100715093(Ralb)
CCAN: 109699956(Ralb)
DORD: 105988915(Ralb)
DSP: 122112437(Ralb)
PLOP: 125339312 125368361(Ralb)
NCAR: 124981356
MMMA: 107155719(Ralb)
ITI: 101976578(Ralb)
OCU: 100346449
OPI: 101524724(RALB)
TUP: 102486756(RALB)
GVR: 103602525(RALB)
CFA: 483881(RALB)
CLUD: 112647858(RALB)
VVP: 112934326(RALB)
VLG: 121482021(RALB)
NPO: 129503858(RALB)
AML: 100481993(RALB)
UMR: 103658585(RALB)
UAH: 113263462(RALB)
UAR: 123796600(RALB)
ELK: 111141953
LLV: 125096003
MPUF: 101692174(RALB)
MNP: 132013964(RALB)
MLK: 131826917(RALB)
NVS: 122902741(RALB)
ORO: 101379049(RALB)
EJU: 114207275(RALB)
ZCA: 113920644(RALB)
MLX: 118012552(RALB)
NSU: 110585663(RALB)
LWW: 102737196(RALB)
FCA: 101080471(RALB)
PYU: 121030421(RALB)
PCOO: 112848778(RALB)
PBG: 122481248(RALB)
PVIV: 125173493(RALB)
LRUF: 124514605
LGF: 123598792(RALB)
AJU: 106966391
PTG: 102968600(RALB)
PPAD: 109278771(RALB)
PUC: 125911927
PLEZ: 122228825(RALB)
HHV: 120233552(RALB)
BTA: 505238(RALB)
BOM: 102284066(RALB)
BIU: 109568603(RALB)
BBUB: 102396158(RALB)
BBIS: 105003573(RALB)
CHX: 100861145(RALB)
OAS: 101113566(RALB)
BTAX: 128064111(RALB)
CSUM: 138075473(RALB)
ODA: 120854715(RALB)
CCAD: 122453526(RALB)
MREE: 136165248(RALB)
OVR: 110137933(RALB)
MBEZ: 129535089 129537511(RALB)
SSC: 100624229(RALB)
CFR: 102523710(RALB)
CBAI: 105068776(RALB)
CDK: 105088329(RALB)
VPC: 102532874(RALB)
BACU: 103003598(RALB)
BMUS: 118898114(RALB)
LVE: 103077787(RALB)
OOR: 101279735(RALB)
LALB: 132522456(RALB)
DLE: 111170386(RALB)
PCAD: 102979041(RALB)
PSIU: 116756440(RALB)
NASI: 112409213(RALB)
ECB: 100060199(RALB)
EPZ: 103565218(RALB)
EAI: 106841827(RALB)
MYB: 102259631(RALB)
MYD: 102765818(RALB)
MMYO: 118661595(RALB)
MLF: 102417752(RALB)
MDT: 132238716(RALB)
MYUM: 139015377(RALB)
PKL: 118709567(RALB) 118718517
EFUS: 103287731(RALB)
MNA: 107534635(RALB)
DRO: 112313137(RALB)
SHON: 118989536(RALB)
AJM: 119050079(RALB)
PDIC: 114514369(RALB)
PHAS: 123810291(RALB)
MMF: 118625459(RALB)
PPAM: 129071736(RALB)
HAI: 109396687(RALB)
RFQ: 117026093(RALB)
PALE: 102899030(RALB)
PGIG: 120610347(RALB)
PVP: 105296141(RALB)
RAY: 107501432(RALB)
MJV: 108400050(RALB)
TOD: 119255748(RALB)
SARA: 101550413(RALB)
SFUM: 130018283(RALB)
SETR: 126008878(RALB)
LAV: 100669974(RALB)
TMU: 101342129
ETF: 101652430(RALB) 105978518
DNM: 101420195
MDO: 100010449(RALB)
GAS: 123242297(RALB)
SHR: 100922803(RALB)
AFZ: 127554319
PCW: 110192081(RALB)
TVP: 118839087(RALB)
PBRV: 138145259(RALB)
OAA: 100087330(RALB)
TACU: 119928633(RALB)
GGA: 424237(RALB)
PCOC: 116227357(RALB)
MGP: 100545371(RALB)
CJO: 107316773(RALB)
NMEL: 110399572(RALB)
APLA: 101804929(RALB)
ACYG: 106029877(RALB)
CATA: 118243141(RALB)
AFUL: 116490683(RALB)
TGU: 100218799(RALB)
LSR: 110468310(RALB)
SCAN: 103814326(RALB)
PMOA: 120505126(RALB)
OTC: 121336637(RALB)
PRUF: 121356513(RALB)
ATRC: 139593837(RALB)
GFR: 102032363(RALB)
FAB: 101820873(RALB)
OMA: 130255609(RALB)
PHI: 102110383(RALB)
PMAJ: 107207363(RALB)
CCAE: 111932223(RALB)
CCW: 104694002(RALB)
CBRC: 103619692(RALB)
ACOE: 138113123(RALB)
ETL: 114055512(RALB)
ZAB: 102075344(RALB)
ZLE: 135450265(RALB)
ACHL: 103799222(RALB)
SVG: 106850433(RALB)
MMEA: 130572811(RALB)
HRT: 120754987(RALB)
SATI: 136363644(RALB)
CCIC: 134047169(RALB)
FPG: 101920142(RALB)
FCH: 102047833(RALB)
CCRI: 104157996(RALB)
NNT: 104401716(RALB)
SHAB: 115608524(RALB)
ACUN: 113482304(RALB)
TALA: 104356508(RALB)
ACHC: 115343165(RALB)
HALD: 104315619(RALB)
HLE: 104832450(RALB)
AGEN: 126040329
HHAR: 128143979(RALB)
GCL: 127018291
CSTI: 104551990(RALB)
LDI: 104341664(RALB)
MNB: 103777193(RALB)
DPUB: 104309765(RALB)
PPUS: 135182909(RALB)
AVIT: 104278679(RALB)
BRHI: 104499011(RALB)
EGZ: 104131512(RALB)
NNI: 104018921(RALB)
PCRI: 104026226(RALB)
PCAO: 104043822(RALB)
PADL: 103919612(RALB)
AFOR: 103895397(RALB)
FGA: 104083069(RALB)
GSTE: 104257842(RALB)
CLV: 102087902(RALB)
MUI: 104535264(RALB)
PGUU: 104470159(RALB)
PLET: 104620440(RALB)
EHS: 104506460(RALB)
CMAC: 104484908(RALB)
CUCA: 104067696(RALB)
TEO: 104382426(RALB)
BREG: 104632689(RALB)
OHA: 104337267(RALB)
ACAR: 104522718(RALB)
CPEA: 104387312(RALB)
CVF: 104288468(RALB)
RTD: 128913192(RALB)
CRID: 134518357(RALB)
AAM: 106499275(RALB)
AROW: 112973840(RALB)
NPD: 112959873(RALB)
TGT: 104576655(RALB) 104579595
DNE: 112994218(RALB)
SCAM: 104139608(RALB)
ASN: 102382646(RALB)
AMJ: 102572336(RALB)
CPOO: 109322858(RALB)
GGN: 109301435(RALB)
PSS: 102448056(RALB)
CMY: 102943557(RALB)
CCAY: 125644934(RALB)
DCC: 119863226(RALB)
CPIC: 101940489(RALB)
TST: 117884673(RALB)
CABI: 116834028(RALB)
MRV: 120374389(RALB)
ACS: 100563317(ralb)
ASAO: 132774294(RALB)
PVT: 110085444(RALB)
SUND: 121931550(RALB)
PBI: 103053365
PMUR: 107298364(RALB)
CTIG: 120297105(RALB)
TSR: 106543502(RALB)
PGUT: 117668435(RALB)
APRI: 131204349(RALB)
PTEX: 113441223(RALB)
NSS: 113410769(RALB)
VKO: 123027339(RALB)
PMUA: 114603722(RALB)
PRAF: 128420992(RALB)
ZVI: 118091628(RALB)
HCG: 128336567(RALB)
GJA: 107106797(RALB)
STOW: 125426246(RALB)
EMC: 129323760(RALB)
XLA: 399338(ralb.L) 432329(ralb.S)
XTR: 100124895(ralb)
NPR: 108800749
RTEM: 120944259(RALB)
BBUF: 121007431(RALB)
BGAR: 122922549(RALB)
PWL: 138285094(RALB)
MUO: 115474564(RALB)
GSH: 117361027(RALB)
DRE: 415213(ralbb) 445255(ralba)
SRX: 107713003 107714348 107741991 107746258
SANH: 107657963 107660649 107661132 107694485
SGH: 107552396 107558355 107558370 107596059 107597482
CCAR: 109045607 109070924 109072691 109096064 109096835(ralba)
CAUA: 113053069 113055397 113108175 113108411 113110723
CGIB: 127965004 127968354 128019998 128021990
PTET: 122352050(ralba) 122353874
LROH: 127170971(ralba) 127173504(ralbb)
OMC: 131546844(ralba) 131549480(ralbb)
PPRM: 120480486(ralbb) 120489846(ralba)
RKG: 130078725(ralba)
MAMB: 125256548(ralbb) 125270189(ralba)
CIDE: 127518727 127522773
CERY: 137021354(ralbb) 137035599(ralba)
MASI: 127426043 127427731 127447088 127448523
TROS: 130555519 130555520 130571107(ralbb)
TDW: 130410617(ralbb) 130427389(ralba)
MANU: 129427877(ralbb) 129451571(ralba)
PDAB: 135733424(ralba) 135740757(ralbb)
IPU: 108266680(ralba) 108271259(ralbb)
IFU: 128608741(ralba) 128613985(ralbb)
PHYP: 113525958(ralb) 113536513
SMEO: 124382708(ralba) 124391173(ralbb)
TFD: 113653887 113654266(ralba)
TVC: 132850121(ralba) 132856143
CGAR: 128524153(ralba) 128542765
NGRA: 132891794(ralba) 132899238
TRN: 134323979(ralba) 134331706(ralbb)
AMEX: 103025071(ralba) 103027321(ralbb)
CMAO: 118818956(ralbb) 118822035(ralba)
EEE: 113592220(ralb)
CHAR: 105901921(ralba) 105905684
SPIL: 134071432 134078712(ralba)
TRU: 101065425 101079195
TFS: 130523469 130529492
TNG: GSTEN00019410G001 GSTEN00026638G001
LCO: 104927621(ralb) 104931303
NCC: 104955285(ralb) 104965661
TBEN: 117485580(ralba) 117486812
CGOB: 115017465 115026219(ralb)
PGEO: 117466609(ralba)
GACU: 117544086(ralba) 117552813
EMAC: 134861115 134867113(ralba)
ELY: 117250115 117251556(ralba)
EFO: 125884855 125899693(ralba)
PLEP: 121948985(ralba) 121963772
SLUC: 116037724(ralba) 116044853
ECRA: 117939675 117953265(ralba)
ESP: 116698059
PFLV: 114551027 114564100
GAT: 120833627(ralba)
PPUG: 119221001 119228493(ralba)
AFB: 129104209(ralba) 129111618
CLUM: 117742018 117750356(ralba)
PSWI: 130204394 130207700(ralba)
CANA: 137782760 137803531
CVE: 137865902(ralba)
MSAM: 119903893(ralba) 119912932
SCHU: 122872037 122885725(ralba)
CUD: 121506473 121522657(ralba)
SPUL: 138592148(ralba) 138603335
LMIX: 132959361 132986991(ralba)
ALAT: 119015275 119025787(ralba)
ASTR: 137591297 137605045(ralba)
MZE: 101476492 101477326
ONL: 100704913 100708421(ralb)
OAU: 116315002(ralba) 116320492
OLA: 101156149 101157118
OML: 112154909(ralba) 112156829
CSAI: 133425272 133446151(ralba)
XMA: 102232228 102234308
XCO: 114140641 114147926(ralb)
XHE: 116715714 116723181
PRET: 103456799 103460652(ralb)
PFOR: 103145316(ralb) 103150928
PLAI: 106947518(ralb) 106950370
PMEI: 106924464 106931543(ralb)
GAF: 122826972
PPRL: 129356803 129361201(ralba)
CVG: 107095444 107096025
CTUL: 119776843(ralba) 119795378
GMU: 124861496 124870832(ralba)
NFU: 107373554(ralb) 107384566
KMR: 108228880 108238567(ralba)
ALIM: 106512769 106517621 106523151(ralb)
NWH: 119419044(ralba) 119428752
AOCE: 111571829(ralba) 111584932
EJA: 138201332 138207109
BFRE: 138620981 138633844
MCEP: 125000680 125017626
CSEM: 103389824 103392290
POV: 109631385 109644906
SSEN: 122759843 122761198(ralba)
SSOE: 131451215 131455053(ralba)
HHIP: 117755353(ralba) 117777603
HSP: 118103551 118119977(ralba)
PPLT: 128430951 128455638(ralba)
SMAU: 118295368 118320507(ralba)
LCF: 108873209 108886876(ralba)
SDU: 111218222(ralb) 111235537
SLAL: 111646885 111668772(ralb)
XGL: 120797910 120801728(ralba)
HCQ: 109512301 109528711
SSCV: 125973757 125989494
SBIA: 133507349 133512109(ralba)
PEE: 133404158 133410482(ralba)
PTAO: 133480974 133486938(ralba)
BPEC: 110156219 110170683
ENY: 140359924 140364245
MALB: 109955770 109957153(ralb)
BSPL: 114846076 114847502
SJO: 128354697 128367842(ralba)
SSCO: 133976313 133992845(ralba)
GMH: 115532736(ralb) 115542383
SASA: 100195652(ralbb) 106575191 106582302 106586433
STRU: 115155626 115160965 115179692 115196011
OTW: 112225577 112238758(ralba) 112253806 112266531
OMY: 100305184(ralb) 110495888 110501794 110527501
OGO: 124008611 124010885 124044004 124047548
ONE: 115111153 115129689 115129772 115133631
OKI: 109868203 109871008 109890625 109906700
OKE: 118363741 118366896 118370206 118386332
OMM: 135519291 135542539 135543550 135547574
OCLA: 139373228 139380828 139401148 139413049
SALP: 111953435 111959601 111970935 111977347
SNH: 120033596 120051269 120058318 120064214
CCLU: 121537006(ralba) 121554855 121586957
ELS: 105019969 105024679(ralb)
OEP: 134007217 134017412(ralba)
SFM: 108930170 108930823
PKI: 111849483 111851761(ralb)
AANG: 118223034(ralba)
AROT: 135250452(ralba)
CCOG: 133124097(ralba)
LOC: 102687847(ralb)
PSPA: 121308188 121322489(ralba) 121322715
ARUT: 117412361 117426967 117972126
PSEX: 120530738
LCM: 102360618(RALB)
CMK: 103180434(ralba)
RTP: 109927477(ralba)
CPLA: 122551766(ralba)
HOC: 132817027(ralba)
LERI: 129699097(ralba) 129702906
SCLV: 120345367 120345368
AJJ: 139984223
 » show all
Reference
PMID:12888294
  Authors
Feig LA
  Title
Ral-GTPases: approaching their 15 minutes of fame.
  Journal
Trends Cell Biol 13:419-25 (2003)
DOI:10.1016/S0962-8924(03)00152-1
Reference
PMID:18756269
  Authors
Cascone I, Selimoglu R, Ozdemir C, Del Nery E, Yeaman C, White M, Camonis J
  Title
Distinct roles of RalA and RalB in the progression of cytokinesis are supported by distinct RalGEFs.
  Journal
EMBO J 27:2375-87 (2008)
DOI:10.1038/emboj.2008.166
  Sequence
[hsa:5899]
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