KEGG ORTHOLOGY: K08053

ORTHOLOGY: K08053

Entry

K08053                      KO

Symbol

RASA2, GAP1M

Name

Ras GTPase-activating protein 2

Pathway

map04010

MAPK signaling pathway

map04014

Ras signaling pathway

map05203

Viral carcinogenesis

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K08053  RASA2, GAP1M; Ras GTPase-activating protein 2
   04014 Ras signaling pathway
    K08053  RASA2, GAP1M; Ras GTPase-activating protein 2
09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    K08053  RASA2, GAP1M; Ras GTPase-activating protein 2

Other DBs

GO:

0005096

Genes

HSA:	5922(RASA2)

PTR:	460741(RASA2)

PPS:	100981149(RASA2)

GGO:	101136814(RASA2)

PON:	100444564(RASA2)

PPYG:

129032623(RASA2)

NLE:	100595161(RASA2)

HMH:	116461649(RASA2)

SSYN:

129491214(RASA2)

MCC:	715074(RASA2)

MCF:	101926820(RASA2)

MTHB:

126947414

MNI:	105469985(RASA2)

CSAB:

103241568(RASA2)

CATY:

105586356(RASA2)

PANU:

101025574(RASA2)

TGE:	112619290(RASA2)

MLEU:

105555637(RASA2)

RRO:	104674071(RASA2)

RBB:	108522272(RASA2)

TFN:	117084098(RASA2)

PTEH:

111526428(RASA2)

CANG:

105523397(RASA2)

CJC:	100413985(RASA2)

SBQ:	101029341(RASA2)

CIMI:

108300812(RASA2)

ANAN:

105706566(RASA2)

CSYR:

103250837

MMUR:

105870086(RASA2)

LCAT:

123630043(RASA2)

ERUF:

138386630(RASA2)

PCOQ:

105812871(RASA2)

OGA:	100946726(RASA2)

MMU:	114713(Rasa2)

MCAL:

110301714(Rasa2)

MPAH:

110327267(Rasa2)

RNO:	25597(Rasa2)

MCOC:

116073884(Rasa2)

ANU:	117693413(Rasa2)

ASYL:

127688696(Rasa2)

MMIU:

308434344(RASA2)

MUN:	110555293(Rasa2)

CGE:	100765379(Rasa2)

MAUA:

101831785(Rasa2)

PROB:

127238259(Rasa2)

PLEU:

114690976(Rasa2)

PMAV:

102920794(Rasa2)

MORG:

121464385(Rasa2)

MFOT:

126510661

AAMP:

119810331(Rasa2)

CNL:	130872930(Rasa2)

NGI:	103748289(Rasa2)

HGL:	101725433(Rasa2)

CPOC:

100730767(Rasa2)

CCAN:

109690889(Rasa2)

DORD:

105995972(Rasa2)

DSP:	122095267(Rasa2)

DMER:

138816033(Rasa2)

PLOP:

125342631(Rasa2)

NCAR:

124992970

SVUL:

306637595(RASA2)

MMMA:

107143146(Rasa2)

ITI:	101961915(Rasa2)

SCIL:

308652619(RASA2)

MAVE:

308263396(RASA2)

OCU:

100357503

OPI:	101534479(RASA2)

OCZ:	121172178(RASA2)

TUP:	102493211(RASA2)

GVR:	103602272(RASA2)

CFA:	485692(RASA2)

CLUD:

112660974(RASA2)

VVP:	112934956(RASA2)

VLG:	121478867(RASA2)

NPO:	129507037(RASA2)

AML:	105240212(RASA2)

UMR:	103681607(RASA2)

UAH:	113254007(RASA2)

UAR:	123788433(RASA2)

ELK:

111147253

LLV:

125098087

MPUF:

101693661(RASA2)

MNP:	132012181(RASA2)

MLK:	131825063(RASA2)

NVS:	122908552(RASA2)

MMAQ:

308350266(RASA2)

ORO:	101366946(RASA2)

EJU:	114205712(RASA2)

ZCA:	113916584(RASA2)

MLX:	118004584(RASA2)

MANO:

123863766(RASA2)

NSU:	110570821(RASA2)

LWW:	102738488(RASA2)

FCA:	101098329(RASA2)

PYU:	121033754(RASA2)

PCOO:

112849437(RASA2)

PBG:	122491919(RASA2)

PVIV:

125174824(RASA2)

LRUF:

124526300

LGF:	123611481(RASA2)

AJU:

106984995

PTG:	102972756(RASA2)

PPAD:

109260188(RASA2)

PUC:

125921970

PLEZ:

122230122(RASA2)

HHV:	120242649(RASA2)

CCRU:

144225496(RASA2)

BTA:	533491(RASA2)

BOM:	102271863(RASA2)

BIU:	109559667(RASA2)

BJV:	133249446(RASA2)

BBUB:

102398367(RASA2)

BKE:	129644105(RASA2)

BBIS:

105001782(RASA2)

CHX:	102181436(RASA2)

OAS:	101108362(RASA2)

OCAN:

138425589(RASA2)

BTAX:

128048762(RASA2)

CSUM:

138081156(RASA2)

ODA:	120858056(RASA2)

CCAD:

122445254(RASA2)

MREE:

136173408(RASA2)

OVR:	110128487(RASA2)

MBEZ:

129547049(RASA2)

SSC:	100515414(RASA2)

CFR:	102513532(RASA2)

CBAI:

105066827(RASA2)

CDK:	105086320(RASA2)

VPC:	102545882(RASA2)

BACU:

103013106(RASA2)

BMUS:

118894329(RASA2)

LVE:	103085645(RASA2)

OOR:	101278348(RASA2)

LALB:

132520894(RASA2)

GMF:	115862026(RASA2)

DDP:	132425032(RASA2)

SCOO:

307186724(RASA2)

PCRS:

137224760(RASA2)

DLE:	111179252(RASA2)

PCAD:

102987293(RASA2)

PSIU:

116752784(RASA2)

PPHC:

136122210(RASA2)

NASI:

112415835(RASA2)

HAMP:

307053196(RASA2)

ECB:	100063323(RASA2)

EPZ:	103556992(RASA2)

EAI:	106838119(RASA2)

MYB:	102242363(RASA2)

MYD:	102762518(RASA2)

MMYO:

118668111(RASA2)

MLF:	102420713(RASA2)

MDT:	132215483(RASA2)

MYUM:

139022401(RASA2)

PKL:	118715273(RASA2)

EFUS:

103296018(RASA2)

POTS:

308252165(RASA2)

MNA:	107534703(RASA2)

DRO:	112301113(RASA2)

SHON:

118990759(RASA2)

AJM:	119044847(RASA2)

PDIC:

114501324(RASA2)

PHAS:

123814395(RASA2)

MMF:	118632928(RASA2)

PPAM:

129088320(RASA2)

HAI:	109384570(RASA2)

RFQ:	117036947(RASA2)

RHII:

308507518(RASA2)

PALE:

102897741(RASA2)

PGIG:

120582154(RASA2)

PVP:	105290358(RASA2)

RAY:	107509413(RASA2)

MJV:	108410200(RASA2)

TOD:	119257714(RASA2)

SARA:

101540087(RASA2)

SFUM:

130030030(RASA2)

SETR:

126025533(RASA2)

LAV:	100655944(RASA2)

TMU:

101344154

ETF:	101649748(RASA2)

DNM:	101439000(RASA2)

MDO:	100020540(RASA2)

GAS:	123242771(RASA2)

SHR:	100935390(RASA2)

AFZ:

127553001

PCW:	110197216(RASA2)

TVP:	118848602(RASA2)

PBRV:

138174371(RASA2)

MLAO:

141490848(RASA2)

OAA:	100079072(RASA2)

TACU:

119930501(RASA2)

GGA:	424782(RASA2)

PCOC:

116230894(RASA2)

MGP:	100541873(RASA2)

CJO:	107318065(RASA2)

TPAI:

128082295(RASA2)

LMUT:

125697589(RASA2)

NMEL:

110397949(RASA2)

APLA:

101800023(RASA2)

AACU:

137861376(RASA2)

OJA:	118171625(RASA2)

BCLA:

308447344(RASA2)

ACYG:

106036176(RASA2)

ABRC:

308200120(RASA2)

CATA:

118247270(RASA2)

AFUL:

116492435(RASA2)

TGU:	100231090(RASA2)

LSR:	110473947(RASA2)

VMC:	128812272(RASA2)

VCHA:

128793059(RASA2)

AIB:	137480007(RASA2)

SCAN:

103815423(RASA2)

PMOA:

120508573(RASA2)

OTC:	121341149(RASA2)

PRUF:

121357961(RASA2)

ATRC:

139594922(RASA2)

MATE:

118690156(RASA2)

MAEN:

136560736(RASA2)

GFR:	102031397(RASA2)

FAB:	101811590(RASA2)

OMA:	130256837(RASA2)

PHI:	102108158(RASA2)

PMAJ:

107208734(RASA2)

CCAE:

111933520(RASA2)

CCW:	104693450(RASA2)

CBRC:

103624831(RASA2)

ACOE:

138114508(RASA2)

ETL:	114068733(RASA2)

ZAB:	102074232(RASA2)

ZLE:	135451537(RASA2)

ACHL:

103797572(RASA2)

SVG:	106854170(RASA2)

MMEA:

130574004(RASA2)

HRT:	120757370(RASA2)

SATI:

136365664(RASA2)

CFAI:

136295029(RASA2)

CCIC:

134047783(RASA2)

NNT:	104404365(RASA2)

SHAB:

115612042(RASA2)

POCC:

134174216(RASA2)

FPG:	101923999(RASA2)

FCH:	102050648(RASA2)

FRS:	119156680(RASA2)

CCRI:

104155312(RASA2)

ACUN:

113483517(RASA2)

ANOC:

141963109(RASA2)

SURA:

141947029(RASA2)

TALA:

104361913(RASA2)

ACHC:

115346976(RASA2)

HALD:

104321094(RASA2)

HLE:	104832245(RASA2)

AGEN:

126039687

HHAR:

128149292(RASA2)

BBUT:

142032751(RASA2)

GCL:

127020194

CSTI:

104561749(RASA2)

LDI:	104340036(RASA2)

MNB:	103781178(RASA2)

DPUB:

104300640(RASA2)

PPUS:

135186946(RASA2)

IIN:	128970490(RASA2)

AVIT:

104267625(RASA2)

BRHI:

104495456(RASA2)

EGZ:	104127074(RASA2)

NNI:	104016391(RASA2)

PCRI:

104024592(RASA2)

PCAO:

104049164(RASA2)

PARX:

142059769(RASA2)

PADL:

103917913(RASA2)

AFOR:

103905143(RASA2)

FGA:	104075059(RASA2)

CBOR:

142085847(RASA2)

GSTE:

104257534(RASA2)

CBOY:

140654483(RASA2)

MAME:

142412304(RASA2)

CLV:	102085277(RASA2)

CNIC:

135991446(RASA2)

NMAY:

308043768(RASA2)

MUI:	104545556(RASA2)

PGUU:

104468353(RASA2)

PLET:

104620786(RASA2)

EHS:	104503256(RASA2)

CMAC:

104485395(RASA2)

CUCA:

104063706(RASA2)

PCUR:

138724452(RASA2)

TEO:	104376246(RASA2)

BREG:

104633296(RASA2)

GAME:

129209849(RASA2)

OHA:	104327051(RASA2)

ACAR:

104523762(RASA2)

CEUR:

306721831(RASA2)

CPEA:

104392257(RASA2)

HEK:	139799779(RASA2)

CVF:	104291139(RASA2)

RTD:	128911110(RASA2)

CRID:

134517307(RASA2)

LMIC:

141745275(RASA2)

NARQ:

141468225(RASA2)

AAM:	106485853(RASA2)

AROW:

112976115(RASA2)

NPD:	112947886(RASA2)

TGT:	104580226(RASA2)

DNE:	112984090(RASA2)

SCAM:

104153228(RASA2)

ASN:	102381154(RASA2)

AMJ:	102559499(RASA2)

CPOO:

109308598(RASA2)

GGN:	109288159(RASA2)

PSS:	102457523(RASA2)

CIZ:	142018491(RASA2)

CMY:	102935730(RASA2)

CCAY:

125643173(RASA2)

LKP:	140917309(RASA2)

NDS:	141993969(RASA2)

DCC:	119861029(RASA2)

CPIC:

101941611(RASA2)

TST:	117882775(RASA2)

EOB:	135883492(RASA2)

CABI:

116816425(RASA2)

EMQ:	137159587(RASA2)

ACS:	100562741(rasa2)

ASAO:

132770643(RASA2)

PVT:	110078462(RASA2)

SUND:

121925400(RASA2)

PBI:	103048785 103059792

PMUR:

107287755(RASA2)

CTIG:

120314402(RASA2)

TSR:	106541866(RASA2)

PGUT:

117678339(RASA2)

PCAE:

139318106(RASA2)

APRI:

131200623(RASA2)

PTEX:

113436863(RASA2)

NSS:	113410083(RASA2)

VKO:	123024676(RASA2)

PMUA:

114597829(RASA2)

PRAF:

128414606(RASA2)

ZVI:	118093483(RASA2)

HCG:	128352519(RASA2)

GJA:	107112354(RASA2)

STOW:

125437507(RASA2)

EMC:	129332131(RASA2)

XLA:	108717133(rasa2.L)

XTR:	100036638(rasa2)

NPR:	108790146(RASA2)

RTEM:

120936457(RASA2)

ACAT:

141139486(RASA2)

PADS:

140328244(RASA2)

BBUF:

120997626(RASA2)

BGAR:

122934403(RASA2)

DTC:	141091184(RASA2)

HSQ:	130361456(RASA2)

PCOB:

134909139(RASA2)

PWL:	138265846(RASA2)

MUO:	115478936(RASA2)

GSH:	117366719(RASA2)

DRE:	100331895(rasa2)

DAES:

130245319(rasa2)

SRX:	107710946 107714449

SANH:

107679023 107684605

SGH:	107557841(rasa2) 107566682

CCAR:

109087818(rasa2) 109087896

CAUA:

113061711 113118603

CGIB:

127934469 127977607

PTET:

122362853(rasa2)

LROH:

127180325(rasa2)

GRF:	141345748(rasa2) 141346171

OMC:	131524327(rasa2)

PPRM:

120473869(rasa2)

RKG:	130073783(rasa2)

SCEP:

307160339(rasa2)

PPHX:

307003391(rasa2)

MAMB:

125254716(rasa2)

CIDE:

127499379

CERY:

137023104(rasa2)

MASI:

127416747 127456453

TROS:

130562658(rasa2)

TDW:	130435664(rasa2)

MANU:

129418598(rasa2)

PDAB:

135746419(rasa2)

IPU:	108264552(rasa2)

IFU:	128606860(rasa2)

PHYP:

113526614(rasa2)

SMEO:

124396175(rasa2)

TFD:	113633930(rasa2)

TVC:	132851056(rasa2)

CGAR:

128528373(rasa2)

NGRA:

132887837(rasa2)

TRN:	134322989(rasa2)

AMEX:

103036376(rasa2)

CMAO:

118818021(rasa2)

EEE:	113587612(rasa2)

CHAR:

105902821(rasa2)

SPIL:

134099113(rasa2)

ASAD:

121683844(rasa2)

TBEN:

117469987(rasa2)

CGOB:

115017545(rasa2)

PGEO:

117457880(rasa2)

GACU:

117545999(rasa2)

EMAC:

134880277(rasa2)

ELY:	117259720(rasa2)

EFO:	125888540(rasa2)

PLEP:

121943475(rasa2)

SLUC:

116045572(rasa2)

SVIT:

144515517(rasa2)

ECRA:

117942365(rasa2)

ESP:	116686956(rasa2)

PFLV:

114552347(rasa2)

PFLT:

120548081(rasa2)

GAT:	120819274(rasa2)

PPUG:

119211403(rasa2)

AFB:	129106304(rasa2)

PSWI:

130211351

CANA:

137790313(rasa2)

TBU:	306742310(rasa2)

CVE:	137871371(rasa2)

AMIR:

142959576(rasa2)

MSAM:

119882876(rasa2)

SCHU:

122879698(rasa2)

EARM:

139285118(rasa2)

CUD:	121521287(rasa2)

SPUL:

138596917(rasa2)

LMIX:

132980273(rasa2)

HTC:	141797664(rasa2)

ALAT:

119009361(rasa2)

ASTR:

137596261(rasa2)

PKLU:

139199745(rasa2)

LCO:	104924170(rasa2)

AMMM:

307271422(rasa2)

MZE:	101475471(rasa2)

ONL:	100701535(rasa2)

OAU:	116330391(rasa2)

OLA:	101167470(rasa2)

OML:	112149195(rasa2)

CSAI:

133441655(rasa2)

XMA:	102218452(rasa2)

XCO:	114161894(rasa2)

XHE:	116707686(rasa2)

PRET:

103474445(rasa2)

PFOR:

103152930(rasa2)

PLAI:

106945709(rasa2)

PMEI:

106931566(rasa2)

GAF:	122832154(rasa2)

PPRL:

129359016(rasa2)

CVG:	107083496(rasa2)

CTUL:

119771818(rasa2)

GMU:	124883928(rasa2)

NFU:	107380489(rasa2)

KMR:	108240450(rasa2)

ALIM:

106524371(rasa2)

NWH:	119411539(rasa2)

LTU:	140314457(rasa2)

MCEP:

125013490(rasa2)

AOCE:

111576997(rasa2)

EJA:	138197197(rasa2)

BFRE:

138634976(rasa2)

LCF:

108872403

CSEM:

103378579(rasa2)

POV:

109634418

SSEN:

122761291 122773851(rasa2)

SSOE:

131463083(rasa2)

HHIP:

117773375(rasa2)

HSP:	118106054(rasa2)

PPLT:

128439841(rasa2)

SMAU:

118298987(rasa2)

SDU:	111224060(rasa2)

SLAL:

111649986(rasa2)

XGL:	120792148(rasa2)

HCQ:	109525471(rasa2)

SSCV:

125972769(rasa2)

SBIA:

133505224(rasa2)

PTAO:

133482620(rasa2)

BPEC:

110174399(rasa2)

ENY:	140374989(rasa2)

MALB:

109970548(rasa2)

BSPL:

114867734(rasa2)

SJO:	128360857(rasa2)

SSCO:

133980159(rasa2)

TTY:	137185935(rasa2)

GMH:	115561362(rasa2)

SASA:

106580875(rasa2)

STRU:

115163204 115206149

OTW:	112265309 112266895

OMY:	110503738 110507611(rasa2)

OGO:	123992886 124004693

ONE:	115136912 115141685

OKI:	109905582 109909031

OKE:	118383491 118397315

OMM:	135546279 135552756

OCLA:

139383145 139386340

SALP:

111949342 111949550

SNH:	120018294 120028709

SFON:

129822061 129832198

CCLU:

121564516 121567541

ELS:	105012570(rasa2)

OEP:	134029520(rasa2)

SFM:	108932383(rasa2)

PKI:

111849521

AANG:

118210001(rasa2)

AROT:

135236968

CCOG:

133107674(rasa2)

LOC:	102698772(rasa2)

PSPA:

121323045 121327227

ARUT:

117417435

PSEX:

120533363(rasa2)

LCM:	102346776(RASA2)

CMK:	103179638(rasa2)

RTP:

109936745

CPLA:

122556231(rasa2)

CPUN:

140478675(rasa2)

HOC:	132821752(rasa2)

SCAU:

119975510(rasa2)

LERI:

129703297(rasa2)

HAKA:

140725672(rasa2)

» show all

Reference

PMID:16757315

Authors

Kupzig S, Bouyoucef D, Cozier GE, Cullen PJ

Title

Studying the spatial and temporal regulation of Ras GTPase-activating proteins.

Journal

Methods Enzymol 407:64-82 (2006)
DOI:10.1016/S0076-6879(05)07007-2

Reference

PMID:8917095

Authors

Kobayashi M, Masui T, Kusuda J, Kameoka Y, Hashimoto K, Iwashita S

Title

Human rasGTPase-activating protein (human counterpart of GAP1m): sequence of the cDNA, primary structure of the protein, production and chromosomal localization.

Journal

Gene 175:173-7 (1996)
DOI:10.1016/0378-1119(96)00144-8

Sequence

[hsa:5922]

LinkDB

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