KEGG ORTHOLOGY: K08063

ORTHOLOGY: K08063

Entry

K08063                      KO

Symbol

RFXAP

Name

regulatory factor X-associated protein

Pathway

map04612

Antigen processing and presentation

map05152

Tuberculosis

map05340

Primary immunodeficiency

Disease

H00985

Bare lymphocyte syndrome type2

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    K08063  RFXAP; regulatory factor X-associated protein
09160 Human Diseases
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K08063  RFXAP; regulatory factor X-associated protein
  09163 Immune disease
   05340 Primary immunodeficiency
    K08063  RFXAP; regulatory factor X-associated protein

Genes

HSA:	5994(RFXAP)

PTR:	100610983(RFXAP)

PPS:	100984854(RFXAP)

GGO:	101138043(RFXAP)

PON:	100450280(RFXAP)

NLE:	100582394(RFXAP)

MCC:	694441(RFXAP)

MCF:

102138204

CSAB:

103214283(RFXAP)

CATY:

105587865(RFXAP)

PANU:

101004422(RFXAP)

TGE:	112610875(RFXAP)

RRO:	104677939(RFXAP)

RBB:	108516591(RFXAP)

TFN:	117097323(RFXAP)

PTEH:

111540491(RFXAP)

CJC:	100393775(RFXAP)

SBQ:	101027776(RFXAP)

MMUR:

105862082(RFXAP)

OGA:	100944066(RFXAP)

MMU:	170767(Rfxap)

MCAL:

110291319(Rfxap)

MPAH:

110320546(Rfxap)

RNO:	499617(Rfxap)

MCOC:

116092874(Rfxap)

MUN:	110554912(Rfxap)

CGE:	100774659(Rfxap)

PLEU:

114695874

NGI:	103752221(Rfxap)

HGL:	101719989(Rfxap)

CPOC:

100717309(Rfxap)

CCAN:

109699608(Rfxap)

DORD:

105997133(Rfxap)

DSP:

122112884

NCAR:

124985544

OCU:	100338019(RFXAP)

OPI:

101530001

TUP:	102484630(RFXAP)

CFA:	607367(RFXAP)

VVP:	112918543(RFXAP)

VLG:

121497710

AML:	100475849(RFXAP)

UMR:	103664419(RFXAP)

UAH:	113251009(RFXAP)

UAR:

123791799

ELK:

111158537

LLV:

125095617

MPUF:

101691297(RFXAP)

ORO:	101375274(RFXAP)

EJU:	114209262(RFXAP)

ZCA:

113920434

MLX:	118009506(RFXAP)

FCA:	101088294(RFXAP)

PYU:

121012650

PBG:

122476973

PTG:	102967387(RFXAP)

PPAD:

109265816(RFXAP)

AJU:	106973843(RFXAP)

HHV:

120246209

BTA:	540760(RFXAP)

BIU:	109566774(RFXAP)

BBUB:

102412691

CHX:	102185753(RFXAP)

OAS:	105612445(RFXAP)

ODA:

120883112

CCAD:

122447069

SSC:	100155648(RFXAP)

CFR:	102520757(RFXAP)

CBAI:

105066308(RFXAP)

CDK:	105100832(RFXAP)

VPC:	102529776(RFXAP)

BACU:

103020095(RFXAP)

LVE:	103077390(RFXAP)

OOR:	101287764(RFXAP)

DLE:	111175071(RFXAP)

PCAD:

102974203(RFXAP)

PSIU:

116749884

EPZ:	103559383(RFXAP)

EAI:

106844942

MYB:	102243528(RFXAP) 106725997

MYD:	102753562(RFXAP)

MMYO:

118650050

MLF:	102428345(RFXAP)

MNA:	107525164(RFXAP)

PKL:

118728723

HAI:	109388472(RFXAP)

DRO:	112313590(RFXAP)

SHON:

AJM:

PDIC:

PHAS:

MMF:

RFQ:	117021063(RFXAP)

PALE:

102898769(RFXAP)

PGIG:

120610613

PVP:	105293314(RFXAP)

RAY:	107503949(RFXAP)

TOD:

119258530

SARA:

101539233(RFXAP)

LAV:	100658303(RFXAP)

TMU:

101345853

DNM:	101432051(RFXAP)

MDO:	100027231(RFXAP)

GAS:

123241257

SHR:	100920977(RFXAP)

PCW:	110195160(RFXAP)

OAA:

100080809

GGA:	418899(RFXAP)

PCOC:

116244162(RFXAP)

CJO:	107306771(RFXAP)

NMEL:

110402808(RFXAP)

AFUL:

116501334(RFXAP)

TGU:	101234225(RFXAP)

LSR:	110476700(RFXAP)

SCAN:

103812558(RFXAP)

PMOA:

120496306

OTC:

121337267

PRUF:

121353247

FAB:	101806274(RFXAP)

PMAJ:

107209746(RFXAP)

CCW:

104689928

ETL:	114060971(RFXAP)

TALA:

116959130

ACHC:

115353599

NPD:	112942882(RFXAP)

DNE:	112982142(RFXAP)

AMJ:	102570327(RFXAP)

CMY:

114022150

CPIC:

101937694

TST:	117871030(RFXAP)

CABI:

116839744(RFXAP)

MRV:

120401683

ACS:	103278417(rfxap)

PVT:	110074023(RFXAP)

SUND:

121926989

PBI:	103048639(RFXAP)

PMUR:

107287661(RFXAP)

TSR:	106545914(RFXAP)

PGUT:

117662136(RFXAP)

VKO:

123029553

PMUA:

114595806(RFXAP)

ZVI:	118085782(RFXAP)

GJA:	107106040(RFXAP)

STOW:

125432056

XLA:	108709940(rfxap.S)

XTR:	100379771(rfxap)

NPR:	108785355(RFXAP)

RTEM:

120929140

BBUF:

120996288

BGAR:

122931146

DRE:	100006212(rfxap)

SRX:	107728283 107728874 107734457(rfxap)

SANH:

107686162(rfxap) 107697413

SGH:	107578759 107589095

CCAR:

CAUA:

PPRM:

MAMB:

IPU:

PHYP:

113543604(rfxap)

SMEO:

124393606

TFD:

113638030

AMEX:

103039202(rfxap)

EEE:	113572180(rfxap)

TRU:	101075394(rfxap)

TNG:	GSTEN00018868G001

LCO:	104928218(rfxap)

NCC:	104964550(rfxap)

CGOB:

115019327(rfxap)

ELY:	117271275(rfxap)

PLEP:

121963486

SLUC:

116037130

ECRA:

117955437(rfxap)

PFLV:

114567182(rfxap)

GAT:

PPUG:

MSAM:

CUD:

MZE:	101471661(rfxap)

ONL:	100704569(rfxap)

OAU:

116311904

OLA:	101167388(rfxap)

OML:

112139895

XMA:	102218213(rfxap)

XCO:	114153306(rfxap)

XHE:	116728703(rfxap)

PRET:

103475560(rfxap)

PFOR:

103140050 103140107(rfxap)

PLAI:

106951405(rfxap)

PMEI:

106922235(rfxap)

GAF:

122844505

CVG:	107088285(rfxap)

CTUL:

119779216

GMU:

124876473

NFU:	107391187(rfxap)

KMR:

108236909

ALIM:

106514161(rfxap)

NWH:

119420563

AOCE:

111566079(rfxap)

CSEM:

103395221(rfxap) 103399480

POV:	109635807(rfxap)

SSEN:

122779557

HHIP:

117774126(rfxap)

LCF:	108893716(rfxap)

SDU:	111217127(rfxap)

SLAL:

111662677(rfxap)

XGL:

120802587

HCQ:	109515632(rfxap)

BPEC:

110158608(rfxap)

MALB:

109971886(rfxap)

SASA:

106563855(rfxap) 106604035

OTW:	112238481(rfxap) 112239533

OMY:	110510256 110533260

OGO:	123995231 124007444

ONE:	115123809 115125633

SALP:

112072828 112076117

SNH:	120021647 120056819

ELS:	105029978(rfxap)

SFM:	108936053(rfxap)

PKI:	111840452(rfxap)

AANG:

118236196(rfxap)

LOC:	102690257(rfxap)

PSPA:

121321372

ARUT:

117406047 117406921

LCM:	102346053(RFXAP)

CMK:

BFO:

BBEL:

SPU:

APLC:

SKO:

HAME:

PTRU:

PCAN:

GAE:

MYI:

PMAX:

MMER:

OSN:

DGT:

Reference

PMID:9118943

Authors

Durand B, Sperisen P, Emery P, Barras E, Zufferey M, Mach B, Reith W

Title

RFXAP, a novel subunit of the RFX DNA binding complex is mutated in MHC class II deficiency.

Journal

EMBO J 16:1045-55 (1997)
DOI:10.1093/emboj/16.5.1045

Sequence

[hsa:5994]

Reference

PMID:20024540

Authors

Bushway M, Cycon KA, Mulvaney K, Murphy SP

Title

Coordinate loss of MHC class II expression in the diffuse large B cell lymphoma cell line OCI-Ly2 is due to a novel mutation in RFX-AP.

Journal

Immunogenetics 62:109-16 (2010)
DOI:10.1007/s00251-009-0418-3

Sequence

[hsa:5994]

LinkDB

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