KEGG ORTHOLOGY: K08376

ORTHOLOGY: K08376

Entry

K08376                      KO

Symbol

NPSR1, GPR154

Name

neuropeptide S receptor

Pathway

map04080

Neuroactive ligand-receptor interaction

Disease

H00079

Asthma

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K08376  NPSR1, GPR154; neuropeptide S receptor
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K08376  NPSR1, GPR154; neuropeptide S receptor
G protein-coupled receptors [BR:ko04030]
Rhodopsin family
  Peptide
   Neuropeptide S
    K08376  NPSR1, GPR154; neuropeptide S receptor

Other DBs

GO:

0008188

Genes

HSA:	387129(NPSR1)

PTR:	747277(NPSR1)

PPS:	100977880(NPSR1)

GGO:	101128124(NPSR1)

PON:	100431510(NPSR1)

PPYG:

129041255(NPSR1)

NLE:	100605521(NPSR1)

HMH:	116812561(NPSR1)

SSYN:

129490047(NPSR1)

MCC:	574355(NPSR1)

MTHB:

126951418

MNI:	105475841(NPSR1)

CSAB:

103226238(NPSR1)

CATY:

105596598(NPSR1)

PANU:

101014723(NPSR1)

TGE:	112620557(NPSR1)

MLEU:

105534380(NPSR1)

RRO:	104675230(NPSR1)

RBB:	108517838(NPSR1)

TFN:	117073025(NPSR1)

PTEH:

111526136(NPSR1)

CANG:

105517575(NPSR1)

CJC:	100415735(NPSR1)

SBQ:	101033167(NPSR1)

CIMI:

108285204(NPSR1)

ANAN:

105723327(NPSR1)

CSYR:

103263873(NPSR1)

MMUR:

105859514

LCAT:

123646872(NPSR1)

PCOQ:

105805815(NPSR1)

OGA:	100966125(NPSR1)

MMU:	319239(Npsr1)

MCAL:

110301706(Npsr1)

MPAH:

110328172(Npsr1)

RNO:	300458(Npsr1)

MCOC:

116072599(Npsr1)

ASYL:

127689298(Npsr1)

MUN:	110564481(Npsr1)

CGE:	100765143(Npsr1)

MAUA:

101844047(Npsr1)

PROB:

127231394(Npsr1)

PLEU:

114695302(Npsr1)

MORG:

121451841(Npsr1)

MFOT:

126490172

AAMP:

119810434(Npsr1)

NGI:

103738029

CPOC:

100727393(Npsr1)

CCAN:

109685012(Npsr1)

DORD:

105999969(Npsr1)

DSP:	122120884(Npsr1)

PLOP:

125344799(Npsr1)

NCAR:

124991672

MMMA:

107146276(Npsr1)

ITI:	101969925(Npsr1)

OCU:	100301552(NPSR1)

OPI:	101526551(NPSR1)

TUP:	102500971(NPSR1)

GVR:	103606414(NPSR1)

CFA:	482394(NPSR1)

CLUD:

112670711(NPSR1)

VVP:	112935424(NPSR1)

VLG:	121474871(NPSR1)

NPO:	129502889(NPSR1)

AML:	100471187(NPSR1)

UMR:	103658969(NPSR1)

UAH:	113262649(NPSR1)

UAR:	123789572(NPSR1)

ELK:

111147403

LLV:

125080913

MNP:	132014982(NPSR1)

MLK:	131829608(NPSR1)

NVS:	122904087(NPSR1)

ORO:	101365281(NPSR1)

EJU:	114201308(NPSR1)

ZCA:	113911714(NPSR1)

NSU:	110589001(NPSR1)

FCA:	101093010(NPSR1)

PYU:	121028500(NPSR1)

PCOO:

112866709(NPSR1)

PBG:	122488088(NPSR1)

PVIV:

125161004(NPSR1)

LRUF:

124524876

LGF:	123606684(NPSR1)

AJU:

106968694

PTG:	102958053(NPSR1)

PPAD:

109248442(NPSR1)

PUC:

125930048

PLEZ:

122209727(NPSR1)

HHV:	120236379(NPSR1)

BTA:	519486(NPSR1)

BOM:	102285777(NPSR1)

BIU:	109557457(NPSR1)

BBIS:

104981890(NPSR1)

CHX:	102191673(NPSR1)

OAS:	101118180(NPSR1)

BTAX:

128046945(NPSR1)

CSUM:

138080335(NPSR1)

ODA:	120877520(NPSR1)

CCAD:

122438396(NPSR1)

MREE:

136170980(NPSR1)

OVR:	110134676(NPSR1)

MBEZ:

129552073(NPSR1)

SSC:	100217399(NPSR1)

CFR:	102521043(NPSR1)

CBAI:

105069290(NPSR1)

CDK:	105095866(NPSR1)

VPC:	102528419(NPSR1)

BACU:

103014207(NPSR1)

BMUS:

118900974(NPSR1)

LVE:	103080164(NPSR1)

OOR:

101282565

LALB:

132524322(NPSR1)

PCAD:

102979407(NPSR1)

PSIU:

116759142(NPSR1)

PPHC:

136127921(NPSR1)

NASI:

112403344(NPSR1)

ECB:	100055422(NPSR1)

EPZ:	103560932(NPSR1)

EAI:	106829576(NPSR1)

MYB:	102253688(NPSR1)

MYD:	102766407(NPSR1)

MMYO:

118665667(NPSR1)

MLF:	102424782(NPSR1)

MDT:	132211539(NPSR1)

MYUM:

139017038(NPSR1)

PKL:	118711387(NPSR1)

EFUS:

103291333(NPSR1)

MNA:	107544386(NPSR1)

DRO:	112306972(NPSR1)

SHON:

118983536(NPSR1)

AJM:	119035201(NPSR1)

PDIC:

114508110(NPSR1)

PHAS:

123811890(NPSR1)

MMF:	118620155(NPSR1)

PPAM:

129068840(NPSR1)

HAI:	109389810(NPSR1)

RFQ:	117012083(NPSR1)

PALE:

102891606(NPSR1)

PGIG:

120602440(NPSR1)

PVP:	105293669(NPSR1)

RAY:	107518542(NPSR1)

MJV:	108392853(NPSR1)

TOD:	119250078(NPSR1)

SARA:

101553596(NPSR1)

SFUM:

130027447(NPSR1)

SETR:

126020304(NPSR1)

LAV:	100662369(NPSR1)

TMU:

101344155

ETF:	101653567(NPSR1)

DNM:	101411579(NPSR1)

MDO:	100011626(NPSR1)

GAS:	123246837(NPSR1)

SHR:	100918868(NPSR1)

AFZ:

127550450

PCW:	110196024(NPSR1)

TVP:	118831874(NPSR1)

PBRV:

138158456(NPSR1)

OAA:	120638013(NPSR1)

GGA:	428462(NPSR1)

PCOC:

116226987(NPSR1)

MGP:	100549933(NPSR1)

CJO:	107309873(NPSR1)

TPAI:

128085399(NPSR1)

LMUT:

125695819(NPSR1)

NMEL:

110394709(NPSR1)

APLA:

101796597(NPSR1)

ACYG:

106048379 136786338

CATA:

118250888(NPSR1)

AFUL:

116486411(NPSR1)

TGU:	100231248(NPSR1)

LSR:	110483377(NPSR1)

SCAN:

103821169(NPSR1)

PMOA:

120505026(NPSR1)

OTC:	121337647(NPSR1)

PRUF:

121353066(NPSR1)

ATRC:

139591240(NPSR1)

GFR:	102034848(NPSR1)

FAB:	101820205(NPSR1)

OMA:	130249660(NPSR1)

PHI:	102100468(NPSR1)

PMAJ:

107215723(NPSR1)

CCAE:

111923601(NPSR1)

CCW:	104688953(NPSR1)

CBRC:

103615853(NPSR1)

ACOE:

138106649(NPSR1)

ETL:	114061734(NPSR1)

ZAB:	102065945(NPSR1)

ZLE:	135443136(NPSR1)

ACHL:

103808613(NPSR1)

SVG:	106859547(NPSR1)

MMEA:

130574457(NPSR1)

HRT:	120756485(NPSR1)

SATI:

136366428(NPSR1)

CCIC:

134046587(NPSR1)

FPG:	101915349(NPSR1)

FCH:	102046669(NPSR1)

CCRI:

104168263(NPSR1)

NNT:	104406741(NPSR1)

SHAB:

115609678(NPSR1)

ACUN:

113477544(NPSR1)

TALA:

104365491(NPSR1)

ACHC:

115339887(NPSR1)

HALD:

104315365(NPSR1)

HLE:	104841273(NPSR1)

AGEN:

126045334

HHAR:

128144216(NPSR1)

GCL:

127029967

CSTI:

104559954(NPSR1)

LDI:	104350822(NPSR1)

MNB:	103776270(NPSR1)

DPUB:

104299666(NPSR1)

PPUS:

135189495(NPSR1)

AVIT:

104272453(NPSR1)

BRHI:

104499258(NPSR1)

EGZ:	104123091(NPSR1)

NNI:	104012141(NPSR1)

PCRI:

104031482(NPSR1)

PCAO:

104048279(NPSR1)

PADL:

103923983(NPSR1)

AFOR:

103894167(NPSR1)

GSTE:

104260948(NPSR1)

CBOY:

140647050(NPSR1)

CLV:	102098966(NPSR1)

CNIC:

135985855(NPSR1)

MUI:	104539960(NPSR1)

PGUU:

104465030(NPSR1)

PLET:

104624380(NPSR1)

EHS:	104512283(NPSR1)

CMAC:

104478929(NPSR1)

CUCA:

104065386(NPSR1)

TEO:	104379970(NPSR1)

BREG:

104634104(NPSR1)

OHA:	104328668(NPSR1)

ACAR:

104527836(NPSR1)

CPEA:

104395619(NPSR1)

CVF:	104287492(NPSR1)

RTD:	128905647(NPSR1)

CRID:

134510641(NPSR1)

AAM:	106489005(NPSR1)

AROW:

112974512(NPSR1)

NPD:	112958477(NPSR1)

DNE:	112984338(NPSR1)

SCAM:

104147246(NPSR1)

ASN:	102382223(NPSR1)

AMJ:	102567775(NPSR1)

CPOO:

109312467(NPSR1)

GGN:	109291838(NPSR1)

PSS:	102446362(NPSR1)

CMY:	102935468(NPSR1)

CCAY:

125631027(NPSR1)

DCC:	119850667(NPSR1)

CPIC:

101953469(NPSR1)

TST:	117872561(NPSR1)

CABI:

116823850(NPSR1)

MRV:	120396543(NPSR1)

ACS:	100558091(npsr1)

ASAO:

132778560(NPSR1)

PVT:	110076216(NPSR1)

SUND:

121934584(NPSR1)

PBI:	103051919(NPSR1)

PMUR:

107283815(NPSR1)

CTIG:

120305050(NPSR1)

VKO:	123017661(NPSR1)

PMUA:

114607811(NPSR1)

PRAF:

128423931(NPSR1)

ZVI:	118092000(NPSR1)

HCG:	128331736(NPSR1)

GJA:	107119910(NPSR1)

STOW:

125440596(NPSR1)

EMC:	129337897(NPSR1)

XLA:	108718506(npsr1.L)

XTR:	100490145(npsr1)

NPR:	108799467(NPSR1)

RTEM:

120940377(NPSR1)

ACAT:

141144619(NPSR1)

BBUF:

121001824(NPSR1)

BGAR:

122938667(NPSR1)

DTC:	141052698(NPSR1)

PWL:	138260039(NPSR1)

GSH:	117354898(NPSR1)

PSPA:

121308912

ARUT:

117400066

PMRN:

116945279(NPSR1)

LRJ:	133344508(NPSR1)

BFO:	118406038 118406039 118406040 118415193 118416469 118416680

BBEL:

109461671 109461672 109469005

SPU:	100891879 593532

LPIC:

129263207

AJJ:	139964820 139979808

APLC:

110989444 110989500 110989505 110991060

ARUN:

117291282

AAMU:

139939875

AFIL:

140155079

SKO:	100367563 100368831 100370632

PFLL:

139129414 139134105 139143493

DME:	Dmel_CG33344(CCAP-R)

DER:

6554529

DSE:

6616993

DSI:	Dsimw501_GD18159(Dsim_GD18159)

DYA:	Dyak_GE10655

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI22912

DAZ:

108608822

DNV:

108650563

DHE:

111602957

DVI:	6630863(CCAP-R)

CCAT:

BOD:

BDR:

RZE:

AOQ:

ALUD:

TDA:

SCAC:

LCQ:

LSQ:

CVJ:	135948810(CCAP-R)

GFS:

119639262

CLON:

129607895

HIS:

119660055

AGA:	1281161 1281162

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

AALI:

ACOS:

AAG:	5570884 5570885

AALB:

109429217 109429221 115261363

ASUA:

134220218 134220474

CQU:	CpipJ_CPIJ006268 CpipJ_CPIJ006269

CPII:

CBRI:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

COBS:

139112524(Ccap-r)

TLN:	139811484(Ccap-r)

HST:

DQU:

CFO:

FEX:

PMEC:

138934040(Ccap-r)

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:	124408597 124415974

NPT:	124216846(CCAP-R) 124219195

NFB:	124179822 124180746

NLO:	107221513 107224534

NVG:	124302619 124309812

AROA:

105691555 105692762

TCA:	657291(Ccapr1) 658661(Ccapr2)

TMOL:

138131801 138138443(CCAP-R)

DPA:

109539022

ESIM:

136408007

EFOR:

136340042

SOY:	115874248 115883009

AGRG:

126744713

ATD:	109596064 109596710

CSET:

123312164 123317126

HAXR:

123679158 123681630

AGB:	108909132 108909662 108915298

LDC:	111509980 111512594

DVV:	114333048 114345196

NVL:	108556964 108565856

DCOR:

APLN:

PPYR:

OTU:

BMOR:

100174937(NGR-A26) 100187570(NGR-A30)

BMAN:

114240139 114240157

MSEX:

115445675 115445677

DPL:	KGM_211411 KGM_211412

BANY:

112045191 112045230

MJU:	123866652 123866687

NIQ:	126768344 126768518

VCD:	124530314 124530501

MCIX:

123654407 123654756

PMAC:

106714461 106714464

PPOT:

106100127 106100230

PXU:	106125053 106125557

BPHI:

137930848 137930894

PRAP:

110991959 110991966

PBX:	123711830 123712502

PNAP:

125056763 125056788

ZCE:	119831152 119831227

CCRC:

123692705 123692779

LSIN:

126976627 126976712

AAGE:

121731245 121731258

HAW:	110380985 126055992

HZE:	124630472 124630777

TNL:

113495316

SLIU:

111349449 111349689

OFU:	114353083 114362173

ONU:	135088525 135088534

ATRA:

106130192 106130232

GMW:	113511665 113511804

PXY:	105382736 105382770

PGW:	126366622 126366674

LGLY:

CSTB:

CFUM:

CCRN:

API:	100168813 100574733

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

106666320 106666691 106671967

HHAL:

106684547 106692632

NLU:	111047856 111049072 111057823

HVI:	124355482 124356742 124365597

MQU:	128986946 128999692 129000081

PHU:	Phum_PHUM157220

FOC:	113215641 113218464

TPAL:

117639917 117643322

ZNE:	110830897 110831394

CSEC:

111866215 111874293

PAME:

138702920 138709978 138710585

SGRE:

BROR:

IEL:

HAMR:

FCD:

DPX:	DAPPUDRAFT_317355

DMK:

DPZ:

AFRA:

PVM:

PJA:

PCHN:

PMOO:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

MRJ:

PORN:

HAZT:

EAF:

LSM:

TCF:

PPOI:

DSV:	119450387 119453749

RSAN:

119381628 119398829

RMP:	119169659 119185792 119186402 119186547

VDE:

111251071

VJA:

111265359

GOE:

100898773

TUT:	107359249 107369900 107370560

CSCU:

111634505

CVS:

136983212

PTEP:

107450078 107450080 107452809

ABRU:

129959639 129960963 129984594

UDV:	129221008 129225542 129234310

SDM:	118191112 118193914 118196241

LPOL:

106458727 106458737 106461175 106461185 106462984 106471947 106475350 106476019 106478530

PMEO:

129584027

HRO:	HELRODRAFT_162671 HELRODRAFT_68919 HELRODRAFT_71528 HELRODRAFT_77874

LGI:	LOTGIDRAFT_126859 LOTGIDRAFT_139356 LOTGIDRAFT_226790 LOTGIDRAFT_65275 LOTGIDRAFT_94997

PVUL:

126807685 126832685 126832690

PCAN:

112557989 112559885 112572197 112574574 112575117

LSAX:

138956559 138959915 138960401 138960473

BGT:	106057845 106079581

GAE:	121381444 121387295 121387625

HRF:	124112281 124118417 124138181 124149182 124149209 124149523 124149860 124152236

HRJ:	124253226 124256328 124256375 124256379 124256381 124256382 124264752 124269108 124278100 124278373 124285684 124292169

HASI:

137257665 137258785 137261666 137277886 137297881 137298321 137298350 137298691

HCRA:

139453960 139457595 139457628 139463353 139463362 139463400 139465214 139466763

CRG:	105317344 105320998 105321693 105331305 105335250 105336620 105340891 105347703 136274730 136274731

CANU:

128155273 128155869 128155871 128157404 128170533 128189750 128191192

CVN:	111105911 111119377 111122556 111122913 111123376 111123471 111123870 111124959 111126938

OED:	125645637 125647304 125680171 125681666 125682474 125683269 130051695 130051764

MYI:	110445762 110445811 110448307 110448973 110449698 110450774 110459755 110459966 110460526 110461587

PMAX:

117316095 117316097 117316317 117316792 117317465 117317814 117317877 117317971 117317974 117318103 117318157 117323502 117328897 117336729 117338429

AIRR:

138309076 138310045 138310139 138310141 138310300 138310311 138310644 138310652 138310676 138326767 138328842

MCAF:

127717932 127718149

MMER:

123536210 123536550 123536802 123538059 123538826 123539375 123545589

RPHI:

132718544 132720948 132723515 132724430 132728183 132729447 132729449 132730154 132730710 132730711 132731193 132731372 132742915 132744902 132745739 132749065

DPOL:

127839589 127849153 127856386 127856975 127858737 127858847 127858915 127859783 127868377 127868378

MAEA:

128203123 128203131 128203208 128203492 128230269 128230909 128232280 128232881 128232988 128240447 128240855 128241247 128241248 128241277 128241278 128241881

OBI:	106868179 106869641 106875206 106876599 106877248

OSN:	115209607 115217118 115223665 115226896 115230244

LJP:	135464359 135464893 135468444

LAK:

106156922

SMM:	Smp_199690

SHX:	MS3_00007782(AVPR1A)

OVI:	T265_00777

EGL:	EGR_01723 EGR_01724

LLON:

135488251 135492740 135497954 135500025

ATEN:

XEN:

HSY:

Reference

PMID:15073379

Authors

Laitinen T, Polvi A, Rydman P, Vendelin J, Pulkkinen V, Salmikangas P, Makela S, Rehn M, Pirskanen A, Rautanen A, Zucchelli M, Gullsten H, Leino M, Alenius H, Petays T, Haahtela T, Laitinen A, Laprise C, Hudson TJ, Laitinen LA, Kere J

Title

Characterization of a common susceptibility locus for asthma-related traits.

Journal

Science 304:300-4 (2004)
DOI:10.1126/science.1090010

Sequence

[hsa:387129]

LinkDB

DBGET integrated database retrieval system