KEGG ORTHOLOGY: K08469

ORTHOLOGY: K08469

Entry

K08469                      KO

Symbol

GPR158

Name

G protein-coupled receptor 158

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K08469  GPR158; G protein-coupled receptor 158
G protein-coupled receptors [BR:ko04030]
Metabotropic glutamate receptor family
  Unclassified GPCRs
   K08469  GPR158; G protein-coupled receptor 158

Genes

HSA:	57512(GPR158)

PTR:	466025(GPR158)

PPS:	100989843(GPR158)

GGO:	101140947(GPR158)

PON:	100437045(GPR158)

PPYG:

129045160(GPR158)

NLE:	100596875(GPR158)

HMH:	116462445(GPR158)

SSYN:

129480740(GPR158)

MCC:	707065(GPR158)

MCF:	102125682(GPR158)

MTHB:

126962996

MNI:	105480013(GPR158)

CSAB:

103238020(GPR158)

CATY:

105583773(GPR158)

PANU:

116273405

TGE:	112631963(GPR158)

MLEU:

105555202(GPR158)

RRO:	104666851(GPR158)

RBB:	108528818(GPR158)

TFN:	117082341(GPR158)

PTEH:

111550028(GPR158)

CANG:

105527502(GPR158)

CJC:	100391108(GPR158)

SBQ:

101033395

CIMI:

108309277(GPR158)

ANAN:

105715729(GPR158)

CSYR:

103260220(GPR158)

MMUR:

105878121(GPR158)

LCAT:

123626194(GPR158)

PCOQ:

105818767(GPR158)

OGA:	100965925(GPR158)

MMU:	241263(Gpr158)

MCAL:

110286171(Gpr158)

MPAH:

110319276(Gpr158)

RNO:	291352(Gpr158)

MCOC:

116089762(Gpr158)

ANU:

117713416

ASYL:

127664735(Gpr158)

MUN:	110540986(Gpr158)

CGE:	100757301(Gpr158)

MAUA:

101836395(Gpr158)

PROB:

127237413(Gpr158)

PLEU:

114708618(Gpr158)

MORG:

121440732(Gpr158)

MFOT:

126507831

AAMP:

119816778(Gpr158)

NGI:	103732995(Gpr158)

HGL:	101700121(Gpr158)

CPOC:

100735424(Gpr158)

CCAN:

109703406

DORD:

105984465(Gpr158)

DSP:	122113174(Gpr158)

PLOP:

125367186(Gpr158)

NCAR:

124962059

MMMA:

107150249(Gpr158)

ITI:	101960255(Gpr158)

OCU:

100356312

OPI:	101519442(GPR158)

TUP:	102501570(GPR158)

GVR:	103596577(GPR158)

CFA:	477984(GPR158)

CLUD:

112670302(GPR158)

VVP:	112931162(GPR158)

VLG:	121496549(GPR158)

NPO:	129513908(GPR158)

AML:	100470978(GPR158)

UMR:	103680148(GPR158)

UAH:	113241324(GPR158)

UAR:	123778153(GPR158)

ELK:

111155597

LLV:

125107150

MPUF:

101688873(GPR158)

MNP:	132020085(GPR158)

MLK:	131838149(GPR158)

NVS:	122891696(GPR158)

ORO:	101369320(GPR158)

EJU:	114217267(GPR158)

ZCA:	113921460(GPR158)

MLX:	118026580(GPR158)

NSU:	110577737(GPR158)

LWW:

102750632

FCA:	101086730(GPR158)

PYU:	121014699(GPR158)

PCOO:

112867723(GPR158)

PBG:	122473716(GPR158)

PVIV:

125169459(GPR158)

LRUF:

124501092

LGF:	123589931(GPR158)

AJU:

106969762

PTG:	102970522(GPR158)

PPAD:

109256887(GPR158)

PUC:

125918648

PLEZ:

122223985(GPR158)

HHV:

120223571

BTA:	538123(GPR158)

BIU:	109567792(GPR158)

BBUB:

102399322(GPR158)

BBIS:

105003016(GPR158)

CHX:	102172168(GPR158)

OAS:	101106191(GPR158)

BTAX:

128058775(GPR158)

CSUM:

138091858(GPR158)

ODA:	120869303(GPR158)

CCAD:

122448786(GPR158)

MREE:

136157802(GPR158)

OVR:	110149267(GPR158)

MBEZ:

129557879(GPR158)

SSC:	100622098(GPR158)

CFR:	102507987(GPR158)

CBAI:

105076845(GPR158)

CDK:	105102068(GPR158)

VPC:	102544151(GPR158)

BACU:

102997166(GPR158)

BMUS:

118888647(GPR158)

LVE:	103086397(GPR158)

OOR:	101274621(GPR158)

LALB:

132526981(GPR158)

DLE:	111178068(GPR158)

PCAD:

102973560(GPR158)

PSIU:

116749347(GPR158)

NASI:

112413959(GPR158)

ECB:	100055544(GPR158)

EPZ:	103552652(GPR158)

EAI:	106835266(GPR158)

MYB:	102242745(GPR158)

MYD:	102763440(GPR158)

MMYO:

118673719(GPR158)

MLF:	102439468(GPR158)

MDT:	132214185(GPR158)

MYUM:

139022002(GPR158)

PKL:	118731546(GPR158)

EFUS:

103292613(GPR158)

MNA:	107546334(GPR158)

DRO:	112318715(GPR158)

SHON:

118980547(GPR158)

AJM:	119034698(GPR158)

PDIC:

114492383(GPR158)

PHAS:

123831321(GPR158)

MMF:	118643543(GPR158)

PPAM:

129086025(GPR158)

HAI:	109375428(GPR158)

RFQ:	117019216(GPR158)

PALE:

102886218(GPR158)

PGIG:

120614684(GPR158)

PVP:	105299332(GPR158)

RAY:	107500088(GPR158)

MJV:	108405485(GPR158)

TOD:	119244763(GPR158)

SARA:

101558047(GPR158)

SFUM:

130039226(GPR158)

SETR:

126014455(GPR158)

LAV:	100667961(GPR158)

TMU:

101343878

ETF:	101657069(GPR158)

DNM:	101442277(GPR158)

MDO:	100025150(GPR158)

GAS:	123249202(GPR158)

SHR:	100923887(GPR158)

AFZ:

127564025

PCW:	110202188(GPR158)

PBRV:

138159952(GPR158)

OAA:	100074918(GPR158)

TACU:

119936241(GPR158)

GGA:	100859400(GPR158)

PCOC:

116243190(GPR158)

MGP:

104911386

CJO:	107308976(GPR158)

TPAI:

128086544(GPR158)

LMUT:

125695911(GPR158)

NMEL:

110394143(GPR158)

APLA:

101793697(GPR158)

ACYG:

106048105(GPR158)

CATA:

118247439(GPR158)

AFUL:

116486403(GPR158)

TGU:	100229682(GPR158)

LSR:	110471987(GPR158)

SCAN:

103813090(GPR158)

PMOA:

120503530(GPR158)

OTC:	121338122(GPR158)

PRUF:

121364782(GPR158)

ATRC:

139590890(GPR158)

GFR:	102037438(GPR158)

FAB:	101809105(GPR158)

OMA:	130249006(GPR158)

PHI:	102102926(GPR158)

PMAJ:

107200920(GPR158)

CCAE:

111924374

CCW:	104689361(GPR158)

CBRC:

103620653(GPR158)

ACOE:

138106276(GPR158)

ETL:	114060317(GPR158)

ZAB:	102074138(GPR158)

ZLE:	135443649(GPR158)

ACHL:

103809716(GPR158)

SVG:	106856685(GPR158)

MMEA:

130584211(GPR158)

HRT:	120757768(GPR158)

SATI:

136359405(GPR158)

CCIC:

134044818(GPR158)

FPG:	101917912(GPR158)

FCH:	102056744(GPR158)

CCRI:

104165396(GPR158)

NNT:	104407042(GPR158)

SHAB:

115615381(GPR158)

ACUN:

113476832(GPR158)

TALA:

104360312(GPR158)

ACHC:

115339663(GPR158)

HLE:	104840891(GPR158)

AGEN:

126037871

HHAR:

128149375(GPR158)

GCL:

127013181

CSTI:

104550880(GPR158)

LDI:	104353869(GPR158)

DPUB:

104299211(GPR158)

PPUS:

135185616(GPR158)

AVIT:

104272110(GPR158)

BRHI:

104500318(GPR158)

EGZ:	104122425(GPR158)

NNI:	104016224(GPR158)

PCRI:

104029692(GPR158)

PADL:

103922477(GPR158)

AFOR:

103895605(GPR158)

GSTE:

104253395(GPR158)

CBOY:

140648462(GPR158)

CLV:

102087247

PGUU:

104469493(GPR158)

PLET:

104614618(GPR158)

CMAC:

104485818(GPR158)

CUCA:

104066686(GPR158)

TEO:	104378869(GPR158)

BREG:

104634163(GPR158)

OHA:	104339282(GPR158)

CPEA:

104397092(GPR158)

CVF:	104288362(GPR158)

RTD:	128905708(GPR158)

CRID:

134511130(GPR158)

AAM:	106489939(GPR158)

AROW:

112966079(GPR158)

NPD:	112952030(GPR158)

TGT:

104573988

DNE:	112984047(GPR158)

SCAM:

104147225(GPR158)

ASN:	102384200(GPR158)

AMJ:	102560272(GPR158)

CPOO:

109307781(GPR158)

GGN:	109291094(GPR158)

PSS:	102449985(GPR158)

CMY:	102938245(GPR158)

CCAY:

125631332(GPR158)

DCC:	119852281(GPR158)

CPIC:

101945865(GPR158)

TST:	117872118(GPR158)

CABI:

116822077(GPR158)

MRV:	120396352(GPR158)

ACS:	100566037(gpr158)

ASAO:

132778918(GPR158)

PVT:	110083203(GPR158)

SUND:

121935730(GPR158)

PBI:	103065738(GPR158)

PMUR:

107282836(GPR158)

CTIG:

120314519(GPR158)

TSR:	106538550(GPR158)

PGUT:

117655065(GPR158)

APRI:

131198269(GPR158)

PTEX:

113442474(GPR158)

NSS:	113414963(GPR158)

VKO:	123020835(GPR158)

PMUA:

114607404(GPR158)

PRAF:

128424075(GPR158)

ZVI:	118091974(GPR158)

HCG:	128330449(GPR158)

GJA:	107113051(GPR158)

STOW:

125440799(GPR158)

EMC:	129337943(GPR158)

XLA:	108718787(gpr158.L)

XTR:	779597(gpr158)

NPR:	108788213(GPR158)

RTEM:

120940014(GPR158)

BBUF:

121002605(GPR158)

BGAR:

122938995(GPR158)

PWL:	138261851(GPR158)

MUO:	115468934(GPR158)

GSH:	117354927(GPR158)

DRE:	568637(gpr158b) 570001(gpr158a)

SRX:	107709775 107711710 107727549 107758367

SANH:

107661898 107671743 107675282 107687544

SGH:	107558004 107570048 107588021 107593759

CCAR:

109058800 109077568(gpr158a) 109099048

CAUA:

113038786 113042158 113046090 113065998

CGIB:

127946374 127950425 128012811 128025067

PTET:

122330093(gpr158a) 122360528(gpr158b)

LROH:

127155654(gpr158a) 127176619(gpr158b)

OMC:	131527783(gpr158b) 131532836(gpr158a)

PPRM:

120475860(gpr158a) 120482841(gpr158b)

RKG:	130084425(gpr158a) 130096407(gpr158b)

MAMB:

125251268(gpr158b) 125257697(gpr158a)

CIDE:

127499326 127505685 127506301

CERY:

137002798(gpr158b) 137013582(gpr158a)

MASI:

127431845 127434233 127441626 127442648

TROS:

130546948(gpr158a)

TDW:	130413664(gpr158a) 130417776(gpr158b)

MANU:

129425863(gpr158a) 129443404(gpr158b)

PDAB:

135747937(gpr158b) 135785284(gpr158a)

IPU:	108268005(gpr158b) 108278990(gpr158a)

IFU:	128605282(gpr158a) 128609786(gpr158b)

PHYP:

113540605 113545495(gpr158)

SMEO:

124384540(gpr158a) 124387747(gpr158b)

TFD:	113647117(gpr158b) 113651254(gpr158a)

TVC:	132845512(gpr158a) 132848198(gpr158b) 132852811(gpr179)

CGAR:

128520319(gpr158a) 128526537(gpr158b)

NGRA:

132887142(gpr158a) 132890843(gpr158b) 132899036(gpr179)

TRN:	134310425(gpr158a) 134312089(gpr158b)

AMEX:

103025251(gpr158a) 103042593(gpr158b)

CMAO:

118812967(gpr158a) 118826089(gpr158b)

EEE:	113570069 113589799

CHAR:

105889231(gpr158a) 105891311(gpr158b)

SPIL:

134066521(gpr158a) 134099124(gpr158b)

TRU:	101073410 101078386

TFS:	130514312(gpr158a) 130538890(gpr158b)

TNG:	GSTEN00025500G001

LCO:	104933964(gpr158) 104934157

NCC:	104942394(gpr158) 104963727

TBEN:

117488378 117497372(gpr158a)

CGOB:

115023109 115025681(gpr158)

PGEO:

117461725(gpr158b) 117465945(gpr158a)

GACU:

117544726(gpr158a) 117545536

EMAC:

134866253 134883840(gpr158a)

ELY:	117264789(gpr158a) 117271438

EFO:	125881878(gpr158a) 125901564

PLEP:

121960690(gpr158a)

SLUC:

116048564(gpr158a) 116065082

ECRA:

117937814(gpr158a) 117954496

ESP:	116672142(gpr158) 116698751

PFLV:

114549615(gpr158) 114565991

GAT:	120811585(gpr158a) 120816019(gpr158b) 120825442(gpr179)

PPUG:

119198487(gpr158a) 119209108(gpr158b)

AFB:	129089220 129111001(gpr158a)

CLUM:

117746821 117749851(gpr158a)

PSWI:

130198334(gpr158b) 130206295(gpr158a)

CANA:

137782002 137788695(gpr158a)

CVE:	137866067 137872097(gpr158a)

MSAM:

119902427 119912377(gpr158a)

SCHU:

122866559(gpr158a) 122886477

CUD:	121520660 121527558(gpr158a)

SPUL:

138596047(gpr158a) 138612084

LMIX:

132978320(gpr158b) 132994014(gpr158a)

ALAT:

119009011(gpr158a) 119010972

ASTR:

137587764(gpr158a)

MZE:	101467583(gpr158) 101472395

ONL:	100690086(gpr158) 100697448

OAU:	116324985(gpr158a) 116335240

OLA:	101168242 101171369(gpr158)

OML:	112147487(gpr158b) 112151247(gpr158a)

CSAI:

133423555(gpr158a) 133453114

XMA:	102216929 102231078(gpr158)

XCO:	114137177(gpr158) 114146817

XHE:	116712066(gpr158) 116722116

PRET:

103456768(gpr158) 103478952

PFOR:

103129206 103140552(gpr158)

PLAI:

106951036(gpr158) 106961867

PMEI:

106920781(gpr158) 106928301

GAF:	122823941(gpr158a) 122840651(gpr158b)

PPRL:

129352096(gpr158a) 129362059

CVG:	107081827(gpr158) 107086803

CTUL:

119779285(gpr158b) 119787315(gpr158a)

GMU:	124858012(gpr158a) 124870217

NFU:	107383047(gpr158) 107384307

KMR:	108230250(gpr158a) 108238340

ALIM:

106513785 106515544(gpr158) 106526799

NWH:	119414934(gpr158b) 119429509

AOCE:

111584072(gpr158a) 111588111

EJA:	138204454(gpr158a) 138207302

BFRE:

138619748(gpr158a) 138632554

MCEP:

124995909(gpr158a) 125011389

CSEM:

103377339(gpr158) 103396263

POV:	109639609 109642636

SSEN:

122768749(gpr158a) 122774611

SSOE:

131466907 131470841(gpr158a)

HHIP:

117754170(gpr158a) 117778649(gpr158b)

HSP:	118098245(gpr158a) 118117224(gpr158b)

PPLT:

128425927(gpr158a) 128455218(gpr158b)

SMAU:

118291477(gpr158a) 118311518

LCF:	108883868 108900028(gpr158a)

SDU:	111224341(gpr158) 111228893

SLAL:

111666476 111673667(gpr158)

XGL:	120790047(gpr158a) 120798486

HCQ:	109520549 109524718

SSCV:

125984812 125985815

SBIA:

133493056(gpr158a) 133510918

PEE:	133396291(gpr158a) 133412102(gpr158b)

PTAO:

133470353 133488445

BPEC:

110165548(gpr158) 110173432

ENY:	140356266 140372489 140372512

MALB:

109961379(gpr158) 109974042

BSPL:

114844614 114853244(gpr158a)

SJO:	128369353 128382504(gpr158a)

SSCO:

133990906(gpr158b) 134002391(gpr158a)

GMH:	115537467(gpr158) 115549367

SASA:

106568695 106590224(gpr158) 106598107

STRU:

115156600 115170141 115195693(gpr158)

OTW:	112227230 112245372(gpr158a) 112260250

OMY:	110489851(gpr158a) 110509081 110529996(gpr158b)

OGO:	124009624 124039715(gpr158a) 124042141

ONE:	115114097 115115260 115130295

OKI:	109871922 109875129 109899034(gpr158)

OKE:	118372365(gpr158a) 118373446 118402296

OMM:	135516526 135517402(gpr158a) 135558381

OCLA:

139366753 139375831 139387445

SALP:

111953927(gpr158) 111956330 111979703

SNH:	120019942 120050665(gpr158a) 120056238

CCLU:

121534929 121569374(gpr158a) 121581639 123492385

ELS:

105024993

OEP:	134035155(gpr158a) 134036606

SFM:	108927647(gpr158) 108937586 114910914

PKI:	111845979 111850016(gpr158)

AANG:

118226110(gpr158a) 118233005

AROT:

135253336(gpr158a) 135260522

CCOG:

133121217(gpr179) 133125772(gpr158a) 133136344

LOC:	102685333(gpr158)

PSPA:

ARUT:

PSEX:

LCM:

CMK:	103176275(gpr158a)

RTP:	109938098(gpr158a)

CPLA:

122539765(gpr179) 122550046(gpr158a)

HOC:	132816123(gpr158a) 132830953(gpr179)

LERI:

129707312(gpr158a) 129710106(gpr179)

PMRN:

116937591

LRJ:	133346200(GPR158)

BFO:	118406091 118418630

BBEL:

109465345 109473334

SPU:	100888258 105437963 105446187

AJJ:	139963360 139963505 139964561

APLC:

110986111 110988263 110990225

ARUN:

117289149

AAMU:

139934804 139934825 139939646

AFIL:

140135411 140135728 140135903 140146224 140152833

SKO:	100371428 100375075

PFLL:

139143709 139148129 139148132

DME:	Dmel_CG43795(CG43795)

DER:

6547796

DSE:

6615720

DSI:	Dsimw501_GD11766(Dsim_GD11766)

DYA:	Dyak_GE14293

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI20516

DAZ:

DNV:

DHE:

CCAT:

BOD:

BDR:

RZE:	108361963 108366532

AOQ:

ALUD:

TDA:

SCAC:

LCQ:

LSQ:	119608479 119608983

CVJ:

GFS:

ECOE:

CLON:

HIS:

AGA:	1276821 1279347

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

AALI:

ACOS:

131264040 131265228 131265230

AAG:	23687899 5579463

AALB:

109410186 109423655 115265106

ASUA:

134211567 134212819

CQU:	CpipJ_CPIJ000002

CPII:

CBRI:

CNS:

BCOO:

LLL:	129789532 129791656

PPAP:

AME:

ACER:

ALAB:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:	105153594 105154229

ACEP:

105622242

PBAR:

105425044 105432882

VEM:	105564424 105566603

COBS:

139109070

TLN:

139813853

HST:

105190537

DQU:	106744491 106746728 106750517

CFO:	105252833 105258716

FEX:

115240265

PMEC:

138935208

LHU:	105667584 105675332

PGC:

OBO:

PCF:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

AROA:

TCA:

TMOL:

DPA:

ESIM:

EFOR:

SOY:

AGRG:

ATD:

CSET:

HAXR:

AGB:

NVL:	108559769 108563856

APLN:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_205549

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CSTB:

API:	100165101 100166910 100168979 100569647

DNX:	107165215 107169935 107170002

AGS:	114124795 114126333 114126334 114132014

RMD:	113551217 113556938 113560964 113561116

ACOO:

126846329 126846805

DVT:	126895498 126895500

BTAB:

CLEC:

NLU:

HVI:

MQU:

PHU:	Phum_PHUM404600

FOC:	113202207 113202891 113210928

TPAL:

117642228 117642991 117643032

ZNE:

CSEC:

PAME:

BROR:

IEL:

HAMR:

FCD:

DPX:	DAPPUDRAFT_46663

DMK:

AFRA:

PJA:

PMOO:

PCLA:

PTRU:

MNZ:

MRJ:

PORN:

HAZT:

EAF:

LSM:

TCF:

LGI:	LOTGIDRAFT_127003 LOTGIDRAFT_161509

PCAN:

112570939 112577171

LSAX:

138953229

GAE:	121371693 121389383

HRF:	124135293 124151499

HRJ:	124261060 124266361

HASI:

137257672 137294651

HCRA:

139442507 139446204

CRG:	105329680 105337852 109617686

CANU:

128188527

CVN:

111134050

OED:

125668564

MYI:	110450498 110463414

PMAX:

AIRR:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:	106876327 106877599

OSN:	115216514 118763956

LJP:	135467350 135475060

LAK:	106163714 106166534

LLON:

135485116 135496267

NVE:	116614471 116614472 5518444

EPA:	110232550 110238675 110238729

ATEN:

116289290 116289301 116297637

ADF:

107334615

AMIL:

114965108 114968152 122962668

MCAZ:

138019738

MFOO:

137972648

PDAM:

113667031 113667535 113667537 113667543 113682193

SPIS:

111329435 111331008 111331012 111341739

DGT:

XEN:

RES:

Reference

PMID:25792749

Authors

Orlandi C, Xie K, Masuho I, Fajardo-Serrano A, Lujan R, Martemyanov KA

Title

Orphan Receptor GPR158 Is an Allosteric Modulator of RGS7 Catalytic Activity with an Essential Role in Dictating Its Expression and Localization in the Brain.

Journal

J Biol Chem 290:13622-39 (2015)
DOI:10.1074/jbc.M115.645374

Sequence

[mmu:241263]

LinkDB

DBGET integrated database retrieval system