KEGG ORTHOLOGY: K08788

ORTHOLOGY: K08788

Entry

K08788                      KO

Symbol

DMPK

Name

dystrophia myotonica-protein kinase [EC:2.7.11.1]

Disease

H00568

Myotonic dystrophy

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K08788  DMPK; dystrophia myotonica-protein kinase
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K08788  DMPK; dystrophia myotonica-protein kinase
Protein kinases [BR:ko01001]
Serine/threonine kinases: AGC group
  DMPK family [OT]
   K08788  DMPK; dystrophia myotonica-protein kinase

Genes

HSA:	1760(DMPK)

PTR:	456139(DMPK)

PPS:	100990838(DMPK)

GGO:	129528574(DMPK)

PON:	100434494(DMPK)

PPYG:

129021147(DMPK)

NLE:	100607645(DMPK)

HMH:	116483965(DMPK)

SSYN:

129466236(DMPK)

MCC:	715328(DMPK)

MCF:	102125829(DMPK)

MTHB:

126943431

MNI:	105478557(DMPK)

CSAB:

103234879(DMPK)

CATY:

105595163(DMPK)

PANU:

101003495(DMPK)

TGE:	112612350(DMPK)

MLEU:

105535869

RRO:	104673428(DMPK)

RBB:	108531039(DMPK)

TFN:	117091418(DMPK)

PTEH:

111519969(DMPK)

CANG:

105526873(DMPK)

CJC:	100412123(DMPK)

SBQ:	101027933(DMPK)

CIMI:

108285366(DMPK)

ANAN:

105713126(DMPK)

CSYR:

103269838(DMPK)

MMUR:

105869548(DMPK)

LCAT:

123623941(DMPK)

ERUF:

138375041(DMPK)

PCOQ:

105817674(DMPK)

OGA:	100963465(DMPK)

MMU:	13400(Dmpk)

MCAL:

110298912(Dmpk)

MPAH:

110336570(Dmpk)

RNO:	308405(Dmpk)

MCOC:

116101737(Dmpk)

ANU:	117698643(Dmpk)

ASYL:

127675799(Dmpk)

MUN:	110551517(Dmpk)

CGE:

113837295

MAUA:

101832685(Dmpk)

PROB:

127238438(Dmpk)

PLEU:

114682310(Dmpk)

PMAV:

102915010(Dmpk)

MORG:

121449604(Dmpk)

MFOT:

126490941

AAMP:

119820540(Dmpk)

CNL:	130867442(Dmpk)

NGI:	103749206(Dmpk)

HGL:	101702744(Dmpk)

CPOC:

100713533(Dmpk)

CCAN:

109692384(Dmpk)

DORD:

105998130(Dmpk)

DSP:	122125861(Dmpk)

DMER:

138812901 138814077

PLOP:

125368262(Dmpk)

NCAR:

124967560

MMMA:

107151341(Dmpk)

ITI:	101976212(Dmpk)

OCU:

127489120

OCZ:	121153824 121166906(DMPK)

TUP:	102487481(DMPK)

GVR:	103595243(DMPK)

CFA:	484436(DMPK)

CLUD:

112645284(DMPK)

VVP:	112931246(DMPK)

VLG:	121485649(DMPK)

NPO:	129500516(DMPK)

AML:	100474587(DMPK)

UMR:	103657059(DMPK)

UAH:	113243415(DMPK)

UAR:	123778732(DMPK)

ELK:

111160839

LLV:

125088796

MPUF:

101683618(DMPK)

MNP:	132005644(DMPK)

MLK:	131818629(DMPK)

NVS:	122911929(DMPK)

ORO:	101375567(DMPK)

EJU:	114197137(DMPK)

ZCA:	113936232(DMPK)

MLX:	117998155(DMPK)

NSU:	110572692(DMPK)

LWW:

102737362

FCA:	101081940(DMPK)

PYU:	121018633(DMPK)

PCOO:

112850735(DMPK)

PBG:	122494921(DMPK)

PVIV:

125153020(DMPK)

LRUF:

124511786

LGF:	123578178(DMPK)

AJU:

106973587

PTG:	102962404(DMPK)

PPAD:

109253214(DMPK)

PUC:

125915358

PLEZ:

122207979(DMPK)

HHV:	120241513(DMPK)

BTA:	513675(DMPK)

BOM:	102286002(DMPK)

BIU:	109572462(DMPK)

BBUB:

102414043(DMPK)

BKE:	129630905(DMPK)

BBIS:

104997710(DMPK)

CHX:	102173496(DMPK)

BTAX:

128064152(DMPK)

CSUM:

138097096(DMPK)

ODA:	120872271(DMPK)

CCAD:

122420152(DMPK)

MREE:

136161468(DMPK)

OVR:	110139923(DMPK)

MBEZ:

129546654(DMPK)

SSC:	100627008(DMPK)

CFR:	102509237(DMPK)

CBAI:

105062530(DMPK)

CDK:	105095439(DMPK)

VPC:	102536261(DMPK)

BACU:

103017207(DMPK)

BMUS:

118885030(DMPK)

LVE:	103071478(DMPK)

OOR:	101283334(DMPK)

LALB:

132509936(DMPK)

GMF:	115862278(DMPK)

DDP:	132416709(DMPK)

DLE:	111180724(DMPK)

PCAD:

102985208(DMPK)

PSIU:

116743960(DMPK)

PPHC:

136140174(DMPK)

NASI:

112415569(DMPK)

ECB:	100146609(DMPK)

EPZ:	103540673(DMPK)

EAI:	106843767(DMPK)

MYB:	102244114(DMPK)

MYD:	102770389(DMPK)

MMYO:

118652775(DMPK)

MLF:	102417573(DMPK)

MDT:	132216716(DMPK)

MYUM:

138999935(DMPK)

PKL:	118706817(DMPK)

EFUS:

103301376(DMPK)

MNA:	107536755(DMPK)

DRO:	112312913(DMPK)

SHON:

118995722(DMPK)

AJM:	119042973(DMPK)

PDIC:

114511311(DMPK)

PHAS:

123822950(DMPK)

MMF:	118639200(DMPK)

PPAM:

129082869(DMPK)

HAI:	109374726(DMPK)

RFQ:	117034556(DMPK)

PALE:

102894316(DMPK)

PGIG:

120605313(DMPK)

PVP:	105297332(DMPK)

RAY:	107515995(DMPK)

MJV:	108392089(DMPK)

TOD:	119248662(DMPK)

SARA:

101539062(DMPK)

SFUM:

130044436(DMPK)

SETR:

126028205(DMPK)

LAV:	100654571(DMPK)

TMU:

101357816

ETF:	101651800(DMPK)

DNM:	101439054(DMPK)

MDO:	100617691(DMPK)

GAS:	123239973(DMPK)

SHR:	100928713(DMPK)

AFZ:

127556295

PCW:	110203334(DMPK)

TVP:	118839657(DMPK)

PBRV:

138161413(DMPK)

MLAO:

141509595(DMPK)

OAA:	100084843 114812078

TACU:

119945912(DMPK)

ACOE:

138100602 138100603

ZLE:	135441372(DMPK)

TALA:

116965947(DMPK)

ACHC:

115338106(DMPK)

AGEN:

126035555 126036371

BBUT:

142026881(DMPK)

PARX:

142048975(DMPK)

CBOY:

140645373(DMPK)

MAME:

142403712(DMPK)

CNIC:

136001162(DMPK)

CRID:

134507704(DMPK)

AMJ:

102575607

CIZ:	142024462(DMPK)

CMY:	102945007(DMPK)

CCAY:

125628016(DMPK)

LKP:	140901922(DMPK)

NDS:	141976508(DMPK)

DCC:	119847155(DMPK)

CPIC:

101941971(DMPK)

MRV:	120388922(DMPK)

ACS:	100564621(dmpk)

ASAO:

132781986(DMPK)

PVT:	110075776(DMPK)

SUND:

121915139(DMPK)

PBI:	103063905(DMPK)

PMUR:

107291948(DMPK)

CTIG:

120299820(DMPK)

TSR:	106555534(DMPK)

PGUT:

117677745(DMPK)

PCAE:

139321496(DMPK)

APRI:

131204302(DMPK)

PTEX:

113453348(DMPK)

NSS:	113430233(DMPK)

VKO:	123026128(DMPK)

PMUA:

114603258(DMPK)

PRAF:

128420250(DMPK)

ZVI:	118085951(DMPK)

HCG:	128333274(DMPK)

GJA:	107109790(DMPK)

STOW:

125435548(DMPK)

EMC:	129343329(DMPK)

XLA:	108698524(dmpk.L) 108700203(dmpk.S)

XTR:	100491375(dmpk)

NPR:	108791125(DMPK)

RTEM:

120913557(DMPK)

ACAT:

141107944(DMPK)

PADS:

140342977(DMPK)

BBUF:

121009358(DMPK)

BGAR:

122946036(DMPK)

DTC:	141052128(DMPK)

PWL:	138259836(DMPK)

DRE:	101886625(dmpK)

SRX:	107710396 107741373

SANH:

107671610 107690849

SGH:	107565533 107575144 107575145

CCAR:

CAUA:

CGIB:

PTET:

LROH:

GRF:	141299130 141299622

OMC:

MAMB:

CIDE:

CERY:

MASI:

TROS:

TDW:

MANU:

PDAB:

IPU:

IFU:

PHYP:

113543441(dmpk)

SMEO:

TFD:

TVC:

CGAR:

NGRA:

TRN:

AMEX:

CMAO:

EEE:	113581191(dmpk)

CHAR:

SPIL:

ASAD:

TRU:

TFS:

LCO:	104937701(dmpk)

TBEN:

117472180

CGOB:

115019418(dmpk)

PGEO:

GACU:

EMAC:

ELY:

EFO:

PLEP:

SLUC:

ECRA:

ESP:	116686858(dmpk)

PFLV:

114566703(dmpk)

CVE:

MSAM:

SCHU:

EARM:

CUD:

SPUL:

LMIX:

HTC:	141791259(dmpk)

ASTR:

137606554

PKLU:

139212947

MZE:	101472332(dmpk)

ONL:	100699177(dmpk)

OAU:

OLA:

OML:

CSAI:

EJA:

BFRE:

CSEM:

103395032(dmpk)

POV:

SSEN:

SSOE:

HHIP:

HSP:

PPLT:

LCF:

SDU:	111234565(dmpk)

SLAL:

111654001(dmpk)

XGL:

120802153

BPEC:

110159485

ENY:

140361193

MALB:

109972713(dmpk)

SJO:

SSCO:

TTY:

GMH:

SASA:

STRU:

OTW:	112228332 112258078

OMY:	110533420 110537712

OGO:	124000459 124013404

ONE:	115105300 115136128

OKI:	109873394 109892938

OKE:	118389848 118391758

OMM:	135548854 135550930

OCLA:

139418056 139420770

SALP:

111950110 111979959

SNH:	120043894 120056780

SFON:

129820306 129868167

CCLU:

121573990 121579248

ELS:	105011017(dmpk)

OEP:

134013889

SFM:	108921521 108927233

PKI:	111850657(dmpk) 111861144

AANG:

118210427 118234948

AROT:

135236080 135263528

CCOG:

133108680 133133173

LOC:	102691465(dmpk)

PSPA:

121303900 121304886

ARUT:

117397352 117415067

PSEX:

120538716

LCM:	102357534(DMPK)

» show all

Reference

PMID:7905855

Authors

Shaw DJ, McCurrach M, Rundle SA, Harley HG, Crow SR, Sohn R, Thirion JP, Hamshere MG, Buckler AJ, Harper PS, et al.

Title

Genomic organization and transcriptional units at the myotonic dystrophy locus.

Journal

Genomics 18:673-9 (1993)
DOI:10.1016/s0888-7543(05)80372-6

Sequence

[hsa:1760]

Reference

PMID:10913253

Authors

Bush EW, Helmke SM, Birnbaum RA, Perryman MB

Title

Myotonic dystrophy protein kinase domains mediate localization, oligomerization, novel catalytic activity, and autoinhibition.

Journal

Biochemistry 39:8480-90 (2000)
DOI:10.1021/bi992142f

Sequence

[hsa:1760]

LinkDB

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