KEGG ORTHOLOGY: K08799

ORTHOLOGY: K08799

Entry

K08799                      KO

Symbol

MELK

Name

maternal embryonic leucine zipper kinase [EC:2.7.11.1]

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K08799  MELK; maternal embryonic leucine zipper kinase
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K08799  MELK; maternal embryonic leucine zipper kinase
Protein kinases [BR:ko01001]
Serine/threonine kinases: CAMK group
  CAMKL family
   K08799  MELK; maternal embryonic leucine zipper kinase

Genes

HSA:	9833(MELK)

PTR:	465095(MELK)

PPS:	100970650(MELK)

GGO:	101129924(MELK)

PON:	100459042(MELK)

PPYG:

129044258(MELK)

NLE:	100586707(MELK)

HMH:	116475090(MELK)

SSYN:

129490160(MELK)

MCC:	716875(MELK)

MCF:	101867391(MELK)

MTHB:

126938039

MNI:	105485788(MELK)

CSAB:

103219188(MELK)

CATY:

105598153(MELK)

PANU:

101008096(MELK)

TGE:	112608569(MELK)

MLEU:

105554219(MELK)

RRO:	104667509(MELK)

RBB:	108542573(MELK)

TFN:	117098984(MELK)

PTEH:

111536743(MELK)

CANG:

105509914(MELK)

CJC:	100386947(MELK)

SBQ:	101039982(MELK)

CIMI:

108314276(MELK)

ANAN:

105724621(MELK)

CSYR:

103276731(MELK)

MMUR:

105874281(MELK)

LCAT:

123645892(MELK)

ERUF:

138387407(MELK)

PCOQ:

105819739(MELK)

OGA:	100962846(MELK)

MMU:	17279(Melk)

MCAL:

110292563(Melk)

MPAH:

110338660(Melk)

RNO:	362510(Melk)

MCOC:

116095926(Melk)

ANU:	117708587(Melk)

ASYL:

127680738(Melk)

MUN:	110553820(Melk)

CGE:	100774970(Melk)

MAUA:

101824893(Melk)

PROB:

127224614(Melk)

PLEU:

114710588(Melk)

PMAV:

102925813(Melk)

MORG:

121458366(Melk)

MFOT:

126509897

AAMP:

119826438(Melk)

CNL:	130887921(Melk)

NGI:	103745726(Melk)

HGL:	101699732(Melk)

CPOC:

100735931(Melk)

CCAN:

109688068(Melk)

DORD:

105993348(Melk)

DSP:	122122174(Melk)

DMER:

138818801(Melk)

PLOP:

125342198(Melk)

NCAR:

124964877

MMMA:

107147791(Melk)

ITI:	101961537(Melk)

OCU:

100349805

OPI:	101527875(MELK)

OCZ:	121172434(MELK)

TUP:	102480631(MELK)

GVR:	103603882(MELK)

CFA:	481608(MELK)

CLUD:

112650022(MELK)

VVP:	112930812(MELK)

VLG:	121495399(MELK)

NPO:	129495257(MELK)

AML:	100481417(MELK)

UMR:	103678474(MELK)

UAH:	113260450(MELK)

UAR:	123781303(MELK)

ELK:

111145797

LLV:

125083843

MPUF:

101693820(MELK)

MNP:	132025086(MELK)

MLK:	131812786(MELK)

NVS:	122917461(MELK)

ORO:	101367102(MELK)

EJU:	114213509(MELK)

ZCA:	113934521(MELK)

MLX:	118017945(MELK)

NSU:	110581499(MELK)

LWW:	102738946(MELK)

FCA:	101099597(MELK)

PYU:	121034675(MELK)

PCOO:

112853450(MELK)

PBG:	122474629(MELK)

PVIV:

125150659(MELK)

LRUF:

124501889

LGF:	123593357(MELK)

AJU:

106981304

PTG:	102960940(MELK)

PPAD:

109270139(MELK)

PUC:

125919675

PLEZ:

122205408(MELK)

HHV:	120233534(MELK)

BTA:	520088(MELK)

BOM:	102284750(MELK)

BIU:	109563038(MELK)

BBUB:

102392549(MELK)

BKE:	129650259(MELK)

BBIS:

104992984(MELK)

CHX:	102186868(MELK)

OAS:	101108986(MELK)

BTAX:

128052533(MELK)

CSUM:

138081041(MELK)

ODA:	120883479(MELK)

CCAD:

122453195(MELK)

MREE:

136148442(MELK)

OVR:	110127843(MELK)

MBEZ:

129557334(MELK)

SSC:	100519998(MELK)

CFR:	102518207(MELK)

CBAI:

105067354(MELK)

CDK:	105102269(MELK)

VPC:	102536082(MELK)

BACU:

103008530(MELK)

BMUS:

118896978(MELK)

LVE:	103069274(MELK)

OOR:	101278079(MELK)

LALB:

132522847(MELK)

GMF:	115867853(MELK)

DDP:	132426594(MELK)

DLE:	111187983(MELK)

PCAD:

102990530(MELK)

PSIU:

116756093(MELK)

PPHC:

136124071(MELK)

NASI:

112411734(MELK)

ECB:	100055291(MELK)

EPZ:	103540500(MELK)

EAI:	106827615(MELK)

MYB:	102257383(MELK)

MYD:	102768607(MELK)

MMYO:

118667313(MELK) 118675305

MLF:	102417656(MELK)

MDT:	132212150(MELK)

MYUM:

139020474(MELK)

PKL:	118716326(MELK)

EFUS:

103286592(MELK) 129151166

MNA:	107544987(MELK)

DRO:	112304525(MELK)

SHON:

118979791(MELK)

AJM:	119048760(MELK)

PDIC:

114496957(MELK)

PHAS:

123819938(MELK)

MMF:	118629736(MELK)

PPAM:

129079689(MELK)

HAI:	109393743(MELK)

RFQ:	117032047(MELK)

PALE:

102888983(MELK)

PGIG:

120597926(MELK)

PVP:	105296222(MELK)

RAY:	107502840(MELK)

MJV:	108398243(MELK)

TOD:	119231097(MELK)

SARA:

101555232(MELK)

SFUM:

130026473(MELK)

SETR:

126006960(MELK)

LAV:	100654298(MELK)

TMU:

101345268

ETF:	101660172(MELK)

DNM:	101414366(MELK)

MDO:	100018004(MELK)

GAS:	123231274(MELK)

SHR:	100927662(MELK)

AFZ:

127561070

PCW:	110220576(MELK)

TVP:	118829291(MELK)

PBRV:

138158914(MELK)

MLAO:

141497676(MELK)

OAA:	100078125(MELK)

TACU:

119948037(MELK)

GGA:	428391(MELK)

PCOC:

116235183 116239458(MELK)

MGP:	100549393(MELK)

CJO:

107306916

TPAI:

128074148(MELK)

LMUT:

125700559(MELK)

NMEL:

110390084(MELK)

APLA:

113840953 119714521

AACU:

137848607(MELK)

ACYG:

106048836(MELK)

CATA:

118258676(MELK)

AFUL:

116500766(MELK)

TGU:	100219328(MELK)

LSR:	110482526(MELK)

SCAN:

103823059(MELK)

PMOA:

120501769(MELK)

OTC:	121335962(MELK)

PRUF:

121351299(MELK)

ATRC:

139604114(MELK)

GFR:	102038867(MELK)

FAB:	101814574(MELK)

OMA:	130264664(MELK)

PHI:	102099776(MELK)

PMAJ:

107198389(MELK)

CCAE:

111941622(MELK)

CCW:	104695818(MELK)

CBRC:

103617109(MELK)

ACOE:

138103241(MELK)

ETL:	114055215(MELK)

ZAB:	102072686(MELK)

ZLE:	135459512(MELK)

SVG:	106861542(MELK)

MMEA:

130587116(MELK)

HRT:	120765383(MELK)

SATI:

136374109(MELK)

CCIC:

134056498(MELK)

FPG:	101923751(MELK)

FCH:	102045820(MELK)

NNT:	104406411(MELK)

SHAB:

115600735(MELK)

ACUN:

113490418(MELK)

SURA:

141937733(MELK)

TALA:

104365317(MELK)

ACHC:

115337336(MELK)

HALD:

104323919(MELK)

HLE:	104831084(MELK)

AGEN:

126036319

BBUT:

142026424(MELK)

GCL:

127027392

CSTI:

104556833(MELK)

LDI:	104339690(MELK)

DPUB:

104306272(MELK)

PPUS:

135193111(MELK)

AVIT:

104267250(MELK)

BRHI:

104489289(MELK)

EGZ:	104129509(MELK)

NNI:	104010544(MELK)

PCRI:

104031346(MELK)

PCAO:

104049559(MELK)

PARX:

142049989(MELK)

PADL:

103914600(MELK)

AFOR:

103900059(MELK)

CBOR:

142075276(MELK)

GSTE:

104255528(MELK)

CBOY:

140651396(MELK) 140651397 140651479

MAME:

142402818 142402820 142402822 142402824 142402843(MELK)

CLV:	102097717(MELK)

CNIC:

136002203(MELK)

MUI:	104546302(MELK)

PGUU:

104463684(MELK)

PLET:

104616215(MELK)

EHS:

104510263

CMAC:

104480625(MELK)

CUCA:

104061100(MELK)

TEO:	104375658(MELK)

BREG:

104639079(MELK)

GAME:

129199321(MELK)

OHA:	104331736(MELK)

ACAR:

104527161

CPEA:

104394097(MELK)

CVF:	104291127(MELK)

RTD:	128902928(MELK)

CRID:

134508822(MELK)

LMIC:

141736402(MELK)

AAM:	106487478(MELK)

AROW:

112969711(MELK)

NPD:	112946283(MELK)

TGT:	104573456(MELK)

DNE:	112982756(MELK)

SCAM:

104145792(MELK)

ASN:	102388593(MELK)

AMJ:	102570510(MELK)

PSS:	102448331(MELK)

CIZ:	142012980(MELK)

CMY:	102935928(MELK)

CCAY:

125636609(MELK)

LKP:	140911831(MELK)

NDS:	141987105(MELK)

DCC:	119855749(MELK)

CPIC:

101936688

TST:	117879543(MELK)

CABI:

116823857(MELK)

MRV:	120408410(MELK)

ACS:	100555349(melk)

ASAO:

132768115(MELK)

PVT:	110077854(MELK)

SUND:

121924357(MELK)

PBI:	103050203(MELK)

PMUR:

107294048(MELK)

CTIG:

120308573(MELK)

TSR:	106537475(MELK)

PGUT:

117661680(MELK)

PCAE:

139311097(MELK)

APRI:

131193266(MELK)

PTEX:

113444108(MELK)

NSS:	113415438(MELK)

VKO:	123028077(MELK)

PMUA:

114587578(MELK)

PRAF:

128404649(MELK)

ZVI:	118097791(MELK)

HCG:	128347036(MELK)

GJA:	107122991(MELK)

STOW:

125437255(MELK)

EMC:	129334535(MELK)

XLA:	397927(melk.L)

XTR:	549144(melk)

NPR:	108783778(MELK)

RTEM:

120946864(MELK)

ACAT:

141102764(MELK)

PADS:

140326176(MELK)

BBUF:

120991570(MELK)

BGAR:

122920961 122931725

DTC:	141052427(MELK)

PWL:	138299383(MELK)

MUO:	115480738(MELK)

GSH:	117365866(MELK)

DRE:	30724(melK)

SRX:	107709443 107750464

SANH:

107702285

SGH:	107548315(melk) 107570222

CCAR:

109093017 109095665

CAUA:

113044244(melk) 113107086

CGIB:

127948449 127958847

PTET:

122348326(melk)

LROH:

127168421(melk)

GRF:	141337152(melk)

OMC:	131553334(melk)

PPRM:

120493982(melk)

RKG:	130089551(melk)

MAMB:

125272634(melk)

CIDE:

127524666

CERY:

137032280(melk)

MASI:

127443633 127445497

TROS:

130553300(melk)

TDW:	130408093(melk)

MANU:

129444691(melk)

PDAB:

135760946(melk)

IPU:

108260808

IFU:	128604213(melk)

PHYP:

113547318(melk)

SMEO:

124381697(melk)

TFD:	113635405(melk)

TVC:	132841954(melk)

CGAR:

128508610(melk)

NGRA:

132883275(melk)

AMEX:

111195193(melk)

CMAO:

118816861(melk)

EEE:	113588276(melk)

CHAR:

105903579(melk)

SPIL:

134059799(melk)

ASAD:

121713186(melk)

TRU:	101072886(melk)

TFS:	130527799(melk)

TNG:	GSTEN00033060G001

LCO:	104935965(melk)

NCC:	104951399(melk)

TBEN:

117474828(melk)

CGOB:

115009538(melk)

PGEO:

117445347(melk)

GACU:

117543356(melk)

EMAC:

134864037(melk)

ELY:	117254932(melk)

EFO:	125886453(melk)

PLEP:

121942219(melk)

SLUC:

116040556(melk)

ECRA:

117935866(melk)

ESP:	116706065(melk)

PFLV:

114568419(melk)

GAT:	120825602(melk)

PPUG:

119217808(melk)

AFB:	129095834(melk)

CLUM:

117736450(melk)

PSWI:

130190209(melk)

CANA:

137794866(melk)

CVE:	137884912(melk)

MSAM:

119899091(melk)

SCHU:

122873274(melk)

EARM:

139295358(melk)

CUD:	121507912(melk)

SPUL:

138594878(melk)

LMIX:

132995021(melk)

HTC:	141801601(melk)

ALAT:

119028943(melk)

ASTR:

137600463(melk)

PKLU:

139198594(melk)

MZE:	101471713(melk)

ONL:	100689948(melk)

OAU:	116311139(melk)

OLA:	101169663(melk)

OML:	112157489(melk)

CSAI:

133451209(melk)

XMA:	102222109(melk)

XCO:	114144201(melk)

XHE:	116719543(melk)

PRET:

103466648(melk)

PFOR:

103130670(melk)

PLAI:

106958652(melk)

PMEI:

106906461(melk)

GAF:	122830196(melk)

CVG:	107085696(melk)

CTUL:

119794220(melk)

GMU:	124867872(melk)

NFU:	107382151(melk)

KMR:	108236547(melk)

ALIM:

106520933(melk)

NWH:	119408124(melk)

AOCE:

111567855(melk)

EJA:	138209056(melk)

BFRE:

138620166(melk)

MCEP:

125000264(melK)

CSEM:

103383713(melk)

POV:	109637713(melk)

SSEN:

122770495(melk)

SSOE:

131467550(melk)

HHIP:

117767688(melk)

HSP:	118100571(melk)

PPLT:

128436726(melk)

SMAU:

118313014(melk)

LCF:

108896587

SDU:	111231438(melk)

SLAL:

111663994(melk)

XGL:	120799904(melk)

HCQ:	109519943(melk)

SSCV:

125968558(melk)

SBIA:

133506636(melk)

PEE:	133404047(melk)

PTAO:

133477031(melk)

BPEC:

110165297(melk)

ENY:	140378076(melk)

MALB:

109974164(melk)

BSPL:

114853892(melk)

SJO:	128371676(melk)

SSCO:

133990946(melk)

TTY:	137179704(melk)

GMH:	115540747(melk)

SASA:

106594008 106610569(melk)

STRU:

115186312(melk)

OTW:	112242332 121843616

OMY:	110514239 110514629

OGO:	124022341 124022753 124022868

OKI:	109886836 109886837

OKE:	127919712(melk)

OMM:	135530812 135533000

OCLA:

139394396 139394646

SNH:	120037938(melk)

SFON:

129856019(melk)

CCLU:

121579279(melk)

ELS:	105007030(melk)

OEP:	134033616(melk)

SFM:	108925922(melk)

PKI:	111844202(melk)

AANG:

118227058(melk)

AROT:

135254397(melk)

CCOG:

133130853(melk)

LOC:	102694285(melk)

PSPA:

121319372(melk)

ARUT:

117421510(melk)

PSEX:

120532365(melk)

LCM:	102352620(MELK) 102352831

CMK:	103182150(melk)

RTP:	109912910(melk)

CPLA:

122564512(melk)

CPUN:

140491481(melk)

HOC:	132829224(melk)

SCAU:

119970248(melk)

LERI:

129695614(melk)

HAKA:

140713626(melk)

PMRN:

116951067(MELK)

LRJ:	133354409 133354412

BFO:

BBEL:

CIN:

SCLV:

CLEP:

SPU:

LPIC:

129281358 129281581 129282235

LVG:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:

PFLL:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

ACOC:

MZT:

CCOA:

TCZ:

TSEP:

PBAR:

VEM:

COBS:

TLN:

TAME:

HST:

DQU:

CFO:

FEX:

PMEC:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:	100123808(Melk)

MDL:

CGLO:

CTYP:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

TMOL:

DPA:

ESIM:

EFOR:

SOY:

RFG:

AGRG:

ATD:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

LDA:

HVI:

MQU:

PHU:	Phum_PHUM101530

FOC:

TPAL:

ZNE:

CSEC:

PAME:

SGRE:

BROR:

IEL:

HAMR:

FCD:	110844107 110859074

DPX:	DAPPUDRAFT_304752

DMK:

DPZ:

AFRA:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

MRJ:

PORN:

HAZT:

OOT:

EAF:

LSM:

TCF:

PPOI:

DSV:	119438181 119445215

DALB:

RSAN:

RMP:

VDE:

VJA:

GOE:

TUT:

DPTE:

DFR:	124496028 124497153

CSCU:

CVS:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

CEL:	CELE_W03G1.6(pig-1)

CBR:	CBG_01615(Cbr-pig-1)

CRQ:	GCK72_014689

NAI:	NECAME_17225

BMY:	BM_BM6168(Bma-pig-1)

LOA:	LOAG_00732

TSP:

Tsp_03506

HRO:	HELRODRAFT_191046

LGI:	LOTGIDRAFT_170401

PVUL:

PCAN:

LSAX:

BARL:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

YBA:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

SMM:	Smp_166150

OVI:	T265_15136

EGL:

LLON:

NVE:

EPA:

ATEN:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:	100206440 101238218

HSY:	130654606 130655967

RES:	135685951 135686429

TAD:	TRIADDRAFT_50686

AQU:

100640175

CCLM:

134180978

MBR:	MONBRDRAFT_29648 MONBRDRAFT_32778

SRE:	PTSG_01778 PTSG_05194

» show all

Reference

PMID:16216881

Authors

Beullens M, Vancauwenbergh S, Morrice N, Derua R, Ceulemans H, Waelkens E, Bollen M

Title

Substrate specificity and activity regulation of protein kinase MELK.

Journal

J Biol Chem 280:40003-11 (2005)
DOI:10.1074/jbc.M507274200

Sequence

[hsa:9833]

LinkDB

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