KEGG   ORTHOLOGY: K09459
Entry
K09459                      KO                                     
Symbol
E4.1.1.82
Name
phosphonopyruvate decarboxylase [EC:4.1.1.82]
Pathway
map00440  Phosphonate and phosphinate metabolism
map00998  Biosynthesis of various antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
Module
M00903  Fosfomycin biosynthesis, phosphoenolpyruvate => fosfomycin
Reaction
R04053  3-phosphonopyruvate carboxy-lyase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00440 Phosphonate and phosphinate metabolism
    K09459  E4.1.1.82; phosphonopyruvate decarboxylase
  09110 Biosynthesis of other secondary metabolites
   00998 Biosynthesis of various antibiotics
    K09459  E4.1.1.82; phosphonopyruvate decarboxylase
Enzymes [BR:ko01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.82  phosphonopyruvate decarboxylase
     K09459  E4.1.1.82; phosphonopyruvate decarboxylase
Other DBs
GO: 0033980
Genes
ZNE: 110841498
CSEC: 111875044
SGRE: 126298672
BROR: 134540720
FCD: 110847575
PPOI: 119111117 119111763
LGI: LOTGIDRAFT_114966
PVUL: 126824792
PCAN: 112559357
HRJ: 124268737
HASI: 137261656
OED: 125646416
MYI: 110448928
PMAX: 117336379
MCAF: 127705869
MMER: 123537598
RPHI: 132722180
MAEA: 128231744
OBI: 106874397
LJP: 135468502
NVE: 5511287
EPA: 110243717
ATEN: 116287539
ADF: 107333309
AMIL: 114948801
PDAM: 113684314
SPIS: 111344557
DGT: 114523267
XEN: 124452918
HMG: 100197891
HSY: 130629280
RES: 135680883
TCR: 505965.50
HDE: HDEF_0202
BSEL: RHD99_08495(aepY)
SRL: SOD_c30100(bcpC)
FSM: CCS41_00900(aepY)
PROD: PCO85_08035(aepY)
ECA: ECA0488(fom2)
PATR: EV46_02525
PATO: GZ59_05040(fom2)
PCT: PC1_0477
PEC: W5S_0591
PPUJ: E2566_02930(aepY)
PARI: I2D83_19360(aepY)
PCAC: OI450_03790(aepY)
PCOA: PJ912_15830(aepY)
PPEU: DUT67_19405(aepY)
LBQ: CKQ53_06555(aepY)
LPOP: I6N93_15655(aepY)
EPE: CI789_05495(aepY)
PLF: PANA5342_2584(ppd)
PAJ: PAJ_2521
XVA: C7V42_03525(aepY)
XHY: FZ025_12105(aepY)
XDY: NYR95_03915(aepY)
PTRE: I9H09_23710(aepY)
SDN: Sden_1162
NOC: Noc_1316
NHL: Nhal_1305
NWA: Nwat_1198
NWR: E3U44_16830(aepY)
NTT: TAO_1302
NTG: NSCAC_0557(ppd)
MPRF: J8N69_05405(aepY)
SALN: SALB1_2155
RME: Rmet_1809(ppd)
CPAU: EHF44_14445(aepY)
COX: E0W60_18820(aepY)
CCAM: M5D45_07520(aepY)
CUPE: KLP38_07745(aepY)
BMA: BMAA1769(ppd)
BMV: BMASAVP1_0759(ppd)
BMAL: DM55_4013(aepY)
BMAQ: DM76_4709(aepY)
BMAI: DM57_07160
BMAF: DM51_3462(aepY)
BMAZ: BM44_3973(aepY)
BMAB: BM45_4750(aepY)
BPD: BURPS668_A0779(aepY_2) BURPS668_A0909(aepY_1)
BPSE: BDL_3734(aepY) BDL_3836(aepY)
BPSM: BBQ_5586(aepY) BBQ_5688(aepY)
BPSU: BBN_3908(aepY) BBN_4008(aepY)
BPSD: BBX_5571(aepY) BBX_5673(aepY)
BPK: BBK_3882(aepY) BBK_5713(aepY)
BPSH: DR55_4743(aepY) DR55_4844(aepY)
BPSA: BBU_5437(aepY) BBU_5539(aepY)
BPSO: X996_3789(aepY) X996_4594(aepY)
BUT: X994_4010(aepY) X994_4112(aepY)
BTQ: BTQ_5191(aepY)
BTJ: BTJ_3821(aepY)
BTZ: BTL_4577(aepY) BTL_4677(aepY)
BTD: BTI_5337(aepY)
BTV: BTHA_5552(aepY)
BTHE: BTN_4316(aepY)
BTHM: BTRA_4581(aepY)
BTHL: BG87_4648(aepY)
BOK: DM82_4610(aepY) DM82_4704(aepY)
BOC: BG90_5889(aepY) BG90_5981(aepY)
BHG: I6G56_25500(aepY)
BVE: AK36_4233(aepY)
BCJ: BCAM1244
BCEN: DM39_3754(aepY)
BCEW: DM40_4162(aepY)
BCEO: I35_5093
BAM: Bamb_3534
BMJ: BMULJ_04038(ppd)
BMU: Bmul_4472
BMK: DM80_3633(aepY)
BMUL: NP80_4147(aepY)
BCT: GEM_4496
BCED: DM42_3847(aepY)
BDL: AK34_4231(aepY)
BCON: NL30_06375
BUB: BW23_4918(aepY)
BLAT: WK25_23145
BTEI: WS51_03915
BSEM: WJ12_26080
BPSL: WS57_07795
BMEC: WJ16_24705
BSTG: WT74_25010
BANN: JFN94_23425(aepY)
BARI: NLX30_32415(aepY)
BAEN: L3V59_19230(aepY)
BSER: R0290_25565(aepY)
BGU: KS03_4594(aepY)
BGO: BM43_5002(aepY)
BUK: MYA_4543
BUL: BW21_5017(aepY)
BURK: DM992_19620(aepY)
BXE: Bxe_B2234
BXB: DR64_4565(aepY)
BPH: Bphy_3821
BFN: OI25_4535(aepY)
PSPW: BJG93_18655(aepY)
PARB: CJU94_32425(aepY)
PHS: C2L64_30755(aepY)
PTER: C2L65_27415(aepY)
PGP: CUJ91_19560(aepY)
PCJ: CUJ87_30245(aepY)
PTS: CUJ90_26945(aepY)
PMEG: FNZ07_08535(aepY)
PTRO: G5S35_19395(aepY)
PGIS: I6I06_19280(aepY)
PACP: FAZ97_15195(aepY)
PACS: FAZ98_20210(aepY)
PEW: KZJ38_30040(aepY)
PDIO: PDMSB3_0866.1(ppd)
PBRY: NDK50_32645(aepY)
PSAA: QEN71_14450(aepY)
PKF: RW095_11995(aepY)
PBON: QS306_15250(aepY)
PPAI: E1956_23910(aepY)
PPNO: DA70_09040
PPNM: LV28_21765
PPUL: RO07_16155
PSPU: NA29_20995
PAPI: SG18_00145
PAND: DRB87_06675(aepY)
PFIB: PI93_020430(aepY)
PCOM: NTU39_08425(aepY)
PANX: OYT13_06675(aepY)
CABA: SBC2_10690
CABK: NK8_07540(aepY)
TCAR: U0034_22535(aepY)
AAA: Acav_2123
MMEC: FIU01_07275(aepY)
AZO: azo2699
AOA: dqs_2834
AVI: Avi_3414
ARA: Arad_7868
AOL: S58_09490
BROS: QUH67_10085(aepY)
SIW: GH266_09710(aepY)
ROS: CTJ15_07645(aepY)
RMUC: FOB66_09670(aepY)
RMT: IAI58_18635(aepY)
LCK: HN018_01550(aepY)
AZZ: DEW08_28015(aepY)
ECOG: FIV45_08010(aepY)
SNEA: NBZ79_03290(aepY)
HWI: A0Z60_07475(aepY)
CJU: C8J_1330
CHYO: CHH_1592
CHW: A2J15_004810(aepY)
CINF: CINF_1347
DAL: Dalk_1322
DLI: dnl_05850
BSTO: C0V70_16035(aepY)
BMQ: BMQ_0785(aepY)
BMD: BMD_0786(aepY)
BMH: BMWSH_4463(ppd)
BMEG: BG04_3079(aepY)
PTB: DER53_11740(aepY)
MEKU: HUW50_16410(aepY)
BOU: I5818_22335(aepY)
BRW: GOP56_09090(aepY)
PPOL: X809_41425
PLUT: EI981_13660(aepY)
PCHI: PC41400_18310(aepY)
PTHI: NDS46_01340(aepY)
PKA: PQ456_19755(aepY)
PHEX: L0M14_27415(aepY)
PACL: DCC85_01110(aepY)
ANEU: PP175_10610(aepY) PP175_13690(aepY)
ADAU: NZD86_21655(aepY)
CTC: CTC_01699
CBE: Cbei_4337
CBZ: Cbs_4337
CBEI: LF65_04861
CSR: Cspa_c46180(bcpC)
CSB: CLSA_c08740(bcpC)
CDY: F3K33_22180(aepY)
CCAA: KQH81_02880(aepY)
CNN: CNEO_1088(ppd)
RCH: RUM_11410
ALAC: JYE50_04505(aepY) JYE50_12335(aepY)
AHC: JYE49_05000(aepY)
BPEN: NQ488_09085(aepY)
CBAF: JS518_04520(aepY) JS518_12265(aepY)
RRK: H8S51_002425(aepY)
BPRO: PMF13cell1_05127(mdlC)
HHJ: NQ487_01305(aepY)
TIZ: RBU61_14845(aepY)
SDIA: QU667_11315(aepY)
STIM: H1B31_02565(aepY)
OLS: Olsu_0592
NTP: CRH09_19450(aepY)
NOZ: DMB37_08000(aepY)
SCO: SCO6824(SC1A2.33c)
SALS: SLNWT_3224
SALW: CP975_03130(aepY)
SRJ: SRO_1309
SSEO: D0Z67_12190(aepY)
SRIM: CP984_37455(aepY)
SDW: K7C20_15035(aepY)
SGOB: test1122_07760(aepY)
SCIR: STRCI_003016(aepY)
SCAY: PYS65_02420(aepY)
SPRF: K4G22_27920(aepY)
CELH: GXP71_14040(aepY)
NAKE: KGD83_08790(aepY)
SAIU: J4H86_04285(aepY)
FAL: FRAAL6378
AMYY: YIM_29485
SSYI: EKG83_20795(aepY)
MPRN: Q3V37_07940(aepY)
ASIC: Q0Z83_111410(aepY)
AOU: ACTOB_005082(aepY)
NHY: JQS43_02330(aepY)
SNA: Snas_5664
NAV: JQS30_13660(aepY)
NED: HUN01_29210(aepY)
TOQ: HCG51_21870(aepY)
SCYT: SAMD_46610
LMAJ: GKN94_04165(aepY)
OTE: Oter_2977
ELUT: CKA38_13740(aepY)
TDE: TDE_1414
TPI: TREPR_2365(aepY)
TPHG: FUT81_06850(aepY)
TRI: DYE50_04585(aepY)
TPAV: HRQ91_06195(aepY)
TSK: HRI97_05660(aepY)
TAZ: TREAZ_2215(aepY)
BHC: JFL75_01535(aepY)
BIP: Bint_1238
FSC: FSU_1438
BTH: BT_1719
BTHO: Btheta7330_01296(ilvB)
BFS: BF9343_1815(aepY)
BSTE: K6V31_00390(aepY)
PARC: CI960_12855(aepY)
PCOI: LK433_14485(aepY)
DRC: G0Q07_19265(aepY)
FUV: JR347_10755(aepY)
RCG: N7E81_15225(aepY)
PROC: Ptc2401_00815(ilvB_1)
NDE: NIDE2902(ppd)
NVA: G3M78_03285(aepY)
PSYT: DSAG12_01621(aepY)
AG: BAA07055(bcpC) BAA32496(fom2)
 » show all
Reference
PMID:9127192
  Authors
Nakashita H, Watanabe K, Hara O, Hidaka T, Seto H
  Title
Studies on the biosynthesis of bialaphos. Biochemical mechanism of C-P bond formation: discovery of phosphonopyruvate decarboxylase which catalyzes the formation of phosphonoacetaldehyde from phosphonopyruvate.
  Journal
J Antibiot (Tokyo) 50:212-9 (1997)
DOI:10.7164/antibiotics.50.212
Reference
  Authors
Nakashita H, Kozuka K, Hidaka T, Hara O, Seto H
  Title
Identification and expression of the gene encoding phosphonopyruvate decarboxylase of Streptomyces hygroscopicus.
  Journal
Biochim Biophys Acta 1490:159-62 (2000)
DOI:10.1016/s0167-4781(99)00249-3
  Sequence
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