KEGG   ORTHOLOGY: K09472
Entry
K09472                      KO                                     
Symbol
puuC, aldH
Name
4-(gamma-glutamylamino)butanal dehydrogenase [EC:1.2.1.99]
Pathway
map00330  Arginine and proline metabolism
map01100  Metabolic pathways
Module
M00136  GABA biosynthesis, prokaryotes, putrescine => GABA
Reaction
R07417  4-(gamma-L-glutamylamino)butanal:NAD+ oxidoreductase
R07418  4-(gamma-L-glutamylamino)butanal:NADP+ oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00330 Arginine and proline metabolism
    K09472  puuC, aldH; 4-(gamma-glutamylamino)butanal dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.99  4-(gamma-glutamylamino)butanal dehydrogenase
     K09472  puuC, aldH; 4-(gamma-glutamylamino)butanal dehydrogenase
Other DBs
COG: COG1012
Genes
ECO: b1300(puuC)
ECJ: JW1293(puuC)
ECD: ECDH10B_1417(puuC)
EBW: BWG_1132(puuC)
ECOK: ECMDS42_1098(puuC)
ECOC: C3026_07630
ECE: Z2488(aldH)
ECS: ECs_1877(puuC)
ECF: ECH74115_1942(puuC)
ETW: ECSP_1825(puuC)
EOI: ECO111_1683(puuC)
EOJ: ECO26_1867(puuC)
EOH: ECO103_1464(puuC)
ECOO: ECRM13514_1727(aldH)
ECOH: ECRM13516_1691(aldH)
ESL: O3K_13830
ESO: O3O_11800
ESM: O3M_13805
ECK: EC55989_1462(puuC)
EOK: G2583_1647(puuC)
ELH: ETEC_1404
ECW: EcE24377A_1510(puuC)
EUN: UMNK88_1636(puuC)
ECX: EcHS_A1415(puuC)
ECM: EcSMS35_1822(puuC)
ECY: ECSE_1352
ECR: ECIAI1_1325(puuC)
EUM: ECUMN_1606(puuC)
ECT: ECIAI39_1651(puuC)
EBR: ECB_01277(aldH)
EBL: ECD_01277(puuC)
EBE: B21_01288(puuC)
EBD: ECBD_2317
ELO: EC042_1428(puuC)
EKF: KO11_16310(puuC)
EDJ: ECDH1ME8569_1242(puuC)
ELW: ECW_m1396(puuC)
ELL: WFL_06805(puuC)
ELP: P12B_c1794(puuC)
EAL: EAKF1_ch0118c(puuC)
ESZ: FEM44_21600(puuC)
ERUY: OSH18_01840(puuC)
SFL: SF1305(aldH)
SFX: S1387(aldH)
SFV: SFV_1314(aldH)
SFE: SFxv_1478(puuC)
SFN: SFy_1874
SFS: SFyv_1932
SFT: NCTC1_01380(puuC)
SSN: SSON_1840(aldH)
SBO: SBO_1762(aldH)
SBC: SbBS512_E1536(puuC)
ENC: ECL_02229
ECHG: FY206_11395(puuC)
EBG: FAI37_19225(puuC)
ENZ: G0034_09770(puuC)
ENB: ELK40_10320(puuC)
EQU: OM418_09760(puuC)
EPU: QVH39_10210(puuC)
ESA: ESA_02082
CSK: ES15_2238(puuC)
CTU: CTU_18830(puuC)
KPN: KPN_01018
KPU: KP1_2002
KPP: A79E_3215
KPR: KPR_3504(puuC)
KPJ: N559_3269
KPX: PMK1_03358(puuC)
KPNU: LI86_16985
KPNK: BN49_2106(puuC)
KVA: Kvar_3361
KPE: KPK_1801 KPK_3542(puuC)
KOX: KOX_16920
KOE: A225_2231
KLW: DA718_17655(puuC)
KAR: LGL98_16135(puuC)
KGR: JJJ10_17605(puuC)
KLP: GUC22_16580(puuC)
RTG: NCTC13098_00943(puuC_1) NCTC13098_04769(puuC_2)
CRO: ROD_03591(puuC)
CPOT: FOB25_06255(puuC)
CITZ: E4Z61_12085(puuC)
CARS: E1B03_06240(puuC)
CIX: M4I31_18400(puuC)
CIB: HF677_018375(puuC)
CITR: GUC46_18335(puuC)
BSEL: RHD99_09160(puuC)
YRE: HEC60_09615(puuC)
SGOE: A8O29_008290(puuC)
PSGC: G163CM_17480(puuC)
TOE: QMG90_13655(puuC)
EBF: D782_2778
EBB: F652_548
SMAR: SM39_1528(puuC) SM39_1949
SMAC: SMDB11_1338(puuC)
SMW: SMWW4_v1c20840(puuC)
SPE: Spro_2065
SRL: SOD_c18770(puuC)
SPLY: Q5A_010385(puuC)
SERF: L085_18345
SQU: E4343_05890(puuC)
SFJ: SAMEA4384070_2122(puuC)
SOF: NCTC11214_04761(puuC_3)
SURI: J0X03_13580(puuC)
SENP: KHA73_10445(puuC)
SNEM: NLX84_10505(puuC)
SNEV: OI978_22840(puuC)
SGRI: SGBXF1_02081(puuC)
TPTY: NCTC11468_02302(puuC_2)
PSI: S70_20145
PSX: DR96_2928
PRG: RB151_020650(puuC)
PHEI: NCTC12003_02199(puuC)
PRJ: NCTC6933_01768(puuC)
VPA: VP1777
VPB: VPBB_1634
VAG: N646_0405
ELUX: BTN50_0123
PAU: PA14_02680(aldH) PA14_09710(aldH)
PNC: NCGM2_0225(aldH) NCGM2_5393(aldH)
PAEB: NCGM1900_0210(aldH) NCGM1900_0765(aldH)
PCQ: PcP3B5_01250(puuC_1) PcP3B5_28650(puuC_2)
PPU: PP_2589
PPF: Pput_3127
PPI: YSA_00386
PPX: T1E_0370(puuC)
PPUT: L483_10470
PPUD: DW66_2399
PMON: X969_09030
PMOT: X970_08690
PVD: CFBP1590__2408(puuC)
PFL: PFL_3523
PPRC: PFLCHA0_c35640(puuC2)
PPRO: PPC_3677
PFB: VO64_0192
PMAN: OU5_4250
PMUD: NCTC8068_02033(puuC_1) NCTC8068_02361(puuC2)
PEN: PSEEN2886
PPUU: PputUW4_04746(puuC2)
PKC: PKB_0176(puuc1)
PCHP: C4K32_3372
PSEM: TO66_17050
PSEC: CCOS191_2333(puuC1) CCOS191_3971(puuC2)
PSOS: POS17_3661
PMAO: PMYSY11_4385(puuC)
PDW: BV82_2978
PSEP: C4K39_5515
PTAE: NCTC10697_03730(puuC_2)
PSOA: PSm6_23270
PALL: UYA_11710
PSTT: CH92_04415
MAD: HP15_943
PALI: A3K91_1186
AGU: AS4_22270
MCUN: NCTC10297_01222(puuC)
SON: SO_3496(gabD)
SDN: Sden_3034
SFR: Sfri_3021
SAZ: Sama_2648
SBL: Sbal_1093
SLO: Shew_0967
SSE: Ssed_1045
SPL: Spea_0937
SHL: Shal_0987
SWD: Swoo_1115
SWP: swp_4177
SPSW: Sps_02564
SKH: STH12_02539(puuC)
SCAA: TUM17387_29380(gabD)
CPS: CPS_2053
GAI: IMCC3135_02520(puuC_1) IMCC3135_09185(puuC_2) IMCC3135_30570(puuC_3)
HCH: HCH_03162
HEL: HELO_1453(puuC3) HELO_3918(puuC2)
HAM: HALO4281
HAAH: HALA3H3_430024(puuC) HALA3H3_490023(puuC)
NZO: SAMEA4504057_0101(puuC)
NCI: NCTC10296_00379(puuC)
LHK: LHK_02213
RSO: RSc2110(aldH)
RSE: F504_2063
RSC: RCFBP_10754(betB)
RSM: CMR15_11262(betB)
RSY: RSUY_07690(puuC_1)
CNC: CNE_BB1p01420(puuC)
RME: Rmet_1623(puuC)
CTI: RALTA_A1429(puuC)
CGD: CR3_3236(putA)
BPS: BPSS0473
BPSE: BDL_3700
BPSM: BBQ_5722
BPSU: BBN_3874
BPSD: BBX_5537
BPK: BBK_5679
BPSH: DR55_4878
BPSA: BBU_5573
BPSO: X996_4628
BUT: X994_4146
BTQ: BTQ_5225
BTJ: BTJ_3856
BTZ: BTL_4710
BTD: BTI_4309
BTV: BTHA_5517
BTHE: BTN_4349
BTHM: BTRA_4615
BTHA: DR62_4398
BTHL: BG87_4682
BOK: DM82_4572
BOC: BG90_6020
BSAV: WS86_21005
BVE: AK36_924
BCJ: BCAL0603(puuC)
BCEW: DM40_587
BCEO: I35_3065(puuC) I35_7818
BMJ: BMULJ_00248(puuC)
BMU: Bmul_2984
BMK: DM80_1933
BCED: DM42_2019
BDL: AK34_119
BUB: BW23_1895
BLAT: WK25_14475
BTEI: WS51_25265
BSTG: WT74_15765
BGU: KS03_3283
BGO: BM43_295
BUK: MYA_2743
BGP: BGL_1c26770(puuC)
BURT: BTHE68_69710(dhaL)
BFN: OI25_6720
PDIO: PDMSB3_2209.1(puuC)
PLG: NCTC10937_02140(puuC_2)
CABK: NK8_58880
BPE: BP2303
BPC: BPTD_2262
BPER: BN118_0765
BPET: B1917_2211
BPEU: Q425_16080
BPAR: BN117_1752
BPA: BPP1569(aldH) BPP2426
BBR: BB1875 BB2647(aldH)
BPT: Bpet2339(aldH)
BAV: BAV2204(aldH)
BHO: D560_3594
BHM: D558_3570
BHZ: ACR54_02294(puuC_1) ACR54_02961(puuC_3)
BTRM: SAMEA390648703042(aldH)
AXY: AXYL_03090(puuC)
AXX: ERS451415_02058(puuC_1)
PUT: PT7_0371
AFQ: AFA_03990
RFR: Rfer_0356
LIH: L63ED372_01614(puuC_1)
APET: ToN1_44710(aldA7)
NTU: NTH_01472(puuC)
MES: Meso_0566
SAME: SAMCFNEI73_Ch3112(ald)
ATU: Atu3959(dhaL)
AVV: RvVAT039_pl04540(dhaL)
AVI: Avi_7257(dhaL)
RET: RHE_PF00397(dhaL)
REC: RHECIAT_PC0000578(dhaL)
RLE: pRL120529
RLG: Rleg_4835
RHL: LPU83_1791(dhaL)
ARA: Arad_4300(dhaL) Arad_8144(dhaL)
NEN: NCHU2750_34000(puuC)
BMEL: DK63_3120
BMEE: DK62_2279
BMF: BAB2_1130
BABO: DK55_3078
BABR: DO74_2475
BABT: DK49_3174
BABB: DK48_2719
BABU: DK53_3163
BABS: DK51_2645
BABC: DO78_2994
BMS: BRA1171
BSZ: DK67_3119
BOV: BOV_A1074
BCS: BCAN_B1202(aldA)
BCAR: DK60_2856
BCAS: DA85_16140
BPV: DK65_2487
BEL: BE61_66840(betB)
RPD: RPD_0049
XAU: Xaut_2725
MIND: mvi_63890
HDN: Hden_0974
HMC: HYPMC_2755(puuC) HYPMC_3960(puuC)
PLEO: OHA_1_02861(puuC)
LABT: FIU93_04260(puuC1) FIU93_12395(puuC2)
CCR: CC_3141
CAK: Caul_3955
CSE: Cseg_0813
ASTD: ATDW_06430
ASTM: MMA231_01531(puuC)
RUT: FIU92_12405(puuC1) FIU92_20860(puuC3)
JAN: Jann_3507
RFU: ROLI_013350(puuC_2) ROLI_013830(puuC_3)
PGA: PGA1_c32250(puuC)
PGL: PGA2_c00450(puuC)
PGD: Gal_00023
PHP: PhaeoP97_03886(puuC)
PPIC: PhaeoP14_00023(puuC)
OTM: OSB_15690(puuC)
LAQU: R2C4_13335
MALG: MALG_01149
SPSE: SULPSESMR1_00275(puuC)
RID: RIdsm_00418(puuC_1) RIdsm_00973(puuC_2) RIdsm_01452(puuC_4) RIdsm_01461(gbsA_3)
ROH: FIU89_15285(puuC1) FIU89_17870(puuC2)
LALG: LentiSH36_00244(puuC)
RSP: RSP_3533 RSP_4003(dhaL)
PDE: Pden_4752
LVS: LOKVESSMR4R_00429(puuC)
PAMO: BAR1_11990
SWI: Swit_1587
SPHD: HY78_18020
SPHM: G432_10310
SPKC: KC8_12730
RRU: Rru_A0298
RRF: F11_01505
TMO: TMO_1026(puuC) TMO_b0414(puuC)
PUB: SAR11_0796(aldH)
DDS: Ddes_1689
DEK: DSLASN_24290(dhaL)
MVQ: MYVA_5916(aldH)
MMAG: MMAD_17970
MAIC: MAIC_05520
MHEV: MHEL_28000
CHAD: CHAD_12300(puuC)
TPR: Tpau_0386
SHY: SHJG_1780
SDV: BN159_0468(puuC)
SFK: KY5_2591
SGE: DWG14_00338(puuC)
MOY: CVS54_03807(puuC)
AUW: AURUGA1_01419(puuC)
MPH: MLP_24600
NCX: Nocox_06675(puuC)
AMD: AMED_6208(puuC)
AMYY: YIM_45840(puuC4)
AMYZ: HUW46_07216(puuC_2)
KAL: KALB_2084
KUT: JJ691_23950(puuC_1) JJ691_46930(puuC_2)
 » show all
Reference
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
  Sequence
[eco:b1300]
Reference
  Authors
Jo JE, Mohan Raj S, Rathnasingh C, Selvakumar E, Jung WC, Park S
  Title
Cloning, expression, and characterization of an aldehyde dehydrogenase from Escherichia coli K-12 that utilizes 3-Hydroxypropionaldehyde as a substrate.
  Journal
Appl Microbiol Biotechnol 81:51-60 (2008)
DOI:10.1007/s00253-008-1608-x
  Sequence
[eco:b1300]
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