KEGG ORTHOLOGY: K09866

ORTHOLOGY: K09866

Entry

K09866 KO

Name

AQP4

Definition

aquaporin-4

Pathway

ko04962

Vasopressin-regulated water reabsorption

ko04976

Bile secretion

Disease

H01491

Neuromyelitis optica

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    K09866  AQP4; aquaporin-4
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    K09866  AQP4; aquaporin-4
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K09866  AQP4; aquaporin-4
Transporters [BR:ko02000]
Other transporters
  Aquaporins and small neutral solute transporters
   Aquaporins
    K09866  AQP4; aquaporin-4

Other DBs

GO:

0015250

TC:

1.A.8

Genes

HSA:

361(AQP4)

PTR:	455350(AQP4)

PPS:	100969962(AQP4)

GGO:	101144332(AQP4)

PON:	100448265(AQP4)

NLE:	100595377(AQP4)

MCC:	703773(AQP4)

MCF:	101866200(AQP4)

CSAB:

103222600(AQP4)

CATY:

105592627(AQP4)

PANU:

101015807(AQP4)

RRO:	104676057(AQP4)

RBB:	108520539(AQP4)

TFN:	117064031(AQP4)

CJC:	100409781(AQP4)

SBQ:	101038415(AQP4)

MMUR:

105857809(AQP4)

MMU:	11829(Aqp4)

MCAL:

110284663(Aqp4)

MPAH:

110333146(Aqp4)

RNO:	25293(Aqp4)

MCOC:

116086868(Aqp4)

MUN:	110563487 110563489

CGE:	100770342(Aqp4)

PLEU:

114708621(Aqp4)

NGI:	103745690(Aqp4)

HGL:	101701386(Aqp4)

CCAN:

109695631(Aqp4)

OCU:	100008646(AQP4)

TUP:	102489928(AQP4)

CFA:	612628(AQP4)

VVP:	112925707(AQP4)

VLG:	121490407(AQP4)

AML:	100481467(AQP4)

UMR:	103663180(AQP4)

UAH:	113253308(AQP4)

ORO:	101367786(AQP4)

ELK:

111142638

MPUF:

101688133(AQP4)

EJU:	114205089(AQP4)

MLX:	118004472(AQP4)

FCA:	101081006(AQP4)

PTG:	102961822(AQP4)

PPAD:

109276462(AQP4)

AJU:	106984180(AQP4)

HHV:	120220813(AQP4)

BTA:	281008(AQP4)

BOM:	102267816(AQP4)

BIU:	109577908(AQP4)

BBUB:

102389159(AQP4)

CHX:	102186073(AQP4)

OAS:	443268(AQP4)

ODA:	120881162(AQP4)

SSC:	100126277(AQP4)

CFR:	102506157(AQP4)

CDK:	105086618(AQP4)

BACU:

103017635(AQP4)

LVE:	103079856(AQP4)

OOR:	101269964(AQP4)

DLE:	111181492(AQP4)

PCAD:

102982008(AQP4)

ECB:	100051905(AQP4)

EPZ:	103541007(AQP4)

EAI:	106822947(AQP4)

MYB:	102258851(AQP4)

MYD:	102766346(AQP4)

MMYO:

118663665(AQP4)

MNA:	107524200(AQP4)

HAI:	109389209(AQP4)

DRO:	112322551(AQP4)

SHON:

118977371(AQP4)

AJM:	119036175(AQP4)

MMF:	118618520(AQP4)

PALE:

102893769(AQP4)

RAY:	107518431(AQP4)

MJV:	108391572(AQP4)

LAV:	100676682(AQP4)

TMU:

101353955

MDO:	100010466(AQP4)

SHR:	100928687(AQP4)

PCW:	110195804(AQP4) 110211128

OAA:	100073374(AQP4) 114814571

GGA:	421088(AQP4)

PCOC:

116242168(AQP4)

MGP:	100542522(AQP4)

CJO:	107310129(AQP4)

NMEL:

110394498(AQP4)

APLA:

101798538(AQP4)

ACYG:

106037615(AQP4)

TGU:	100232616(AQP4) 115491449

LSR:	110477091 110482380(AQP4)

SCAN:

103827157(AQP4)

PMOA:

120512116(AQP4)

GFR:	102042449(AQP4)

FAB:	101812890(AQP4)

PHI:	102112835 102113417(AQP4)

PMAJ:

107199208 107200384(AQP4)

CCAE:

111924916(AQP4)

CCW:	120409727(AQP4)

ETL:	114059283(AQP4) 114070784

FPG:	101911125(AQP4)

FCH:	102058129(AQP4)

CLV:	102090423(AQP4)

EGZ:	104134139(AQP4)

NNI:	104018141(AQP4)

ACUN:

113476724(AQP4)

PADL:

103923157(AQP4)

AAM:	106482887(AQP4)

ASN:	102384737(AQP4)

AMJ:	102574124 102575754(AQP4)

CPOO:

109318196(AQP4) 109322938

GGN:	109304047(AQP4)

PSS:	102444761(AQP4)

CMY:	102942484(AQP4) 119564332

CPIC:

101951003(AQP4) 103306703

TST:	117873436(AQP4)

CABI:

116835844(AQP4)

ACS:	100556774(aqp4) 107982256

PVT:	110074923(AQP4)

PBI:	103061950(AQP4) 112540642

PMUR:

107290364(AQP4) 114922830

TSR:	106550156(AQP4)

PGUT:

117662771 117672728(AQP4)

PMUA:

114600664(AQP4)

ZVI:	118081586 118090316(AQP4)

GJA:	107124351(AQP4)

XLA:	100174805(aqp4.L) 108695273(aqp4.S) 108695306 108695362(XB5993457.S) 108707549 108718588(XB5993457.L) 108718791

XTR:	100216133 100487371(aqp4) 100487834 101733960

NPR:	108785575(AQP4) 108791512 108796507 108798868

DRE:	101885864 445293(aqp4)

SRX:	107723431 107746324 107750891

SANH:

107684806 107696959 107701479

SGH:	107561047 107572142 107601327

CCAR:

109056233 109058681 109058964 109113392(aqp4)

CAUA:

113037770 113063265 113070254

IPU:	108257544 108267324(aqp4) 108275684

PHYP:

113526768 113530889 113545298

AMEX:

103025508 103027636 103030167

EEE:	113585509(aqp4) 113591474

TRU:	101062510 101067990 115246521

TNG:	GSTEN00028331G001

LCO:	104918303(aqp4) 104919660 104922760

NCC:	104951673 104952132 104957666(aqp4)

ELY:	117254276 117258043 117263252

PLEP:

121937622 121946417 121951353

SLUC:

116046063(aqp4) 116062178

GAT:	120816586(aqp4) 120828886

MSAM:

119902064(aqp4) 119905109

CUD:	121512351 121518019 121520167

MZE:	101468604 101472599(aqp4) 101481904

ONL:	100698963 100708036 102077241

OAU:	116310904 116316967 116333079

OLA:	101156496 101164753(aqp4)

OML:	112147110(aqp4) 112158746

XMA:	102222608 102225333(aqp4)

XCO:	114143474 114146035(aqp4)

XHE:	116718295 116721256(aqp4)

PRET:

103467615 103479565(aqp4)

CVG:	107083353(aqp4) 107090264

NFU:	107383930(aqp4) 107391160

KMR:	108232003 108239595(aqp4)

ALIM:

106516763 106534081(aqp4)

AOCE:

111580249(aqp4) 111583798 111588756

CSEM:

103385440 103396337(aqp4)

POV:	109635114 109637076(aqp4)

LCF:	108883430(aqp4) 108885719 108900219 108900678

SDU:	111217272 111231044(aqp4)

SLAL:

111670488(aqp4) 111671550

XGL:	120790911 120799022 120804269

HCQ:	109521284(aqp4) 109528567

BPEC:

110157741(aqp4) 110164499

MALB:

109957707(aqp4) 109966129

SASA:

106569173 106571939 106584191 106599701

OTW:	112215788 112245526 112246652 112260567(aqp4)

OMY:	110508278 110521743 110530421 110532022

SALP:

111956343 111966065 111979614

ELS:	105011881 105018773(aqp4) 106024587

SFM:	108918195 108931592(aqp4) 108937509

PKI:	111837526 111845954 111851648(aqp4)

LOC:	102683527(aqp4) 102688903

PSPA:

121307151 121313488(aqp4)

ARUT:

117400785 117401000 117966998

LCM:	102367428(AQP4)

CMK:	103173385 103179707(aqp4)

RTP:	109918086(aqp4)

BFO:	118417702 118420961

SCLV:

120329381

SPU:	594743 755571

APLC:

110975713 110983004 110985065

SKO:	100303579(aqp) 100367627 100372014 100377429 100378070 102806524

APLN:

PPYR:

PRAP:

ZCE:

HAW:

TNL:

API:

DNX:

AGS:

RMD:

DCI:

FCD:	110848019 110858925

HAME:

121866246 121871147

ISC:	IscW_ISCW019611

DSV:	119433655 119465522

RSAN:

119374236 119377683

RMP:	119176409 119176714

VDE:	111244052 111246557

VJA:	111261846 111263402

TUT:

107366212

DPTE:

113798384 113799272

CSCU:

111622545 111628744 111630786

PTEP:

107437085 107440203

SDM:	118182197 118182502 118194852 118198981

HRO:	HELRODRAFT_113524 HELRODRAFT_154942 HELRODRAFT_165272 HELRODRAFT_185178 HELRODRAFT_193953 HELRODRAFT_95007

LGI:	LOTGIDRAFT_145722 LOTGIDRAFT_162143 LOTGIDRAFT_170145 LOTGIDRAFT_185787 LOTGIDRAFT_94507

PCAN:

112553398 112556875 112562992 112577046 112577061

BGT:	106050534 106052870 106070611 106073175 106074738 106077953

GAE:	121378038 121385002 121388872 121388918 121389089 121389475 121389570

CRG:	105336510 105336511 105340657 105346619

MYI:	110441783 110449939 110452708 110453418 110453612

PMAX:

117322168 117337617 117338387

OBI:	106876928 106878504 106881931

LAK:	106151741 106152959 106153112 106153621 106158020 106158727 106158738 106158783 106159435 106159567 106160552 106160553 106164262 106174316 106174325 106178994

EGL:	EGR_04157 EGR_04164

ATEN:

116287562 116287867 116289281 116294216

ADF:	107354418 107354423

AMIL:

114966914

PDAM:

113686814

SPIS:

111330173 111330181 111338307

DGT:

HMG:

CPAP:

CIT:

PVY:

TCC:	18607623 18607624

GRA:	105762901 105762902

GHI:	107902020 107917605 107921840 107927831 107947405

GAB:	108477378 108477976

DZI:	111308247 111308779

EGR:

104418907

GMX:	100794978 100797262(XIP1-1) 100804160(XIP1-2)

GSJ:	114373900 114380339

PVU:	PHAVU_011G025700g PHAVU_011G025800g

VRA:	106756320 106778217

VAR:	108338861 108340061

VUN:	114169286 114169287

APRC:

113866042

MTR:	MTR_4g075570 MTR_4g075590

CAM:

101502680

LJA:	Lj0g3v0086119.1(Lj0g3v0086119.1) Lj3g3v3541750.1(Lj3g3v3541750.1)

ADU:

107493487

AIP:	107629592 107646799

AHF:	112698154 112737136 112758013

LANG:

109363459

RCN:	112169069 112174658

PPER:

PMUM:

PAVI:

PDUL:

MDM:	103414943 114827618

PXB:	103930326 103948868 103958477

ZJU:

MNT:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:	107262414 8258928 8278125 8278126

JCU:

105643848

HBR:	110659180 110659185

MESC:

110625620 110625623 110625984

POP:

7494273

PEU:

105141427

PALZ:

118040530 118058766 118058767

JRE:	108986931 108987002

QSU:	112001998 112002020 112002041 112008441

QLO:	115967001 115968633

TWL:	119982193 119992300

VVI:	100241797 104878514

VRI:	117910513 117911211

NTA:	107808657 107809188

NSY:

NTO:

NAU:

HAN:

LSV:

CCAV:

DCR:

CSIN:

BVG:

SOE:

CQI:	110718599 110739935

PSOM:

113291308

PPP:

112285589

ACAN:

ACA1_061930

NGR:	NAEGRDRAFT_78300

NMR:

Nmar_0561

NIR:	NSED_02835

NKR:	NKOR_02900

NID:	NPIRD3C_1713

NIN:	NADRNF5_1619

NIW:	Nisw_02060

NCL:	C5F47_02885

NCT:	NMSP_1109(aqpM_1)

CSY:	CENSYa_0190

NGA:	Ngar_c20910

NEV:

NTE_01609

NBV:

T478_0489

TAH:	SU86_003280

NDV:

NDEV_0562

» show all

Reference

PMID:7559426

Authors

Yang B, Ma T, Verkman AS

Title

cDNA cloning, gene organization, and chromosomal localization of a human mercurial insensitive water channel. Evidence for distinct transcriptional units.

Journal

J Biol Chem 270:22907-13 (1995)
DOI:10.1074/jbc.270.39.22907

Sequence

[hsa:361]

Reference

PMID:19085041

Authors

Ishibashi K, Hara S, Kondo S

Title

Aquaporin water channels in mammals.

Journal

Clin Exp Nephrol 13:107-17 (2009)
DOI:10.1007/s10157-008-0118-6

LinkDB

DBGET integrated database retrieval system