KEGG ORTHOLOGY: K10278

ORTHOLOGY: K10278

Entry

K10278                      KO

Symbol

FBXL12

Name

F-box and leucine-rich repeat protein 12

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K10278  FBXL12; F-box and leucine-rich repeat protein 12
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
  Multi subunit type E3
   SCF complex
    Target recognizing subunit (F-box)
     K10278  FBXL12; F-box and leucine-rich repeat protein 12

Genes

HSA:	54850(FBXL12)

PTR:	455688(FBXL12)

PPS:	100984949(FBXL12)

GGO:	101152391(FBXL12)

PON:	100459856(FBXL12)

PPYG:

129019320(FBXL12)

NLE:	100590688(FBXL12)

HMH:	116478422(FBXL12)

SSYN:

129460567(FBXL12)

MCC:	710855(FBXL12)

MCF:	102129161(FBXL12)

MTHB:

126942713

MNI:	105478756(FBXL12)

CSAB:

103233877(FBXL12)

CATY:

105601421(FBXL12)

PANU:

101011757(FBXL12)

TGE:	112613330(FBXL12)

MLEU:

105549596(FBXL12)

RRO:	104670499(FBXL12)

RBB:	108534490(FBXL12)

TFN:	117076064(FBXL12)

PTEH:

111527752(FBXL12)

CANG:

105520891(FBXL12)

CJC:	100395307(FBXL12)

SBQ:	101049537(FBXL12)

CIMI:

108283604(FBXL12)

ANAN:

105706197(FBXL12)

CSYR:

103260542(FBXL12)

MMUR:

105885611(FBXL12)

LCAT:

123635099(FBXL12)

PCOQ:

105807965(FBXL12)

OGA:	100965122(FBXL12)

MMU:	30843(Fbxl12)

MCAL:

110301646(Fbxl12)

MPAH:

110327883(Fbxl12)

RNO:	313782(Fbxl12)

MCOC:

116072984(Fbxl12)

ANU:	117713770(Fbxl12)

ASYL:

127689376(Fbxl12)

MUN:	110557849(Fbxl12)

CGE:	100764456(Fbxl12)

MAUA:

101831560(Fbxl12)

PROB:

127231248(Fbxl12)

PLEU:

114695192(Fbxl12)

MORG:

121451874(Fbxl12)

MFOT:

126490509

AAMP:

119810476(Fbxl12)

NGI:	103734310(Fbxl12)

HGL:	101707451(Fbxl12)

CPOC:

100726883(Fbxl12)

CCAN:

109687751(Fbxl12)

DORD:

105999076(Fbxl12)

DSP:	122119719(Fbxl12)

PLOP:

125348763(Fbxl12)

NCAR:

124968771

MMMA:

107145160(Fbxl12)

ITI:	101959747(Fbxl12)

OCU:

100347448

OPI:	101518899(FBXL12)

TUP:	102501195(FBXL12)

GVR:	103609452(FBXL12)

CFA:	484965(FBXL12)

CLUD:

112666464(FBXL12)

VVP:	112909685(FBXL12)

VLG:	121494190(FBXL12)

NPO:	129521335(FBXL12)

AML:	100471692(FBXL12)

UMR:	103678741(FBXL12)

UAH:	113242965(FBXL12)

UAR:	123777655(FBXL12)

ELK:

111162482

LLV:

125085099

MPUF:

101690865(FBXL12)

MNP:	132010949(FBXL12)

MLK:	131823491(FBXL12)

NVS:	122909754(FBXL12)

ORO:	101370406(FBXL12)

EJU:	114197615(FBXL12)

ZCA:	113918723(FBXL12)

MLX:	118005317(FBXL12)

NSU:	110593912(FBXL12)

LWW:	102737898(FBXL12)

FCA:	101087382(FBXL12)

PYU:	121013947(FBXL12)

PCOO:

112852935(FBXL12)

PBG:	122486838(FBXL12)

PVIV:

125160919(FBXL12)

LRUF:

124524669

LGF:	123605244(FBXL12)

AJU:

106989313

PTG:	102956169(FBXL12)

PPAD:

109254137(FBXL12)

PUC:

125930572

PLEZ:

122213934(FBXL12)

HHV:	120244415(FBXL12)

BTA:	617304(FBXL12)

BOM:	102284239(FBXL12)

BIU:	109561567(FBXL12)

BBUB:

102406305(FBXL12)

BBIS:

104979850(FBXL12)

CHX:	102177970(FBXL12)

OAS:	101110231(FBXL12)

BTAX:

128051236(FBXL12)

CSUM:

138086120(FBXL12)

ODA:	120863996(FBXL12)

CCAD:

122440452(FBXL12)

MREE:

136155710(FBXL12)

OVR:	110147033(FBXL12)

MBEZ:

129559026(FBXL12)

SSC:	100513198(FBXL12)

CFR:	102511540(FBXL12)

CBAI:

105068363(FBXL12)

CDK:	105087654(FBXL12)

VPC:	102525453(FBXL12)

BACU:

103000217(FBXL12)

BMUS:

118893366(FBXL12)

LVE:	103074344(FBXL12)

OOR:	101272779(FBXL12)

LALB:

132517654(FBXL12)

DLE:	111166072(FBXL12)

PCAD:

102992630(FBXL12)

PSIU:

116751610(FBXL12)

NASI:

112400255(FBXL12)

ECB:	100058712(FBXL12)

EPZ:	103558076(FBXL12)

EAI:	106834420(FBXL12)

MYB:	102250171(FBXL12)

MYD:	102771156(FBXL12)

MMYO:

118658911(FBXL12)

MDT:	132235091(FBXL12)

MYUM:

139009817(FBXL12)

PKL:	118731213(FBXL12)

EFUS:

103301145(FBXL12)

MNA:	107533251(FBXL12)

DRO:	112301556(FBXL12)

AJM:	119035838(FBXL12)

PDIC:

114503155(FBXL12)

PHAS:

123828495(FBXL12)

MMF:	118615732(FBXL12)

PPAM:

129061365(FBXL12)

HAI:	109391668(FBXL12)

RFQ:	117038542(FBXL12)

PALE:

102878373(FBXL12)

PGIG:

120610903(FBXL12)

PVP:	105305575(FBXL12)

RAY:	107515120(FBXL12)

MJV:	108385473(FBXL12)

TOD:	119240924(FBXL12)

SARA:

101538390(FBXL12)

SFUM:

130029006(FBXL12)

SETR:

126030150 126030151 126030152 126030154 126031344

LAV:	100664951(FBXL12)

TMU:

101361013

ETF:	101639186(FBXL12)

DNM:	101415737(FBXL12)

MDO:	100013889(FBXL12)

GAS:	123256233(FBXL12)

SHR:	105749402(FBXL12)

AFZ:

127544702

PCW:	110214265 110214432

TVP:

118838758

PBRV:

138157511(FBXL12)

OAA:	114807319(FBXL12)

TACU:

119949352(FBXL12)

GGA:	100859027(FBXL12)

PCOC:

116239089(FBXL12)

MGP:	104915720(FBXL12)

CJO:	107307696(FBXL12)

NMEL:

110391936(FBXL12)

APLA:

110352459(FBXL12)

ACYG:

136788240(FBXL12)

CATA:

118261070(FBXL12)

AFUL:

116500057(FBXL12)

TGU:	115496352(FBXL12)

LSR:

110474546

SCAN:

103815698(FBXL12)

PMOA:

120511267(FBXL12)

OTC:	121342137(FBXL12)

PRUF:

121364076(FBXL12)

ATRC:

139594767(FBXL12)

GFR:	102031791(FBXL12)

FAB:	101821338(FBXL12)

OMA:	130256550(FBXL12)

PHI:	102100256(FBXL12)

PMAJ:

107208662(FBXL12)

CCAE:

111933819(FBXL12)

CCW:	104693103(FBXL12)

CBRC:

103612018(FBXL12)

ACOE:

138114689

ETL:	114065414(FBXL12)

ZAB:	106629510(FBXL12)

ZLE:	135451737(FBXL12)

SVG:	106849610(FBXL12)

MMEA:

130580575(FBXL12)

HRT:	120757178(FBXL12)

SATI:

136365780(FBXL12)

CCIC:

134048018(FBXL12)

FPG:	101924600(FBXL12)

CCRI:

104159932(FBXL12)

SHAB:

115603403(FBXL12)

TALA:

116963063(FBXL12)

ACHC:

115348171(FBXL12)

HALD:

104323932(FBXL12)

HLE:	104832588(FBXL12)

AGEN:

126043184

HHAR:

128147413(FBXL12)

GCL:

127028733

EGZ:	104130039(FBXL12)

NNI:	104018410(FBXL12)

PCRI:

104038681(FBXL12)

PCAO:

104050036

AFOR:

103901571(FBXL12)

CBOY:

140645158(FBXL12)

CLV:

102091566

PLET:

104623498(FBXL12)

EHS:	104508924(FBXL12)

CUCA:

104063325(FBXL12)

ACAR:

104525873(FBXL12)

CPEA:

104394781(FBXL12)

RTD:	128901365(FBXL12)

AAM:	106500182(FBXL12)

AROW:

112976955(FBXL12)

DNE:	112992097(FBXL12)

SCAM:

104153913(FBXL12)

ASN:	102388683(FBXL12)

AMJ:	102562832 102563064(FBXL12)

CPOO:

109324661(FBXL12) 109324664

GGN:	109295176 109295182

PSS:	102445867(FBXL12)

CMY:	102945429(FBXL12)

CCAY:

125627603(FBXL12)

DCC:	119845697(FBXL12)

CPIC:

122172510(FBXL12)

TST:	117889012(FBXL12)

CABI:

116825786(FBXL12)

MRV:	120390896(FBXL12)

ACS:	100557702(fbxl12)

ASAO:

132768181(FBXL12)

PVT:	110071494(FBXL12)

SUND:

121920481(FBXL12)

PBI:	103066026(FBXL12)

PMUR:

107287224(FBXL12)

CTIG:

120311162(FBXL12)

PGUT:

117666590(FBXL12)

APRI:

131191732(FBXL12)

PTEX:

113444828(FBXL12)

NSS:	113416133(FBXL12)

VKO:	123024003(FBXL12)

PMUA:

114592881(FBXL12)

PRAF:

128403975(FBXL12)

ZVI:	118078026 118078530(FBXL12)

HCG:	128347839(FBXL12)

GJA:	107124313(FBXL12)

STOW:

125429744(FBXL12)

EMC:	129346400(FBXL12)

XTR:	100135148(fbxl12)

NPR:	108801373(FBXL12)

RTEM:

120933260(FBXL12)

BBUF:

120986361(FBXL12)

BGAR:

122927212(FBXL12)

PWL:	138292903(FBXL12)

MUO:	115466085(FBXL12)

GSH:	117350623(FBXL12)

SRX:	107712915(fbxl12)

SANH:

107704465(fbxl12)

SGH:	107568667(fbxl12)

CCAR:

109058828

CAUA:

113058081(fbxl12)

CGIB:

PTET:

LROH:

OMC:

PPRM:

RKG:

MAMB:

CIDE:

CERY:

MASI:

TROS:

TDW:

MANU:

PDAB:

IPU:

IFU:

PHYP:

113528321(fbxl12)

SMEO:

TFD:

TVC:

CGAR:

NGRA:

TRN:

AMEX:

CMAO:

EEE:	113585552(fbxl12)

CHAR:

105908757

SPIL:

134095950

TRU:	101077118(fbxl12)

TFS:

130531282

TNG:	GSTEN00029245G001

LCO:	104928695(fbxl12)

NCC:	104957022(fbxl12)

TBEN:

117490303

CGOB:

115014239(fbxl12)

PGEO:

GACU:

EMAC:

ELY:

EFO:

PLEP:

SLUC:

116052535(aurkb)

ECRA:

117951913(aurkb)

ESP:

116696499

PFLV:

114563052(fbxl12)

GAT:

PPUG:

AFB:

CLUM:

PSWI:

CANA:

CVE:

MSAM:

119888703(aurkb)

SCHU:

CUD:

SPUL:

LMIX:

ALAT:

ASTR:

MZE:	101478460(fbxl12)

ONL:	100705850(fbxl12)

OLA:	101173637(fbxl12)

OML:

112153108

CSAI:

133446776

XMA:	102237783(fbxl12)

XCO:	114138801(fbxl12)

XHE:	116716623(fbxl12)

PRET:

103471496(fbxl12)

PFOR:

103149570 103149573

PLAI:

106963142(fbxl12)

PMEI:

106905488 106932942

GAF:

122837338

PPRL:

129360386

CVG:	107092910(fbxl12)

CTUL:

119791491

GMU:

124860965

NFU:	107373364 107379313

KMR:

108231216

ALIM:

106525374(fbxl12)

NWH:

AOCE:

EJA:

BFRE:

MCEP:

CSEM:

103390610(fbxl12)

POV:	109631657(fbxl12)

SSEN:

SSOE:

HHIP:

HSP:

PPLT:

SMAU:

LCF:

SDU:	111232683(fbxl12)

SLAL:

111648249(fbxl12)

XGL:

120785636

HCQ:	109515944(fbxl12)

SSCV:

SBIA:

PEE:

PTAO:

BPEC:

110159003(fbxl12)

ENY:

140348598

MALB:

109974532(fbxl12)

BSPL:

114864551

SJO:

128363322

SSCO:

133986072

GMH:	115552140(fbxl12)

SASA:

106600632 106604490

STRU:

115169526 115170714

OTW:	112220539 112258355

OMY:

110489019

OGO:

123993563

ONE:	115130896(fbxl12)

OKI:	109864921 109893044

OKE:

118380943

OMM:	135526570 135556061

OCLA:

139366429

SALP:

111965519 111980937

SNH:	120041842 120047974

CCLU:

121534749 121541167

ELS:	105007429(fbxl12)

OEP:

134032706

SFM:	108928588(fbxl12)

PKI:	111839480(fbxl12)

AANG:

118223064

AROT:

135250032

CCOG:

133124853

LOC:	107076531(fbxl12)

PSPA:

121306595

ARUT:

117404563 117967913

LCM:	102363187(FBXL12)

CMK:

CPLA:

HOC:

LERI:

PMRN:

116952722(FBXL12)

LRJ:	133356665(FBXL12)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

AJJ:	139956446 139982508

APLC:

110977436 110987256

ARUN:

117297425 117297680

AAMU:

139945776 139945803

AFIL:

140137698 140145778 140148024 140151463 140151920 140167264 140170252

SKO:

102809368

PFLL:

139139030

DAM:

107035837

AGIF:

122847465 122848441 122854057 122854058 122854094 122855733

FOC:	113211117 113212318 113212327

TPAL:

117644310 117644945 117652717

PJA:

PCHN:

PCLA:

PTRU:

DSV:	119432650 119436191 119448550 119449324 119450974 125943740

RSAN:

119389901 119390961 119407158

RMP:

119168619

DFR:

124499689

CSCU:

111628529 111634994

CVS:	136971676 136989987

PTEP:

107442895 107450323

ABRU:

129975969

UDV:

129230129

SDM:	118191594 118194428

LPOL:

106472975

LGI:	LOTGIDRAFT_84554

PVUL:

PCAN:

LSAX:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

LLON:

NVE:

EPA:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:

RES:

TAD:	TRIADDRAFT_57270

AQU:

105315997

GTT:	GUITHDRAFT_136745

» show all

Reference

PMID:18660753

Authors

Kim M, Nakamoto T, Nishimori S, Tanaka K, Chiba T

Title

A new ubiquitin ligase involved in p57KIP2 proteolysis regulates osteoblast cell differentiation.

Journal

EMBO Rep 9:878-84 (2008)
DOI:10.1038/embor.2008.125

Sequence

[hsa:54850]

Reference

PMID:23707388

Authors

Mallampalli RK, Kaercher L, Snavely C, Pulijala R, Chen BB, Coon T, Zhao J, Agassandian M

Title

Fbxl12 triggers G1 arrest by mediating degradation of calmodulin kinase I.

Journal

Cell Signal 25:2047-59 (2013)
DOI:10.1016/j.cellsig.2013.05.012

Sequence

[hsa:54850]

LinkDB

DBGET integrated database retrieval system