KEGG ORTHOLOGY: K10583

ORTHOLOGY: K10583

Entry

K10583                      KO

Symbol

UBE2S, E2EPF

Name

ubiquitin-conjugating enzyme E2 S [EC:2.3.2.23]

Pathway

map04120

Ubiquitin mediated proteolysis

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K10583  UBE2S, E2EPF; ubiquitin-conjugating enzyme E2 S
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K10583  UBE2S, E2EPF; ubiquitin-conjugating enzyme E2 S
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.23  E2 ubiquitin-conjugating enzyme
     K10583  UBE2S, E2EPF; ubiquitin-conjugating enzyme E2 S
Ubiquitin system [BR:ko04121]
Ubiquitin-conjugating enzymes (E2)
  Ubiquitin-conjugating enzymes
   K10583  UBE2S, E2EPF; ubiquitin-conjugating enzyme E2 S

Genes

HSA:	27338(UBE2S)

PTR:	456304(UBE2S)

PPS:	100982341(UBE2S)

GGO:	101142760(UBE2S)

PON:	100454520(UBE2S)

NLE:	100600443(UBE2S)

MCC:	700592(UBE2S)

MCF:	102132501(UBE2S)

CSAB:

103235313(UBE2S)

CATY:

105582758(UBE2S)

PANU:

101020692(UBE2S)

TGE:	112613479(UBE2S)

RRO:	104674771(UBE2S)

RBB:	108542511(UBE2S)

TFN:	117091739(UBE2S)

PTEH:

111521104(UBE2S)

CJC:	100391572(UBE2S)

SBQ:	101048628(UBE2S)

CSYR:

103268549(UBE2S)

MMUR:

105863303(UBE2S)

OGA:	100959096(UBE2S)

MMU:	77891(Ube2s)

MCAL:

110298929(Ube2s)

MPAH:

110336635(Ube2s)

RNO:	292588(Ube2s)

MCOC:

116082269 116101567(Ube2s)

MUN:	110561075(Ube2s)

CGE:	100774405(Ube2s)

PLEU:

114687712(Ube2s)

NGI:	103744808(Ube2s)

HGL:	101704537(Ube2s)

CPOC:

100734699(Ube2s)

CCAN:

109696629(Ube2s)

DORD:

105999497(Ube2s)

DSP:	122110639(Ube2s)

NCAR:

124966936

OCU:	100348547(UBE2S)

OPI:	101530321(UBE2S)

TUP:	102502518(UBE2S)

CFA:	403671(UBE2S)

VVP:	112909362(UBE2S)

VLG:	121479864(UBE2S)

AML:	100473141(UBE2S)

UMR:	103680300(UBE2S)

UAH:	113247425(UBE2S)

UAR:	123786937(UBE2S)

ELK:

111139582

LLV:

125089263

MPUF:

101694118(UBE2S)

ORO:	101363237(UBE2S)

EJU:	114202091(UBE2S)

ZCA:	113935876(UBE2S)

MLX:	117997884(UBE2S)

FCA:	101090565(UBE2S)

PYU:	121023438(UBE2S)

PBG:	122493722(UBE2S)

PTG:	102959664(UBE2S)

PPAD:

109259931(UBE2S)

AJU:	106980885(UBE2S)

HHV:	120239641(UBE2S)

BTA:	617703(UBE2S)

BOM:	102278983 106700513(UBE2S)

BIU:	109572919(UBE2S)

BBUB:

102393520(UBE2S)

CHX:	102183816(UBE2S)

OAS:	101120352(UBE2S)

ODA:	120871908(UBE2S)

CCAD:

122420837(UBE2S)

SSC:	110261061(UBE2S)

CFR:	102517552(UBE2S)

CBAI:

105074367(UBE2S)

CDK:	105098783(UBE2S)

VPC:	102544463(UBE2S)

BACU:

103020514(UBE2S)

LVE:	103080183(UBE2S)

OOR:	101272978(UBE2S)

DLE:	111181028(UBE2S)

PCAD:

102981438(UBE2S) 112064788

PSIU:

116743856(UBE2S)

ECB:	100055998(UBE2S)

EPZ:	103562873(UBE2S)

EAI:	106840939(UBE2S)

MYB:	102241725(SHISA7) 102259572 106725613(UBE2S)

MYD:	102762760(UBE2S)

MMYO:

118655184(UBE2S)

MLF:

102429702

MNA:	107541322(UBE2S)

PKL:	118718056(UBE2S)

HAI:	109373738(UBE2S)

DRO:	112313747(UBE2S)

SHON:

118981368(UBE2S)

AJM:	119059969(UBE2S)

PDIC:

114510940(UBE2S)

PHAS:

123813366(UBE2S)

MMF:	118638521(UBE2S)

RFQ:	117034840(UBE2S)

PALE:

102886584(UBE2S)

PGIG:

120598310(UBE2S)

PVP:	105304905(UBE2S)

RAY:	107515422(UBE2S)

MJV:	108388704(UBE2S)

TOD:	119249758(UBE2S)

SARA:

101558003(UBE2S)

LAV:	100672701(UBE2S)

TMU:

101340736

DNM:	101423262(UBE2S)

MDO:	100032761(UBE2S)

GAS:	123255279(UBE2S)

SHR:	100927511(SHISA7) 111720113(UBE2S)

PCW:	110219827(UBE2S)

OAA:	100084095(UBE2S)

GGA:	107050834(UBE2S)

PCOC:

116241336(UBE2S)

CJO:	107307842(UBE2S)

NMEL:

110398120(UBE2S)

LSR:	110481424(UBE2S)

SCAN:

115483879(UBE2S)

PMOA:

120499660 120507897

CCAE:

111943701(UBE2S)

ASN:	102377897(UBE2S)

AMJ:	102565902(UBE2S)

CMY:	102946577(UBE2S)

CPIC:

101950664(UBE2S)

TST:	117870229(UBE2S)

CABI:

116832330(UBE2S)

MRV:	120388601(UBE2S)

ACS:	100555424(ube2s)

PVT:	110081872(UBE2S)

SUND:

121934909(UBE2S)

PBI:	103056547(UBE2S)

PMUR:

107283092 107296953

PGUT:

117666701(UBE2S)

VKO:	123032330(UBE2S)

PMUA:

114582492(UBE2S)

ZVI:	118094831(UBE2S)

GJA:	107113146(UBE2S)

STOW:

125445253(UBE2S)

XLA:	379075(ube2s.S) 403383(ube2s.L)

XTR:	549192(ube2s)

NPR:	108789535(UBE2S)

RTEM:

120915246(UBE2S)

BBUF:

120995295(UBE2S)

BGAR:

122927016(UBE2S)

DRE:	565498(ube2s)

SRX:	107737918 107750012

SANH:

107673048 107692555

SGH:	107549462 107598418

CCAR:

109049636 109105817

CAUA:

113059927 113116347

PPRM:

120470320(ube2s) 120484794

MAMB:

125243657(ube2s)

IPU:	108266886(ube2s)

PHYP:

113542200(ube2s)

SMEO:

124385272(ube2s)

TFD:	113643702(ube2s)

AMEX:

103031438(ube2s)

EEE:	113570596(ube2s)

TRU:	101078240(ube2s)

TNG:	GSTEN00015412G001

LCO:	104929744(ube2s)

NCC:	104960439(ube2s)

CGOB:

115021898(ube2s)

ELY:	117265741(ube2s)

PLEP:

121945642(ube2s)

SLUC:

116049631(ube2s)

ECRA:

117946286(ube2s)

PFLV:

114557267(ube2s)

GAT:	120811059(ube2s)

PPUG:

119198105(ube2s)

MSAM:

119897506(ube2s)

CUD:	121514312(ube2s)

MZE:	101473465(ube2s)

ONL:	100697621(ube2s)

OAU:	116323888(ube2s)

OLA:	101164429(ube2s)

OML:	112143509(ube2s)

XMA:	102221371(ube2s)

XCO:	114142337(ube2s)

XHE:	116717827(ube2s)

PRET:

103478070(ube2s)

PFOR:

103136662(ube2s)

PLAI:

106953530(ube2s)

PMEI:

106925392(ube2s)

GAF:	122830533(ube2s)

CVG:	107088788(ube2s)

CTUL:

119783185(ube2s)

GMU:	124865818(ube2s)

NFU:	107379561(ube2s)

KMR:	108235354(ube2s)

ALIM:

106520523(ube2s)

NWH:	119409980(ube2s)

AOCE:

111575001(ube2s)

CSEM:

103387835(ube2s)

POV:	109633326(ube2s)

SSEN:

122774135(ube2s)

HHIP:

117776176(ube2s)

LCF:	108887289(ube2s)

SDU:	111229996(ube2s)

SLAL:

111663039 111669823(ube2s)

XGL:	120784836(ube2s)

HCQ:	109515258(ube2s)

BPEC:

110163057 110170199

MALB:

109970247(ube2s)

SASA:

106575167(ube2s) 106605770

OTW:	112234889(ube2s) 112236457

OMY:	110508838 110536976(ube2s)

OGO:	123998150(ube2s) 124006266

ONE:	115101097 115124426

SALP:

112071218(ube2s)

SNH:	120030862 120048740

ELS:	105019014(ube2s)

SFM:	108924681(ube2s)

PKI:	111853365(ube2s)

AANG:

118212715(ube2s)

PSPA:

121302395(ube2s)

ARUT:

117410185(ube2s) 117969245

LCM:	102366745(UBE2S)

BFO:

BBEL:

CIN:

SCLV:

SPU:	115922788 577922

APLC:

110980854

SKO:

100373734

DME:	Dmel_CG8188(CG8188)

DER:

6549769

DSE:

6618109

DSI:	Dsimw501_GD17343(Dsim_GD17343)

DYA:	Dyak_GE15576

DAN:

6503846

DSR:	110177596 110178119

DPO:	Dpse_GA22810

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI11085

DNV:

DHE:

DVI:

CCAT:

BOD:

MDE:

SCAC:

LCQ:

CNS:

AME:

ACER:

ALAB:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BPYO:

CCAL:

OBB:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

NVI:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CCIN:

TCA:

DPA:

SOY:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_213886

BANY:

PMAC:

PRAP:

HAW:

TNL:

SLIU:

OFU:

PXY:

API:

DNX:

AGS:

RMD:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

PHU:	Phum_PHUM023410

FOC:

ZNE:

CSEC:

FCD:

DPX:	DAPPUDRAFT_305549

DMK:

PVM:

PJA:

PCHN:

PCLA:

PTRU:

HAZT:

EAF:

LSM:

ISC:	IscW_ISCW013849

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

PTEP:

SDM:

HRO:	HELRODRAFT_181061

LGI:	LOTGIDRAFT_230299

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

MYI:

PMAX:

MMER:

OBI:

OSN:

LAK:	106160341 106161905

SMM:	Smp_180170

SHX:	MS3_0020177

OVI:	T265_04450

EGL:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

TAD:	TRIADDRAFT_53086

AQU:

100636283

ATH:	AT5G05080(UBC22)

ALY:

9307204

CRB:

17882853

CSAT:

104708607 104734511 104768703

EUS:	EUTSA_v10014464mg

BRP:	103846866 103855606

BNA:	106382987 106419169 106428108 106429594 106440657 106442696

BOE:	106315340 106315341 106315591 106331389

RSZ:	108814556 108844134

THJ:	104816492 104823160 104826883

CPAP:

110811264

CIT:

102610911

CIC:	CICLE_v10012469mg

PVY:

MINC:

TCC:

GRA:

GHI:	107938994 121203098

GAB:

108474144

DZI:	111295413 111312143

EGR:

104425416

GMX:	100794952 100801681 100811067

GSJ:	114398033 114400692

PVU:	PHAVU_001G102600g

VRA:

VAR:

VUN:

CCAJ:

APRC:

MTR:	MTR_7g087590

CAM:

101515409

LJA:	Lj1g3v4047170.1(Lj1g3v4047170.1)

ADU:

107494222

AIP:

107604724

AHF:	112696810 112754675

LANG:

109337049 109350317 109358325

FVE:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:	103449919 103454711

PXB:	103936831 103937172

ZJU:

MNT:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

JCU:

HBR:	110654505 110660459 110665745

MESC:

110609519 110622384

POP:	7458884 7495661

PEU:	105136878 105137313

PALZ:

118033154 118052964

JRE:	108988378 108992605

QSU:

112036284

QLO:

115952873

TWL:	119990808 120012433

VVI:

VRI:

SLY:

SPEN:

SOT:

NTA:	107761762 107815172

NSY:

104226783

NTO:

104117060

NAU:

109207502

INI:	109159134 109181707

ITR:	116005576 116028574

SIND:

105155779

OEU:	111365652 111375315 111386262

EGT:	105959949 105976654

SSPL:

121746387 121753080 121795795 121799460

HAN:	110868742 110903856

ECAD:

122579905 122603668

LSV:	111876667 111896887

CCAV:

112511392 112513634

DCR:	108219302 108227282

CSIN:

114276553 114283622 114303510 114321307

BVG:

104889644

SOE:	110775570 110800630

CQI:	110711496 110714761

NNU:

MING:

TSS:

PSOM:

NCOL:

OSA:

DOSA:

Os06t0660700-01(Os06g0660700)

OBR:

102722022

BDI:	100827991 100830783 100831088

ATS:	109766457 109771778 109781765

TDC:	119316325 119322683 119329709 119331350 119336920 119337986

TAES:

123132530 123136603 123144115 123149326 123149328 123157275 123159993 123165575 123167674

SBI:	110431379 8069377

ZMA:	100194137 100384009

SITA:

101786453 101786846

SVS:	117852279 117852280

PVIR:

120671500 120671501 120704128 120704129

PHAI:

112888435 112891164

PDA:	103701486 103707041 120103744 120111277

EGU:	105039316 105050407 105050854

MUS:	103973136 103982038 103983167

DCT:

110114361

PEQ:

110031107

AOF:	109840382 109841370 109849909

ATR:

18426172

SMO:	SELMODRAFT_145850(UBC22-1) SELMODRAFT_160563(UBC22-2)

PPP:

112279060

CRE:	CHLRE_10g430050v5

VCN:	VOLCADRAFT_82625

MNG:

MNEG_0501

CSL:	COCSUDRAFT_30660

CVR:	CHLNCDRAFT_56059

APRO:

F751_4839

OLU:	OSTLU_31651

OTA:	OT_ostta05g01850

BPG:	Bathy06g03750

MIS:	MICPUN_55138

MPP:	MICPUCDRAFT_70237

CME:	CYME_CMS304C

GSL:	Gasu_34890

YLI:	YALI0B03575g

ANI:

AN1159.2

AFM:	AFUA_1G11410

ACT:	ACLA_024260

NFI:	NFIA_014170

AOR:	AO090038000284

ANG:	ANI_1_1840074(An08g03520)

AFV:	AFLA_008773

ALUC:

AKAW2_30676A

ACHE:

ACHE_30221S

APUU:

APUU_50591S

PCS:	Pc13g08770

PDP:	PDIP_30510

TMF:	PMAA_042840

TRG:	TRUGW13939_03047

CIM:	CIMG_06974

CPW:	CPC735_033440

URE:	UREG_05889

PBL:	PAAG_02995

PBN:	PADG_02866

ABE:

ARB_02802

TVE:

TRV_01903

AJE:	HCAG_01821

BGH:	BDBG_03592

PNO:	SNOG_14962

PTE:

PTT_08946

BZE:	COCCADRAFT_38599

BSC:	COCSADRAFT_176618

BOR:	COCMIDRAFT_35039

AALT:

CC77DRAFT_1002586

ZTR:	MYCGRDRAFT_53885

PFJ:	MYCFIDRAFT_28388

BCOM:

BAUCODRAFT_201820

NPA:	UCRNP2_1153

TML:	GSTUM_00007937001

CNE:

CND04010

CNB:

CNBD2310

CNG:	CNAG_01279

CGI:	CGB_D6710W

TMS:	TREMEDRAFT_33323

TASA:

A1Q1_01920

TVS:	TRAVEDRAFT_170804

DSQ:	DICSQDRAFT_90253

PCO:	PHACADRAFT_260998

SHS:	STEHIDRAFT_100596

HIR:	HETIRDRAFT_243460

PSQ:	PUNSTDRAFT_73814

ADL:	AURDEDRAFT_114852

FME:	FOMMEDRAFT_120457

GTR:	GLOTRDRAFT_75886

MRR:	Moror_9434

E1B28_013331

CCI:	CC1G_08719

SCM:	SCHCODRAFT_83230

ABP:	AGABI1DRAFT102225(AGABI1DRAFT_102225)

ABV:	AGABI2DRAFT77005(AGABI2DRAFT_77005)

CPUT:

CONPUDRAFT_66675

SLA:	SERLADRAFT_459162

WSE:	WALSEDRAFT_36211

UMA:	UMAG_10164

PFP:	PFL1_01545

PGR:	PGTG_07160

MLR:	MELLADRAFT_48820

SRE:	PTSG_08103

DDI:	DDB_G0289021(ube2s)

DPP:	DICPUDRAFT_154070

DFA:	DFA_05720(ube2s)

TET:	TTHERM_00547960

PTM:	GSPATT00006954001 GSPATT00012851001 GSPATT00013166001 GSPATT00016708001

SMIN:

v1.2.023170.t1(symbB.v1.2.023170.t1)

PTI:	PHATRDRAFT_5608

FCY:	FRACYDRAFT_207239

TPS:	THAPSDRAFT_18388 THAPSDRAFT_31758

AAF:	AURANDRAFT_5740

PIF:	PITG_06830

PSOJ:

PHYSODRAFT_326520

SPAR:

SPRG_14896

EHX:	EMIHUDRAFT_370211 EMIHUDRAFT_440316

GTT:	GUITHDRAFT_101759 GUITHDRAFT_84623

TBR:	Tb927.2.3720

TBG:	TbgDal_II2010

TCR:	507715.80 511111.50

LMA:	LMJF_33_2770

LIF:	LINJ_33_2910

LDO:	LDBPK_332910

LMI:	LMXM_32_2770

LBZ:	LBRM_15_0920 LBRM_33_3050

LPAN:

LPMP_332890

NGR:	NAEGRDRAFT_3820

TVA:	TVAG_062270

» show all

Reference

PMID:19820702

Authors

Garnett MJ, Mansfeld J, Godwin C, Matsusaka T, Wu J, Russell P, Pines J, Venkitaraman AR

Title

UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit.

Journal

Nat Cell Biol 11:1363-9 (2009)
DOI:10.1038/ncb1983

Sequence

[hsa:27338]

Reference

PMID:20061386

Authors

David Y, Ziv T, Admon A, Navon A

Title

The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.

Journal

J Biol Chem 285:8595-604 (2010)
DOI:10.1074/jbc.M109.089003

Sequence

[hsa:27338]

LinkDB

DBGET integrated database retrieval system