KEGG ORTHOLOGY: K10988

ORTHOLOGY: K10988

Entry

K10988                      KO

Symbol

RAG2

Name

recombination-activating protein 2

Pathway

map04068

FoxO signaling pathway

map05340

Primary immunodeficiency

Disease

H00092

T-B-Severe combined immunodeficiency

H00093

Combined immunodeficiency

H02554

Omenn syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    K10988  RAG2; recombination-activating protein 2
09160 Human Diseases
  09163 Immune disease
   05340 Primary immunodeficiency
    K10988  RAG2; recombination-activating protein 2

Genes

HSA:	5897(RAG2)

PTR:	466490(RAG2)

PPS:	100982621(RAG2)

GGO:	101150280(RAG2)

PON:	100447476(RAG2)

PPYG:

129008566(RAG2)

NLE:	100596220(RAG2)

HMH:	116476343(RAG2)

SSYN:

129484227(RAG2)

MCC:	716837(RAG2)

MCF:	102124625(RAG2)

MTHB:

126936614

MNI:	105471575(RAG2)

CSAB:

103237494(RAG2)

CATY:

105586812(RAG2)

PANU:

101000786(RAG2)

TGE:	112607113(RAG2)

MLEU:

105534669(RAG2)

RRO:	104658367(RAG2)

RBB:	108535563(RAG2)

TFN:	117080230(RAG2)

PTEH:

111521903(RAG2)

CANG:

105510805(RAG2)

CJC:	100396079(RAG2)

SBQ:	101034251(RAG2)

CIMI:

108305746(RAG2)

ANAN:

105717288(RAG2)

CSYR:

103253467 103253468 103263675(RAG2)

MMUR:

105856825(RAG2)

LCAT:

123642605(RAG2)

ERUF:

138384347(RAG2)

PCOQ:

105814562(RAG2)

OGA:	100946435(RAG2)

MMU:	19374(Rag2)

MCAL:

110312575(Rag2)

MPAH:

110319179(Rag2)

RNO:	295953(Rag2)

MCOC:

116090548(Rag2)

ANU:	117703537(Rag2)

ASYL:

127685658(Rag2)

MUN:	110557495(Rag2)

CGE:	100754577(Rag2)

MAUA:

101831269(Rag2)

PROB:

127222198(Rag2)

PLEU:

114710747(Rag2)

PMAV:

102908672(Rag2)

MORG:

121440526 121465446(Rag2)

MFOT:

126504515

AAMP:

119815842(Rag2)

CNL:	130882039(Rag2)

NGI:	103749516(Rag2)

HGL:	101724205(Rag2)

CPOC:

100723894(Rag2)

CCAN:

109693566(Rag2)

DORD:

105988106(Rag2)

DSP:	122117873(Rag2)

DMER:

138833971(Rag2)

PLOP:

125361678(Rag2)

NCAR:

124958024

MMMA:

107135762(Rag2)

ITI:	101955884(Rag2)

OCU:	100328951(RAG2)

OPI:	101517819(RAG2)

OCZ:	121156540(RAG2)

TUP:	102484736(RAG2)

GVR:	103601165(RAG2)

CFA:	483419(RAG2)

CLUD:

112663498(RAG2)

VVP:	112930433(RAG2)

VLG:	121501411(RAG2)

NPO:	129494441(RAG2)

AML:	100484130(RAG2)

UMR:	103659302(RAG2)

UAH:	113264890(RAG2)

UAR:	123799546(RAG2)

ELK:

111150029

LLV:

125079525

MPUF:

101693111(RAG2)

MNP:	132010617(RAG2)

MLK:	131822122(RAG2)

NVS:	122914306(RAG2)

ORO:	101386709(RAG2)

EJU:	114215239(RAG2)

ZCA:	113915401(RAG2)

MLX:	118015563(RAG2)

MANO:

123841386(RAG2)

NSU:	110575731(RAG2)

LWW:	102729348(RAG2)

FCA:	101096513(RAG2)

PYU:	121043531(RAG2)

PCOO:

112865982(RAG2)

PBG:	122483714(RAG2)

PVIV:

125147149(RAG2)

LRUF:

124504702

LGF:	123601606(RAG2)

AJU:

106976929

PTG:	102960720(RAG2)

PPAD:

109279195(RAG2)

PUC:

125934496

PLEZ:

122200657(RAG2)

HHV:	120232542(RAG2)

CCRU:

144242539(RAG2)

BTA:	782387(RAG2)

BOM:	102286731(RAG2)

BIU:	109569898(RAG2)

BBUB:

102397757(RAG2)

BKE:	129629322(RAG2)

BBIS:

104982480(RAG2)

CHX:	102173867(RAG2)

OAS:	101107628(RAG2)

BTAX:

128061013(RAG2)

CSUM:

138092331(RAG2)

ODA:	120876882(RAG2)

CCAD:

122449755(RAG2)

MREE:

136174068(RAG2)

OVR:	110144870(RAG2)

MBEZ:

129554056(RAG2)

SSC:	100151744(RAG2)

CFR:	102519710(RAG2)

CBAI:

105076496(RAG2)

CDK:	105106826(RAG2)

VPC:	102541438(RAG2)

BACU:

103020513(RAG2)

BMUS:

118898741(RAG2)

LVE:	103087961(RAG2)

OOR:	101278031(RAG2)

LALB:

132525189(RAG2)

GMF:	115857532(RAG2)

DDP:	132429177(RAG2)

DLE:	111179768(RAG2)

PCAD:

102991832(RAG2)

PSIU:

116758657(RAG2)

PPHC:

136126679(RAG2)

NASI:

112404536(RAG2)

ECB:	100049881(RAG2)

EPZ:	103560232(RAG2)

EAI:	106837476(RAG2)

MYB:	102253401(RAG2)

MYD:	102765360(RAG2)

MMYO:

118665123(RAG2)

MLF:	102437925(RAG2)

MDT:	132242323(RAG2)

MYUM:

139017866(RAG2)

PKL:	118713122(RAG2)

EFUS:

103290871(RAG2)

MNA:	107531992(RAG2)

DRO:	112303393(RAG2)

SHON:

118983215(RAG2)

AJM:	119036485(RAG2)

PDIC:

114500388(RAG2)

PHAS:

123810225(RAG2)

MMF:	118628979(RAG2)

PPAM:

129080724(RAG2)

HAI:	109381100(RAG2)

RFQ:	117031086(RAG2)

PALE:

102887570(RAG2)

PGIG:

120606113(RAG2)

PVP:	105290064 105290065 105311290

RAY:	107499245(RAG2)

MJV:	108387880(RAG2)

TOD:	119255352(RAG2)

SARA:

101543746(RAG2)

SFUM:

130043450(RAG2)

SETR:

126017638(RAG2)

LAV:	100658016(RAG2)

TMU:

101345843

ETF:	101659442(RAG2)

DNM:	101436508(RAG2)

MDO:	100010149(RAG2)

GAS:	123252944(RAG2)

SHR:	100922847(RAG2)

AFZ:

127539683

PCW:	110192651(RAG2)

TVP:	118852698(RAG2)

PBRV:

138163426(RAG2)

MLAO:

141516535(RAG2)

OAA:	100073666(RAG2)

TACU:

119943965(RAG2)

GGA:	423165(RAG2)

PCOC:

116229119(RAG2)

MGP:	100542788(RAG2)

CJO:	107314705(RAG2)

TPAI:

128086249(RAG2)

LMUT:

125694457(RAG2)

NMEL:

110401223(RAG2)

APLA:

101802914(RAG2)

AACU:

137857757(RAG2)

OJA:	118167519(RAG2)

ACYG:

106044294(RAG2)

CATA:

118250805(RAG2)

AFUL:

116489675(RAG2)

TGU:	100221953(RAG2)

LSR:	110484467(RAG2)

SCAN:

103826721(RAG2)

PMOA:

120512568(RAG2)

OTC:	121344868(RAG2)

PRUF:

121361006(RAG2)

ATRC:

139590697(RAG2)

GFR:	102041336(RAG2)

FAB:	101817082(RAG2)

OMA:	130254078(RAG2)

PHI:	102105553(RAG2)

PMAJ:

107206256(RAG2)

CCAE:

111930102(RAG2)

CCW:	104694107(RAG2)

CBRC:

103620713(RAG2)

ACOE:

138111412(RAG2)

ETL:	114056754(RAG2)

ZAB:	102065190(RAG2)

ZLE:	135448620(RAG2)

ACHL:

103806230(RAG2)

SVG:	106851513(RAG2)

MMEA:

130578104(RAG2)

HRT:	120754437(RAG2)

CFAI:

136292320(RAG2)

CCIC:

134045788(RAG2)

FPG:	101912350(RAG2)

FCH:	102058383(RAG2)

CCRI:

104154751(RAG2)

NNT:	104399309(RAG2)

SHAB:

115607217(RAG2)

ACUN:

113481139(RAG2)

ANOC:

141961965(RAG2)

SURA:

141935880(RAG2)

TALA:

104355617(RAG2)

ACHC:

115334767(RAG2)

HALD:

104324432(RAG2)

HLE:	104843210(RAG2)

AGEN:

126049492

HHAR:

128140219(RAG2)

BBUT:

142032473(RAG2)

GCL:

127017363

CSTI:

104549107(RAG2)

LDI:	104352255(RAG2)

MNB:	103771036(RAG2)

DPUB:

104304788(RAG2)

PPUS:

135179942(RAG2)

AVIT:

104267401(RAG2)

BRHI:

104501384(RAG2)

EGZ:	104134048(RAG2)

NNI:	104009616(RAG2)

PCRI:

104024122(RAG2)

PCAO:

104046868(RAG2)

PARX:

142057734(RAG2)

PADL:

103921678(RAG2)

AFOR:

103901555(RAG2)

FGA:	104069447(RAG2)

CBOR:

142083301(RAG2)

GSTE:

104254404(RAG2)

CBOY:

140653625(RAG2)

MAME:

142409715(RAG2)

CLV:	102084267(RAG2)

CNIC:

135989796(RAG2)

MUI:	104544953(RAG2)

PGUU:

104468495(RAG2)

PLET:

104613858(RAG2)

EHS:	104502945(RAG2)

CMAC:

104473272(RAG2)

CUCA:

104056323(RAG2)

TEO:	104374948(RAG2)

BREG:

104629327(RAG2)

GAME:

129207318(RAG2)

OHA:	104330074(RAG2)

ACAR:

104517799(RAG2)

CPEA:

104388405(RAG2)

CVF:	104295802(RAG2)

RTD:	128909456(RAG2)

CRID:

134515152(RAG2)

LMIC:

141742326(RAG2)

NARQ:

141466126(RAG2)

AAM:	106498365(RAG2)

AROW:

112960918(RAG2)

NPD:	112943551(RAG2)

TGT:	104568689(RAG2)

DNE:	112981784(RAG2)

SCAM:

104152883(RAG2)

ASN:	102367820(RAG2)

AMJ:	102565473(RAG2)

CPOO:

109321600(RAG2)

GGN:	109298947(RAG2)

PSS:	102463895(RAG2)

CIZ:	142015439(RAG2)

CMY:	102938520(RAG2)

CCAY:

125638953(RAG2)

LKP:	140913854(RAG2)

NDS:	141989048(RAG2)

DCC:	119857679(RAG2)

CPIC:

101953357(RAG2)

TST:	117876999(RAG2)

CABI:

116839270(RAG2)

MRV:	120405281(RAG2)

ACS:	100561011(rag2)

ASAO:

132768603(RAG2)

PVT:	110090248(RAG2)

SUND:

121935139(RAG2)

PBI:	103053259(RAG2)

PMUR:

107293335(RAG2)

CTIG:

120301922(RAG2)

TSR:	106556864(RAG2)

PGUT:

117665477(RAG2)

PCAE:

139307861(RAG2)

APRI:

131188938(RAG2)

PTEX:

113438997(RAG2)

NSS:	113410175(RAG2)

VKO:	123026694(RAG2)

PMUA:

114585001(RAG2)

PRAF:

128413606(RAG2)

ZVI:	118085435(RAG2)

HCG:	128336868(RAG2)

GJA:	107114928(RAG2)

STOW:

125427477(RAG2)

EMC:	129324013(RAG2)

XLA:	100037211(rag2.S)

XTR:	100494391(rag2)

NPR:	108787827(RAG2)

RTEM:

120917065(RAG2)

ACAT:

141111946(RAG2)

PADS:

140338093(RAG2)

BBUF:

120980946(RAG2)

BGAR:

122920488(RAG2)

DTC:	141092439(RAG2)

PWL:	138283755(RAG2)

MUO:	115467958(RAG2)

GSH:	117351995(RAG2)

DRE:	30658(rag2)

SRX:	107720771 107750738

SANH:

107670203 107673237

SGH:	107564622 107564623 107581808

CCAR:

109051083

CAUA:

113098356(rag2)

CGIB:

128013708

PTET:

122330334(rag2)

LROH:

127156788(rag2)

GRF:	141301954(rag2)

OMC:	131534976(rag2)

PPRM:

120468291(rag2)

RKG:	130073695(rag2)

MAMB:

125247335(rag2)

CIDE:

127507443

CERY:

137015263(rag2)

MASI:

127435904

TROS:

130552246(rag2)

TDW:	130414636(rag2)

MANU:

129434131(rag2)

PDAB:

135787752(rag2)

IPU:

108275346

IFU:	128618031(rag2)

PHYP:

113529908(rag2)

SMEO:

124392385(rag2)

TFD:	113660194(rag2)

TVC:	132857067(rag2)

CGAR:

128542735(rag2)

NGRA:

132881929(rag2)

TRN:	134320270(rag2)

AMEX:

103046156(rag2)

CMAO:

118811588(rag2)

EEE:	113589165(rag2)

CHAR:

105900788(rag2)

SPIL:

134094505(rag2)

ASAD:

121724552(rag2)

TRU:	101061349(rag2)

TFS:	130536717(rag2)

TNG:	GSTEN00022841G001

LCO:	104925261(rag2)

NCC:	104941237(rag2)

TBEN:

117491594(rag2)

CGOB:

115009965(rag2)

PGEO:

117448290(rag2)

GACU:

117545782(rag2)

EMAC:

134859474(rag2)

ELY:	117262767(rag2)

EFO:	125887447(rag2)

PLEP:

121950514(rag2)

SLUC:

116038597(rag2)

ECRA:

117949483(rag2)

ESP:	116694131(rag2)

PFLV:

114560562(rag2)

GAT:	120809627(rag2) 120812166

PPUG:

119196233(rag2)

AFB:	129108680(rag2)

CLUM:

117732222(rag2)

PSWI:

130195659(rag2)

CANA:

137804286(rag2)

CVE:	137870743(rag2)

MSAM:

119893179(rag2)

SCHU:

122875332(rag2)

EARM:

139286774(rag2)

CUD:	121515451(rag2)

SPUL:

138613243(rag2)

LMIX:

132973237(rag2)

HTC:	141796862(rag2)

ALAT:

119024490(rag2)

ASTR:

137594311(rag2)

PKLU:

139201562(rag2)

MZE:	101481301(rag2)

ONL:	100703785(rag2)

OAU:	116334527(rag2)

OLA:	101169356(rag2)

OML:	112152699(rag2)

CSAI:

133444700(rag2)

XMA:	102231685(rag2)

XCO:	114152620(rag2)

XHE:	116730258(rag2)

PRET:

103466124(rag2)

PFOR:

103133650(rag2) 103133652

PLAI:

106945044(rag2)

PMEI:

106921868(rag2)

GAF:	122835411(rag2)

PPRL:

129362646(rag2)

CVG:	107094313(rag2)

CTUL:

119793032(rag2)

GMU:	124858047(rag2)

NFU:	107388559(rag2)

KMR:	108239938(rag2)

ALIM:

106515591(rag2)

NWH:	119415570(rag2)

AOCE:

111563270(rag2)

EJA:	138206288(rag2)

BFRE:

138622781(rag2)

MCEP:

125015112(rag2)

CSEM:

103380510(rag2)

POV:	109624278(rag2)

SSEN:

122776160(rag2)

SSOE:

131469431(rag2)

HHIP:

117763073(rag2)

HSP:	118109786(rag2)

PPLT:

128444750(rag2)

SMAU:

118315789(rag2)

LCF:

108875221

SDU:	111228686(rag2)

SLAL:

111655325(rag2) 111665854

XGL:	120793454(rag2)

HCQ:	109530317(rag2)

SSCV:

125970823(rag2)

SBIA:

133502250(rag2)

PEE:	133402803(rag2)

PTAO:

133477873(rag2)

BPEC:

110165931(rag2)

ENY:	140349040(rag2)

MALB:

109968739(rag2)

BSPL:

114857051(rag2)

SJO:	128358882(rag2)

SSCO:

133982172(rag2)

TTY:	137183813(rag2)

GMH:	115550915(rag2)

SASA:

106561305(rag2)

STRU:

115197318(rag2)

OTW:	112218682(rag2)

OMY:	110497172(rag2)

OGO:	124035643(rag2)

ONE:	115134152(rag2)

OKI:	109867340(rag2)

OKE:	118395751(rag2)

OMM:	135509235(rag2)

OCLA:

139373296

SALP:

111962441(rag2)

SNH:	120066379(rag2)

SFON:

129862276(rag2)

CCLU:

121532207(rag2)

ELS:	105018379(rag2)

OEP:	134021279(rag2)

SFM:	108942123(rag2)

PKI:	111859495(rag2)

AANG:

118214867(rag2)

AROT:

135242088(rag2)

CCOG:

133111716(rag2)

LOC:	102682206(rag2)

PSPA:

121295047(rag2)

ARUT:

117432347 117434441

PSEX:

120517628(rag2)

LCM:	102361038(RAG2)

CMK:	103174960(rag2)

RTP:	109930494(rag2)

CPLA:

122558035(rag2)

CPUN:

140493784(rag2)

HOC:	132824259(rag2)

SCAU:

119971924(rag2)

LERI:

129705683(rag2)

HAKA:

140729644(rag2)

» show all

Reference

PMID:2360047

Authors

Oettinger MA, Schatz DG, Gorka C, Baltimore D

Title

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination.

Journal

Science 248:1517-23 (1990)
DOI:10.1126/science.2360047

Sequence

[mmu:19374]

Reference

PMID:12045092

Authors

Gellert M

Title

V(D)J recombination: RAG proteins, repair factors, and regulation.

Journal

Annu Rev Biochem 71:101-32 (2002)
DOI:10.1146/annurev.biochem.71.090501.150203

LinkDB

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