KEGG ORTHOLOGY: K11259

ORTHOLOGY: K11259

Entry

K11259                      KO

Symbol

ILVBL, HACL2

Name

2-hydroxyacyl-CoA lyase [EC:4.1.2.-]

Brite

KEGG Orthology (KO) [BR:ko00001]
09190 Not Included in Pathway or Brite
  09191 Unclassified: metabolism
   99980 Enzymes with EC numbers
    K11259  ILVBL, HACL2; 2-hydroxyacyl-CoA lyase

Genes

HSA:	10994(ILVBL)

PTR:	455791(ILVBL)

PPS:	100973856(ILVBL)

GGO:	101147949(ILVBL)

PON:	100454145(ILVBL)

NLE:	100590016(ILVBL)

HMH:	116478612(ILVBL)

MCC:	718086(ILVBL)

MCF:	102123224(ILVBL)

MTHB:

126942221

MNI:	105495883(ILVBL)

CSAB:

103234063(ILVBL)

CATY:

105601603(ILVBL)

PANU:

101002689(ILVBL)

TGE:	112612027(ILVBL)

MLEU:

105540087(ILVBL)

RRO:	104661027(ILVBL)

RBB:	108523073(ILVBL)

TFN:	117074412(ILVBL)

PTEH:

111554359(ILVBL)

CANG:

105519763(ILVBL)

CJC:	100405461(ILVBL)

SBQ:	101039473(ILVBL)

CIMI:

108296603(ILVBL)

CSYR:

103272145(ILVBL)

MMUR:

105867966(ILVBL)

LCAT:

123636824(ILVBL)

PCOQ:

105825089(ILVBL)

OGA:	100965319(ILVBL)

MMU:	216136(Ilvbl)

MCAL:

110303252(Ilvbl)

MPAH:

110326443(Ilvbl)

RNO:	362843(Ilvbl)

MCOC:

116076115(Ilvbl)

ANU:	117696257(Ilvbl)

MUN:	110559872(Ilvbl)

CGE:	100752439(Ilvbl)

MAUA:

101825263(Ilvbl)

PROB:

127216680(Ilvbl)

PLEU:

114686136(Ilvbl)

MORG:

121432435(Ilvbl)

MFOT:

126504085

AAMP:

119807994(Ilvbl)

NGI:	103733578(Ilvbl)

HGL:	101720799(Ilvbl)

CPOC:

100716587(Ilvbl)

CCAN:

109681378(Ilvbl)

DORD:

105994646(Ilvbl)

DSP:	122100270(Ilvbl)

PLOP:

125348867(Ilvbl)

NCAR:

124968702

MMMA:

107145289(Ilvbl)

OCU:

100353484

OPI:	101523801(ILVBL)

TUP:	102500386(ILVBL)

GVR:	103604489(ILVBL)

CFA:	100856083(ILVBL)

CLUD:

112666652(ILVBL)

VVP:	112913150(ILVBL)

VLG:	121495656(ILVBL)

NPO:	129521999(ILVBL)

AML:	100464366(ILVBL)

UMR:	103677179(ILVBL)

UAH:	113248712(ILVBL)

UAR:	123779896(ILVBL)

ELK:

111143983

LLV:

125083305

MPUF:

101674444(ILVBL)

MNP:	132011103(ILVBL)

MLK:	131823670(ILVBL)

NVS:	122909555(ILVBL)

ORO:	101373578(ILVBL)

EJU:	114202199(ILVBL)

ZCA:	113917378(ILVBL)

MLX:	118004920(ILVBL)

NSU:	110574577(ILVBL)

LWW:

102739092

FCA:	101099531(ILVBL)

PYU:	121010923(ILVBL)

PCOO:

112852609(ILVBL)

PBG:	122487025(ILVBL)

PVIV:

125160338(ILVBL)

LRUF:

124524381

PTG:	102970925(ILVBL)

PPAD:

109247509(ILVBL)

PUC:

125929148

AJU:

106982930

HHV:	120239199(ILVBL)

BTA:	506955(ILVBL)

BOM:	102265737(ILVBL) 102266360

BIU:	109561485(ILVBL)

BBUB:

102410437(ILVBL) 112582627

BBIS:

105001909(ILVBL)

CHX:	102189750(ILVBL)

OAS:	101120571(ILVBL)

BTAX:

128051260(ILVBL)

ODA:	120864148(ILVBL)

CCAD:

122440641(ILVBL)

MBEZ:

129558607(ILVBL)

SSC:	100523720(ILVBL)

CFR:	102521829(ILVBL)

CBAI:

105074551(ILVBL)

CDK:	105105143(ILVBL)

VPC:	102525356(ILVBL)

BACU:

102999233(ILVBL)

BMUS:

118892424(ILVBL)

LVE:	103086282(ILVBL)

OOR:	101278347(ILVBL)

DLE:	111166645(ILVBL)

PCAD:

102974353(ILVBL)

PSIU:

116751376(ILVBL)

NASI:

112414757(ILVBL)

ECB:	100147631(ILVBL)

EPZ:	103564210(ILVBL)

EAI:	106839071(ILVBL)

MYB:	102254133(ILVBL)

MYD:	102763669(ILVBL)

MMYO:

118652613(ILVBL)

MLF:	102423918(ILVBL)

PKL:	118706547(ILVBL)

EFUS:

103300914(ILVBL)

MNA:	107534311(ILVBL)

DRO:	112305097(ILVBL)

SHON:

118993454(ILVBL)

AJM:	119061875(ILVBL)

PDIC:

114502411(ILVBL)

PHAS:

123828278(ILVBL)

MMF:	118615374(ILVBL)

PPAM:

129074937(ILVBL)

HAI:	109376073(ILVBL)

RFQ:	117037658(ILVBL)

PALE:

102895541(ILVBL)

PGIG:

120606473(ILVBL)

PVP:	105308253(ILVBL)

RAY:	107517225(ILVBL)

MJV:	108408754(ILVBL)

TOD:	119241058(ILVBL)

SARA:

101547619(ILVBL)

SETR:

126031019(ILVBL)

LAV:	100672817(ILVBL)

TMU:

101356988

ETF:	101641065(ILVBL)

DNM:	101443237(ILVBL)

MDO:	100012422(ILVBL)

GAS:	123255686(ILVBL)

SHR:	100926194(ILVBL)

AFZ:

127545015

PCW:	110196142(ILVBL)

OAA:	100079696(ILVBL)

GGA:	101747528(ILVBL)

PCOC:

116240106(ILVBL)

NMEL:

110391143(ILVBL)

APLA:

119714254(ILVBL)

ACYG:

106049442(ILVBL)

CATA:

118261170(ILVBL)

AFUL:

116500107(ILVBL)

TGU:	115491609(ILVBL)

LSR:	110479077(ILVBL)

PMOA:

120497085(ILVBL)

OTC:	121342703(ILVBL)

OMA:	130263038(ILVBL)

PHI:	102099975(ILVBL)

SVG:	106864173(ILVBL)

HRT:	120747999(ILVBL)

FCH:	102046526(ILVBL)

EGZ:	104129970(ILVBL)

NNI:	104014968(ILVBL)

ACUN:

113490899

AFOR:

103894330(ILVBL)

ACHC:

115348387(ILVBL)

HLE:	104832614(ILVBL)

AGEN:

126042433

GCL:

127028726

CSTI:

104561996(ILVBL)

ACAR:

104526352(ILVBL)

CVF:	104291643(ILVBL)

RTD:	128901503(ILVBL)

CUCA:

104063123(ILVBL)

AAM:	106487490(ILVBL)

AROW:

112960886(ILVBL)

DNE:

112994396

ASN:	102373433(ILVBL)

AMJ:	102575729(ILVBL)

PSS:	102450030(ILVBL)

CMY:	102935709(ILVBL)

CCAY:

125628968(ILVBL)

CPIC:

101932534(ILVBL)

TST:	117889441(ILVBL)

CABI:

116826945(ILVBL)

MRV:	120391066(ILVBL)

ACS:	100561747(ilvbl)

ASAO:

132767997(ILVBL)

PVT:	110077978(ILVBL)

SUND:

121921585(ILVBL)

PBI:	103057443(ILVBL)

PMUR:

107287123

CTIG:

120305073(ILVBL)

TSR:	106538217(ILVBL)

PGUT:

117677546(ILVBL)

APRI:

131189994(ILVBL)

PTEX:

113446876(ILVBL)

NSS:	113419969(ILVBL)

VKO:	123017744(ILVBL)

PMUA:

114587316(ILVBL)

PRAF:

128404616(ILVBL)

ZVI:	118097770(ILVBL)

HCG:	128342532(ILVBL)

GJA:	107112917(ILVBL)

STOW:

125436078(ILVBL) 125437036

EMC:	129345159(ILVBL)

XLA:

108696571

XTR:	100145261(ilvbl)

NPR:	108791773(ILVBL)

RTEM:

120915625(ILVBL)

BBUF:

120998053(ILVBL)

BGAR:

122926802(ILVBL)

MUO:	115457896 115458247

GSH:	117350272(ILVBL)

DRE:	393639(ilvbl)

SRX:	107753009 107758073

SANH:

107669134 107670636

SGH:	107554989 107565096(ilvbl)

CCAR:

109101536

CAUA:

113061758 113073220 113118670

CGIB:

127934199 127977768

PTET:

122323015(ilvbl)

LROH:

127180669(ilvbl)

OMC:	131524935(ilvbl)

PPRM:

120460003(ilvbl)

RKG:	130069995(ilvbl)

MAMB:

125254064(ilvbl)

CIDE:

127499623

MASI:

127416954 127455752

TROS:

130562796(ilvbl)

TDW:	130436025(ilvbl)

MANU:

129419154(ilvbl)

IPU:

108258198

IFU:	128601480(ilvbl)

PHYP:

113524744(ilvbl)

SMEO:

124376609(ilvbl)

TFD:	113647966(ilvbl)

TVC:	132842982(ilvbl)

AMEX:

103023052(ilvbl)

CMAO:

118804029(ilvbl)

EEE:	113585909(ilvbl)

CHAR:

105909688(ilvbl)

TRU:	101069372(ilvbl)

TFS:	130534721(ilvbl)

TNG:	GSTEN00019546G001

LCO:	104940502(ilvbl)

NCC:	104941979(ilvbl)

TBEN:

117470195(ilvbl)

CGOB:

115017295(ilvbl)

PGEO:

117457652(ilvbl)

GACU:

117551683(ilvbl)

EMAC:

134880719(ilvbl)

ELY:	117259156(ilvbl)

EFO:	125889316(ilvbl)

PLEP:

121943777(ilvbl)

SLUC:

116043838(ilvbl)

ECRA:

117941768(ilvbl)

ESP:	116684758(ilvbl)

PFLV:

114552564(ilvbl)

GAT:	120825002(ilvbl)

PPUG:

119215858(ilvbl)

AFB:	129091174(ilvbl)

CLUM:

117741893(ilvbl)

PSWI:

130210558(ilvbl)

MSAM:

119883425(ilvbl)

SCHU:

122879582(ilvbl)

CUD:	121525719(ilvbl)

ALAT:

119010368(ilvbl)

MZE:	101463789(ilvbl)

ONL:	100709955(ilvbl)

OAU:	116323296(ilvbl)

OLA:	101163679(ilvbl)

OML:	112149908(ilvbl)

CSAI:

133441586(ilvbl)

XMA:	102234807(ilvbl)

XCO:	114162024(ilvbl)

XHE:	116737480(ilvbl)

PRET:

103474769(ilvbl)

PFOR:

103145360(ilvbl)

PLAI:

106957097(ilvbl)

PMEI:

106934179(ilvbl)

GAF:	122832340(ilvbl)

PPRL:

129359339(ilvbl)

CVG:	107083444(ilvbl)

CTUL:

119771777(ilvbl)

GMU:	124884261(ilvbl)

NFU:	107380712(ilvbl)

KMR:	108238114(ilvbl)

ALIM:

106525655(ilvbl)

NWH:	119410847(ilvbl)

AOCE:

111569176(ilvbl)

MCEP:

125014109(ilvbl)

CSEM:

103377671(ilvbl)

POV:	109634652(ilvbl)

SSEN:

122773732(ilvbl)

HHIP:

117772321(ilvbl)

HSP:	118106484(ilvbl)

SMAU:

118298905(ilvbl)

LCF:

108898847

SDU:	111233424(ilvbl)

SLAL:

111665431(ilvbl)

XGL:	120792286(ilvbl)

HCQ:	109512870(ilvbl)

SSCV:

125972163

SBIA:

133505199(ilvbl)

PEE:	133405067(ilvbl)

PTAO:

133481939(ilvbl)

BPEC:

110162007(ilvbl)

MALB:

109960338(ilvbl)

BSPL:

129602891(ilvbl)

SJO:	128360550(ilvbl)

SASA:

100195000(ilvbl) 106612961

STRU:

115163550 115206453

OTW:	112265620 112267193

OMY:	110504042 110507865

OGO:	124005820(ilvbl)

ONE:	115136657 115141916(ilvbl)

OKI:	109905803 109909213

OKE:	118396764 118397529

SALP:

111949580 111960698

SNH:	120018133 120028754

CCLU:

121558375 121567765

ELS:	105023814(ilvbl)

SFM:	108932453(ilvbl)

PKI:	111849920(ilvbl)

AANG:

118236513(ilvbl)

LOC:	102689356(ilvbl)

PSPA:

121309519(ilvbl)

ARUT:

117397081 117397298

PSEX:

120535913(ilvbl)

LCM:	102358843(ILVBL)

CMK:	103180240(ilvbl)

RTP:	109924171(ilvbl)

CPLA:

122540740(ilvbl)

HOC:	132829615(ilvbl)

LERI:

129712439(ilvbl)

PMRN:

116948090(ILVBL)

LRJ:	133342010(ILVBL)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

AJC:

SKO:	100369292(ILVBL)

RZE:

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

IEL:

DPX:	DAPPUDRAFT_303446

DMK:

DPZ:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:	107367223 107369168

DPTE:

DFR:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

CEL:	CELE_T26C12.1(T26C12.1)

CBR:

CBG_03380

CRQ:	GCK72_014340

NAI:	NECAME_13160

BMY:	BM_BM6026(Bm6026)

LOA:	LOAG_18311

TSP:

Tsp_05321

HRO:	HELRODRAFT_185752

LGI:	LOTGIDRAFT_214325

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CVN:

CANU:

OED:

MYI:

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

OBI:

OSN:

LAK:

SMM:	Smp_005390.1

SHX:	MS3_00002319

OVI:	T265_08071

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

TAD:	TRIADDRAFT_51690

AQU:

100640012

DDI:	DDB_G0278053(ilvB)

DPP:	DICPUDRAFT_51993

DFA:	DFA_03065(ilvB)

» show all

Reference

PMID:8954801

Authors

Joutel A, Ducros A, Alamowitch S, Cruaud C, Domenga V, Marechal E, Vahedi K, Chabriat H, Bousser MG, Tournier-Lasserve E

Title

A human homolog of bacterial acetolactate synthase genes maps within the CADASIL critical region.

Journal

Genomics 38:192-8 (1996)
DOI:10.1006/geno.1996.0615

Sequence

[hsa:10994]

Reference

PMID:28289220

Authors

Kitamura T, Seki N, Kihara A

Title

Phytosphingosine degradation pathway includes fatty acid alpha-oxidation reactions in the endoplasmic reticulum.

Journal

Proc Natl Acad Sci U S A 114:E2616-E2623 (2017)
DOI:10.1073/pnas.1700138114

Sequence

[hsa:10994]

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