ORTHOLOGY: K11417
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Entry
K11417 KO
Symbol
SIRT7, SIR2L7
Name
NAD-dependent protein deacetylase sirtuin 7 [EC:
2.3.1.286
]
Pathway
map00760
Nicotinate and nicotinamide metabolism
map01100
Metabolic pathways
Reaction
R10633
R10634
Brite
KEGG Orthology (KO) [BR:
ko00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
K11417 SIRT7, SIR2L7; NAD-dependent protein deacetylase sirtuin 7
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins
K11417 SIRT7, SIR2L7; NAD-dependent protein deacetylase sirtuin 7
Enzymes [BR:
ko01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.286 protein acetyllysine N-acetyltransferase
K11417 SIRT7, SIR2L7; NAD-dependent protein deacetylase sirtuin 7
Chromosome and associated proteins [BR:
ko03036
]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
SIRTs (sirtuins, class III HDACs)
K11417 SIRT7, SIR2L7; NAD-dependent protein deacetylase sirtuin 7
BRITE hierarchy
Other DBs
GO:
0034979
Genes
HSA:
51547
(SIRT7)
PTR:
454975
(SIRT7)
PPS:
100981638
(SIRT7)
GGO:
101144438
(SIRT7)
PON:
100454765
(SIRT7)
PPYG:
129018227
(SIRT7)
NLE:
100593210
(SIRT7)
HMH:
116483751
(SIRT7)
SSYN:
129462353
(SIRT7)
MCC:
715069
(SIRT7)
MCF:
102141105
(SIRT7)
MTHB:
126939107
MNI:
105469317
(SIRT7)
CSAB:
103243740
(SIRT7)
CATY:
105588585
(SIRT7)
PANU:
101008717
(SIRT7)
TGE:
112609419
(SIRT7)
MLEU:
105531180
(SIRT7)
RRO:
104654972
(SIRT7)
RBB:
108534099
(SIRT7)
TFN:
117066349
(SIRT7)
PTEH:
111542285
(SIRT7)
CANG:
105526842
(SIRT7)
CJC:
100399307
(SIRT7)
SBQ:
101046747
(SIRT7)
CIMI:
108301649
(SIRT7)
ANAN:
105717469
(SIRT7)
CSYR:
103262780
(SIRT7)
MMUR:
105884945
(SIRT7)
LCAT:
123650710
(SIRT7)
PCOQ:
105820027
(SIRT7)
OGA:
100950181
(SIRT7)
MMU:
209011
(Sirt7)
MCAL:
110305783
(Sirt7)
MPAH:
110331620
(Sirt7)
RNO:
303745
(Sirt7)
MCOC:
116077319
(Sirt7)
ANU:
117710076
(Sirt7)
MUN:
110548838
(Sirt7)
CGE:
100757186
(Sirt7)
MAUA:
101837321
(Sirt7)
PROB:
127220350
(Sirt7)
PLEU:
114680631
(Sirt7)
MORG:
121444109
121444626
MFOT:
126500368
AAMP:
119813375
(Sirt7)
NGI:
103730192
(Sirt7)
HGL:
101716210
(Sirt7)
CPOC:
100714091
(Sirt7)
CCAN:
109702732
(Sirt7)
DSP:
122099412
(Sirt7)
PLOP:
125365243
(Sirt7)
NCAR:
124980825
OPI:
101530952
TUP:
102495546
(SIRT7)
GVR:
103593329
(SIRT7)
CFA:
483371
(SIRT7)
CLUD:
112672947
(SIRT7)
VVP:
112920905
(SIRT7)
VLG:
121473139
(SIRT7)
NPO:
129515706
(SIRT7)
AML:
100470238
(SIRT7)
UMR:
103666002
(SIRT7)
UAH:
113244493
(SIRT7)
UAR:
123777893
(SIRT7)
ELK:
111160398
LLV:
125088148
MPUF:
101689105
(SIRT7)
MNP:
132004014
(SIRT7)
MLK:
131816831
(SIRT7)
NVS:
122905879
(SIRT7)
ORO:
101376632
(SIRT7)
EJU:
114216077
(SIRT7)
ZCA:
113908208
(SIRT7)
MLX:
118024158
(SIRT7)
NSU:
110572467
(SIRT7)
LWW:
102740416
(SIRT7)
FCA:
101100681
(SIRT7)
PYU:
121018077
(SIRT7)
PCOO:
112864548
(SIRT7)
PBG:
122485961
(SIRT7)
PVIV:
125151596
(SIRT7)
LRUF:
124522594
PTG:
102972924
(SIRT7)
PPAD:
109276764
(SIRT7)
PUC:
125926238
AJU:
106986346
HHV:
120228130
(SIRT7)
BTA:
505662
(SIRT7)
BOM:
102287843
(SIRT7)
BIU:
109573911
(SIRT7)
BBUB:
102404018
(SIRT7)
BBIS:
105000590
(SIRT7)
CHX:
102168297
(SIRT7)
OAS:
101108066
(SIRT7)
BTAX:
128065011
(SIRT7)
ODA:
120866871
(SIRT7)
CCAD:
122438582
(SIRT7)
MBEZ:
129544596
(SIRT7)
SSC:
100125965
(SIRT7)
CFR:
102507714
(SIRT7)
CBAI:
105065548
(SIRT7)
CDK:
105106386
(SIRT7)
VPC:
102544294
(SIRT7)
BACU:
103018701
(SIRT7)
BMUS:
118886389
(SIRT7)
LVE:
103081341
(SIRT7)
OOR:
101276270
(SIRT7)
DLE:
111182686
(SIRT7)
PCAD:
102983232
(SIRT7)
PSIU:
116745216
(SIRT7)
NASI:
112410452
(SIRT7)
ECB:
100054966
(SIRT7)
EPZ:
103551120
(SIRT7)
EAI:
106845950
(SIRT7)
MYB:
102248315
(SIRT7)
MYD:
102759133
(SIRT7)
MMYO:
118671275
(SIRT7)
MLF:
102430937
(SIRT7)
MDT:
132219222
(SIRT7)
PKL:
118704524
(SIRT7)
EFUS:
103298345
(SIRT7)
MNA:
107539061
(SIRT7)
DRO:
112298721
(SIRT7)
SHON:
119002722
(SIRT7)
AJM:
119058536
(SIRT7)
PDIC:
114502863
(SIRT7)
PHAS:
123817724
(SIRT7)
MMF:
118633854
(SIRT7)
PPAM:
129086637
(SIRT7)
HAI:
109393057
(SIRT7)
RFQ:
117013774
(SIRT7)
PALE:
102888412
(SIRT7)
PGIG:
120600386
(SIRT7)
RAY:
107520265
(SIRT7)
MJV:
108395248
(SIRT7)
TOD:
119231666
(SIRT7)
SARA:
101552422
(SIRT7)
SETR:
126013472
(SIRT7)
LAV:
100675031
(SIRT7)
TMU:
101341220
ETF:
101661952
(SIRT7)
DNM:
101434803
(SIRT7)
MDO:
100030060
(SIRT7)
GAS:
123243711
(SIRT7)
SHR:
100925189
(SIRT7)
AFZ:
127560624
PCW:
110218300
(SIRT7)
TVP:
118848682
(SIRT7)
OAA:
103167172
(SIRT7)
GGA:
103214197
(SIRT7)
PCOC:
116232566
(SIRT7)
MGP:
100545598
(SIRT7)
CJO:
107322164
(SIRT7)
TPAI:
128083058
(SIRT7)
LMUT:
125702169
(SIRT7)
NMEL:
110407495
(SIRT7)
APLA:
101800216
(SIRT7)
ACYG:
106046758
(SIRT7)
CATA:
118259235
(SIRT7)
AFUL:
116496403
(SIRT7)
TGU:
100228792
(SIRT7)
LSR:
110472465
(SIRT7)
SCAN:
103819914
(SIRT7)
PMOA:
120505492
(SIRT7)
OTC:
121338509
(SIRT7)
PRUF:
121352779
(SIRT7)
GFR:
102032305
(SIRT7)
FAB:
101820436
(SIRT7)
OMA:
130260416
(SIRT7)
PHI:
102099591
(SIRT7)
PMAJ:
107212419
(SIRT7)
CCAE:
111937593
(SIRT7)
CCW:
104698225
(SIRT7)
CBRC:
103613445
(SIRT7)
ETL:
114060345
(SIRT7)
ZAB:
102072159
(SIRT7)
ZLE:
135455285
(SIRT7)
ACHL:
103800052
(SIRT7)
SVG:
106859892
(SIRT7)
MMEA:
130581997
(SIRT7)
SATI:
136369384
(SIRT7)
FPG:
101915536
(SIRT7)
CCRI:
104155064
(SIRT7)
NNT:
104407689
(SIRT7)
SHAB:
115616588
(SIRT7)
ACUN:
113486984
(SIRT7)
TALA:
104366341
(SIRT7)
ACHC:
115342314
(SIRT7)
HALD:
104310483
(SIRT7)
HLE:
104832140
(SIRT7)
AGEN:
126043686
GCL:
127023989
CSTI:
104560847
(SIRT7)
LDI:
104349967
(SIRT7)
DPUB:
104297988
(SIRT7)
BRHI:
104499413
(SIRT7)
EGZ:
104131205
(SIRT7)
NNI:
104014384
(SIRT7)
PCRI:
104023707
(SIRT7)
PCAO:
104044887
(SIRT7)
PADL:
103917462
(SIRT7)
AFOR:
103899061
(SIRT7)
FGA:
104083956
(SIRT7)
GSTE:
104262920
(SIRT7)
PGUU:
104469174
(SIRT7)
PLET:
104613923
(SIRT7)
EHS:
104516863
(SIRT7)
CMAC:
104478828
(SIRT7)
TEO:
104375073
(SIRT7)
BREG:
104644093
(SIRT7)
ACAR:
104524525
(SIRT7)
CPEA:
104398567
(SIRT7)
CVF:
104283134
(SIRT7)
RTD:
128917890
(SIRT7)
AAM:
106487099
(SIRT7)
AROW:
112974796
(SIRT7)
NPD:
112945353
(SIRT7)
TGT:
104564887
(SIRT7)
DNE:
112990971
(SIRT7)
SCAM:
104140213
(SIRT7)
ASN:
102382706
(SIRT7)
AMJ:
102562811
(SIRT7)
PSS:
102456117
(SIRT7)
CMY:
102937509
(SIRT7)
CCAY:
125621039
(SIRT7)
DCC:
119842792
(SIRT7)
CPIC:
101937028
(SIRT7)
TST:
117887337
(SIRT7)
ACS:
100552312
(sirt7)
ASAO:
132768704
(SIRT7)
PVT:
110090620
(SIRT7)
SUND:
121923906
(SIRT7)
PBI:
103063418
(SIRT7)
PMUR:
107294411
(SIRT7)
CTIG:
120308468
(SIRT7)
TSR:
106555160
(SIRT7)
PGUT:
117663047
(SIRT7)
APRI:
131193660
(SIRT7)
PTEX:
113437071
(SIRT7)
NSS:
113412000
(SIRT7)
VKO:
123018117
(SIRT7)
PMUA:
114589553
(SIRT7)
PRAF:
128407392
(SIRT7)
ZVI:
118079751
(SIRT7)
HCG:
128342109
(SIRT7)
GJA:
107118137
(SIRT7)
STOW:
125429258
(SIRT7)
EMC:
129328313
(SIRT7)
XLA:
495235
(sirt7.L)
XTR:
548532
(sirt7)
NPR:
108784742
(SIRT7)
RTEM:
120918918
(SIRT7)
BBUF:
121003235
(SIRT7)
BGAR:
122940013
(SIRT7)
MUO:
115471548
(SIRT7)
GSH:
117368010
DRE:
796135
(sirt7)
SRX:
107705833
107706268
SANH:
107667823
SGH:
107569249
CCAR:
109051822
109075999
(sirt7)
CAUA:
113039710
(sirt7)
CGIB:
127988558
PTET:
122327648
(sirt7)
LROH:
127153563
(sirt7)
OMC:
131530306
(sirt7)
PPRM:
120468732
(sirt7)
RKG:
130075380
(sirt7)
MAMB:
125258944
(sirt7)
CIDE:
127520577
CERY:
137027577
(sirt7)
MASI:
127438274
127438911
TROS:
130548672
(sirt7)
MANU:
129454068
(sirt7)
IPU:
108270905
IFU:
128613288
(sirt7)
PHYP:
113536446
(sirt7)
SMEO:
124390775
(sirt7)
TFD:
113646664
(sirt7)
TVC:
132848497
(sirt7)
TRN:
134331388
(sirt7)
AMEX:
103035964
(sirt7)
CMAO:
118818617
(sirt7)
EEE:
113577770
(sirt7)
CHAR:
105901581
(sirt7)
TRU:
101061516
(sirt7)
TFS:
130527690
(sirt7)
TNG:
GSTEN00026253G001
LCO:
104930255
(sirt7)
NCC:
104950018
(sirt7)
TBEN:
117474477
(sirt7)
CGOB:
115015548
(sirt7)
PGEO:
117459573
(sirt7)
GACU:
117561578
(sirt7)
EMAC:
134864173
(sirt7)
ELY:
117255526
(sirt7)
EFO:
125885905
(sirt7)
PLEP:
121942163
(sirt7)
SLUC:
116042646
(sirt7)
ECRA:
117959172
(sirt7)
ESP:
116695962
(sirt7)
PFLV:
114571920
(sirt7)
GAT:
120824797
(sirt7)
PPUG:
119218356
(sirt7)
AFB:
129096454
(sirt7)
CLUM:
117731454
(sirt7)
PSWI:
130190135
(sirt7)
MSAM:
119899536
(sirt7)
SCHU:
122873960
(sirt7)
CUD:
121507885
(sirt7)
ALAT:
119005479
(sirt7)
ASTR:
137600204
(sirt7)
MZE:
101486918
(sirt7)
ONL:
100700228
(sirt7)
OAU:
116330386
(sirt7)
OLA:
101156229
(sirt7)
OML:
112137386
(sirt7)
CSAI:
133452854
(sirt7)
XMA:
102222882
(sirt7)
XCO:
114144477
(sirt7)
XHE:
116720757
(sirt7)
PFOR:
103150514
(sirt7)
PLAI:
106951276
(sirt7)
PMEI:
106917551
(sirt7)
PPRL:
129366982
(sirt7)
CVG:
107090740
(sirt7)
CTUL:
119783271
(sirt7)
GMU:
124868411
(sirt7)
NFU:
107392242
(sirt7)
KMR:
108236305
(sirt7)
ALIM:
106521455
(sirt7)
NWH:
119422822
(sirt7)
AOCE:
111581956
(sirt7)
MCEP:
125004292
(sirt7)
CSEM:
103383954
(sirt7)
POV:
109627220
(sirt7)
SSEN:
122771219
(sirt7)
HHIP:
117768937
(sirt7)
HSP:
118100413
(sirt7)
PPLT:
128437531
(sirt7)
SMAU:
118312601
(sirt7)
LCF:
108875649
SDU:
111229259
(sirt7)
SLAL:
111666696
(sirt7)
XGL:
120799810
(sirt7)
HCQ:
109527332
(sirt7)
SSCV:
125968615
SBIA:
133506372
(sirt7)
PEE:
133403845
(sirt7)
PTAO:
133476466
(sirt7)
BPEC:
110165217
(sirt7)
MALB:
109958021
(sirt7)
BSPL:
114865557
(sirt7)
SJO:
128370487
(sirt7)
SASA:
106571917
106591833
STRU:
115147564
115181665
OTW:
112241081
(sirt7)
OMY:
110485494
110487229
OGO:
124019153
ONE:
115126853
(sirt7)
OKI:
109876256
(sirt7)
OKE:
118382249
(sirt7)
SALP:
112077059
(sirt7)
SNH:
120018914
120018925
CCLU:
121534300
(sirt7)
ELS:
105012033
(sirt7)
SFM:
108930195
(sirt7)
PKI:
111846584
(sirt7)
AANG:
118217796
(sirt7)
LOC:
102687441
(sirt7)
PSPA:
121296275
121307653
(sirt7)
ARUT:
117422946
PSEX:
120517205
(sirt7)
LCM:
102361134
(SIRT7)
CMK:
103175524
(sirt7)
RTP:
109913423
(sirt7)
CPLA:
122562190
(sirt7)
HOC:
132827783
(sirt7)
LERI:
129708275
(sirt7)
PMRN:
116949674
(SIRT7)
LRJ:
133345690
(SIRT7)
BFO:
118428862
BBEL:
109463311
CIN:
100185848
SCLV:
120338471
SPU:
115923816
762797
LPIC:
129269346
129269355
APLC:
110979698
ARUN:
117292762
AJC:
117109715
SKO:
102807294
DME:
Dmel_CG11305
(Sirt7)
DER:
6555088
DSE:
6612647
DSI:
Dsimw501_GD21410
(Dsim_GD21410)
DYA:
Dyak_GE23831
DAN:
6499072
DSR:
110177294
DPO:
4801594
DPE:
6587470
DMN:
108156312
DWI:
6649799
DGR:
6564287
DMO:
Dmoj_GI24191
DAZ:
108612526
DNV:
108656178
DHE:
111596249
DVI:
6632950
RZE:
108364590
TDA:
119677396
LCQ:
111675428
ECOE:
129939922
CLON:
129607978
AAG:
5568215
AALB:
109422744
109431874
ASUA:
134224752
CQU:
CpipJ_CPIJ006726
CPII:
120412919
CNS:
116340850
BCOO:
119075873
AME:
413728
ACER:
107994553
ALAB:
122713600
ADR:
102674336
AFLR:
100865090
BIM:
100748089
BBIF:
117212461
BVK:
117231299
BVAN:
117156530
BTER:
100644651
BAFF:
126917545
BPYO:
122573087
BPAS:
132907347
FVI:
122533853
CCAL:
108629379
OBB:
114872635
OLG:
117607554
MGEN:
117226495
NMEA:
116433033
CGIG:
122401280
SOC:
105194499
MPHA:
105837803
AEC:
105143198
ACEP:
105617738
PBAR:
105429217
VEM:
105565592
HST:
105182961
DQU:
106743219
CFO:
105249518
FEX:
115237002
LHU:
105671380
(Sirt7)
PGC:
109855832
OBO:
105287022
PCF:
106787131
PFUC:
122521961
VPS:
122627276
VCRB:
124432048
VVE:
124946809
NVI:
100120550
CSOL:
105368976
TPRE:
106649778
LHT:
122509465
LBD:
127280890
MDL:
103580731
CGLO:
123259536
FAS:
105272640
DAM:
107045753
AGIF:
122852693
CINS:
118065226
VCAN:
122413911
CCIN:
107264668
DSM:
124404832
NPT:
124212334
NFB:
124176190
NLO:
107218142
NVG:
124297322
AROA:
105693278
TCA:
658898
DPA:
109539366
SOY:
115887531
AGRG:
126739907
ATD:
109607907
CSET:
123322795
AGB:
108907428
LDC:
111508162
DVV:
114342974
NVL:
108561596
APLN:
108743379
PPYR:
116173617
OTU:
111422265
BMOR:
101745061
BMAN:
114244672
MSEX:
115451926
DPL:
KGM_209390
BANY:
112051463
MJU:
123871962
NIQ:
126770987
VCD:
124529990
MCIX:
123657505
PMAC:
106721364
PXU:
106118804
PRAP:
111002369
PBX:
123711708
PNAP:
125057816
ZCE:
119832402
LSIN:
126969622
AAGE:
121732404
HAW:
110381469
HZE:
124633341
TNL:
113508084
SLIU:
111362573
OFU:
114357336
ATRA:
106133136
GMW:
113519217
PGW:
126368874
CCRN:
123294833
API:
100165290
DNX:
107165534
AGS:
114124930
RMD:
113558457
ACOO:
126834232
DVT:
126905825
BTAB:
109043606
CLEC:
106664597
HHAL:
106679937
(Sirt7)
NLU:
111058155
HVI:
124354050
MQU:
129000784
PHU:
Phum_PHUM430270
FOC:
113206009
ZNE:
110837609
CSEC:
111868291
BROR:
134531952
IEL:
124172060
FCD:
110855031
PVM:
113823577
EAF:
111699595
LSM:
121113547
TCF:
131882531
PPOI:
119095195
DSV:
119453160
119454022
RSAN:
119399991
RMP:
119180137
DPTE:
113796377
DFR:
124497546
CSCU:
111630726
CVS:
136970600
(Sirt7)
PTEP:
107452595
ABRU:
129984111
UDV:
129225894
SDM:
118204977
LPOL:
106466292
PMEO:
129598012
BMY:
BM_BM4160
(Bma-sir-2.4.1)
LOA:
LOAG_08259
HRO:
HELRODRAFT_115195
LGI:
LOTGIDRAFT_196160
PVUL:
126810801
BGT:
106067692
GAE:
121379855
HRF:
124131524
HRJ:
124281070
CRG:
105335756
CANU:
128166129
CVN:
111121317
111121410
OED:
125670769
MYI:
110447655
PMAX:
117322123
OBI:
106871322
OSN:
115215796
LJP:
135470110
LAK:
106154544
OVI:
T265_15604
NVE:
5500391
5506400
EPA:
110238242
ATEN:
116292678
ADF:
107331839
AMIL:
114947528
PDAM:
113685530
SPIS:
111334642
DGT:
114539488
114541709
114544100
XEN:
124448473
RES:
135687327
TAD:
TRIADDRAFT_53549
BPG:
Bathy12g02720
MIS:
MICPUN_70072
NCR:
NCU07624
(nst-7)
NTE:
NEUTE1DRAFT77995
(NEUTE1DRAFT_77995)
SMP:
10805392
(SMAC4_07316)
PPSD:
QC762_001430
PPSP:
QC763_001430
PPSA:
QC764_001430
FFC:
NCS54_01348000
FKR:
NCS57_01337100
FMU:
J7337_013331
PCHM:
VFPPC_00606
CLUP:
CLUP02_11781
CHIG:
CH63R_11290
CDET:
87946042
(CDEST_09539)
MBR:
MONBRDRAFT_28831
SRE:
PTSG_08005
ACAN:
ACA1_076810
EHX:
EMIHUDRAFT_449256
EMIHUDRAFT_455283
EMIHUDRAFT_460044
EMIHUDRAFT_460268
NGR:
NAEGRDRAFT_62017
NAEGRDRAFT_67056
» show all
Taxonomy
UniProt
Reference
PMID:
16618798
Authors
Ford E, Voit R, Liszt G, Magin C, Grummt I, Guarente L
Title
Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription.
Journal
Genes Dev 20:1075-80 (2006)
DOI:
10.1101/gad.1399706
Sequence
[hsa:
51547
] [mmu:
209011
]
LinkDB
All DBs
DBGET
integrated database retrieval system