KEGG ORTHOLOGY: K11463

ORTHOLOGY: K11463

Entry

K11463                      KO

Symbol

SUZ12

Name

polycomb protein SUZ12

Pathway

map03083

Polycomb repressive complex

Disease

H02522

Imagawa-Matsumoto syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09126 Chromosome
   03083 Polycomb repressive complex
    K11463  SUZ12; polycomb protein SUZ12
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K11463  SUZ12; polycomb protein SUZ12
Chromosome and associated proteins [BR:ko03036]
Eukaryotic type
  Histone modification proteins
   Polycomb repressive complex (PRC) and associated proteins
    PRC2.1
     K11463  SUZ12; polycomb protein SUZ12
    PRC2.2
     K11463  SUZ12; polycomb protein SUZ12

Genes

HSA:	23512(SUZ12)

PTR:	468384 748393(SUZ12)

PPS:	103785028(SUZ12)

GGO:	101149019(SUZ12)

PON:	100460330(SUZ12) 103889600

NLE:	100607575 115831487(SUZ12)

HMH:	116474540(SUZ12)

MCC:	717834(SUZ12)

MCF:	102114791(SUZ12)

MTHB:

126938979

MNI:	105485200(SUZ12)

CSAB:

103242683(SUZ12)

CATY:

105589404(SUZ12)

PANU:

101024182(SUZ12)

TGE:	112609160(SUZ12)

MLEU:

105548882(SUZ12)

RRO:	104669869(SUZ12)

RBB:	108541394(SUZ12)

TFN:	117067560(SUZ12)

PTEH:

111520272(SUZ12)

CANG:

105508765(SUZ12)

CJC:	100391943(SUZ12)

SBQ:	101035798(SUZ12)

CIMI:

108313621(SUZ12)

CSYR:

103255507(SUZ12)

MMUR:

105856652(SUZ12)

LCAT:

123620309(SUZ12)

PCOQ:

105813582(SUZ12)

OGA:	100961562(SUZ12)

MMU:	52615(Suz12)

MCAL:

110305511(Suz12)

MPAH:

110331496(Suz12)

RNO:	688041(Suz12)

MCOC:

116077232(Suz12)

ANU:	117710674(Suz12)

MUN:	110545100(Suz12)

CGE:	100771055(Suz12)

MAUA:

101826279(Suz12)

PROB:

127218813(Suz12)

PLEU:

114691533(Suz12)

MORG:

121456705(Suz12)

MFOT:

126492339

AAMP:

119812928(Suz12)

NGI:	103724513(Suz12)

HGL:	101720893(Suz12)

CPOC:

100720614(Suz12)

CCAN:

109693264(Suz12)

DORD:

105985656(Suz12)

DSP:	122117966(Suz12)

PLOP:

125366562(Suz12)

NCAR:

124979869

MMMA:

107155155(Suz12)

OCU:

100350588

OPI:	101533124(SUZ12)

TUP:	102498645(SUZ12)

GVR:	103601869(SUZ12)

CFA:	491158(SUZ12)

CLUD:

112677704(SUZ12)

VVP:	112933114(SUZ12)

VLG:	121473721(SUZ12)

NPO:	129513892(SUZ12)

AML:	100483654(SUZ12)

UMR:	103667426(SUZ12)

UAH:	113268999(SUZ12)

UAR:	123776857(SUZ12)

ELK:

111151219

LLV:

125087616

MPUF:

101686756 101691379(SUZ12)

MNP:	132003231 132009337

MLK:	131816069(SUZ12) 131820999

NVS:	122906440(SUZ12)

ORO:	101377304(SUZ12)

EJU:	114213807(SUZ12)

ZCA:	113907918(SUZ12)

MLX:	118025317(SUZ12)

NSU:	110593323(SUZ12)

LWW:	102746695(SUZ12)

FCA:	101093155(SUZ12)

PYU:	121017159(SUZ12)

PCOO:

112852751(SUZ12)

PBG:	122485200(SUZ12)

PVIV:

125151165(SUZ12)

LRUF:

124513055

PTG:	102971070(SUZ12)

PPAD:

109251896(SUZ12)

PUC:

125927476

AJU:

106985253

HHV:	120246131(SUZ12)

BTA:	538774(SUZ12)

BOM:	102286864(SUZ12)

BIU:	109574076(SUZ12)

BBUB:

102390770(SUZ12)

BBIS:

105004167(SUZ12)

CHX:	102179978(SUZ12)

OAS:	101116666(SUZ12)

BTAX:

128065240(SUZ12)

ODA:	120866331(SUZ12)

CCAD:

122448839(SUZ12)

MBEZ:

129536405(SUZ12)

SSC:	100294712(SUZ12)

CFR:	102514908(SUZ12)

CBAI:

105071641(SUZ12)

CDK:	105088255(SUZ12)

VPC:	102525214(SUZ12)

BACU:

103007024(SUZ12)

BMUS:

118886351(SUZ12)

LVE:	103070823(SUZ12)

OOR:	101284063(SUZ12)

DLE:	111185878(SUZ12)

PCAD:

102996173(SUZ12)

PSIU:

116746039(SUZ12)

NASI:

112394189(SUZ12)

ECB:	100071831(SUZ12)

EPZ:	103551813(SUZ12)

EAI:	106844614(SUZ12)

MYB:	102239541(SUZ12)

MYD:	102753876(SUZ12)

MMYO:

118671781(SUZ12)

MLF:	102437331(SUZ12)

PKL:	118728037(SUZ12)

EFUS:

103291691(SUZ12)

MNA:	107533052(SUZ12)

DRO:	112308534(SUZ12)

SHON:

119003452(SUZ12)

AJM:	119050471(SUZ12)

PDIC:

114502536(SUZ12)

PHAS:

123817382(SUZ12)

MMF:	118634189(SUZ12)

PPAM:

129070269(SUZ12)

HAI:	109385163(SUZ12)

RFQ:	117013185(SUZ12)

PALE:

102898554(SUZ12)

PGIG:

120620927(SUZ12)

PVP:	105291948(SUZ12)

RAY:	107514629(SUZ12)

MJV:	108399595(SUZ12)

TOD:	119230486(SUZ12)

SARA:

101539680(SUZ12)

SETR:

126006189(SUZ12)

LAV:	100665241(SUZ12)

TMU:

101342783

ETF:	101659316(SUZ12)

DNM:	101445279(SUZ12)

MDO:	100018909(SUZ12)

GAS:	123246787(SUZ12)

SHR:	100922832(SUZ12)

AFZ:

127558963

PCW:	110192229(SUZ12)

OAA:	100080410(SUZ12)

GGA:	417406(SUZ12)

PCOC:

116232430(SUZ12)

MGP:	100547545(SUZ12)

CJO:	107322029(SUZ12)

TPAI:

128083283(SUZ12)

LMUT:

125702216(SUZ12)

NMEL:

110407216(SUZ12)

APLA:

101798973(SUZ12)

ACYG:

106034608(SUZ12)

CATA:

118253957(SUZ12)

AFUL:

116496401(SUZ12)

TGU:	100228788(SUZ12)

LSR:	110474384(SUZ12)

SCAN:

103819793(SUZ12)

PMOA:

120505604(SUZ12)

OTC:	121338399(SUZ12)

PRUF:

121363456(SUZ12)

GFR:	102041471(SUZ12)

FAB:	101816083(SUZ12)

OMA:	130260410(SUZ12)

PHI:	102105937(SUZ12)

PMAJ:

107212472(SUZ12)

CCAE:

111937565(SUZ12)

CCW:	104694256(SUZ12)

CBRC:

103619080(SUZ12)

ETL:	114056848(SUZ12)

ZAB:	102071071(SUZ12)

ACHL:

103807847(SUZ12)

SVG:	106854284(SUZ12)

MMEA:

130575139(SUZ12)

HRT:	120761000(SUZ12)

FPG:	101922638(SUZ12)

FCH:	102056327(SUZ12)

CLV:	102086519(SUZ12)

EGZ:	104123731(SUZ12)

NNI:	104014310(SUZ12)

PCRI:

104034887(SUZ12)

PLET:

104621270(SUZ12)

EHS:	104512898(SUZ12)

PCAO:

104039426(SUZ12)

ACUN:

113486880(SUZ12)

TALA:

104355929(SUZ12)

PADL:

103916663(SUZ12)

AFOR:

103905886(SUZ12)

ACHC:

115341528(SUZ12)

HALD:

104317270(SUZ12)

HLE:	104838739(SUZ12)

AGEN:

126043404

GCL:

127023925

CCRI:

104158451(SUZ12)

CSTI:

104559436(SUZ12)

CMAC:

104487674(SUZ12)

MUI:	104548067(SUZ12)

BREG:

104640426(SUZ12)

FGA:	104077920(SUZ12)

LDI:	104351224(SUZ12)

MNB:	103768616(SUZ12)

OHA:	104332961(SUZ12)

NNT:	104409175(SUZ12)

SHAB:

115616645(SUZ12)

DPUB:

104310091(SUZ12)

PGUU:

104458714(SUZ12)

ACAR:

104518020

CPEA:

104393297(SUZ12)

AVIT:

104275662(SUZ12)

CVF:	104282156(SUZ12)

RTD:	128918041(SUZ12)

CUCA:

104061990(SUZ12)

TEO:	104384541(SUZ12)

BRHI:

104499453(SUZ12)

AAM:	106493125(SUZ12)

AROW:

112966892(SUZ12)

NPD:	112953772(SUZ12)

TGT:	104571324(SUZ12)

DNE:	112982486(SUZ12)

SCAM:

104146745(SUZ12)

ASN:	102369014(SUZ12)

AMJ:	102573751(SUZ12)

CPOO:

109314988(SUZ12)

GGN:	109297308(SUZ12)

PSS:	102462113(SUZ12)

CMY:	102947209(SUZ12)

CCAY:

125621878(SUZ12)

DCC:	119842913(SUZ12)

CPIC:

101944946(SUZ12)

TST:	117887728(SUZ12)

CABI:

116839590(SUZ12)

MRV:	120383363(SUZ12)

ACS:	100559797(suz12)

ASAO:

132768252(SUZ12)

PVT:	110073942(SUZ12)

SUND:

121923315(SUZ12)

PBI:	103063790(SUZ12)

PMUR:

107292197(SUZ12)

CTIG:

120308096(SUZ12)

TSR:	106548898(SUZ12)

PGUT:

117662841(SUZ12)

APRI:

131191464(SUZ12)

PTEX:

113443122(SUZ12)

NSS:	113420729(SUZ12)

VKO:	123019293(SUZ12)

PMUA:

114587371(SUZ12)

PRAF:

128407155(SUZ12)

ZVI:	118079573(SUZ12)

HCG:	128346007(SUZ12)

GJA:	107121718(SUZ12)

STOW:

125428030(SUZ12)

EMC:	129346252(SUZ12)

XLA:	100329217(suz12) 108701224(suz12.L)

XTR:	779745(suz12)

NPR:	108802983(SUZ12)

RTEM:

120919332(SUZ12)

BBUF:

121005544(SUZ12)

BGAR:

122922447(SUZ12)

MUO:	115473441(SUZ12)

GSH:	117367830(SUZ12)

DRE:	561871(suz12b) 794171(suz12a)

SRX:	107710018 107710288(suz12) 107719980 107721513

SANH:

107654477 107669539 107688101 107698691(suz12)

SGH:	107553303 107590398 107591916 107601261

CCAR:

109058280 109081966 109084002 109092321

CAUA:

113047251 113047331 113050694 113081122 113098215

CGIB:

127951040 127952890 127960042 128015487

PTET:

122339269(suz12a) 122346825(suz12b)

LROH:

127163196(suz12a) 127166528(suz12b)

OMC:	131535996(suz12a) 131541968(suz12b)

PPRM:

120471219(suz12b) 120489211(suz12a)

RKG:	130075841(suz12a) 130081201(suz12b)

MAMB:

125271446(suz12a) 125272921(suz12b)

CIDE:

127508483 127514888

MASI:

127446235 127449003 127450166 127451323

TROS:

130561381(suz12a)

TDW:	130425825(suz12a)

MANU:

129434126(suz12a)

IPU:	108273272(suz12b) 108278724(suz12a)

IFU:	128615805(suz12b) 128622181(suz12a)

PHYP:

113523680 113528585

SMEO:

124389203(suz12b) 124396536(suz12a)

TFD:	113656880(suz12b) 113659252(suz12a)

TVC:	132845049(suz12b) 132861430(suz12a)

AMEX:

103037652(suz12) 103046942

CMAO:

118808606(suz12b) 118821017(suz12a)

EEE:	113578849(suz12) 113582195

CHAR:

105892302(suz12b) 105898839

TRU:	101077477 101078630(suz12)

TFS:	130514461 130526731(suz12b)

TNG:	GSTEN00004819G001 GSTEN00021272G001

LCO:	104923398 104929845

NCC:	104947975(suz12) 104950534

TBEN:

117481681(suz12b) 117492283

CGOB:

115012245(suz12) 115012408

PGEO:

117446518(suz12b) 117450533

GACU:

117537957(suz12b) 117539851

EMAC:

134864633(suz12b) 134877708

ELY:	117255362(suz12b) 117268062

EFO:	125879687 125884696(suz12b)

PLEP:

121941876(suz12b) 121956799

SLUC:

116040442(suz12b) 116063745

ECRA:

117951802(suz12b) 117957813

ESP:	116677843 116695237 116702950

PFLV:

114570357 114570747(suz12)

GAT:	120824965(suz12b) 120828042

PPUG:

119217353(suz12b) 119220196

AFB:	129096199(suz12b) 129098064

CLUM:

117734953(suz12b)

PSWI:

130188376 130189850(suz12b)

MSAM:

119884392 119894957 119899238(suz12b)

SCHU:

122869079 122872907(suz12b)

CUD:	121503845 121508685(suz12b)

ALAT:

119014237 119021188(suz12b)

MZE:	101466354 101485687(suz12)

ONL:	100692988(suz12) 100701898

OAU:	116314260 116320697(suz12b)

OLA:	101158330(suz12) 101158611

OML:	112146215 112157213(suz12b)

CSAI:

133450574(suz12b)

XMA:	102219079 102238308

XCO:	114144139 114160489

XHE:	116719719 116736222

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122822582 122829945

PPRL:

129373970

CVG:	107087701 107093481

CTUL:

119788477(suz12b) 119796889

GMU:	124862344 124863869 124868486

NFU:	107373105 107382213(suz12)

KMR:	108229693 108241543(suz12b)

ALIM:

106510968 106511494 106515221(suz12)

NWH:	119421061 119430444(suz12b)

AOCE:

111574076(suz12) 111576399

MCEP:

124997428 125004399(suz12b)

CSEM:

103384152(suz12)

POV:	109627703(suz12) 109634298

SSEN:

122770974(suz12b) 122785666

HHIP:

117760609(suz12b) 117765850

HSP:	118122250(suz12b) 118122968

SMAU:

118289092 118312303(suz12b)

LCF:	108875947 108888586

SDU:	111217592 111237701(suz12)

SLAL:

111650961(suz12) 111660588

XGL:	120785910 120799733(suz12b)

HCQ:	109511184(suz12) 109527711

SSCV:

125969377 125983105

SBIA:

133506775(suz12b) 133514936

PEE:	133403669(suz12b) 133414447

PTAO:

133466515 133477151(suz12b)

BPEC:

110160996 110172576(suz12)

MALB:

109958400(suz12) 109962828

BSPL:

114860513 114862047(suz12b)

SJO:	128377066(suz12b) 128378578

SASA:

106564652 106587302 106601962

STRU:

115152830 115153474 115178041 115208741

OTW:	112230303 112264331(suz12b)

OMY:	110485831(suz12b) 110495120 110519516 110538805

OGO:	124002539 124016449 124020309 124029327

ONE:	115103727 115142469

OKI:	109865779 109876373 109888739 116352974

OKE:	118364854 118376074 127918020 127925337

SALP:

112067974

SNH:	120032660 120036332 120036333 120066437

CCLU:

121533186 121551698 121570155 123485511

ELS:	105012261(suz12) 105031641

SFM:	108937453 108940108

PKI:	111833559 111853208

AANG:

118216821 118220067(suz12b)

LOC:	102688802(suz12)

PSPA:

121295774 121296411

ARUT:

117422879 117424079(suz12b)

PSEX:

120517995

LCM:	102363843(SUZ12)

CMK:	103175401(suz12b)

CPLA:

122562302

HOC:	132827902(suz12b)

LERI:

129708469

PMRN:

116949731(SUZ12)

LRJ:	133344679 133344874(SUZ12)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

AJC:

SKO:

DME:	Dmel_CG8013(Su(z)12)

DER:

6545760

DSE:

6619420

DSI:	Dsimw501_GD12239(Dsim_GD12239)

DYA:	Dyak_GE22454 Dyak_GE27419

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI11653

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:

AOQ:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

CQU:	CpipJ_CPIJ013585

CPII:

120424341

CNS:	116337982 116345031 116345033

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

AGRG:

ATD:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_213562

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:

PGW:

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

HVI:	124353750 124355573

MQU:	129002281 129002659

PHU:	Phum_PHUM186640

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_304723

DMK:

DPZ:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:	126981879 126992369

MNZ:	135207730 135207927

HAZT:

EAF:

LSM:

TCF:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

CSCU:

PTEP:

ABRU:

UDV:

SDM:

LOA:	LOAG_17336

LGI:	LOTGIDRAFT_71464

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CVN:	111119428 111120037

CANU:

OED:

MYI:

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

OBI:

OSN:

LAK:

SMM:	Smp_047720

SHX:	MS3_00004891(SUZ12_1)

OVI:	T265_09632

EGL:

EGR_04462

NVE:	116612140 5514532

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:	114519227 114541790

XEN:

124439430

HMG:

100203032

HSY:

130648769

TAD:	TRIADDRAFT_52904

AQU:

105313255

BRP:	103867276 103867335

BOE:

106340522

RSZ:

108809972

GSL:	Gasu_24890

TPS:	THAPSDRAFT_5265

PIF:	PITG_05508

PSOJ:

PHYSODRAFT_324933

» show all

Reference

PMID:15225548

Authors

Cao R, Zhang Y

Title

SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex.

Journal

Mol Cell 15:57-67 (2004)
DOI:10.1016/j.molcel.2004.06.020

Sequence

[hsa:23512]

LinkDB

DBGET integrated database retrieval system