KEGG ORTHOLOGY: K11716

ORTHOLOGY: K11716

Entry

K11716                      KO

Symbol

CDK5R1

Name

cyclin-dependent kinase 5 activator 1

Pathway

map05010

Alzheimer disease

map05022

Pathways of neurodegeneration - multiple diseases

map05030

Cocaine addiction

Brite

KEGG Orthology (KO) [BR:ko00001]
09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K11716  CDK5R1; cyclin-dependent kinase 5 activator 1
   05022 Pathways of neurodegeneration - multiple diseases
    K11716  CDK5R1; cyclin-dependent kinase 5 activator 1
  09165 Substance dependence
   05030 Cocaine addiction
    K11716  CDK5R1; cyclin-dependent kinase 5 activator 1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K11716  CDK5R1; cyclin-dependent kinase 5 activator 1
Membrane trafficking [BR:ko04131]
Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    K11716  CDK5R1; cyclin-dependent kinase 5 activator 1

Other DBs

GO:

0016534

Genes

HSA:	8851(CDK5R1)

PTR:	747897(CDK5R1)

PPS:	100984907(CDK5R1)

GGO:	101147584(CDK5R1)

PON:	100448505(CDK5R1)

PPYG:

129018350(CDK5R1)

NLE:	100596148(CDK5R1)

HMH:	116474473(CDK5R1)

SSYN:

129470457(CDK5R1)

MCC:	714274(CDK5R1)

MCF:	102128628(CDK5R1)

MTHB:

126938999

MNI:	105485186(CDK5R1)

CSAB:

103242698(CDK5R1)

CATY:

105589385(CDK5R1)

PANU:

101002671(CDK5R1)

TGE:	112610097(CDK5R1)

MLEU:

105548692(CDK5R1)

RRO:	104669329(CDK5R1)

RBB:	108541377(CDK5R1)

TFN:	117067542(CDK5R1)

PTEH:

111520261(CDK5R1)

CANG:

105508736(CDK5R1)

CJC:	100386175(CDK5R1)

SBQ:	101050024(CDK5R1)

CIMI:

108313689(CDK5R1)

ANAN:

105715061(CDK5R1)

CSYR:

103251066(CDK5R1)

MMUR:

105855005(CDK5R1)

LCAT:

123620323(CDK5R1)

PCOQ:

105813565(CDK5R1)

OGA:	100966496(CDK5R1)

MMU:	12569(Cdk5r1)

MCAL:

110305689(Cdk5r1)

MPAH:

110332117(Cdk5r1)

RNO:	116671(Cdk5r1)

MCOC:

116078527(Cdk5r1)

ANU:	117711468(Cdk5r1)

MUN:	110545105(Cdk5r1)

CGE:	100773660(Cdk5r1)

MAUA:

101841633(Cdk5r1)

PROB:

127218800(Cdk5r1)

PLEU:

114691546(Cdk5r1)

MORG:

121456653(Cdk5r1)

MFOT:

126492474

AAMP:

119813642(Cdk5r1)

NGI:	103746076(Cdk5r1)

HGL:	101725041(Cdk5r1)

CPOC:

100718674(Cdk5r1)

DORD:

105985857(Cdk5r1)

DSP:	122119897(Cdk5r1)

PLOP:

125365619(Cdk5r1)

NCAR:

124978832

MMMA:

107155303(Cdk5r1)

OCU:

100351850

OPI:	101530475(CDK5R1)

TUP:	102480500 102501561(CDK5R1)

GVR:	103589194(CDK5R1)

CFA:	491154(CDK5R1)

CLUD:

112655150(CDK5R1)

VVP:	112918004(CDK5R1)

VLG:	121472580(CDK5R1)

NPO:	129497386(CDK5R1)

AML:	100473330(CDK5R1)

UMR:	103667262(CDK5R1)

UAH:	113268986(CDK5R1)

UAR:	123777080(CDK5R1)

ELK:

111151672

LLV:

125087895

MPUF:

101682656(CDK5R1)

MNP:	132003575(CDK5R1)

MLK:	131816535(CDK5R1)

NVS:	122906451(CDK5R1)

ORO:	101372569(CDK5R1)

EJU:	114213862(CDK5R1)

ZCA:	113908192(CDK5R1)

MLX:	118025332(CDK5R1)

NSU:	110593103(CDK5R1)

LWW:	102736297(CDK5R1)

FCA:	101094890(CDK5R1)

PYU:	121017140(CDK5R1)

PCOO:

112854093(CDK5R1)

PBG:	122485213(CDK5R1)

PVIV:

125152177(CDK5R1)

LRUF:

124513070

PTG:	102968232(CDK5R1)

PPAD:

109251915(CDK5R1)

PUC:

125926821

AJU:

106985261

HHV:	120246179(CDK5R1)

BTA:	282173(CDK5R1)

BOM:	102284508(CDK5R1)

BIU:	109574425(CDK5R1)

BBUB:

102400547(CDK5R1)

BBIS:

105004173(CDK5R1)

CHX:	102187161(CDK5R1)

OAS:	101120847(CDK5R1)

BTAX:

128065372(CDK5R1)

ODA:	120866350(CDK5R1)

CCAD:

122449104(CDK5R1)

MBEZ:

129540088(CDK5R1)

SSC:	100113467(CDK5R1)

CFR:	102514233(CDK5R1)

CBAI:

105071609(CDK5R1)

CDK:	105088224(CDK5R1)

BACU:

103012840(CDK5R1)

BMUS:

118887419(CDK5R1)

LVE:	103089949(CDK5R1)

OOR:	101288300(CDK5R1)

DLE:	111185796(CDK5R1)

PCAD:

102979955(CDK5R1)

PSIU:

116746389(CDK5R1)

NASI:

112394514(CDK5R1)

ECB:	100071764(CDK5R1)

EPZ:	103551823(CDK5R1)

EAI:	106844625(CDK5R1)

MYB:	102241074(CDK5R1)

MYD:	102751511(CDK5R1)

MMYO:

118671771(CDK5R1)

MLF:	102433085(CDK5R1)

MDT:	132218374(CDK5R1)

PKL:	118728060(CDK5R1)

EFUS:

103291679(CDK5R1)

MNA:	107533043(CDK5R1)

DRO:	112308869(CDK5R1)

SHON:

119003609(CDK5R1)

AJM:	119047837(CDK5R1)

PDIC:

114504105(CDK5R1)

PHAS:

123817721(CDK5R1)

MMF:	118635026(CDK5R1)

PPAM:

129070131(CDK5R1)

HAI:	109385082(CDK5R1)

RFQ:	117013954(CDK5R1)

PALE:

102884715(CDK5R1)

PGIG:

120620914(CDK5R1)

PVP:	105291961(CDK5R1)

RAY:	107514644(CDK5R1)

MJV:	108394708(CDK5R1)

TOD:	119232257(CDK5R1)

SARA:

101543896(CDK5R1)

SETR:

126006952(CDK5R1)

LAV:	100667323(CDK5R1)

TMU:

101346082

ETF:	101639228(CDK5R1)

DNM:	101439815(CDK5R1)

MDO:	100018527(CDK5R1)

GAS:	123247356(CDK5R1)

SHR:	100915170(CDK5R1)

AFZ:

127558976

PCW:	110192281(CDK5R1)

TVP:	118858525(CDK5R1)

OAA:	100084018(CDK5R1)

GGA:	107055275(CDK5R1)

PCOC:

116233782(CDK5R1)

MGP:	104916156(CDK5R1)

CJO:	107325006(CDK5R1)

TPAI:

128088826(CDK5R1)

LMUT:

125684690(CDK5R1)

NMEL:

110388388(CDK5R1)

APLA:

101791735(CDK5R1)

ACYG:

125180020(CDK5R1)

CATA:

118258297(CDK5R1)

AFUL:

116498507(CDK5R1)

TGU:	115490613(CDK5R1)

LSR:	110475632(CDK5R1)

SCAN:

103821772(CDK5R1)

PMOA:

120498299(CDK5R1)

OTC:	121332995(CDK5R1)

PRUF:

121350560(CDK5R1)

FAB:	101814311(CDK5R1)

OMA:	130264260(CDK5R1)

PHI:	102113836(CDK5R1)

CCW:	120411318(CDK5R1)

ETL:	114068661(CDK5R1)

ZLE:	135458636(CDK5R1)

SVG:	106858245(CDK5R1)

HRT:	120763760(CDK5R1)

SATI:

136372183(CDK5R1)

FPG:

101924650

SHAB:

115617768(CDK5R1)

TALA:

116964991(CDK5R1)

ACHC:

115344211(CDK5R1)

HLE:	104828011(CDK5R1)

AGEN:

126038217

GCL:

127026404

EGZ:	104132310(CDK5R1)

CLV:	102097831(CDK5R1)

CUCA:

104064907(CDK5R1)

RTD:	128919239(CDK5R1)

AAM:	106495643(CDK5R1)

AROW:

112971104(CDK5R1)

NPD:	112951062(CDK5R1)

ASN:	102371983(CDK5R1) 102380785

AMJ:	102569867(CDK5R1) 102572662

CPOO:

109305907 109322841(CDK5R1)

GGN:	109291144 109302062(CDK5R1)

CMY:	102933126 119564547(CDK5R1)

CCAY:

125626585(CDK5R1) 125631108

DCC:	119848904(CDK5R1) 119851674

CPIC:

101931715(CDK5R1) 101948875

TST:	117869320(CDK5R1) 117871907

CABI:

116834127(CDK5R1) 116836139

MRV:	120385217(CDK5R1) 120396687

ACS:	100567431(cdk5r1)

ASAO:

132778330(CDK5R1) 132779066

PVT:	110081394(CDK5R1) 110082610

SUND:

121934362 121935360(CDK5R1)

PBI:	103050264 103060497(CDK5R1)

PMUR:

107286286 107297613 107298376

CTIG:

120296843 120302766(CDK5R1)

TSR:	106538798 106547034 106557249

PGUT:

117664743 132708872(CDK5R1)

APRI:

131197581 131198680(CDK5R1)

PTEX:

113447844(CDK5R1) 113453631

NSS:	113422606(CDK5R1) 113423573

VKO:	123017876 123031836(CDK5R1)

PMUA:

114581997(CDK5R1) 114607439

PRAF:

128399834(CDK5R1) 128423872

ZVI:	118092238 118095878(CDK5R1)

HCG:	128330527(CDK5R1) 128330616

GJA:	107120641(CDK5R1)

STOW:

125441104

EMC:	129337528 129340732(CDK5R1)

XLA:	108700847(cdk5r1.L) 108702549(cdk5r1.S) 108718669(cdk5r1l.L) 373685(cdk5r1l.S)

XTR:	100497533(cdk5r1) 100498128

NPR:	108785987(CDK5R1) 108801195

RTEM:

120919540(CDK5R1) 120941703

BBUF:

120985170 121000806 121002441 121004884(CDK5R1)

BGAR:

122923811 122939374 122939438 122939490 122939491 122939492 122939494 122939497 122940641

MUO:	115460031 115481990(CDK5R1)

GSH:	117347880(CDK5R1) 117355742

DRE:	436788(cdk5r1b) 568402(cdk5r1a) 571482(si:dkeyp-92c9.2)

SRX:	107709992 107731579 107738595 107743795 107753032 107754098

SANH:

107672824 107675021 107688088 107689695 107691215 107702702

SGH:	107565647 107568950 107571465 107577371 107598237 107601231

CCAR:

109059833 109068630 109071998 109076667 109076690 109094148

CAUA:

113044949 113068242 113074337 113100001 113111496 113119226

CGIB:

127934945 127950865 127952913 127968789 127978561(si:dkeyp-92c9.2)

PTET:

122324155(si:dkeyp-92c9.2) 122341714(cdk5r1a) 122355679(cdk5r1b)

LROH:

127158172(cdk5r1a) 127174455(cdk5r1b) 127181634(si:dkeyp-92c9.2)

OMC:	131525235(si:dkeyp-92c9.2) 131536066(cdk5r1a) 131551142(cdk5r1b)

PPRM:

120474551(cdk5r1b) 120485287(si:dkeyp-92c9.2) 120490311(cdk5r1a)

RKG:	130075851(cdk5r1a) 130087972(si:dkeyp-92c9.2) 130088761(cdk5r1b)

MAMB:

125254959(cdk5r1b) 125271152(cdk5r1a) 125274702(si:dkeyp-92c9.2)

CIDE:

127500568(si:dkeyp-92c9.2) 127510120 127523492

CERY:

137002004(si:dkeyp-92c9.2) 137007940(cdk5r1b) 137012315(cdk5r1a)

MASI:

127420923 127422937 127425668(si:dkeyp-92c9.2) 127426997 127450933 127451562

TROS:

130561511(cdk5r1a) 130566505(si:dkeyp-92c9.2) 130568742(cdk5r1b)

TDW:	130425516(cdk5r1a) 130438605(cdk5r1b)

MANU:

129421389(cdk5r1b) 129434398(cdk5r1a) 129455999(si:dkeyp-92c9.2)

IPU:	108272361(si:dkeyp-92c9.2) 108274057(cdk5r1b) 108275632

IFU:	128616248(si:dkeyp-92c9.2) 128616943(cdk5r1b) 128622646

PHYP:

113527091(cdk5r1) 113528407 113543732

SMEO:

124382253(si:dkeyp-92c9.2) 124388776(cdk5r1b) 124396934(cdk5r1a)

TFD:	113638902(cdk5r1b) 113659220(cdk5r1a) 113662761(si:dkeyp-92c9.2)

TVC:	132842711(si:dkeyp-92c9.2) 132859608(cdk5r1b) 132861126(cdk5r1a)

TRN:	134303784(si:dkeyp-92c9.2) 134319672 134321916(cdk5r1b)

AMEX:

103029482 103039239 103039635(si:dkeyp-92c9.2) 103044640 103047129(cdk5r1b) 103047254(cdk5r1a) 107196896 111192769 111192952 111193679 111194038 111194992 111195557 111195776 125781287 125781290 125786735 125786736

CMAO:

118797978 118797990 118797992 118805009(si:dkeyp-92c9.2) 118809452(cdk5r1b) 118821806(cdk5r1a)

EEE:	113569533 113582915 113588781 113589633

CHAR:

105888835(cdk5r1b) 105892165(si:dkeyp-92c9.2) 105907873

TRU:	101066331 101068959(cdk5r1) 101079452

TFS:	130514551 130518037(si:dkeyp-92c9.2) 130536400(cdk5r1b)

TNG:	GSTEN00006841G001 GSTEN00021070G001

LCO:	104925158(cdk5r1) 104926832 104935011

NCC:	104946097 104954977(cdk5r1) 104958043

TBEN:

117472045 117473359(cdk5r1b) 117475880 117477675(si:dkeyp-92c9.2)

CGOB:

115012622 115015969 115024974(cdk5r1)

PGEO:

117455651(si:dkeyp-92c9.2) 117464425(cdk5r1b)

GACU:

117547076(cdk5r1b) 117559311(si:dkeyp-92c9.2)

EMAC:

134870467(cdk5r1b) 134875304(si:dkeyp-92c9.2) 134878070

ELY:	117247451(cdk5r1b) 117263825(si:dkeyp-92c9.2) 117268016

EFO:	125879304 125881343(cdk5r1b) 125905305(si:dkeyp-92c9.2)

PLEP:

121956893 121958067(si:dkeyp-92c9.2) 121959376(cdk5r1b)

SLUC:

116047193(si:dkeyp-92c9.2) 116052936 116060970(cdk5r1b)

ECRA:

117937050(cdk5r1b) 117956934(si:dkeyp-92c9.2) 117957710

ESP:	116670847(cdk5r1) 116683398 116701273

PFLV:

114548673(cdk5r1) 114568527 114570315

GAT:	120819173(cdk5r1b) 120819765 120826057(si:dkeyp-92c9.2) 120827466

PPUG:

119213429(cdk5r1b) 119219605(si:dkeyp-92c9.2) 119220621

AFB:	129091690(cdk5r1b) 129097700(si:dkeyp-92c9.2) 129099034 129115766

CLUM:

117734895 117739152(si:dkeyp-92c9.2) 117748950(cdk5r1b)

PSWI:

130190365 130197137(si:dkeyp-92c9.2) 130203788(cdk5r1b)

MSAM:

119882392 119907913(si:dkeyp-92c9.2) 119916154(cdk5r1b)

SCHU:

122865015(si:dkeyp-92c9.2) 122867859(cdk5r1b) 122868410

CUD:	121503727 121524575(si:dkeyp-92c9.2) 121527935(cdk5r1b)

ALAT:

119009280(cdk5r1b) 119013257 119014796(si:dkeyp-92c9.2)

MZE:	101467445 101471295(cdk5r1) 101477257

ONL:	100690113 100704251 100706291(cdk5r1)

OAU:	116319542 116333546(si:dkeyp-92c9.2) 116335645(cdk5r1b)

OLA:	101161903 101162791(cdk5r1) 101174571

OML:	112136917(si:dkeyp-92c9.2) 112141961 112154508(cdk5r1b)

CSAI:

133419167(cdk5r1b) 133421947 133460966

XMA:	102218248(cdk5r1) 102222655 102232546

XCO:	114148283 114152205(cdk5r1) 114155887

XHE:	116727213(cdk5r1) 116731707 116735670

PRET:

103468291 103473007 103481711(cdk5r1)

PFOR:

103143475 103149224 103151995(cdk5r1)

PLAI:

106945117(cdk5r1) 106946878 106956272

PMEI:

106913241(cdk5r1) 106923559 106931821

GAF:	122821351 122823515(cdk5r1b) 122843782(si:dkeyp-92c9.2)

PPRL:

129363221 129367903(cdk5r1b) 129375970(si:dkeyp-92c9.2)

CVG:	107093186(cdk5r1) 107101840 107105186

CTUL:

119779894(si:dkeyp-92c9.2) 119791121(cdk5r1b) 119797427

GMU:	124863378 124864989 124875679(cdk5r1b) 124879933(si:dkeyp-92c9.2)

NFU:	107376207 107387614(cdk5r1) 107394948

KMR:	108246496(cdk5r1b) 108247079 108247913(si:dkeyp-92c9.2)

ALIM:

106521950(cdk5r1) 106525243 106530085

NWH:	119421463 119424163(cdk5r1b) 119425957(si:dkeyp-92c9.2)

AOCE:

111563588 111566416 111567364 111580960(cdk5r2)

MCEP:

124997411 125020505(si:dkeyp-92c9.2) 125022677(cdk5r1b)

CSEM:

103381863 103393664 103393941

POV:	109643143(cdk5r1) 109646495 109647512

SSEN:

122759686(cdk5r1b) 122785052 122786228(si:dkeyp-92c9.2)

HHIP:

117752950(cdk5r1b) 117766172 117770440(si:dkeyp-92c9.2)

HSP:	118100925(cdk5r1b) 118123592 118125085(si:dkeyp-92c9.2)

PPLT:

128426493(cdk5r1b) 128458978 128461753(si:dkeyp-92c9.2)

SMAU:

118287318(cdk5r1b) 118289463 118292153(si:dkeyp-92c9.2)

LCF:	108892018(cdk5r1b) 108898585 108899542(si:dkeyp-92c9.2)

SDU:	111220360(cdk5r1) 111223752 111230504

SLAL:

111655035 111655401(cdk5r1) 111662489

XGL:	120786942(si:dkeyp-92c9.2) 120788171 120794134(cdk5r1b)

HCQ:	109513649 109524734 109530169(cdk5r1)

SSCV:

125983068 125987355(si:dkeyp-92c9.2) 125991003

SBIA:

133490591(si:dkeyp-92c9.2) 133495682(cdk5r1b) 133514721

PEE:	133395990(si:dkeyp-92c9.2) 133415470 133417640(cdk5r1b)

PTAO:

133465836 133469592(cdk5r1b) 133471225(si:dkeyp-92c9.2)

BPEC:

110154413(cdk5r1) 110162656 110172843

MALB:

109951445 109958778 109962808(cdk5r1)

BSPL:

114846506(cdk5r1b) 114860638 114865969(si:dkeyp-92c9.2)

SJO:	128374275(si:dkeyp-92c9.2) 128379031 128381454(cdk5r1b)

SASA:

106570360 106579323 106583881 106589027 106589297 106600106 106600111 106600113 106600120 106600449 106600451 106600938

STRU:

115158473 115169446 115169447 115169478 115170865 115174098 115176208 115192095 115200939 115201049 115208359

OTW:	112223564 112224156 112226447 112227326 112229570 112234826 112236325 112252232 112258432 121841163 121841164

OMY:	110488094 110491493(cdk5r1b) 110496701 110499118 110508298 110508452 110521931 110523949 110537968 118944882 118944883 118944884 118944885 118944886 118944887