KEGG   ORTHOLOGY: K11812
Entry
K11812                      KO                                     
Symbol
CYP79B1_2
Name
tryptophan N-monooxygenase [EC:1.14.14.156]
Pathway
map00380  Tryptophan metabolism
map00966  Glucosinolate biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01210  2-Oxocarboxylic acid metabolism
Module
M00370  Glucosinolate biosynthesis, tryptophan => glucobrassicin
Reaction
R08160  L-tryptophan,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    K11812  CYP79B1_2; tryptophan N-monooxygenase
  09110 Biosynthesis of other secondary metabolites
   00966 Glucosinolate biosynthesis
    K11812  CYP79B1_2; tryptophan N-monooxygenase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K11812  CYP79B1_2; tryptophan N-monooxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.156  tryptophan N-monooxygenase
     K11812  CYP79B1_2; tryptophan N-monooxygenase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, plant type
  CYP79 family
   K11812  CYP79B1_2; tryptophan N-monooxygenase
Genes
ATH: AT4G39950(CYP79B2)
ALY: 9302968
CRB: 17879334
CSAT: 104716281 104720922 104729322 104729349
EUS: EUTSA_v10000278mg EUTSA_v10024861mg
BRP: 103835554 103853878 103862605
BNA: 106361376 106382592 106410467 106439341 106441279 125580497 125584456
BOE: 106301717 106302779 106330945
RSZ: 108818790 108819835 108830725 108855674 130507033 130507293 130507697 130511890
THJ: 104804164 104807687
TDC: 119320796
 » show all
Reference
PMID:10922360 (CYP79B2)
  Authors
Mikkelsen MD, Hansen CH, Wittstock U, Halkier BA
  Title
Cytochrome P450 CYP79B2 from Arabidopsis catalyzes the conversion of tryptophan to indole-3-acetaldoxime, a precursor of indole glucosinolates and indole-3-acetic acid.
  Journal
J Biol Chem 275:33712-7 (2000)
DOI:10.1074/jbc.M001667200
  Sequence
[ath:AT4G39950]
Reference
PMID:12464264 (CYP79B5)
  Authors
Naur P, Hansen CH, Bak S, Hansen BG, Jensen NB, Nielsen HL, Halkier BA
  Title
CYP79B1 from Sinapis alba converts tryptophan to indole-3-acetaldoxime.
  Journal
Arch Biochem Biophys 409:235-41 (2003)
DOI:10.1016/S0003-9861(02)00567-2
  Sequence
[brp:103853878]
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