KEGG   ORTHOLOGY: K12087
Entry
K12087                      KO                                     
Symbol
cag2
Name
cag pathogenicity island protein 2
Pathway
map05120  Epithelial cell signaling in Helicobacter pylori infection
Module
M00564  Helicobacter pylori pathogenicity signature, cagA pathogenicity island
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K12087  cag2; cag pathogenicity island protein 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02044 Secretion system
    K12087  cag2; cag pathogenicity island protein 2
Secretion system [BR:ko02044]
 Type IV secretion system
  Cag pathogenicity island (PAI) protein
   K12087  cag2; cag pathogenicity island protein 2
Other DBs
COG: COG0551
TC: 3.A.7.12.1
Genes
HEO: C694_02680
HPJ: jhp_0470(orf7)
HPG: HPG27_480
HPP: HPP12_0528(cag2)
HCA: HPPC18_02490
HPM: HPSJM_02680
HPE: HPELS_03940
HPI: hp908_0520
HPQ: hp2017_0502(cag2)
HPW: hp2018_0504(cag2)
HEN: HPSNT_02685
HPH: HPLT_02580
HEG: HPGAM_02660
HPN: HPIN_04295
HEU: HPPN135_02550
HER: C695_02680
HEI: C730_02680
HPYI: K750_04175
HEB: U063_0829
HEZ: U064_0832
 » show all
Reference
PMID:18178731
  Authors
Kutter S, Buhrdorf R, Haas J, Schneider-Brachert W, Haas R, Fischer W
  Title
Protein subassemblies of the Helicobacter pylori Cag type IV secretion system revealed by localization and interaction studies.
  Journal
J Bacteriol 190:2161-71 (2008)
DOI:10.1128/JB.01341-07
Reference
PMID:11886563
  Authors
Fischer W, Puls J, Buhrdorf R, Gebert B, Odenbreit S, Haas R
  Title
Systematic mutagenesis of the Helicobacter pylori cag pathogenicity island: essential genes for CagA translocation in host cells and induction of interleukin-8.
  Journal
Mol Microbiol 42:1337-48 (2001)
DOI:10.1046/j.1365-2958.2001.02714.x
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