KEGG   ORTHOLOGY: K12321
Entry
K12321                      KO                                     
Symbol
GUCY2D_E
Name
guanylate cyclase 2D/E [EC:4.6.1.2]
Pathway
map00230  Purine metabolism
map01100  Metabolic pathways
map04740  Olfactory transduction
map04744  Phototransduction
Disease
H00481  Cone-rod dystrophy and cone dystrophy
H00837  Leber congenital amaurosis
H01768  Central areolar choroidal dystrophy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K12321  GUCY2D_E; guanylate cyclase 2D/E
 09150 Organismal Systems
  09157 Sensory system
   04744 Phototransduction
    K12321  GUCY2D_E; guanylate cyclase 2D/E
   04740 Olfactory transduction
    K12321  GUCY2D_E; guanylate cyclase 2D/E
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K12321  GUCY2D_E; guanylate cyclase 2D/E
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.2  guanylate cyclase
     K12321  GUCY2D_E; guanylate cyclase 2D/E
Protein kinases [BR:ko01001]
 Serine/threonine kinases: Other
  RGC family [OT]
   K12321  GUCY2D_E; guanylate cyclase 2D/E
Other DBs
RN: R00434
GO: 0004383
Genes
HSA: 3000(GUCY2D)
PTR: 451435 750641(GUCY2D)
PPS: 100976525(GUCY2D) 100982348
GGO: 101140749(GUCY2D)
PON: 100443214(GUCY2D)
NLE: 100585866(GUCY2D) 100587777
MCC: 100430188 716734(GUCY2D)
MCF: 102146353(GUCY2D)
CSAB: 103242335(GUCY2D)
CATY: 105582008(GUCY2D)
PANU: 101013904(GUCY2D)
TGE: 112609922(GUCY2D)
RRO: 104661674(GUCY2D)
RBB: 108514277(GUCY2D)
TFN: 117067741(GUCY2D)
PTEH: 111527098(GUCY2D) 111540965
CJC: 100412242(GUCY2D)
SBQ: 101031889(GUCY2D)
CSYR: 103264653(GUCY2D) 103266817
MMUR: 105860273 105877334(GUCY2D)
OGA: 100945296 100959975(GUCY2D)
MMU: 14918(Gucy2d) 14919(Gucy2e)
MCAL: 110298578 110305918(Gucy2d)
MPAH: 110330114 110332384(Gucy2d)
RNO: 113911(Gucy2e) 79222(Gucy2d)
MCOC: 116077646(Gucy2d) 116101297
MUN: 110551701(Gucy2d) 110560570
CGE: 100750501 100754759(Gucy2d)
MAUA: 101837853(Gucy2d) 101843871
PLEU: 114693159(Gucy2d) 114698642
NGI: 103743062 103752104(Gucy2d)
HGL: 101697777(Gucy2d) 101717731
CPOC: 100732548(Gucy2d) 100735737
CCAN: 109688562 109693913(Gucy2d)
DORD: 105983282(Gucy2d) 105983940
DSP: 122100432(Gucy2d) 122113673
OCU: 100344095(GUCY2D)
OPI: 101525702(GUCY2D) 101527485
TUP: 102494681 102496410(GUCY2D)
CFA: 403863(GUCY2D) 485179
VVP: 112924739(GUCY2D) 112928727
VLG: 121476182 121499354(GUCY2D)
AML: 100476540 100480095(GUCY2D)
UMR: 103660485(GUCY2D) 103678130
UAH: 113269343 113271141(GUCY2D)
UAR: 123792118(GUCY2D) 123804220
MPUF: 101673015(GUCY2D) 101683029
ORO: 101377149 101383563(GUCY2D)
EJU: 114218609 114225449(GUCY2D)
ZCA: 113913683 113939024(GUCY2D)
MLX: 118000184(GUCY2D) 118004023
FCA: 101099582 101101009(GUCY2D)
PYU: 121015964(GUCY2D) 121039318
PBG: 122484234 122484918(GUCY2D)
PTG: 102960287(GUCY2D) 102971963
AJU: 106972445(GUCY2D) 106976443
HHV: 120229599 120231361(GUCY2D)
BTA: 282245(GUCY2D)
BOM: 102267198 102281141(GUCY2D)
BIU: 109574462(GUCY2D)
BBUB: 102406724(GUCY2D) 112579622
CHX: 102169418(GUCY2D)
OAS: 101109482 101120932(GUCY2D)
ODA: 120866023(GUCY2D) 120875958
CCAD: 122445557(GUCY2D) 122449330
SSC: 100523457 100625536(GUCY2D)
CFR: 102503713(GUCY2D) 102509037
CBAI: 105077586(GUCY2D) 105083617
CDK: 105098241 105102998(GUCY2D)
VPC: 102532665(GUCY2D) 107033440
BACU: 103002685 103016360(GUCY2D)
LVE: 103070106(GUCY2D)
OOR: 101274865 101282297(GUCY2D)
DLE: 111185889(GUCY2D)
PCAD: 102991189(GUCY2D)
PSIU: 116746475(GUCY2D)
ECB: 100073037(GUCY2D) 100630860
EPZ: 103548241 103566602(GUCY2D)
EAI: 106840416 106844230(GUCY2D)
MYB: 102242149 102243506(GUCY2D)
MYD: 102751706(GUCY2D) 102760543
MMYO: 118664217 118672108(GUCY2D)
MLF: 102430842 102435067(GUCY2D)
MNA: 107524472 107544495(GUCY2D)
PKL: 118713730 118727033(GUCY2D)
HAI: 109395113(GUCY2D)
DRO: 112308750(GUCY2D)
SHON: 118974632(GUCY2D) 118981631
AJM: 119049023(GUCY2D)
PDIC: 114515200(GUCY2D)
PHAS: 123805339 123809404(GUCY2D)
MMF: 118627780 118634460(GUCY2D)
RFQ: 117013594(GUCY2D)
PALE: 102884807 102892708(GUCY2D)
PGIG: 120589911(GUCY2D) 120590531
PVP: 105291238(GUCY2D) 105297649
RAY: 107515672(GUCY2D) 107519122
MJV: 108383381(GUCY2D) 108398545
TOD: 119231504(GUCY2D) 119255046
SARA: 101538539 101539935(GUCY2D)
LAV: 100656347 100670740(GUCY2D)
DNM: 101430783(GUCY2D) 101442492
MDO: 100014788(GUCY2D) 100028110
GAS: 123241224(GUCY2F) 123245158(GUCY2D)
SHR: 100921433(GUCY2D)
PCW: 110194405(GUCY2D) 110210716
NMEL: 110391669
APLA: 101805092
ACYG: 106049690
TGU: 115492653
OTC: 121340599
PRUF: 121362549
PHI: 102114027(GUCY2D)
FPG: 101916520
FCH: 102050145
CLV: 102095707
NNI: 104015339
AAM: 106487682
AROW: 112964210
DNE: 112995512
ASN: 102375187(GUCY2D)
AMJ: 102564997(GUCY2D)
PSS: 102451086(GUCY2D)
CMY: 102946484(GUCY2D)
CPIC: 101953314
TST: 117869962(GUCY2D)
CABI: 116839656(GUCY2D)
MRV: 120381502(GUCY2D)
ACS: 100558820(gucy2d)
PVT: 110087765(GUCY2D)
SUND: 121934439(GUCY2D)
PBI: 103064925(GUCY2D)
PMUR: 107297126
TSR: 106557179
PGUT: 117671248(GUCY2D)
VKO: 123016599(GUCY2D)
ZVI: 118095007(GUCY2D)
XLA: 108703527(gucy2d.S) 108711755(gucy2d.L)
XTR: 100496590(gucy2d)
NPR: 108793773(GUCY2D)
RTEM: 120933532(GUCY2D)
BBUF: 120987271(GUCY2D)
DRE: 140426(gucy2d)
SRX: 107734113
SANH: 107661246
PPRM: 120470177(gucy2d)
MAMB: 125266951(gucy2d)
IPU: 108259769(gucy2d)
PHYP: 113531167
SMEO: 124379516(gucy2d)
TFD: 113641486(gucy2d)
AMEX: 111191814
EEE: 113586825
CGOB: 115005249
ELY: 117246109
ECRA: 117940923
PFLV: 114546096
GAT: 120822615
PPUG: 119223384
MSAM: 119894851(gucy2d) 119913480
CUD: 121504669
ALAT: 119026608
ONL: 100708131
OAU: 116334465
OLA: 100192404(olgc3)
XMA: 102238353
XCO: 114143094
XHE: 116709368
PRET: 103465677
PFOR: 103149387
PLAI: 106961303
PMEI: 106906648
GAF: 122835599
CVG: 107083206
CTUL: 119780419
GMU: 124878347
NFU: 107383747
KMR: 108250633
ALIM: 106534425
NWH: 119414353
AOCE: 111584162
CSEM: 103390041(gucy2d) 103395410
SSEN: 122766047
HHIP: 117779228
HSP: 118102840
XGL: 120797535 120802631(gucy2d)
MALB: 109959424
BSPL: 114865278
OMY: 110534896(gucy2d) 110537393
AANG: 118223909 118236272(gucy2d)
PSPA: 121305656
LCM: 102362141(GUCY2D)
CRG: 105318117
MMER: 123554762
 » show all
Reference
PMID:1356371
  Authors
Shyjan AW, de Sauvage FJ, Gillett NA, Goeddel DV, Lowe DG
  Title
Molecular cloning of a retina-specific membrane guanylyl cyclase.
  Journal
Neuron 9:727-37 (1992)
DOI:10.1016/0896-6273(92)90035-C
  Sequence
[hsa:3000]
Reference
  Authors
Venkataraman V, Duda T, Ravichandran S, Sharma RK
  Title
Neurocalcin delta modulation of ROS-GC1, a new model of Ca(2+) signaling.
  Journal
Biochemistry 47:6590-601 (2008)
DOI:10.1021/bi800394s
  Sequence
[hsa:3000]
Reference
  Authors
Coleman JE, Semple-Rowland SL
  Title
GC1 deletion prevents light-dependent arrestin translocation in mouse cone photoreceptor cells.
  Journal
Invest Ophthalmol Vis Sci 46:12-6 (2005)
DOI:10.1167/iovs.04-0691
  Sequence
[mmu:14919]
LinkDB

DBGET integrated database retrieval system