KEGG   ORTHOLOGY: K12321
Entry
K12321                      KO                                     

Name
GUCY2D_E
Definition
guanylate cyclase 2D/E [EC:4.6.1.2]
Pathway
ko00230  Purine metabolism
ko01100  Metabolic pathways
ko04740  Olfactory transduction
ko04744  Phototransduction
Disease
H00481  Cone-rod dystrophy and cone dystrophy
H00837  Leber congenital amaurosis
H01768  Central areolar choroidal dystrophy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K12321  GUCY2D_E; guanylate cyclase 2D/E
 09150 Organismal Systems
  09157 Sensory system
   04744 Phototransduction
    K12321  GUCY2D_E; guanylate cyclase 2D/E
   04740 Olfactory transduction
    K12321  GUCY2D_E; guanylate cyclase 2D/E
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K12321  GUCY2D_E; guanylate cyclase 2D/E
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.2  guanylate cyclase
     K12321  GUCY2D_E; guanylate cyclase 2D/E
Protein kinases [BR:ko01001]
 Serine/threonine kinases: Other
  RGC family [OT]
   K12321  GUCY2D_E; guanylate cyclase 2D/E
Other DBs
RN: R00434
GO: 0004383
Genes
HSA: 3000(GUCY2D)
PTR: 451435 750641(GUCY2D)
PPS: 100976525(GUCY2D)
GGO: 101140749(GUCY2D)
PON: 100443214(GUCY2D)
NLE: 100585866(GUCY2D) 100587777
MCC: 100430188 716734(GUCY2D)
MCF: 102146353(GUCY2D)
CSAB: 103242335(GUCY2D)
CATY: 105582008(GUCY2D)
RRO: 104661674(GUCY2D)
RBB: 108514277(GUCY2D)
TFN: 117067741(GUCY2D)
CJC: 100412242(GUCY2D)
SBQ: 101031889(GUCY2D)
MMUR: 105860273 105877334(GUCY2D)
MMU: 14918(Gucy2d) 14919(Gucy2e)
MCAL: 110298578 110305918(Gucy2d)
MPAH: 110330114 110332384(Gucy2d)
RNO: 113911(Gucy2e) 79222(Gucy2d)
MCOC: 116077646(Gucy2d) 116101297
MUN: 110551701(Gucy2d) 110560570
CGE: 100750501 100754759(Gucy2d)
PLEU: 114693159(Gucy2d) 114698642
NGI: 103743062 103752104(Gucy2d)
HGL: 101697777(Gucy2d) 101717731
CCAN: 109688562 109693913(Gucy2d)
OCU: 100344095(GUCY2D)
TUP: 102494681 102496410(GUCY2D)
CFA: 403863(GUCY2D) 485179
VVP: 112924739(GUCY2D) 112928727
AML: 100476540 100480095(GUCY2D)
UMR: 103660485(GUCY2D) 103678130
UAH: 113269343 113271141(GUCY2D)
ORO: 101377149 101383563(GUCY2D)
MPUF: 101673015(GUCY2D) 101683029
EJU: 114218609 114225449(GUCY2D)
FCA: 101099582 101101009(GUCY2D)
PTG: 102960287(GUCY2D) 102971963
AJU: 106972445(GUCY2D) 106976443
BTA: 282245(GUCY2D)
BOM: 102267198 102281141(GUCY2D)
BIU: 109574462(GUCY2D)
BBUB: 102406724(GUCY2D)
CHX: 102169418(GUCY2D)
OAS: 101109482 101120932(GUCY2D)
SSC: 100523457 100625536(GUCY2D)
CFR: 102503713(GUCY2D) 102509037
CDK: 105098241 105102998(GUCY2D)
BACU: 103002685 103016360(GUCY2D)
LVE: 103070106(GUCY2D)
OOR: 101274865 101282297(GUCY2D)
DLE: 111185889(GUCY2D)
PCAD: 102991189(GUCY2D)
ECB: 100073037(GUCY2D) 100630860
EPZ: 103548241 103566602(GUCY2D)
EAI: 106840416 106844230(GUCY2D)
MYB: 102242149 102243506(GUCY2D)
MYD: 102751706(GUCY2D) 102760543
MMYO: 118664217 118672108(GUCY2D)
MNA: 107524472 107544495(GUCY2D)
HAI: 109395113(GUCY2D)
DRO: 112308750(GUCY2D)
SHON: 118974632(GUCY2D) 118981631
AJM: 119049023(GUCY2D)
MMF: 118627780 118634460(GUCY2D)
PALE: 102884807 102892708(GUCY2D)
RAY: 107515672(GUCY2D) 107519122
MJV: 108383381(GUCY2D) 108398545
LAV: 100656347 100670740(GUCY2D)
MDO: 100014788(GUCY2D) 100028110
SHR: 100921433(GUCY2D)
PCW: 110194405(GUCY2D) 110210716
NMEL: 110391669
APLA: 101805092
ACYG: 106049690
TGU: 115492653
PHI: 102114027(GUCY2D)
FPG: 101916520
FCH: 102050145
CLV: 102095707
NNI: 104015339
AAM: 106487682
ASN: 102375187(GUCY2D)
AMJ: 102564997(GUCY2D)
PSS: 102451086(GUCY2D)
CMY: 102946484(GUCY2D)
CPIC: 101953314(GUCY2F)
ACS: 100558820(gucy2d)
PVT: 110087765(GUCY2D)
PBI: 103064925(GUCY2D)
PMUR: 107297126
TSR: 106557179
XLA: 108703527(gucy2d.S) 108711755(gucy2d.L)
XTR: 100496590(gucy2d)
NPR: 108793773(GUCY2D)
DRE: 140426(gucy2d)
SRX: 107734113
SANH: 107661246
IPU: 108259769
PHYP: 113531167
AMEX: 111191814
EEE: 113586825
ONL: 100708131
OLA: 100192404(olgc3)
XMA: 102238353
XCO: 114143094
PRET: 103465677
CVG: 107083206
NFU: 107383747
KMR: 108250633
ALIM: 106534425
AOCE: 111584162
CSEM: 103390041(gucy2d) 103395410
MALB: 109959424
LCM: 102362141(GUCY2D)
 » show all
Reference
PMID:1356371
  Authors
Shyjan AW, de Sauvage FJ, Gillett NA, Goeddel DV, Lowe DG
  Title
Molecular cloning of a retina-specific membrane guanylyl cyclase.
  Journal
Neuron 9:727-37 (1992)
DOI:10.1016/0896-6273(92)90035-C
  Sequence
[hsa:3000]
Reference
  Authors
Venkataraman V, Duda T, Ravichandran S, Sharma RK
  Title
Neurocalcin delta modulation of ROS-GC1, a new model of Ca(2+) signaling.
  Journal
Biochemistry 47:6590-601 (2008)
DOI:10.1021/bi800394s
  Sequence
[hsa:3000]
Reference
  Authors
Coleman JE, Semple-Rowland SL
  Title
GC1 deletion prevents light-dependent arrestin translocation in mouse cone photoreceptor cells.
  Journal
Invest Ophthalmol Vis Sci 46:12-6 (2005)
DOI:10.1167/iovs.04-0691
  Sequence
[mmu:14919]
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