KEGG   ORTHOLOGY: K12431
Entry
K12431                      KO                                     
Symbol
pks2
Name
phthioceranic/hydroxyphthioceranic acid synthase [EC:2.3.1.287]
Reaction
R12380  (S)-methylmalonyl-CoA:palmitoyl-[(hydroxy)phthioceranic acid synthase] methylmalonyltransferase (phthioceranyl-[(hydroxy)phthioceranic acid synthase]-forming)
R12381  (S)-methylmalonyl-CoA:palmitoyl-[(hydroxy)phthioceranic acid synthase] methylmalonyltransferase (phthioceranyl-[(hydroxy)phthioceranic acid synthase]-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins
    K12431  pks2; phthioceranic/hydroxyphthioceranic acid synthase
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.287  phthioceranic/hydroxyphthioceranic acid synthase
     K12431  pks2; phthioceranic/hydroxyphthioceranic acid synthase
Lipid biosynthesis proteins [BR:ko01004]
 Polyketide synthase
  Modular PKS
   K12431  pks2; phthioceranic/hydroxyphthioceranic acid synthase
Other DBs
COG: COG3321
Genes
BOB: GN304_08335
BOMB: GT348_07885
MTU: Rv3825c(pks2)
MTV: RVBD_3825c
MTC: MT3933(mas-3)
MRA: MRA_3865(pks2)
MTF: TBFG_13859
MTB: TBMG_03872
MTK: TBSG_03895
MTZ: TBXG_003842
MTUR: CFBS_4055
MTO: MTCTRI2_3904(pks2)
MTD: UDA_3825c(pks2)
MTN: ERDMAN_4192(pks2)
MTUE: J114_20440
MTUH: I917_26895
MTUL: TBHG_03763
MTUT: HKBT1_4038(pks2)
MTUU: HKBT2_4048(pks2)
MTQ: HKBS1_4051(pks2)
MBO: BQ2027_MB3855C(pks2)
MBB: BCG_3888c(pks2)
MBT: JTY_3890(pks2)
MBM: BCGMEX_3889c(pks2)
MBX: BCGT_3690
MAF: MAF_38400(pks2)
MMIC: RN08_4223
MCE: MCAN_38441(pks2)
MCQ: BN44_120235(pks)
MCV: BN43_90342(pks)
MCX: BN42_90353(pks)
MCZ: BN45_110187(pks)
MORY: MO_003977(pks2)
MPA: MAP_3764c(pks2)
MBAI: MB901379_03143(pks2_3)
MGAU: MGALJ_24090(pks2)
 » show all
Reference
  Authors
Sirakova TD, Thirumala AK, Dubey VS, Sprecher H, Kolattukudy PE
  Title
The Mycobacterium tuberculosis pks2 gene encodes the synthase for the hepta- and octamethyl-branched fatty acids required for sulfolipid synthesis.
  Journal
J Biol Chem 276:16833-9 (2001)
DOI:10.1074/jbc.M011468200
  Sequence
[mtu:Rv3825c]
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