KEGG   ORTHOLOGY: K12633
Entry
K12633            Tight     KO                                     
Symbol
pur5
Name
N-methyl-transferase [EC:2.1.1.-]
Pathway
map00998  Biosynthesis of various antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00889  Puromycin biosynthesis, ATP => puromycin
Reaction
R05673  
R05674  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00998 Biosynthesis of various antibiotics
    K12633  pur5; N-methyl-transferase
Genes
SALW: CP975_29295
Reference
PMID:8576156
  Authors
Tercero JA, Espinosa JC, Lacalle RA, Jimenez A.
  Title
The biosynthetic pathway of the aminonucleoside antibiotic puromycin, as deduced from the molecular analysis of the pur cluster of Streptomyces alboniger.
  Journal
J Biol Chem 271:1579-90 (1996)
DOI:10.1074/jbc.271.3.1579
  Sequence
[salw:CP975_29295]
LinkDB

KEGG   REACTION: R05673
Entry
R05673                      Reaction                               
Definition
N-Acetyl-N6,N6,O-tridemethylpuromycin-5'-phosphate + S-Adenosyl-L-methionine <=> N-Acetyl-N6,O-didemethylpuromycin-5'-phosphate + S-Adenosyl-L-homocysteine
Equation
C07028 + C00019 <=> C07029 + C00021
Comment
Pur5
Ref.1. The Journal of Biological chemistry; vol.271, No.3, Jan 19,
pp.1579-1590, 1996
Reaction class
RC00003  C00019_C00021
RC00335  C07028_C07029
Enzyme
2.-.-.-
Pathway
rn00998  Biosynthesis of various antibiotics
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00889  Puromycin biosynthesis, ATP => puromycin
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.-  
   2.-.-  
    2.-.-.-
     R05673  N-Acetyl-N6,N6,O-tridemethylpuromycin-5'-phosphate + S-Adenosyl-L-methionine <=> N-Acetyl-N6,O-didemethylpuromycin-5'-phosphate + S-Adenosyl-L-homocysteine
Orthology
K12633  N-methyl-transferase [EC:2.1.1.-]
LinkDB

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