KEGG ORTHOLOGY: K12749

ORTHOLOGY: K12749

Entry

K12749                      KO

Symbol

MYL3

Name

myosin light chain 3

Pathway

map04260

Cardiac muscle contraction

map04261

Adrenergic signaling in cardiomyocytes

map04371

Apelin signaling pathway

map04814

Motor proteins

map04820

Cytoskeleton in muscle cells

map05410

Hypertrophic cardiomyopathy

map05414

Dilated cardiomyopathy

Disease

H00292

Hypertrophic cardiomyopathy

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K12749  MYL3; myosin light chain 3
09140 Cellular Processes
  09142 Cell motility
   04814 Motor proteins
    K12749  MYL3; myosin light chain 3
   04820 Cytoskeleton in muscle cells
    K12749  MYL3; myosin light chain 3
09150 Organismal Systems
  09153 Circulatory system
   04260 Cardiac muscle contraction
    K12749  MYL3; myosin light chain 3
   04261 Adrenergic signaling in cardiomyocytes
    K12749  MYL3; myosin light chain 3
09160 Human Diseases
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    K12749  MYL3; myosin light chain 3
   05414 Dilated cardiomyopathy
    K12749  MYL3; myosin light chain 3
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K12749  MYL3; myosin light chain 3
Cytoskeleton proteins [BR:ko04812]
Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     K12749  MYL3; myosin light chain 3

Genes

HSA:	4634(MYL3)

PTR:	460327(MYL3)

PPS:	100994049(MYL3)

GGO:	101130342(MYL3)

PON:	100174572(MYL3)

PPYG:

129033403(MYL3)

NLE:	100583112(MYL3)

HMH:	116473542(MYL3)

SSYN:

129483002(MYL3)

MCC:	712209(MYL3)

MCF:	102117313(MYL3)

MTHB:

126948600

MNI:	105480374(MYL3)

CSAB:

103227553(MYL3)

CATY:

105573617(MYL3)

PANU:

100997992(MYL3)

TGE:	112618748(MYL3)

MLEU:

105540417(MYL3)

RRO:	104671315(MYL3)

RBB:	108517652(MYL3)

TFN:	117080296(MYL3)

PTEH:

111555506(MYL3)

CANG:

105509762(MYL3)

CJC:	100402415(MYL3)

SBQ:	101033364(MYL3)

CIMI:

108298531(MYL3)

ANAN:

105707531(MYL3)

CSYR:

103273785(MYL3)

MMUR:

105874892(MYL3)

LCAT:

123623144(MYL3)

PCOQ:

105805742(MYL3)

OGA:	100955666(MYL3)

MMU:	17897(Myl3)

MCAL:

110301920(Myl3)

MPAH:

110328443(Myl3)

RNO:	24585(Myl3)

MCOC:

116072338(Myl3)

ANU:	117693450(Myl3)

ASYL:

127689585(Myl3)

MUN:	110554994(Myl3)

CGE:	100766026(Myl3)

MAUA:

101830975(Myl3)

PROB:

127235944(Myl3)

PLEU:

114705242(Myl3)

MORG:

121464393(Myl3)

MFOT:

126499923

AAMP:

119810352(Myl3)

NGI:	103732019(Myl3)

HGL:	101716754(Myl3)

CPOC:

100718060(Myl3)

CCAN:

109701071(Myl3)

DORD:

105996264(Myl3)

DSP:	122095699(Myl3)

PLOP:

125342294(Myl3)

NCAR:

124969421

MMMA:

107145411(Myl3)

ITI:	101967880(Myl3)

OCU:

100347740

OPI:	101536163(MYL3)

TUP:	102474564(MYL3)

GVR:	103591235(MYL3)

CFA:	476644(MYL3)

CLUD:

112666845(MYL3)

VVP:	112913253(MYL3)

VLG:	121496293(MYL3)

NPO:	129521946(MYL3)

AML:	100466054(MYL3) 117799519

UMR:	103675121(MYL3)

UAH:	113256802(MYL3)

UAR:	123780003(MYL3)

ELK:

111143787

LLV:

125081109

MPUF:

101686212(MYL3)

MNP:	132011256(MYL3)

MLK:	131823860(MYL3)

NVS:	122909488(MYL3)

ORO:	101363411(MYL3)

EJU:	114196439(MYL3)

ZCA:	113917801(MYL3)

MLX:	118005172(MYL3)

NSU:	110577670(MYL3)

LWW:	102725813(MYL3)

FCA:	101084780(MYL3)

PYU:	121011120(MYL3)

PCOO:

112852639(MYL3)

PBG:	122487194(MYL3)

PVIV:

125160353(MYL3)

LRUF:

124524844

LGF:	123605591(MYL3)

AJU:

106969037

PTG:	102953715(MYL3)

PPAD:

109247726(MYL3)

PUC:

125929299

PLEZ:

122213377(MYL3)

HHV:	120229352(MYL3)

BTA:	618352(MYL3)

BOM:	102264943(MYL3)

BIU:	109576315(MYL3)

BBUB:

102396703(MYL3)

BBIS:

105004689(MYL3)

CHX:	102175068(MYL3)

OAS:	101115408(MYL3)

BTAX:

128044416(MYL3)

CSUM:

138087293(MYL3)

ODA:	120868174(MYL3)

CCAD:

122424804(MYL3)

MREE:

136167843(MYL3)

OVR:	110152298(MYL3)

MBEZ:

129547771(MYL3)

SSC:	100515755(MYL3)

CFR:	102513520(MYL3)

CBAI:

105072924(MYL3)

CDK:	105103584(MYL3)

VPC:	102536227(MYL3)

BACU:

102999204(MYL3)

BMUS:

118903926(MYL3)

LVE:	103085123(MYL3)

OOR:	101277071(MYL3)

LALB:

132527075(MYL3)

DLE:	111174466(MYL3)

PCAD:

102978650(MYL3)

PSIU:

116762302(MYL3)

NASI:

112403797(MYL3)

ECB:	100054327(MYL3)

EPZ:	103551037(MYL3)

EAI:	106823258(MYL3)

MYB:	102258821(MYL3)

MYD:	102768945(MYL3)

MMYO:

118668544(MYL3)

MLF:	102422271(MYL3)

MDT:	132215185(MYL3)

MYUM:

138992385(MYL3)

PKL:	118714797(MYL3)

EFUS:

103299167(MYL3)

MNA:	107529383(MYL3)

DRO:	112309882(MYL3)

SHON:

118976233(MYL3)

AJM:	119037779(MYL3)

PDIC:

114501932(MYL3)

PHAS:

123830596(MYL3)

MMF:	118633240(MYL3)

PPAM:

129087771(MYL3)

HAI:	109375284(MYL3)

RFQ:	117036644(MYL3)

PALE:

102892357(MYL3)

PGIG:

120581972(MYL3)

PVP:	105302340(MYL3)

RAY:	107509109(MYL3)

MJV:	108396488(MYL3)

TOD:	119259253(MYL3)

SARA:

101552119(MYL3)

SFUM:

130037626(MYL3)

SETR:

126014099(MYL3)

LAV:	100656780(MYL3)

TMU:

101342128

ETF:	101644677(MYL3)

DNM:	101446422(MYL3)

MDO:	100018980(MYL3)

GAS:	123230815(MYL3)

SHR:	100932686(MYL3)

PCW:	110217119(MYL3)

TVP:	118831634(MYL3)

PBRV:

138166963(MYL3)

OAA:	100080927(MYL3)

TACU:

119936366(MYL3)

GGA:	396067(MYL3)

PCOC:

116238242(MYL3)

MGP:	100538682(MYL3)

CJO:	107308825(MYL3)

TPAI:

128086919(MYL3)

LMUT:

125696329(MYL3)

NMEL:

110394307(MYL3)

APLA:

101804464(MYL3)

ACYG:

106036876(MYL3)

CATA:

118251806(MYL3)

AFUL:

116486250(MYL3)

LSR:	110476935(MYL3)

SCAN:

103812673(MYL3)

PMOA:

120510605(MYL3)

OTC:	121338172(MYL3)

PRUF:

121351810(MYL3)

ATRC:

139605003(MYL3)

GFR:	102037456(MYL3)

FAB:	101820982(MYL3)

OMA:	130249505(MYL3)

PHI:	102114016(MYL3)

PMAJ:

107215438(MYL3)

CCAE:

111925574(MYL3)

CCW:	104686379(MYL3)

CBRC:

103623914(MYL3)

ACOE:

138106136(MYL3)

ETL:

114071430

ZLE:	135443519(MYL3)

ACHL:

103801019

SVG:	106862793(MYL3)

MMEA:

130574542(MYL3)

HRT:	120760922(MYL3)

SATI:

136375031(MYL3)

CCIC:

134044099(MYL3)

FPG:	101911020(MYL3)

FCH:	102053884(MYL3)

CCRI:

104156496

NNT:	104399542(MYL3)

SHAB:

115608520(MYL3)

ACUN:

113476596(MYL3)

TALA:

104363801(MYL3)

ACHC:

115339877(MYL3)

HALD:

104314702

HLE:	104828260(MYL3)

AGEN:

126037924

HHAR:

128151428(MYL3)

GCL:

127013002

CSTI:

104554256

LDI:	104352198(MYL3)

MNB:	103773863(MYL3)

DPUB:

104306772(MYL3)

PPUS:

135185806(MYL3)

AVIT:

104274584

BRHI:

104495658

EGZ:	104127426(MYL3)

NNI:	104021723(MYL3)

PCRI:

104038614(MYL3)

PCAO:

104049122

PADL:

103924701(MYL3)

AFOR:

103900361(MYL3)

FGA:	104075147(MYL3)

GSTE:

104254004(MYL3)

CLV:	102094328(MYL3)

MUI:	104548674(MYL3)

PGUU:

104468860(MYL3)

PLET:

104623825(MYL3)

EHS:	104510744(MYL3)

CMAC:

104474947

CUCA:

104055033(MYL3)

TEO:	104373238(MYL3)

BREG:

104642438(MYL3)

OHA:	104332875(MYL3)

ACAR:

104532442

CPEA:

104393545(MYL3)

CVF:	104282417(MYL3)

RTD:	128906006(MYL3)

CRID:

134510980(MYL3)

AAM:	106485299(MYL3)

AROW:

112977425(MYL3)

NPD:	112947561(MYL3)

TGT:	104566442(MYL3)

DNE:	112980749(MYL3)

SCAM:

104150112(MYL3)

ASN:	102376376(MYL3)

AMJ:	102565509(MYL3)

CPOO:

109306343(MYL3)

GGN:	109291162(MYL3)

PSS:	102460214(MYL3)

CMY:	102941102(MYL3)

CCAY:

125631134(MYL3)

DCC:	119851246(MYL3)

CPIC:

101942875(MYL3)

TST:	117871925(MYL3)

CABI:

116823959(MYL3)

MRV:	120398117(MYL3)

ACS:	100557845(myl3)

ASAO:

132779811(MYL3)

PVT:

110085110

SUND:

121918198 121935690(MYL3)

PBI:

103060920

PMUR:

107286016(MYL3)

CTIG:

120318044(MYL3)

TSR:

106540512

PGUT:

117660094

APRI:

131196751(MYL3)

PTEX:

113451223

VKO:	123020771(MYL3)

PMUA:

114607612(MYL3)

PRAF:

128423975(MYL3)

ZVI:	118092137(MYL3)

HCG:	128331796(MYL3)

GJA:

107123952

STOW:

125440656(MYL3)

EMC:	129337571(MYL3)

XLA:	398607(myl3.S)

XTR:	394608(myl3)

BBUF:

121002039(MYL3)

BGAR:

122922870 122939246

PWL:	138261694(MYL3)

MUO:	115466131(MYL3)

GSH:	117354394(MYL3)

AMEX:

103034677(zgc:163073)

TRU:

101061450

TFS:	130538335(myl13)

TNG:	GSTEN00016127G001

LCO:

104917696

NCC:	104942410(myl3)

TBEN:

117488793(myl13)

CGOB:

115022984

PGEO:

117462380(myl13)

GACU:

117558396(myl13)

EMAC:

134866385(myl13)

ELY:	117272251(myl13)

EFO:	125901759(myl13)

PLEP:

121951310(myl13)

SLUC:

116045963(myl13)

ECRA:

117954759(myl13)

ESP:

116699548

PFLV:

114565271

GAT:	120816600(myl13)

PPUG:

119207582(myl13)

AFB:	129112628(myl13)

CLUM:

117746390(myl13)

CANA:

137804663(myl13)

CVE:	137892648(myl13)

MSAM:

119901984(myl13)

SCHU:

122887218(myl13)

CUD:	121520177(myl13)

SPUL:

138611434(myl13)

LMIX:

132979268(myl13)

ALAT:

119011172(myl13)

ASTR:

137612791(myl13)

MZE:

101476377

ONL:

100693213

OAU:	116316223(myl13)

OLA:

101157250

OML:	112140108 112147526(myl13)

CSAI:

133452809(myl13)

XMA:

102217899

XCO:

114146921

XHE:

116722075

PFOR:

103135743(myl3)

PLAI:

106948797(myl3)

PMEI:

106914248(myl3)

GAF:	122841307(myl13)

PPRL:

129361953(myl13)

CVG:	107081728(myl3)

CTUL:

119794150(myl13)

GMU:	124869979(myl13)

NFU:

107395748

KMR:	108241640(myl13)

ALIM:

106533199(myl3)

NWH:	119414677(myl13)

AOCE:

111568623(myl13)

EJA:	138203060(myl13)

BFRE:

138617316(myl13)

MCEP:

125010116(myl13)

CSEM:

103396388(myl3)

POV:

109640970

SSEN:

122762329(myl13)

SSOE:

131459379(myl13)

HHIP:

117777695(myl13)

HSP:	118118411(myl13)

PPLT:

128454636(myl13)

SMAU:

118311563(myl13)

LCF:	108883346(myl13)

SDU:

111230999

SLAL:

111653239

XGL:	120798562(myl13)

HCQ:

109521149

SSCV:

125984647(myl13)

SBIA:

133510533(myl13)

PEE:	133411134(myl13)

PTAO:

133489091(myl13)

BPEC:

110158347

ENY:	140356627(myl13)

MALB:

109955390

BSPL:

114843908(myl13)

SJO:	128368948(myl13)

SSCO:

133990272(myl13)

GMH:

115549550

SASA:

100136504(MLEC) 100194663

STRU:

115157208 115169569

OTW:	112226781 112260649

OMY:	110487529 110508567(myl13) 110530496

OGO:

124009930

ONE:	115101759 115114576

OKI:	109872005 109875174

OKE:	118395133 118401949

OMM:	135512319 135558254

OCLA:

139376182 139386954

SALP:

111956293 111978968

SNH:	120020046 120055331

CCLU:

121535366 121581054

ELS:

105019866

OEP:	134036443(myl13)

LOC:	102683186(myl3)

LCM:	102358075(MYL3)

RTP:

CPLA:

HOC:

LERI:

Reference

PMID:3417683

Authors

Kurabayashi M, Komuro I, Tsuchimochi H, Takaku F, Yazaki Y

Title

Molecular cloning and characterization of human atrial and ventricular myosin alkali light chain cDNA clones.

Journal

J Biol Chem 263:13930-6 (1988)

Sequence

[hsa:4634]

LinkDB

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