KEGG ORTHOLOGY: K12750

ORTHOLOGY: K12750

Entry

K12750                      KO

Symbol

MYL4

Name

myosin light chain 4

Pathway

map04260

Cardiac muscle contraction

map04261

Adrenergic signaling in cardiomyocytes

map04371

Apelin signaling pathway

map04814

Motor proteins

map04820

Cytoskeleton in muscle cells

Disease

H00731

Atrial fibrillation

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K12750  MYL4; myosin light chain 4
09140 Cellular Processes
  09142 Cell motility
   04814 Motor proteins
    K12750  MYL4; myosin light chain 4
   04820 Cytoskeleton in muscle cells
    K12750  MYL4; myosin light chain 4
09150 Organismal Systems
  09153 Circulatory system
   04260 Cardiac muscle contraction
    K12750  MYL4; myosin light chain 4
   04261 Adrenergic signaling in cardiomyocytes
    K12750  MYL4; myosin light chain 4
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K12750  MYL4; myosin light chain 4
Cytoskeleton proteins [BR:ko04812]
Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     K12750  MYL4; myosin light chain 4

Genes

HSA:	4635(MYL4)

PTR:	454814(MYL4)

PPS:	100973937(MYL4)

GGO:	101148883(MYL4)

PON:	100444983(MYL4)

PPYG:

129017916(MYL4)

NLE:	100594384(MYL4)

HMH:	116475014(MYL4)

SSYN:

129470178(MYL4)

MCC:	717354(MYL4)

MCF:	102143592(MYL4)

MTHB:

126939928

MNI:	105483065(MYL4)

CSAB:

103243275(MYL4)

CATY:

105590704(MYL4)

PANU:

101011515(MYL4)

TGE:	112609453(MYL4)

MLEU:

105534548(MYL4)

RRO:	104662520(MYL4)

RBB:	108536301(MYL4)

TFN:	117067473(MYL4)

PTEH:

111526565(MYL4)

CANG:

105526546(MYL4)

CJC:	100415216(MYL4)

SBQ:	101031337(MYL4)

CIMI:

108318300(MYL4)

ANAN:

105711355(MYL4)

CSYR:

103252912(MYL4)

MMUR:

105863661(MYL4)

LCAT:

123620571(MYL4)

ERUF:

138391684(MYL4)

PCOQ:

105819073(MYL4)

OGA:	100949754(MYL4)

MMU:	17896(Myl4)

MCAL:

110305335(Myl4)

MPAH:

110332070(Myl4)

RNO:	688228(Myl4)

MCOC:

116078419(Myl4)

ANU:	117710814(Myl4)

ASYL:

127693798(Myl4)

MUN:	110545657(Myl4)

CGE:	100771007(Myl4)

MAUA:

101834801(Myl4)

PROB:

127221500(Myl4)

PLEU:

114702283(Myl4)

PMAV:

102905830(Myl4)

MORG:

121436246(Myl4)

MFOT:

126487532

AAMP:

119812998(Myl4)

CNL:	130877968(Myl4)

NGI:	103724764(Myl4)

HGL:	101716492(Myl4)

CPOC:

100713818(Myl4)

CCAN:

109696586(Myl4)

DORD:

105998529(Myl4)

DSP:	122103323(Myl4)

DMER:

138830853(Myl4)

PLOP:

125366523(Myl4)

NCAR:

124980434

MMMA:

107160517(Myl4)

ITI:	101965247(Myl4)

OCU:

100345621

OPI:

101520724

OCZ:	121162278(MYL4) 121162400

TUP:	102475162(MYL4)

GVR:

103583623

CFA:	480490(MYL4)

CLUD:

112652977(MYL4)

VVP:	112920591(MYL4)

VLG:	121473279(MYL4)

NPO:	129513943(MYL4)

AML:	100475266(MYL4)

UMR:	103665614(MYL4)

UAH:	113265310(MYL4)

UAR:	123802916(MYL4)

ELK:

111158127

LLV:

125087137

MPUF:

101677363(MYL4)

MNP:	132004391(MYL4)

MLK:	131815769(MYL4)

NVS:	122906103(MYL4)

ORO:	101370256(MYL4)

EJU:	114196726(MYL4)

ZCA:	113939318(MYL4)

MLX:	118027183(MYL4)

MANO:

123853898(MYL4)

NSU:	110570378(MYL4)

LWW:	102740680(MYL4)

FCA:	100316866(MYL4)

PYU:	121020151(MYL4)

PCOO:

112861981(MYL4)

PBG:	122485741(MYL4)

PVIV:

125151291(MYL4)

LRUF:

124512881

LGF:	123603876(MYL4)

AJU:

106988849

PTG:	102969488(MYL4)

PPAD:

109259741(MYL4)

PUC:

125927342

PLEZ:

122205885 122207375(MYL4) 122212767

HHV:	120244252(MYL4)

CCRU:

144244988(MYL4)

BTA:	504201(MYL4)

BOM:	102269199(MYL4)

BIU:	109573406(MYL4)

BBUB:

102390547(MYL4)

BKE:	129651168(MYL4)

BBIS:

104982946(MYL4)

CHX:	102168763(MYL4)

OAS:	101121691(MYL4)

BTAX:

128065119(MYL4)

CSUM:

138083884(MYL4)

ODA:	120866979(MYL4)

CCAD:

122440007(MYL4)

MREE:

136148930(MYL4)

OVR:	110131400(MYL4)

MBEZ:

129537875(MYL4)

SSC:	100516998(MYL4)

CFR:	102511774(MYL4)

CBAI:

105069805(MYL4)

CDK:	105090430(MYL4)

VPC:	102530507(MYL4)

BACU:

103005624(MYL4)

BMUS:

118886619(MYL4)

LVE:	103069828(MYL4)

OOR:	101275610(MYL4)

LALB:

132511545(MYL4)

GMF:	115849104(MYL4)

DDP:	132415141(MYL4)

DLE:	111182587(MYL4)

PCAD:

102988459(MYL4)

PSIU:

116745693 116746470

PPHC:

136139242(MYL4)

NASI:

112410321(MYL4)

ECB:	100054510(MYL4)

EPZ:	103560743(MYL4)

EAI:	106836500(MYL4)

MYB:	102262432(MYL4)

MYD:	102761232(MYL4)

MMYO:

118672405(MYL4)

MLF:	102422090(MYL4)

MDT:	132217841(MYL4)

MYUM:

138993807(MYL4)

PKL:	118726331(MYL4)

EFUS:

103293160(MYL4)

MNA:	107531022(MYL4)

DRO:	112316415(MYL4)

SHON:

119003700(MYL4)

AJM:	119062691(MYL4)

PDIC:

114503279(MYL4)

PHAS:

123817377(MYL4)

MMF:	118634328(MYL4)

PPAM:

129071525(MYL4)

HAI:	109380256(MYL4)

RFQ:	117012674(MYL4)

PALE:

102881447(MYL4)

PGIG:

120589272(MYL4)

PVP:	105303515(MYL4)

RAY:	107508180(MYL4)

MJV:	108396089(MYL4)

TOD:	119232943(MYL4)

SARA:

101558278(MYL4)

SFUM:

130035799(MYL4)

SETR:

126019663(MYL4)

LAV:	100665527(MYL4)

TMU:

101359616

ETF:	101652842(MYL4)

DNM:	101436878(MYL4)

MDO:	100021133(MYL4)

GAS:	123246192(MYL4)

SHR:	100913949(MYL4)

AFZ:

127560388

PCW:	110215795(MYL4)

TVP:	118847480(MYL4)

PBRV:

138152438(MYL4)

MLAO:

141514003(MYL4)

OAA:	100087899(MYL4)

TACU:

119934831(MYL4)

GGA:	396472(MYL4)

PCOC:

116233806(MYL4)

MGP:	100543339(MYL4)

CJO:	107325141(MYL4)

TPAI:

128088738(MYL4)

LMUT:

125684661(MYL4)

NMEL:

110388475(MYL4)

APLA:

101791820(MYL4)

AACU:

137844614

OJA:	118178851(MYL4)

ACYG:

106045949

CATA:

118258896(MYL4)

AFUL:

116498381(MYL4)

TGU:

LSR:

VMC:

VCHA:

AIB:	137486576(MYL4)

SCAN:

103821661(MYL4)

PMOA:

120498210

OTC:

121347631

PRUF:

121352476

ATRC:

139601826(MYL4)

MATE:

118696762

GFR:	102031521(MYL4)

FAB:

101816985

OMA:

130264038

PHI:

102113085

PMAJ:

107215266(MYL4)

CCAE:

111939923(MYL4)

CCW:

104698635

CBRC:

103619887(MYL4)

ACOE:

138099493

ETL:

114066937

ZAB:	102060954(MYL4)

ZLE:

ACHL:

SVG:

MMEA:

HRT:

SATI:

CFAI:

CCIC:

FPG:

FCH:	102047288(MYL4)

CCRI:

104163230

NNT:	104408975(MYL4)

SHAB:

115617910(MYL4)

ACUN:

113489241

ANOC:

141970105

TALA:

104362733(MYL4)

ACHC:

115344383(MYL4)

HALD:

104319928

HLE:	104827987(MYL4)

AGEN:

HHAR:

BBUT:

GCL:

LDI:	104348945(MYL4)

MNB:	103775316(MYL4)

DPUB:

104309220(MYL4)

PPUS:

135191834

IIN:

128978467

AVIT:

104272512(MYL4)

BRHI:

104490791(MYL4)

EGZ:	104127028(MYL4)

NNI:	104012258(MYL4)

PCRI:

104033362(MYL4)

PCAO:

104046810(MYL4)

PARX:

142068036(MYL4)

PADL:

103913877(MYL4)

AFOR:

103906071(MYL4)

FGA:	104077311(MYL4)

CBOR:

142091858

GSTE:

104252401

CBOY:

140662298(MYL4)

MAME:

142419881(MYL4)

MUI:	104537637(MYL4)

PGUU:

104469631(MYL4)

PLET:

104615614

CUCA:

104054382

TEO:	104381160(MYL4)

BREG:

104640616(MYL4)

GAME:

129195338

OHA:	104338689(MYL4)

ACAR:

104525820(MYL4)

CPEA:

104397965(MYL4)

CVF:	104285387(MYL4)

RTD:

128919123

CRID:

134524574(MYL4)

NARQ:

141474896

AAM:	106497421(MYL4)

NPD:	112960264(MYL4)

TGT:	104574511(MYL4)

DNE:	112982771(MYL4)

SCAM:

104144782(MYL4)

ASN:	102376762(MYL4)

AMJ:	102571199(MYL4)

CPOO:

109318952(MYL4)

GGN:	109302102(MYL4)

PSS:	102453002(MYL4)

CIZ:	142002656(MYL4)

CMY:	102931763(MYL4)

CCAY:

125626860(MYL4)

LKP:

140903792

NDS:

141978401

DCC:	119848930(MYL4)

CPIC:

101930898(MYL4)

TST:	117869406(MYL4)

EOB:	135894471(MYL4)

CABI:

116831364(MYL4)

ACS:	100558684(myl4)

ASAO:

132778294(MYL4)

PVT:

110082051

SUND:

121932470(MYL4)

PBI:	103059639(MYL4)

PMUR:

107303059(MYL4)

CTIG:

120315199(MYL4)

TSR:	106556907(MYL4)

PGUT:

117664688

APRI:

131196634

PTEX:

113447402(MYL4)

NSS:	113420027(MYL4) 113429306

VKO:	123031796(MYL4)

PMUA:

114582326

PRAF:

128399892(MYL4)

ZVI:

118094626

HCG:

128330415

GJA:	107118448(MYL4)

STOW:

125445201(MYL4)

EMC:	129338589 129339070 129339093

XLA:	100037107(myl4.S) 373844(myl4.L)

XTR:	100124786(myl4)

NPR:	108802637(MYL4)

RTEM:

120919585(MYL4)

ACAT:

141114124(MYL4)

PADS:

140333125(MYL4)

BBUF:

121004825(MYL4)

BGAR:

122940868(MYL4)

DTC:	141096030(MYL4)

HSQ:

130296740

PCOB:

135055434(MYL4)

PWL:	138299616(MYL4)

MUO:	115481717(MYL4)

GSH:	117347615(MYL4)

DRE:	100037358(zgc:163073) 141385692 574004(myl4) 64671(cmlc1)

SRX:	107708955 107732170 107740645 107754315

SANH:

107653918 107662407 107664608 107694961

SGH:	107557349 107568487 107585102 107598675

CCAR:

109047525(myl4) 109052177 109080042 109087734 109099519 109099905 122137486(cmlc1)

CAUA:

113048175 113056383 113112245

CGIB:

127942857 127957160 127957162 127969344 127988805 127989724 128025035

PTET:

122341712(myl4) 122344834 122344887 122345840 122346141 122355223(zgc:163073)

LROH:

127155734(myl4) 127164734(cmlc1) 127165583 127173845(zgc:163073)

GRF:	141297402 141297592 141323219(myl4) 141334664(cmlc1) 141334668

OMC:	131537148(myl4) 131540894(cmlc1) 131540931 131551467(zgc:163073)

PPRM:

120469452(zgc:163073) 120471866 120479720 120479861 120489453(myl4)

RKG:	130070270(myl4) 130071847(cmlc1) 130080574(zgc:163073) 130089423

MAMB:

125244942 125255421(zgc:163073) 125267619(cmlc1) 125267651 125272620(myl4)

CIDE:

127508044 127512690 127512892 127524230(zgc:163073)

CERY:

137007441(zgc:163073) 137010696(myl4) 137033721(cmlc1)

MASI:

127423133(zgc:163073) 127426415 127428381 127436177 127440114 127450531 127451596

TROS:

130548900(cmlc1) 130555945 130561334(myl4) 130571229

TDW:	130419335(cmlc1) 130419437 130425653(myl4) 130427458

MANU:

129436387(myl4) 129440777 129440989(cmlc1) 129451502

PDAB:

135733543 135768525(myl4) 135774112 135774539(cmlc1)

IPU:	108255383 108259731 108272405 108273504(zgc:163073)

IFU:	128603825 128616163(myl4) 128617492(zgc:163073) 128625698(cmlc1)

PHYP:

113527501 113531068 113543886

SMEO:

124379128 124380637(cmlc1) 124382019(myl4) 124388807(zgc:163073)

TFD:	113637609(cmlc1) 113646577 113653577(zgc:163073) 113662808(myl4)

TVC:	132841295 132842675(myl4) 132855336(cmlc1) 132860264(zgc:163073)

CGAR:

128509334(cmlc1) 128512265 128516178(myl4)

NGRA:

132870698(myl4) 132872743(cmlc1) 132876126 132897559(zgc:163073)

TRN:	134303025 134309221(myl4) 134335096(cmlc1)

AMEX:

103024626(cmlc1) 103026687(myl4) 103026881

CMAO:

118803664(myl4) 118808905(zgc:163073) 118815122 118827608(cmlc1)

EEE:	113567933 113587833

CHAR:

105890718(myl4) 105895780(cmlc1) 105903357 105913012

SPIL:

134070629 134076511(myl4) 134088353(cmlc1) 134101299

ASAD:

121680759 121699885 121705035(myl4) 121716112(cmlc1)

TRU:

101063574

TFS:	130517139(cmlc1)

TNG:	GSTEN00034685G001

LCO:	104931894 109142454

NCC:

104957373

TBEN:

117476329

CGOB:

115016636

PGEO:

117455773(cmlc1)

GACU:

117538892(cmlc1)

EMAC:

134868947(cmlc1)

ELY:	117268643(myl4) 117269269

EFO:	125879186(myl4) 125906188

PLEP:

121959705 121966858

SLUC:

116054857 116063540(myl4)

ECRA:

117941310 117959608

ESP:	116678220 116704666

PFLV:

GAT:

PPUG:

AFB:

CLUM:

PSWI:

CANA:

CVE:

MSAM:

119896174(myl4) 119914006

SCHU:

EARM:

CUD:

SPUL:

LMIX:

HTC:

ASTR:

137608912 137609311(myl4)

PKLU:

139216206(myl4) 139218576

MZE:	101483891(cmlc1)

ONL:

100694366

OAU:	116331884(cmlc1)

OLA:

OML:

CSAI:

XMA:

XCO:

XHE:

PRET:

PFOR:

PLAI:

PMEI:

GAF:

PPRL:

CVG:

CTUL:

GMU:

NFU:

KMR:

ALIM:

NWH:

AOCE:

EJA:

BFRE:

MCEP:

124996154(cmlc1) 124997921(myl4)

CSEM:

POV:

SSEN:

SSOE:

HHIP:

117772090(cmlc1)

HSP:

118098049

PPLT:

128424874

SMAU:

118285497

LCF:	108873229 108874130(cmlc1)

SDU:	111230416 111238509

SLAL:

111649333 111664749

XGL:	120788377(myl4) 120806890

HCQ:

SSCV:

SBIA:

PEE:

PTAO:

BPEC:

ENY:

MALB:

SJO:	128378553(myl4) 128380049

SSCO:

133995110 133998907(myl4)

TTY:	137171106(cmlc1)

GMH:

115532583

SASA:

100196435(myl4) 106600870

STRU:

115170944 115193024

OTW:	112225812 112233494 112248900(cmlc1) 112259399(myl4)

OMY:	110509818 110526071(cmlc1) 110539156(myl4)

OGO:	123999981(myl4) 124007158 124033202(cmlc1)

ONE:

115109849

OKI:

109892214

OKE:	118384757(myl4) 118385282 118393577(cmlc1)

OMM:	135543915 135555058(myl4) 135555466(cmlc1)

OCLA:

139411236 139422508

SALP:

111981341

SNH:	120021566 120044468(myl4) 120055594(cmlc1)

SFON:

129853984(cmlc1) 129863240 129868990

CCLU:

121541171 121550496 121570581(myl4) 121581754 121584577

ELS:	105023360(myl4)

OEP:	134038986(cmlc1)

SFM:	108924846 108941718

PKI:	111843447 111856076

AANG:

118213107 118216496(myl4) 118219839(zgc:163073) 118237408(cmlc1)

AROT:

135239738 135243487(myl4) 135247846(zgc:163073) 135265193

CCOG:

133114535(myl4) 133119182(zgc:163073) 133140388 133141988

LOC:	102684478(myl4)

PSPA:

121303501 121303508 121303606 121303608 121313371 121325036(myl4)

ARUT:

117396784 117396978 117400458 117422148 117422580 117433480 117434585(myl4)

PSEX:

120517606(myl4) 120529665(myl13) 120535137(cmlc1)

LCM:	102358220(MYL4)

RTP:

109918399

CPLA:

122540034(myl4)

CPUN:

140465928(myl4)

HOC:	132831022(myl4)

SCAU:

119954251 119972366

STOZ:

140398325 140398330

LERI:

129710247(myl4)

HAKA:

140729592 140741083

PMRN:

116938540 116943785 116948741

LRJ:	133346107 133355643

RES:

135696348

» show all

Reference

PMID:2849544

Authors

Arnold HH, Lohse P, Seidel U, Bober E

Title

A novel human myosin alkali light chain is developmentally regulated. Expression in fetal cardiac and skeletal muscle and in adult atria.

Journal

Eur J Biochem 178:53-60 (1988)
DOI:10.1111/j.1432-1033.1988.tb14428.x

Sequence

[hsa:4635]

LinkDB

DBGET integrated database retrieval system