KEGG   ORTHOLOGY: K12904
Entry
K12904            Tight     KO                                     
Symbol
phpC
Name
phosphonoacetaldehyde reductase [EC:1.1.1.309]
Pathway
map00440  Phosphonate and phosphinate metabolism
map00998  Biosynthesis of various antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Reaction
R09478  2-hydroxyethylphosphonate:NAD+ oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00440 Phosphonate and phosphinate metabolism
    K12904  phpC; phosphonoacetaldehyde reductase
  09110 Biosynthesis of other secondary metabolites
   00998 Biosynthesis of various antibiotics
    K12904  phpC; phosphonoacetaldehyde reductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.309  phosphonoacetaldehyde reductase (NADH)
     K12904  phpC; phosphonoacetaldehyde reductase
Genes
AG: AAU00078(phpC)
Reference
PMID:15616300
  Authors
Blodgett JA, Zhang JK, Metcalf WW
  Title
Molecular cloning, sequence analysis, and heterologous expression of the phosphinothricin tripeptide biosynthetic gene cluster from Streptomyces viridochromogenes DSM 40736.
  Journal
Antimicrob Agents Chemother 49:230-40 (2005)
DOI:10.1128/AAC.49.1.230-240.2005
  Sequence
[ag:AAU00078]
Reference
PMID:19489722
  Authors
Metcalf WW, van der Donk WA
  Title
Biosynthesis of phosphonic and phosphinic acid natural products.
  Journal
Annu Rev Biochem 78:65-94 (2009)
DOI:10.1146/annurev.biochem.78.091707.100215
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