Entry |
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Symbol |
AIM2
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Name |
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Pathway |
map04621 | NOD-like receptor signaling pathway |
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Brite |
KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
K12966 AIM2; absent in melanoma 2
04623 Cytosolic DNA-sensing pathway
K12966 AIM2; absent in melanoma 2
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Genes |
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Reference |
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Authors |
Hornung V, Ablasser A, Charrel-Dennis M, Bauernfeind F, Horvath G, Caffrey DR, Latz E, Fitzgerald KA |
Title |
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. |
Journal |
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Reference |
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Authors |
Burckstummer T, Baumann C, Bluml S, Dixit E, Durnberger G, Jahn H, Planyavsky M, Bilban M, Colinge J, Bennett KL, Superti-Furga G |
Title |
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome. |
Journal |
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Reference |
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Authors |
DeYoung KL, Ray ME, Su YA, Anzick SL, Johnstone RW, Trapani JA, Meltzer PS, Trent JM |
Title |
Cloning a novel member of the human interferon-inducible gene family associated with control of tumorigenicity in a model of human melanoma. |
Journal |
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Sequence |
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LinkDB |
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