KEGG   ORTHOLOGY: K12993
Entry
K12993                      KO                                     

Name
wbdA, mtfA
Definition
O-antigen biosynthesis alpha-1,2-mannosyltransferase [EC:2.4.1.371 2.4.1.-]
Pathway
ko00542  O-Antigen repeat unit biosynthesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00542 O-Antigen repeat unit biosynthesis
    K12993  wbdA, mtfA; O-antigen biosynthesis alpha-1,2-mannosyltransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01005 Lipopolysaccharide biosynthesis proteins
    K12993  wbdA, mtfA; O-antigen biosynthesis alpha-1,2-mannosyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.371  polymannosyl GlcNAc-diphospho-ditrans,octacis-undecaprenol 2,3-alpha-mannosylpolymerase
     K12993  wbdA, mtfA; O-antigen biosynthesis alpha-1,2-mannosyltransferase
    2.4.1.-  
     K12993  wbdA, mtfA; O-antigen biosynthesis alpha-1,2-mannosyltransferase
Lipopolysaccharide biosynthesis proteins [BR:ko01005]
 O-antigen repeat unit
  K12993  wbdA, mtfA; O-antigen biosynthesis alpha-1,2-mannosyltransferase
Other DBs
COG: COG0438
CAZy: GT4
Genes
ECX: EcHS_A2168
SBG: SBG_0616(wbdA)
SBZ: A464_689
SBV: N643_03105
KPJ: N559_1772
KVA: Kvar_1570
KPE: KPK_1680
KVD: KR75_26280
KVQ: SP68_06425
KQU: AVR78_21670
AG: AGH30276(wbdA)
 » show all
Reference
PMID:7536735
  Authors
Kido N, Torgov VI, Sugiyama T, Uchiya K, Sugihara H, Komatsu T, Kato N, Jann K
  Title
Expression of the O9 polysaccharide of Escherichia coli: sequencing of the E. coli O9 rfb gene cluster, characterization of mannosyl transferases, and evidence for an ATP-binding cassette transport system.
  Journal
J Bacteriol 177:2178-87 (1995)
DOI:10.1128/jb.177.8.2178-2187.1995
  Sequence
Reference
  Authors
Kido N, Kobayashi H
  Title
A single amino acid substitution in a mannosyltransferase, WbdA, converts the Escherichia coli O9 polysaccharide into O9a: generation of a new O-serotype group.
  Journal
J Bacteriol 182:2567-73 (2000)
DOI:10.1128/jb.182.9.2567-2573.2000
  Sequence
Reference
  Authors
Greenfield LK, Richards MR, Li J, Wakarchuk WW, Lowary TL, Whitfield C
  Title
Biosynthesis of the polymannose lipopolysaccharide O-antigens from Escherichia coli serotypes O8 and O9a requires a unique combination of single- and multiple-active site mannosyltransferases.
  Journal
J Biol Chem 287:35078-91 (2012)
DOI:10.1074/jbc.M112.401000
  Sequence
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