KEGG   ORTHOLOGY: K13016
Entry
K13016                      KO                                     
Symbol
wbpB
Name
UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase [EC:1.1.1.335]
Pathway
map00520  Amino sugar and nucleotide sugar metabolism
map00541  O-Antigen nucleotide sugar biosynthesis
map01100  Metabolic pathways
map01250  Biosynthesis of nucleotide sugars
Reaction
R10140  UDP-N-acetyl-2-amino-2-deoxy-alpha-D-glucuronate:NAD+ 3-oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00520 Amino sugar and nucleotide sugar metabolism
    K13016  wbpB; UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase
  09107 Glycan biosynthesis and metabolism
   00541 O-Antigen nucleotide sugar biosynthesis
    K13016  wbpB; UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.335  UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase
     K13016  wbpB; UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase
Other DBs
COG: COG0673
Genes
PVC: G3341_19065
MSU: MS1500(mviM)
BSUN: A4G13_04960
ASU: Asuc_0110
AAZ: ADJ80_05775
DJI: CH75_07775
DJA: HY57_11970
DYE: EO087_12210
DCS: ISN74_19545
DTL: H8F01_18615
VTU: IX91_00690
PAE: PA3158(wbpB)
PAEV: N297_3269(wbpB)
PAEI: N296_3269(wbpB)
PAEM: U769_09132
PAEC: M802_3267(wbpB)
PAEO: M801_3134(wbpB)
PMY: Pmen_1858
PPUH: B479_06900
PAZO: AYR47_15420
PBA: PSEBR_a1558
PDR: H681_23225
PSES: PSCI_2866
PSOS: POS17_4987
PSET: THL1_1977
PXA: KSS93_10395(wbpB)
PANH: HU763_007130(wbpB)
PCAV: D3880_03190
PHF: NLY38_15670
PSIH: LOY51_07390
PHOM: KJF94_22335(wbpB)
MSR: AU15_01125
MARI: ACP86_02340
MARA: D0851_05440
MARJ: MARI_04640(wbpB)
PCR: Pcryo_0614
PRW: PsycPRwf_0247
PALI: A3K91_0139 A3K91_0719
PSYP: E5677_09790 E5677_12790
ACB: A1S_0053
ABK: LX00_00465
ABW: BL01_01445
ACC: BDGL_002972
ACD: AOLE_19130
AID: CTZ23_14935
ADS: FPL17_13950
ACHI: CDG60_01075
ASHA: G8E00_00505
AVIV: LF296_18080
SAZ: Sama_2259
SSE: Ssed_2972
SSEM: JYB85_11890
SGLA: FJ709_05395
SVM: KDH10_000086
SRHS: K0I63_07035
IPI: CEW91_09915
IDI: CWC33_02945
PSEO: OM33_04950
PLZ: S4054249_18600
PPIS: B1L02_14600
PXI: J5O05_07160
PVB: J5X90_03255 J5X90_03345
PSAZ: PA25_03820(wbpB)
PFLI: CTT31_02695
PMAZ: R5H13_02710
AAUS: EP12_05245
LAL: AT746_12775
CATE: C2869_15620
PAEW: KIH87_04760
ALKM: NKI27_13880
SDE: Sde_0872
AFUS: EYZ66_11590
MBUR: EQU24_04405
FRX: F7310_06790
FRL: FIP56_02755
TMB: Thimo_0036
THIM: KFB96_04800
TLR: Thiosp_00142(wbpB_1) Thiosp_04203(wbpB_2)
SPIZ: GJ672_09095
HAHE: ENC22_10775
HAHH: O5O45_01625
HCO: LOKO_02148(wbpB)
HALO: BWR19_11915
HSV: HNO53_09795
HPIZ: GYM47_15080
HTT: HZS52_20505
HCAM: I4484_08290 I4484_11335
HSX: HNO51_07700 HNO51_11040
HTX: EKK97_08735 EKK97_12330
ADI: B5T_01708(wbpB)
MMW: Mmwyl1_0822
MPRI: MP3633_3247
MFOI: JSY38_06740
MRHI: KDW99_03190
TOR: R615_06290
MGEO: CFI10_13645
OME: OLMES_5515
SUTR: L0B52_04095
VFF: VITFI_CDS0485
RPJ: N234_28855
REH: H16_B0033(wbpB)
CUU: BKK79_06660
COX: E0W60_06205
AXY: AXYL_06286
AIS: BUW96_24710
TEQ: TEQUI_1006
TEA: KUI_0407
TEG: KUK_0147
AAMM: FE795_15360
ODI: ODI_R2826
OUE: I6G29_01505
PNA: Pnap_3129
AJS: Ajs_3015
ACK: C380_07385
ACIP: CBP36_03010
ACIS: CBP35_15930
AAV: Aave_0950
AMON: H9L24_09495
DLA: I6G47_27630
VAP: Vapar_1927
VPE: Varpa_4688
VPD: VAPA_1c53890
CTES: O987_08010
CSER: CCO03_06555
COF: FOZ74_09545
HYB: Q5W_21470
HYL: LPB072_07145
IDC: LRM40_05260
BBAY: A4V04_01330
PMOB: HG718_00085
BRK: CWS35_31850
BSEP: HAP48_0047655
BQB: J4P68_0006830
BAUT: QA635_15510
BBRA: QA636_16015
BPAH: QA639_29555
TALZ: RPMA_09995
BVES: QO058_11155
ANC: GBB76_09925
RCON: K3740_17735
SPOT: G6548_17115
SFAV: PL335_17210
THW: BMG03_04755
LVR: T8T21_17100
SPHO: C3E99_07010
SPLM: BXU08_19465
SSIN: G7078_06195
SPHL: LPB140_06435
ERR: DVR09_11395
DVN: HQ394_13385
THAI: IT893_15695
PAQI: KW060_14930
HEO: C694_03500
HPJ: jhp_0620
HPA: HPAG1_0661
HPS: HPSH_03470
HHP: HPSH112_03620
HHQ: HPSH169_03465
HHR: HPSH417_03260
HPG: HPG27_637
HPP: HPP12_0690(wbpB)
HPB: HELPY_0692
HPL: HPB8_881(wbpB)
HPC: HPPC_03400
HCA: HPPC18_03315
HPM: HPSJM_03455
HPE: HPELS_03135
HPO: HMPREF4655_20921
HPI: hp908_0688(wbpB)
HPQ: hp2017_0665(wbpB)
HPW: hp2018_0666(wbpB)
HPU: HPCU_03650
HEF: HPF16_0688(wbpB)
HPF: HPF30_0654(wbpB)
HEQ: HPF32_0643(wbpB)
HEX: HPF57_0700(wbpB)
HPT: HPSAT_03405
HPZ: HPKB_0669
HPV: HPV225_0684
HPX: HMPREF0462_0737
HEN: HPSNT_03505
HPH: HPLT_03380
HEG: HPGAM_03495
HPN: HPIN_03255
HEP: HPPN120_03320
HEU: HPPN135_03335
HES: HPSA_03225
HPYS: HPSA20_0708
HCN: HPB14_03300
HPD: KHP_0646(wbpB)
HEY: MWE_0830(wbpB)
HER: C695_03505
HEI: C730_03505
HPYA: HPAKL117_03210
HPYK: HPAKL86_04340
HPYO: HPOK113_0689(wbpB)
HPYL: HPOK310_0668(wbpB)
HPYB: HPOKI102_03625
HPYC: HPOKI112_03660
HPYD: HPOKI128_03220
HPYE: HPOKI154_03450
HPYF: HPOKI422_03630
HPYG: HPOKI673_03435
HPYH: HPOKI828_03435
HPYJ: HPOKI898_03630
HPYR: K747_07485
HPYI: K750_05685
HPYU: K751_03995
HPYM: K749_02110
HEM: K748_00585
HEB: U063_0983
HEZ: U064_0987
HHE: HH_1662(wbpB)
HAC: Hac_0861(wbpB)
HMS: HMU06630
HFE: HFELIS_04170
HBI: HBZC1_15200
HCE: HCW_05405
HCM: HCD_05220
HCP: HCN_0856(wbpB)
HCB: HCBAA847_1124(wbpB)
HHM: BN341_16330
HAD: CDV25_01305
HET: BBW65_01175
HCL: NCTC13205_00267(ycjS)
HSH: NHP194022_04680
HPUL: NCTC13154_00522(ycjS_1)
HAIL: ASB7_01280
WSU: WS2188(WBPB)
TDN: Suden_1422
SULG: FJR48_03715
SPAL: FM071_05905
SMAX: FJR03_06645
SAQT: GJV85_04705
CCO: CCC13826_0542
CBLA: CBLAS_0711
ABU: Abu_0662
ALAN: ALANTH_0830
ANT: Arnit_2570
AAQI: AAQM_2034
ASUI: ASUIS_2001
PACO: AACT_0950
AHS: AHALO_0814
HBV: ABIV_0864
SUN: SUN_0093
SINU: IMZ28_10360
GEB: GM18_1433
GLO: Glov_1510
TAMM: GEAMG1_2516(wbpB)
GER: KP004_12105
GNT: KP003_11600 KP003_17840
GPL: M1B72_07915
GSB: GSUB_15340
GHC: L9S41_10670
PEF: A7E78_01465
DOL: Dole_1819
PABO: BCY86_02080
BBAT: Bdt_1672
BBAC: EP01_04555
BDC: DOE51_07880
BREY: MNR06_04710
NCN: BZZ01_20160
DSW: QR90_12655
DEIN: DAAJ005_05030
DRD: LMT64_11840
DRB: N0D28_10075
TTH: TT_C0287(wbpB)
MRB: Mrub_0358
MRE: K649_01410
MTAI: Mtai_v1c25020
RUL: UC8_06010(wbpB_1) UC8_50390(wbpB_2)
LCRE: Pla8534_69440(wbpB)
AMOB: HG15A2_31400(wbpB)
PBS: Plabr_1624
PBAS: SMSP2_01883(wbpB)
ALUS: STSP2_02795(wbpB)
GEP: Q9293_00420
BUN: Bun01g_30810
PGI: PG_2119
PGN: PGN_0168(wbpB)
PGT: PGTDC60_1302
PEND: LA319_05660
PII: NF347_12995
OSP: Odosp_0961
BVIR: I6J59_09245 I6J59_14365
BFH: F1611_03130
TTZ: FHG85_08190
BLQ: L21SP5_01622(wbpB)
BACC: BRDCF_p620(ycjS) BRDCF_p621
DORI: FH5T_09010 FH5T_09100 FH5T_21445
DRC: G0Q07_02715
MCOS: GM418_12515 GM418_23735
FGG: FSB75_11455
HHY: Halhy_2761
ECHI: FKX85_20315
SPIB: G8759_15345
SOQ: LQ777_26125
SENF: GJR95_09775
RUN: DR864_23540
FPF: DCC35_01150
FKA: KM029_13880
FBT: D770_17610
CHRW: KA713_13995
CHK: D4L85_11150
FUV: JR347_14480
FBR: FBFL15_1030
ZGA: ZOBELLIA_1740(wbpB)
ZLA: Q5W13_08580
POM: MED152_05725
POB: LPB03_07140
PRN: BW723_09650
POLA: BXQ17_13895
POA: CW731_08025
PHAL: H9I45_06505
PLIT: K8354_09870
PPEC: H9W90_01185
PBAT: JL193_14510
PCEA: J3359_17210
PUN: NQP51_08280
PHG: KCTC32516_01449(wbpB)
TDI: AUW17_02345
TEN: LPB136_06615
TJE: TJEJU_1135(wbpB)
TMAR: MARIT_2536(wbpB)
TMP: F9Y86_04690
TOV: PG911_16305
TRT: PG912_10895
TFI: PJJ26_03005
TSIG: D6T69_05605
LUT: Lupro_06250
WFU: AXE80_01025
SALT: AO058_00385
AQB: D1818_09115
AQA: D1815_20985
EMAR: D1013_01180
PSYN: E9099_06905
MGEL: G5B37_01375
GAA: HX109_12625
ASAG: FGM00_16580
SPON: HME9304_01540(wbpB)
FBE: FF125_12120
LUY: QZH61_06860
SHYR: LA303_13210
RMR: Rmar_1674
RMG: Rhom172_1112
IAL: IALB_2460(wbpB)
MRO: MROS_2688
CPRV: CYPRO_3324
SAF: SULAZ_0344
CNI: Calni_1806
CABY: Cabys_972
 » show all
Reference
PMID:19348502
  Authors
Larkin A, Imperiali B
  Title
Biosynthesis of UDP-GlcNAc(3NAc)A by WbpB, WbpE, and WbpD: enzymes in the Wbp pathway responsible for O-antigen assembly in Pseudomonas aeruginosa PAO1.
  Journal
Biochemistry 48:5446-55 (2009)
DOI:10.1021/bi900186u
  Sequence
[pae:PA3158]
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