KEGG ORTHOLOGY: K13122

ORTHOLOGY: K13122

Entry

K13122                      KO

Symbol

FRG1

Name

protein FRG1

Disease

H00591

Facioscapulohumeral muscular dystrophy

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03041 Spliceosome
    K13122  FRG1; protein FRG1
Spliceosome [BR:ko03041]
Complex C
  Other components
   Complex C specific factors
    K13122  FRG1; protein FRG1

Genes

HSA:	2483(FRG1)

PTR:	100611163 107974518(FRG1)

PPS:	100991960(FRG1) 117974334 117977268

GGO:	101136513(FRG1) 101144369

NLE:	100580499(FRG1) 100585027 115834045

MCC:	114669716(FRG1) 698743(FRG1)

MCF:	102125123(FRG1)

MTHB:

126955462

MNI:	105466513(FRG1)

CSAB:

103236670(FRG1) 103247117

CATY:

105577161(FRG1)

PANU:

101012358(FRG1) 101014538 116273277

TGE:	112624699(FRG1) 112633337

MLEU:

105554724(FRG1)

RRO:	104653922(FRG1) 104660116

RBB:

108519868

TFN:	117086237(FRG1) 117095594

PTEH:

111528080(FRG1) 111552991

CANG:

105516961(FRG1)

CJC:	100402668(FRG1)

SBQ:	101046223(FRG1)

CIMI:

108294253(FRG1)

CSYR:

103250296 103275748

MMUR:

105882115(FRG1)

LCAT:

123638605(FRG1)

PCOQ:

105815247

OGA:	100952912(FRG1)

MMU:	14300(Frg1)

MCAL:

110300379(Frg1)

MPAH:

110336714(Frg1)

RNO:	686103(Frg1) 689484(Frg1l1)

MCOC:

116069199(Frg1)

ANU:	117716149 117721712(Frg1)

MUN:	110558779(Frg1)

CGE:	100770784(Frg1)

MAUA:

101841151(Frg1)

PROB:

127220453(Frg1)

PLEU:

114695134(Frg1)

MORG:

121433841(Frg1) 121442820

MFOT:

126504766

AAMP:

119813330(Frg1)

NGI:	103748257(Frg1)

HGL:	101724089(Frg1)

CPOC:

100717741(Frg1)

CCAN:

109692106(Frg1)

DORD:

105991356(Frg1)

DSP:	122126077(Frg1)

PLOP:

125339528(Frg1)

NCAR:

124984045

MMMA:

107142633(Frg1)

OCU:

100345738

OPI:	101531699(FRG1)

TUP:	102486445(FRG1)

GVR:	103590193(FRG1)

CFA:	100856082(FRG1)

CLUD:

112672128(FRG1)

VVP:	112908923 112934850(FRG1)

VLG:	121489220(FRG1)

NPO:	129515864(FRG1)

AML:	100471378(FRG1)

UMR:	103681348(FRG1)

UAH:	113262150(FRG1)

UAR:	123780431(FRG1)

ELK:

111144451

LLV:

125092248

MPUF:

101689131(FRG1)

MNP:	132006355(FRG1)

MLK:	131820376(FRG1)

NVS:	122889921(FRG1)

EJU:	114206125(FRG1)

ZCA:	113925028(FRG1)

MLX:	118010042(FRG1)

NSU:	110584179(FRG1)

LWW:	102749702(FRG1)

FCA:	101100298(FRG1)

PYU:	121012483 121039721(FRG1)

PCOO:

112869186 112869916

PBG:	122466959 122471176(FRG1)

PVIV:

125162439 125164458(FRG1)

LRUF:

124503713 124517592 124520449

PTG:	102969453(FRG1)

PPAD:

109277195(FRG1)

PUC:	125923439 125936303

AJU:	106988338 113602586

HHV:	120248094(FRG1)

BTA:	512533(FRG1)

BOM:	102285571(FRG1)

BIU:	109553325(FRG1)

BBUB:

102393372 102411501(FRG1)

BBIS:

105001913(FRG1)

CHX:	100861075(FRG1)

OAS:	101117645(FRG1)

BTAX:

128068310(FRG1)

ODA:	120865764(FRG1)

CCAD:

122432359(FRG1)

MBEZ:

129549336(FRG1) 129561141

SSC:	100515105(FRG1)

CFR:	102504216(FRG1)

CBAI:

105067661(FRG1)

CDK:	105102376(FRG1)

VPC:	102527098(FRG1)

BACU:

103003937(FRG1)

BMUS:

118888085(FRG1)

LVE:	103085032(FRG1)

OOR:	101276612(FRG1)

DLE:	111173435(FRG1)

PCAD:

102990966(FRG1)

PSIU:

116746720(FRG1)

NASI:

112409656(FRG1)

ECB:	100054569(FRG1)

EPZ:	103556310(FRG1)

EAI:	106828201(FRG1)

MYB:	102261655(FRG1)

MYD:	102767628(FRG1)

MMYO:

118650980(FRG1)

MLF:	102425450(FRG1)

PKL:	118730111(FRG1)

EFUS:

103290315(FRG1)

MNA:	107534039(FRG1)

DRO:	112306674(FRG1)

SHON:

118993099(FRG1)

AJM:	119036837(FRG1)

PDIC:

114508635(FRG1)

PHAS:

123807561(FRG1)

MMF:	118622654(FRG1)

PPAM:

129064695(FRG1)

HAI:	109394588(FRG1)

RFQ:	117021016(FRG1)

PALE:

102884250(FRG1)

PGIG:

120583820(FRG1)

PVP:	105295538(FRG1)

RAY:	107502660(FRG1)

MJV:	108384645(FRG1)

TOD:	119257926(FRG1)

SARA:

101555902(FRG1)

SETR:

126006866(FRG1)

LAV:	100672152(FRG1)

TMU:

101359126

ETF:	101659659(FRG1)

DNM:	101437502(FRG1)

MDO:	100013299(FRG1)

GAS:	123250976(FRG1)

SHR:	100924063(FRG1)

AFZ:

127539812

PCW:	110201239(FRG1)

OAA:	100086211(FRG1)

GGA:	422726(FRG1)

PCOC:

116225950(FRG1)

MGP:	100538472(FRG1)

CJO:	107313736(FRG1)

TPAI:

128080164(FRG1)

LMUT:

125691638(FRG1)

NMEL:

110397956(FRG1)

APLA:

101801920(FRG1)

ACYG:

106035213(FRG1)

CATA:

118245469(FRG1)

AFUL:

116489085(FRG1)

TGU:	100190404(FRG1)

LSR:	110474718(FRG1)

SCAN:

103825422(FRG1)

PMOA:

120498026(FRG1)

OTC:	121335214(FRG1)

PRUF:

121360340(FRG1)

GFR:	102045209(FRG1)

FAB:	101819421(FRG1)

OMA:	130252156(FRG1)

PHI:	102108616(FRG1)

PMAJ:

107203570(FRG1)

CCAE:

111943241(FRG1)

CCW:	104690595(FRG1)

CBRC:

103622567(FRG1)

ETL:	114064486(FRG1)

ZAB:	102065566(FRG1)

ACHL:

103804163(FRG1)

SVG:	106851505(FRG1)

MMEA:

130583161(FRG1)

HRT:	120753439(FRG1)

FPG:	101915754(FRG1)

FCH:	102059173(FRG1)

CLV:	102098395(FRG1)

EGZ:	104129487(FRG1)

NNI:	104020793(FRG1)

PCRI:

104029644(FRG1)

PLET:

104614825(FRG1)

EHS:	104503947(FRG1)

PCAO:

104053272(FRG1)

ACUN:

113479056(FRG1)

TALA:

104355591(FRG1)

PADL:

103926330(FRG1)

AFOR:

103897382(FRG1)

ACHC:

115343661(FRG1)

HALD:

104311097(FRG1)

HLE:	104833400(FRG1)

AGEN:

126037472

GCL:

127016016

CCRI:

104155659(FRG1)

CSTI:

104557089(FRG1)

CMAC:

104475945(FRG1)

MUI:	104540017(FRG1)

BREG:

104630081(FRG1)

FGA:	104077954(FRG1)

GSTE:

104251970(FRG1)

LDI:	104340959(FRG1)

MNB:	103775812(FRG1)

OHA:	104334941(FRG1)

NNT:	104407284(FRG1)

SHAB:

115610331(FRG1)

DPUB:

104304143(FRG1)

PGUU:

104459092(FRG1)

ACAR:

104518693(FRG1)

CPEA:

104393021(FRG1)

AVIT:

104271717(FRG1)

CVF:	104285449(FRG1)

RTD:	128910409(FRG1)

CUCA:

104067120(FRG1)

TEO:	104384354(FRG1)

BRHI:

104489138(FRG1)

AAM:	106490200(FRG1)

AROW:

112969368(FRG1)

NPD:	112942629(FRG1)

TGT:	104576705(FRG1)

DNE:	112985741(FRG1)

SCAM:

104138341(FRG1)

ASN:	102384243(FRG1)

AMJ:	102565111(FRG1)

CPOO:

109322234(FRG1)

GGN:	109304069(FRG1)

PSS:	102444932(FRG1)

CMY:	102946864(FRG1)

CCAY:

125635858(FRG1)

DCC:	119855033(FRG1)

CPIC:

101943971(FRG1)

TST:	117878286(FRG1)

CABI:

116835382(FRG1)

MRV:	120405915(FRG1)

ACS:	100558213(frg1)

ASAO:

132776682(FRG1)

PVT:	110077897(FRG1)

PBI:	103052683(FRG1)

PMUR:

107301642 107301654

CTIG:

120310689(FRG1)

TSR:

106537974

PGUT:

117680168(FRG1)

APRI:

131203215(FRG1)

PTEX:

113434656(FRG1)

NSS:	113411840(FRG1)

VKO:	123036402(FRG1)

PMUA:

114604528(FRG1)

PRAF:

128421519(FRG1)

ZVI:	118084475(FRG1)

HCG:	128337600(FRG1)

GJA:	107108736(FRG1)

STOW:

125439047 125439412

EMC:	129336748(FRG1)

XLA:	444679(frg1.L)

XTR:	448726(frg1)

NPR:	108785690(FRG1)

RTEM:

120921956(FRG1)

BBUF:

120991765(FRG1)

BGAR:

122940054(FRG1)

MUO:	115461564(FRG1)

GSH:	117360257(FRG1)

DRE:	550491(frg1)

SRX:	107721419 107747397

SANH:

107656998 107702291

SGH:	107554393 107562925(frg1)

CCAR:

109071934(frg1)

CAUA:

113080948 113107471

CGIB:

127968788

PTET:

122350064(frg1)

LROH:

127158127(frg1)

OMC:	131554055(frg1)

PPRM:

120488819(frg1)

RKG:	130089454(frg1)

MAMB:

125272546(frg1)

CIDE:

127495504

MASI:

127443573 127444534

TROS:

130552694(frg1)

TDW:	130434935(frg1)

MANU:

129444798(frg1)

IPU:	100528784(frg1)

IFU:	128604365(frg1)

PHYP:

113547381(frg1)

SMEO:

124381458(frg1)

TFD:	113635550(frg1)

TVC:	132841995(frg1)

AMEX:

103047182(frg1)

CMAO:

118816993(frg1)

EEE:	113591081(frg1)

CHAR:

105906982(frg1)

TRU:	445937(frg1)

TFS:	130527987(frg1)

TNG:	GSTEN00013710G001

LCO:	104917719(frg1)

NCC:	104943260(frg1)

TBEN:

117481535(frg1)

CGOB:

115008969(frg1)

PGEO:

117448286(frg1)

GACU:

117556236(frg1)

EMAC:

134864642(frg1)

ELY:	117254670(frg1)

EFO:	125885454(frg1)

PLEP:

121942340(frg1)

SLUC:

116034897(frg1)

ECRA:

117959850(frg1)

ESP:	116670164(frg1)

PFLV:

114561877(frg1)

GAT:	120824961(frg1)

PPUG:

119218535(frg1)

AFB:	129096093(frg1)

CLUM:

117737154(frg1)

PSWI:

130189960(frg1)

MSAM:

119898806(frg1)

SCHU:

122873700(frg1)

CUD:	121507997(frg1)

ALAT:

119029239(frg1)

MZE:	101476710(frg1)

ONL:	100694614(frg1)

OAU:	116334012(frg1)

OLA:	101161950(frg1)

OML:	112137241(frg1)

CSAI:

133441552(frg1)

XMA:	102231358(frg1)

XCO:	114144123(frg1)

XHE:	116719554(frg1)

PRET:

103461647(frg1)

PFOR:

103136380(frg1)

PLAI:

106944157(frg1)

PMEI:

106933340(frg1)

GAF:	122830132(frg1)

PPRL:

129376790(frg1)

CVG:	107090457(frg1)

CTUL:

119774321(frg1)

GMU:	124868756(frg1)

NFU:

107397242

KMR:	108234435(frg1)

ALIM:

106525836(frg1)

NWH:	119423057(frg1)

AOCE:

111580239(frg1)

MCEP:

125001300(frg1)

CSEM:

103384333(frg1)

POV:	109639571(frg1)

SSEN:

122770483(frg1)

HHIP:

117770492(frg1)

HSP:	118116661(frg1)

SMAU:

118312767(frg1)

LCF:	108893119 108902600

SDU:	111216677(frg1)

SLAL:

111663284(frg1)

XGL:	120800267(frg1)

HCQ:	109511170(frg1)

SSCV:

125969330

SBIA:

133506618(frg1)

PEE:	133404462(frg1)

PTAO:

133476739(frg1)

BPEC:

110167610(frg1)

MALB:

109972129(frg1)

BSPL:

114860860(frg1)

SJO:	128380765(frg1)

SASA:

100286478(frg1) 106609940

STRU:

115191911 115202130

OTW:	112231801 112261390

OMY:	110497463 110534408

OGO:	124002213(frg1) 124012347

ONE:	115137320 115145864

OKI:	109894164 109901127

OKE:

118362953

SALP:

111958507 111971577

SNH:	120035145 120052866

CCLU:

121550758 123485573 123487892

ELS:	105022855(frg1)

SFM:	108924405(frg1)

PKI:	111853583(frg1)

AANG:

118228466(frg1)

LOC:	102683919(frg1)

PSPA:

121328161(frg1)

ARUT:

117408600(frg1)

PSEX:

120527490(frg1)

LCM:	102355867(FRG1)

CMK:	103178196(frg1)

RTP:	109929942(frg1)

CPLA:

122549820(frg1)

HOC:	132819122(frg1)

LERI:

129697073(frg1)

PMRN:

116940409(FRG1)

LRJ:	133343291(FRG1)

BFO:

BBEL:

CIN:

SCLV:

SPU:	577693 589065

LPIC:

APLC:

AJC:

SKO:

DME:	Dmel_CG6480(FRG1)

DER:

6544737

DSI:	Dsimw501_GD12203(Dsim_GD12203)

DYA:	Dyak_GE22419 Dyak_GE22421

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI11833

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:	108369069 108378119

AOQ:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

CQU:	CpipJ_CPIJ013211

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:	122498840 122498841

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_215571

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:

PGW:

CFEL:

CCRN:

API:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

HVI:

MQU:

PHU:	Phum_PHUM599650

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_303869

DMK:

116936470

DPZ:	124313296 124343762

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:	135202184 135202185

HAZT:

EAF:

LSM:

TCF:

PPOI:

DSV:	119444691 119449441

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

CEL:	CELE_ZK1010.3(frg-1)

CBR:	CBG_15774(Cbr-frg-1)

CRQ:	GCK72_010951

NAI:	NECAME_15082

BMY:	BM_BM7607(Bma-frg-1)

LOA:	LOAG_10231

TSP:

Tsp_01655

HRO:	HELRODRAFT_110978

LGI:	LOTGIDRAFT_104723

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CVN:

CANU:

OED:

MYI:

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

OBI:

OSN:	115219812 118768638

LAK:	106161937 106169436

SMM:	Smp_037290

SHX:	MS3_00002339(FRG1_1)

OVI:	T265_01462

EGL:

NVE:

EPA:

ATEN:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

TAD:	TRIADDRAFT_56229

AQU:

100638800

DHA:	DEHA2D03850g

YLI:	YALI0F02761g

SLB:	AWJ20_1580

OPA:	HPODL_00188

NCR:

NCU02559

NTE:	NEUTE1DRAFT126495(NEUTE1DRAFT_126495)

SMP:	SMAC_05801

PAN:	PODANSg09930

PBEL:

PPSD:

PPSP:

PPSA:

TTT:	THITE_2122080

MTM:	MYCTH_2295243

CTHR:

MGR:

PPEI:

PGRI:

TMN:	UCRPA7_3764

SSCK:

SPSK_05484

FGR:	FGSG_09305

FPU:	FPSE_09711

FPOA:

FPOAC1_012379

FVN:	FVRRES_13458

FVR:	FVEG_03784

FOX:	FOXG_05913

NHE:	NECHADRAFT_75536

FFC:	NCS54_00170500

FKR:	NCS57_00168200

FMU:	J7337_003792

TRE:	TRIREDRAFT_64794

TRR:	M419DRAFT_83087

MAW:

MAJ:

PCHM:

CMT:

AMUS:

PLJ:	VFPFJ_10062

PTKZ:

JDV02_008978

VAL:	VDBG_03732

VDA:	VDAG_00964

CFJ:	CFIO01_10850

CLUP:

CLUP02_13651

CHIG:

CH63R_05753

SAPO:

SAPIO_CDS5554

ELA:	UCREL1_1279

PFY:	PFICI_02704

SSL:	SS1G_05777

BFU:	BCIN_05g01680

MBE:

MBM_09747

PSCO:

LY89DRAFT_788716

GLZ:	GLAREA_03785

ANI:	ANIA_00442

AFM:	AFUA_1G04610

ACT:	ACLA_030050

NFI:	NFIA_020130

AOR:	AO090003000887

ANG:	An01g03490

AFV:	AFLA_000789

ALUC:

AKAW2_20516S

ACHE:

ACHE_11637S

APUU:

APUU_11614S

PCS:	N7525_010897

PDP:	PDIP_21150

POU:	POX_e06933

TMF:	EYB26_008248

TRG:	TRUGW13939_00500

CIM:	CIMG_04944

CPW:	CPC735_069360

URE:	UREG_06607

PBL:	PAAG_00964

PBN:	PADG_03860

ABE:

ARB_06172

TVE:

TRV_00618

AJE:	HCAG_03604

BGH:	BDBG_05374

PNO:	SNOG_11411

PTE:

PTT_12714

BZE:	COCCADRAFT_38723

BSC:	COCSADRAFT_30375

BOR:	COCMIDRAFT_24322

AALT:

CC77DRAFT_801712

ARAB:

EKO05_0003560

ZTR:	MYCGRDRAFT_65433

PFJ:	MYCFIDRAFT_38875

FFU:	CLAFUR5_11709

CBET:

CB0940_11877

BCOM:

BAUCODRAFT_65561

NPA:	UCRNP2_3577

TML:	GSTUM_00004272001

SPO:	SPBP23A10.12(frg1)

SOM:	SOMG_01605(frg1)

CNE:

CNL06250

CNB:

CNBI0570

CNG:	CNAG_04989

CGI:	CGB_D0500W

CDEU:

CNBG_4690

TMS:	TREMEDRAFT_71166

TASA:

A1Q1_02652

CCAC:

CcaHIS019_0201690(CcaverHIS019_0201690)

TVS:	TRAVEDRAFT_145823

DSQ:	DICSQDRAFT_77617

PCO:	PHACADRAFT_28406

SHS:	STEHIDRAFT_33730

HIR:	HETIRDRAFT_32020

PSQ:	PUNSTDRAFT_114726

ADL:	AURDEDRAFT_18915 AURDEDRAFT_28969

FME:	FOMMEDRAFT_147388

GTR:	GLOTRDRAFT_72685

RSX:	RhiXN_01869

LBC:	LACBIDRAFT_306146

CCI:	CC1G_13879

ABP:	AGABI1DRAFT111137(AGABI1DRAFT_111137)

ABV:	AGABI2DRAFT63922(AGABI2DRAFT_63922)

MRR:	Moror_7955

E1B28_008932

SCM:	SCHCO_01119233(SCHCODRAFT_01119233)

CPUT:

CONPUDRAFT_87579

SLA:	SERLADRAFT_480985

WSE:	WALSEDRAFT_14949

WIC:	J056_002060

UMA:	UMAG_00929

PFP:	PFL1_02775

SGRA:

MGL:

MRT:

MSYM:

PGR:	PGTG_15794

PTRC:

PtA15_17A25 PtA15_18A350

PSTR:

Pst134EA_030197

MLR:	MELLADRAFT_76080

MBR:	MONBRDRAFT_15040

SRE:	PTSG_01137

» show all

Reference

PMID:16341202

Authors

Gabellini D, D'Antona G, Moggio M, Prelle A, Zecca C, Adami R, Angeletti B, Ciscato P, Pellegrino MA, Bottinelli R, Green MR, Tupler R

Title

Facioscapulohumeral muscular dystrophy in mice overexpressing FRG1.

Journal

Nature 439:973-7 (2006)
DOI:10.1038/nature04422

Sequence

[hsa:2483] [mmu:14300]

Reference

PMID:23720823

Authors

Neguembor MV, Xynos A, Onorati MC, Caccia R, Bortolanza S, Godio C, Pistoni M, Corona DF, Schotta G, Gabellini D

Title

FSHD muscular dystrophy region gene 1 binds Suv4-20h1 histone methyltransferase and impairs myogenesis.

Journal

J Mol Cell Biol 5:294-307 (2013)
DOI:10.1093/jmcb/mjt018

Sequence

[dme:Dmel_CG6480]

LinkDB

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