KEGG ORTHOLOGY: K13209

ORTHOLOGY: K13209

Entry

K13209                      KO

Symbol

EWSR1

Name

RNA-binding protein EWS

Pathway

map05202

Transcriptional misregulation in cancer

Disease

H00035

Ewing sarcoma

Brite

KEGG Orthology (KO) [BR:ko00001]
09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    K13209  EWSR1; RNA-binding protein EWS
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03041 Spliceosome
    K13209  EWSR1; RNA-binding protein EWS
   03036 Chromosome and associated proteins
    K13209  EWSR1; RNA-binding protein EWS
Spliceosome [BR:ko03041]
Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    K13209  EWSR1; RNA-binding protein EWS
Chromosome and associated proteins [BR:ko03036]
Eukaryotic type
  Meiosis-specific proteins
   DSB formation-related proteins
    K13209  EWSR1; RNA-binding protein EWS

Genes

HSA:	2130(EWSR1)

PTR:	748264(EWSR1)

PPS:	100993328(EWSR1)

GGO:	101126077(EWSR1)

PON:	100173925(EWSR1)

PPYG:

129023475(EWSR1)

NLE:	100595788(EWSR1)

HMH:	116459461(EWSR1)

SSYN:

129468604(EWSR1)

MCC:	714432(EWSR1)

MCF:	102116857(EWSR1)

MTHB:

126963964

MNI:	105487270(EWSR1)

CSAB:

103223132(EWSR1)

CATY:

105575691(EWSR1)

PANU:

101021166(EWSR1)

TGE:	112632952(EWSR1)

MLEU:

105550726(EWSR1)

RRO:	104659113(EWSR1)

RBB:	108517544(EWSR1)

TFN:	117096144(EWSR1)

PTEH:

111525363(EWSR1)

CANG:

105506610(EWSR1)

CJC:	100409195(EWSR1) 100895215 118143622

SBQ:	101048688(EWSR1)

CIMI:

108283249(EWSR1) 108294231 108294819

ANAN:

105725792(EWSR1) 110567433

CSYR:

103253609 103273585(EWSR1)

MMUR:

105870901(EWSR1) 105872827

LCAT:

123625806(EWSR1) 123644670

PCOQ:

105810189(EWSR1)

OGA:	100946202(EWSR1)

MMU:	14030(Ewsr1)

MCAL:

110305041(Ewsr1)

MPAH:

110330791(Ewsr1)

RNO:	289752(Ewsr1)

MCOC:

116069338(Ewsr1) 116071141

ANU:	117712616(Ewsr1)

ASYL:

127695930(Ewsr1)

MUN:	110546102(Ewsr1)

CGE:	100773033(Ewsr1)

MAUA:

101829351 101839906(Ewsr1)

PROB:

127233712(Ewsr1)

PLEU:

114693993(Ewsr1)

MORG:

121436403(Ewsr1) 121459283

MFOT:

126500998

AAMP:

119800806 119807266 119818611(Ewsr1) 119821150

NGI:	103740474(Ewsr1)

HGL:	101697325(Ewsr1)

CPOC:

100718262(Ewsr1)

CCAN:

109682513(Ewsr1) 109702440

DORD:

105984266(Ewsr1)

DSP:	122097181(Ewsr1)

PLOP:

125349252(Ewsr1)

NCAR:

124971883 124991512

MMMA:

107154586(Ewsr1)

ITI:	101963268(Ewsr1) 101968608

OCU:	100343577 100355330 100356663

OPI:	101516128(EWSR1)

TUP:	102489465(EWSR1)

GVR:	103588200(EWSR1)

CFA:	609786(EWSR1)

CLUD:

112648195 112649506 112668066 112676776(EWSR1)

VVP:	112906908(EWSR1) 112915057 112927559

VLG:	121475398(EWSR1)

NPO:	129507869(EWSR1) 129518647

AML:	100466147(EWSR1)

UMR:	103658915 103659242(EWSR1)

UAH:	113245008(EWSR1) 113261851

UAR:	123788142(EWSR1) 123789148

ELK:

111160077

LLV:	125081303 125091611 125097492 125103085 125108543

MPUF:

101685938(EWSR1)

MNP:	132018087 132024782

MLK:	131811701(EWSR1) 131824878 131826680

NVS:	122903284(EWSR1) 122906535 122915680

ORO:	101382318(EWSR1) 101383144

EJU:	114225154(EWSR1)

ZCA:	113912747(EWSR1)

MLX:	118000440 118002838 118018623(EWSR1)

NSU:	110572167 110591195 110592497(EWSR1)

LWW:

102747029

FCA:	101093398(EWSR1)

PYU:	121013348 121022565(EWSR1)

PCOO:

112870231(EWSR1)

PBG:	122470420(EWSR1)

PVIV:

125149618(EWSR1)

LRUF:

124518150

LGF:	123588161(EWSR1)

AJU:

106985454

PTG:	102961391(EWSR1)

PPAD:

109253554(EWSR1)

PUC:

125913938

PLEZ:

122203064(EWSR1)

HHV:	120227857(EWSR1)

BTA:	534073(EWSR1)

BOM:	102268101(EWSR1)

BIU:	109571086(EWSR1)

BBUB:

102394434 102399452 102405454(EWSR1) 112583627

CHX:	102185022(EWSR1)

OAS:	101121203(EWSR1)

BTAX:

128062187(EWSR1)

CSUM:

138093928(EWSR1)

ODA:	120871469(EWSR1) 120879561

CCAD:

122421393(EWSR1) 122432738

MREE:

136146015(EWSR1)

OVR:	110146349(EWSR1)

MBEZ:

129542790(EWSR1)

SSC:	100156911(EWSR1)

CFR:	102507824(EWSR1)

CBAI:

105066052(EWSR1)

CDK:	105099468(EWSR1)

VPC:	102526839(EWSR1)

BACU:

103011588(EWSR1)

BMUS:

118906692(EWSR1)

LVE:	103081334(EWSR1)

OOR:	101277797(EWSR1) 101288016

LALB:

132504440(EWSR1) 132511241

DLE:	111162822(EWSR1)

PCAD:

102995796

PSIU:

116765075(EWSR1)

NASI:

112415122(EWSR1)

ECB:	100034010(EWSR1)

EPZ:	103548100(EWSR1)

EAI:	106827452(EWSR1)

MYB:	102251421(EWSR1)

MYD:	102754178 102765499(EWSR1)

MMYO:

118659169 118678455(EWSR1)

MLF:	102427672(EWSR1)

MDT:	132221782(EWSR1) 132235437

MYUM:

138997817(EWSR1)

PKL:	118725343(EWSR1) 118726400

EFUS:

103286869(EWSR1)

MNA:	107526203(EWSR1)

DRO:	112310329(EWSR1)

SHON:

118987810 118991261(EWSR1)

AJM:	119055176(EWSR1)

PDIC:

114509230(EWSR1)

PHAS:

123810776(EWSR1)

MMF:	118639850(EWSR1)

PPAM:

129065573 129073226 129078113 129087299(EWSR1)

HAI:	109383058(EWSR1)

RFQ:	117016864 117017242(EWSR1)

PALE:

102884203(EWSR1)

PGIG:

120601952(EWSR1)

PVP:	105300934(EWSR1)

RAY:	107520476(EWSR1)

MJV:	108402485(EWSR1)

TOD:	119244815(EWSR1)

SARA:

101553452(EWSR1)

SFUM:

130018335 130025702(EWSR1)

SETR:

126030736(EWSR1)

LAV:	100664498(EWSR1)

TMU:

101352929

ETF:	101646114(EWSR1)

DNM:	101424032(EWSR1)

MDO:	100018014(EWSR1)

GAS:	123244957 123255557 123256929(EWSR1)

SHR:	100930766(EWSR1)

AFZ:

127545645

PCW:	110215138(EWSR1)

TVP:	118846628(EWSR1)

PBRV:

138142821 138156323(EWSR1)

OAA:	100086321(EWSR1)

TACU:

119942923(EWSR1)

GGA:	417022(EWSR1)

PCOC:

116228345(EWSR1)

MGP:	100550662(EWSR1)

CJO:	107321343(EWSR1)

TPAI:

128083981(EWSR1)

LMUT:

125701738(EWSR1)

NMEL:

110406187

APLA:

101789800(EWSR1)

ACYG:

106045524(EWSR1)

CATA:

118252943(EWSR1)

AFUL:

116496103(EWSR1)

TGU:	100218670(EWSR1)

LSR:	110474149(EWSR1)

SCAN:

103818224(EWSR1)

PMOA:

120510212(EWSR1)

OTC:	121344454(EWSR1)

PRUF:

121365094(EWSR1)

ATRC:

139598854(EWSR1)

GFR:	102040753(EWSR1)

FAB:	101814762(EWSR1)

OMA:	130259741(EWSR1)

PHI:	102108027(EWSR1)

PMAJ:

107211577(EWSR1)

CCAE:

111936769(EWSR1)

CCW:	104695034(EWSR1)

CBRC:

103623803(EWSR1)

ACOE:

138119023(EWSR1)

ETL:	114071710(EWSR1)

ZAB:

102074691

ZLE:	135454536(EWSR1)

ACHL:

103802857(EWSR1)

SVG:	106864789(EWSR1)

MMEA:

130585092(EWSR1)

SATI:

136368778(EWSR1)

CCIC:

134050742(EWSR1)

FPG:	101923346(EWSR1)

FCH:	102053431(EWSR1)

CCRI:

104159609(EWSR1)

NNT:	104412646(EWSR1)

SHAB:

115614085(EWSR1)

ACUN:

113486180(EWSR1)

TALA:

104369178(EWSR1)

ACHC:

115345526(EWSR1)

HALD:

104311670

HLE:	104829239(EWSR1)

AGEN:

126040522

HHAR:

128145656(EWSR1)

GCL:

127022701

MNB:	103777623(EWSR1)

DPUB:

104308561(EWSR1)

PPUS:

135189013(EWSR1)

EGZ:	104129927(EWSR1)

NNI:	104010583(EWSR1)

PCRI:

104034432(EWSR1)

PCAO:

104041006(EWSR1)

PADL:

103916422(EWSR1)

AFOR:

103896502(EWSR1)

FGA:	104080209(EWSR1)

CLV:	102083728(EWSR1)

MUI:	104539901(EWSR1)

PGUU:

104467746(EWSR1)

PLET:

104622005(EWSR1)

CMAC:

104486216

CUCA:

104056150(EWSR1)

TEO:	104372092(EWSR1)

BREG:

104638442(EWSR1)

OHA:	104331303(EWSR1)

CPEA:

104388931(EWSR1)

CVF:	104281932(EWSR1)

RTD:	128917015(EWSR1)

CRID:

134522737(EWSR1)

AAM:	106497471(EWSR1)

AROW:

112976780(EWSR1)

NPD:	112950372(EWSR1)

TGT:

104575523

DNE:	112994662(EWSR1)

SCAM:

104149018

ASN:	102385989(EWSR1)

AMJ:	102561474(EWSR1)

CPOO:

109313022(EWSR1)

GGN:	109290289(EWSR1)

PSS:	102460772(EWSR1)

CMY:	102932099(EWSR1)

CCAY:

125622758(EWSR1)

DCC:	119843582(EWSR1)

CPIC:

101950083(EWSR1)

TST:	117888360(EWSR1)

CABI:

116815895(EWSR1)

MRV:	120386031(EWSR1)

ACS:	100557388(ewsr1)

ASAO:

132781222(EWSR1)

PVT:	110082908(EWSR1)

SUND:

121916692(EWSR1)

PBI:	103061398(EWSR1)

PMUR:

107288782(EWSR1)

CTIG:

120303299(EWSR1)

TSR:	106538565(EWSR1)

PGUT:

117672159(EWSR1)

APRI:

131185526(EWSR1)

NSS:	113426713(EWSR1)

VKO:	123032788(EWSR1)

PMUA:

114587114(EWSR1)

PRAF:

128403544(EWSR1)

ZVI:	118075756(EWSR1)

HCG:	128337828(EWSR1)

GJA:	107105977(EWSR1)

STOW:

125442528(EWSR1)

EMC:	129341168(EWSR1)

XLA:	398367 734969(ewsr1.L)

XTR:	394931(ewsr1)

NPR:	108798443(EWSR1)

RTEM:

120924573 120939132(EWSR1)

BBUF:

120988897(EWSR1)

BGAR:

122924323(EWSR1)

PWL:	138266139(EWSR1)

MUO:	115479898(EWSR1)

GSH:	117365902(EWSR1)

DRE:	322880(ewsr1b) 323597(ewsr1a)

SRX:	107713357 107730715 107744107 107744436

SANH:

107672746 107673396 107686447 107688168

SGH:	107562585 107569394 107592307 107599962

CCAR:

109061523 109061552(ewsr1a) 109089972 109090811(ewsr1b)

CAUA:

113049869 113054124 113091401 113110392

CGIB:

127957467 127966283 128011140 128021381

PTET:

122340933(ewsr1a) 122345494(ewsr1b)

LROH:

127165459(ewsr1b) 127171906(ewsr1a)

OMC:	131540075(ewsr1b) 131548334(ewsr1a)

PPRM:

120469535(ewsr1b) 120481688(ewsr1a)

RKG:	130078509(ewsr1b) 130087116(ewsr1a)

MAMB:

125256453(ewsr1a) 125266650(ewsr1b)

CIDE:

127512047 127520146

CERY:

137028853(ewsr1a) 137034403(ewsr1b)

MASI:

127421090 127432797 127433604 127439960

TROS:

130546254(ewsr1a) 130548106(ewsr1b)

TDW:	130411985(ewsr1a) 130419844(ewsr1b)

MANU:

129440021(ewsr1b) 129447213(ewsr1a)

PDAB:

135732397(ewsr1b) 135779627(ewsr1a)

IPU:	108255470(ewsr1b) 108277013(ewsr1a)

IFU:	128619998(ewsr1a) 128625416(ewsr1b)

PHYP:

113536835 113543933(ewsr1)

SMEO:

124380573(ewsr1b) 124393504(ewsr1a)

TFD:	113657401(ewsr1b) 113661307(ewsr1a)

TVC:	132854956(ewsr1b) 132862982(ewsr1a)

CGAR:

128509261(ewsr1b) 128545643(ewsr1a)

NGRA:

132872613(ewsr1b) 132873552(ewsr1a)

TRN:	134332779(ewsr1a) 134335101(ewsr1b)

AMEX:

103029174(ewsr1b) 103041658(ewsr1a)

CMAO:

118824616(ewsr1a) 118826851(ewsr1b)

EEE:	113574982 113583002

CHAR:

105895545(ewsr1a)

SPIL:

134060426(ewsr1a)

TRU:	101072585(ewsr1)

TFS:	130525597(ewsr1b)

TNG:	GSTEN00029479G001

LCO:	104920325(ewsr1)

NCC:	104965797(ewsr1)

TBEN:

117496791(ewsr1b)

CGOB:

115013327(ewsr1)

PGEO:

117452080(ewsr1b)

GACU:

117561083(ewsr1b)

EMAC:

134873431(ewsr1b)

ELY:	117252410(ewsr1b)

EFO:	125889651(ewsr1b)

PLEP:

121944531(ewsr1b)

SLUC:

116056607(ewsr1b)

ECRA:

117944760

ESP:	116688930(ewsr1)

PFLV:

114555499(ewsr1)

GAT:	120831226(ewsr1b)

PPUG:

119224505(ewsr1b)

AFB:	129101088(ewsr1b)

CLUM:

117736097

PSWI:

130196215

CANA:

137805110(ewsr1b)

CVE:

137866881

MSAM:

119884184

SCHU:

122876828(ewsr1b)

CUD:	121509267(ewsr1b)

SPUL:

138609902(ewsr1b)

LMIX:

132974918

ALAT:

119019524(ewsr1b)

ASTR:

137592386(ewsr1b)

MZE:	101470675(ewsr1)

ONL:	100703828(ewsr1)

OAU:	116332501(ewsr1b)

OLA:	101163744(ewsr1)

OML:	112148175(ewsr1b)

CSAI:

133450496(ewsr1b)

XMA:	102216719(ewsr1)

XCO:	114154352(ewsr1)

XHE:	116729458(ewsr1)

PRET:

103470295(ewsr1)

PFOR:

103142847(ewsr1)

PLAI:

106937079(ewsr1)

PMEI:

106918009(ewsr1)

GAF:	122828309(ewsr1b)

PPRL:

129372012(ewsr1b)

CVG:	107102369(ewsr1)

CTUL:

119790174(ewsr1b)

GMU:	124877781(ewsr1b)

NFU:	107394201(ewsr1)

KMR:	108234575(ewsr1b)

ALIM:

106521669(ewsr1)

NWH:

119413961

AOCE:

111575824(ewsr1b)

EJA:

138215840

BFRE:

138627196(ewsr1b)

MCEP:

125012143(ewsr1b)

CSEM:

103397238 103398620(ewsr1)

POV:	109638179(ewsr1)

SSEN:

122770097(ewsr1b)

SSOE:

131463563(ewsr1b)

HHIP:

117767424(ewsr1b)

HSP:	118115034(ewsr1b)

PPLT:

128438098(ewsr1b)

SMAU:

118313744(ewsr1b)

LCF:	108878220(ewsr1b)

SDU:	111228426(ewsr1)

SLAL:

111660268(ewsr1)

XGL:

120805734

HCQ:	109510591(ewsr1)

SSCV:

125965870

SBIA:

133499857(ewsr1b)

PEE:

133399765

PTAO:

133475490(ewsr1b)

BPEC:

110172434(ewsr1)

ENY:	140346589(ewsr1b)

MALB:

109961573(ewsr1)

BSPL:

114862183(ewsr1b)

SJO:	128364510(ewsr1b)

SSCO:

133979717(ewsr1b)

GMH:	115545905(ewsr1)

SASA:

106563186 106580328 106584976

STRU:

115164443 115200196 115204196

OTW:	112231101(ewsr1a) 112248523(ewsr1b) 112248525

OMY:	110509908(ewsr1a) 110525724 110536095

OGO:	124006984(ewsr1a) 124034271 124036364

ONE:	115101271 115111654 115140105

OKI:	109873781 109880418 109895950

OKE:	118358394 118385188(ewsr1a) 118393261

OMM:	135514036 135542193 135544363(ewsr1a)

OCLA:

139388285 139389372 139410963

SALP:

111958207 111964120 111974334

SNH:	120021316(ewsr1a) 120025316 120063009

CCLU:

121530965 121541776 121582394 121584897

ELS:	105014859 105026998(ewsr1)

OEP:	134012139(ewsr1b)

SFM:	108932569(ewsr1)

PKI:	111839952(ewsr1) 111851476

AANG:

118207013(ewsr1b) 118212731

AROT:

135239040 135264701(ewsr1b)

CCOG:

133140745 133142295(ewsr1a)

LOC:	102684567(ewsr1)

PSPA:

121296875 121299896

ARUT:

117426682 117427975

PSEX:

120539629(ewsr1a)

LCM:	102362097(EWSR1)

CMK:

RTP:

CPLA:

HOC:

LERI:

BBEL:

AJJ:

DMK:

HAME:

PTRU:

LSM:	121125712(caz)

DSV:

RSAN:

RMP:

DPTE:

DFR:

SDM:

HRO:	HELRODRAFT_189823

EGL:

EGR_00721

SMO:	SELMODRAFT_444235

UMA:	UMAG_02472

» show all

Reference

PMID:16202544

Authors

Janknecht R

Title

EWS-ETS oncoproteins: the linchpins of Ewing tumors.

Journal

Gene 363:1-14 (2005)
DOI:10.1016/j.gene.2005.08.007

Reference

PMID:1522903

Authors

Delattre O, Zucman J, Plougastel B, Desmaze C, Melot T, Peter M, Kovar H, Joubert I, de Jong P, Rouleau G, et al.

Title

Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours.

Journal

Nature 359:162-5 (1992)
DOI:10.1038/359162a0

Sequence

[hsa:2130]

LinkDB

DBGET integrated database retrieval system