KEGG ORTHOLOGY: K13220

ORTHOLOGY: K13220

Entry

K13220                      KO

Symbol

WBP4, FBP21

Name

WW domain-binding protein 4

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03041 Spliceosome
    K13220  WBP4, FBP21; WW domain-binding protein 4
Spliceosome [BR:ko03041]
Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    K13220  WBP4, FBP21; WW domain-binding protein 4

Genes

HSA:	11193(WBP4)

PTR:	452706(WBP4)

PPS:	100983126(WBP4)

GGO:	101153908(WBP4)

PON:	100431811(WBP4)

NLE:	100607370(WBP4)

HMH:	116467200(WBP4)

MCC:	698220(WBP4)

MCF:	102126338(WBP4)

MTHB:

126940340

MNI:	105491739(WBP4)

CSAB:

103214327(WBP4)

CATY:

105587828(WBP4)

PANU:

101020544(WBP4)

TGE:	112610713(WBP4)

MLEU:

105546925(WBP4)

RRO:	104671101(WBP4)

RBB:	108514127(WBP4)

TFN:	117096936(WBP4)

PTEH:

111540517(WBP4)

CANG:

105512512(WBP4)

CJC:	100415357(WBP4)

SBQ:	101052378(WBP4)

CIMI:

108286143(WBP4)

CSYR:

103274457(WBP4)

MMUR:

105871584(WBP4)

LCAT:

123648883(WBP4)

OGA:	100955545(WBP4)

MMU:	22380(Wbp4)

MCAL:

110309127(Wbp4)

MPAH:

110325126(Wbp4)

RNO:	114765(Wbp4)

MCOC:

116085166(Wbp4)

ANU:	117705058(Wbp4)

MUN:	110551916(Wbp4)

CGE:	100752786(Wbp4)

MAUA:

101827320(Wbp4)

PROB:

127230151(Wbp4)

PLEU:

114699593(Wbp4)

MORG:

121460300(Wbp4)

AAMP:

119800217(Wbp4) 119802997

NGI:	103751301(Wbp4)

HGL:	101702155(Wbp4)

CPOC:

100729950(Wbp4)

CCAN:

109691670(Wbp4)

DORD:

105981350(Wbp4)

DSP:	122112744(Wbp4)

PLOP:

125348224(Wbp4)

MMMA:

107141078(Wbp4)

OCU:

100354029

OPI:	101519230(WBP4)

TUP:	102500475(WBP4)

GVR:	103601532(WBP4)

CFA:	476935(WBP4)

CLUD:

112678818(WBP4)

VVP:	112928068(WBP4)

VLG:	121476956(WBP4)

NPO:	129516370(WBP4)

AML:	100478813(WBP4)

UMR:	103677552(WBP4)

UAH:	113251383(WBP4)

UAR:	123801105(WBP4)

ELK:

111147129

LLV:

125094657

MPUF:

101690955(WBP4)

MNP:	132002867(WBP4)

MLK:	131814012(WBP4)

NVS:	122907129(WBP4)

ORO:	101381579(WBP4)

EJU:	114212472(WBP4)

ZCA:	113919368(WBP4)

MLX:	118009375(WBP4)

NSU:	110587709(WBP4)

LWW:	102727730(WBP4)

FCA:	101091075(WBP4)

PYU:	121013028(WBP4)

PCOO:

112861049(WBP4)

PBG:	122483216(WBP4)

PVIV:

125171162(WBP4)

LRUF:

124512854

PTG:	102951393(WBP4)

PPAD:

109265867(WBP4)

PUC:

125933828

AJU:

106987215

HHV:	120245924(WBP4)

BTA:	506275(WBP4)

BOM:	102282620(WBP4)

BIU:	109566975(WBP4)

BBUB:

102398357(WBP4)

BBIS:

104993068(WBP4)

CHX:	102173201(WBP4)

OAS:	101107108(WBP4)

BTAX:

128057706(WBP4)

ODA:	120883171(WBP4)

CCAD:

122438599 122447049(WBP4)

MBEZ:

129556217(WBP4)

SSC:	110255820(WBP4)

CFR:	102512245(WBP4)

CBAI:

105083446(WBP4)

CDK:	105098503(WBP4)

VPC:	102537687(WBP4)

BACU:

103020352(WBP4)

BMUS:

118884018(WBP4)

LVE:	103076514(WBP4)

OOR:	101282161(WBP4)

DLE:	111170083 111175369(WBP4)

PCAD:

102979273 102984336(WBP4)

PSIU:

116742898(WBP4) 116744014

NASI:

112396941 112413516(WBP4)

ECB:	100147547(WBP4)

EPZ:	103560279(WBP4)

EAI:	106839859(WBP4)

MYB:	102252834(WBP4)

MYD:	102751480(WBP4)

MMYO:

118650276(WBP4)

MLF:	102422634(WBP4)

PKL:	118730808(WBP4)

EFUS:

114232963(WBP4)

MNA:	107531371(WBP4)

DRO:	112312692(WBP4)

SHON:

118996876(WBP4)

AJM:	119046289(WBP4)

PDIC:

114508558(WBP4)

PHAS:

123818765(WBP4)

MMF:	118622895(WBP4)

PPAM:

129080895(WBP4)

HAI:	109386852(WBP4)

RFQ:	117021716(WBP4)

PALE:

102881292(WBP4)

PGIG:

120614365(WBP4)

PVP:	105298458(WBP4)

RAY:	107517447(WBP4)

MJV:	108393426(WBP4)

TOD:	119258709(WBP4)

SARA:

101555090(WBP4)

SETR:

126016241(WBP4)

LAV:	100657732(WBP4)

TMU:

101352626

ETF:	123521352(WBP4)

DNM:	101430251(WBP4)

MDO:	100014190(WBP4)

GAS:	123242678(WBP4) 123253465

SHR:	100919062(WBP4)

AFZ:

127553279

PCW:	110201408(WBP4)

OAA:	114809253(WBP4)

GGA:	418829(WBP4)

PCOC:

116244212(WBP4)

MGP:	100543553(WBP4)

CJO:	107308105(WBP4)

TPAI:

128092106(WBP4)

LMUT:

125687640(WBP4)

NMEL:

110387137(WBP4)

APLA:

101803435(WBP4)

ACYG:

106035016(WBP4)

CATA:

118251376(WBP4)

AFUL:

116492726(WBP4)

TGU:	100217656(WBP4)

LSR:	110470858(WBP4)

SCAN:

103812583(WBP4)

PMOA:

120505863(WBP4)

OTC:	121337250(WBP4)

PRUF:

121353263(WBP4)

GFR:	102035173(WBP4)

FAB:	101821698(WBP4)

OMA:	130254414(WBP4)

PHI:	102100648(WBP4)

PMAJ:

107200550(WBP4)

CCAE:

111934363(WBP4)

CCW:	104693173(WBP4)

CBRC:

103615175(WBP4)

ETL:	114059878(WBP4)

ZAB:	102068025(WBP4)

ACHL:

103807719(WBP4)

MMEA:

130573713(WBP4)

HRT:	120748410(WBP4)

FPG:	101920220(WBP4)

FCH:	102054545(WBP4)

CLV:	102098219(WBP4)

EGZ:	104133329(WBP4)

NNI:	104010966(WBP4)

PCRI:

104032987(WBP4)

PLET:

104626490(WBP4)

EHS:

104511191

PCAO:

104043336(WBP4)

ACUN:

113490692(WBP4)

TALA:

104366490(WBP4)

PADL:

103915922(WBP4)

AFOR:

103895960(WBP4)

ACHC:

115350607(WBP4)

HALD:

104319810(WBP4)

HLE:	104837490(WBP4)

AGEN:

126045156

GCL:

127019930

CCRI:

104164810(WBP4)

CSTI:

104555364(WBP4)

CMAC:

104481518(WBP4)

MUI:	104547876(WBP4)

BREG:

104632153(WBP4)

FGA:	104070957(WBP4)

GSTE:

104251328(WBP4)

LDI:	104353346(WBP4)

MNB:

103770037

OHA:	104336984(WBP4)

NNT:	104407526(WBP4)

SHAB:

115603756(WBP4)

PGUU:

104461713(WBP4)

ACAR:

104527423(WBP4)

CPEA:

104391554(WBP4)

AVIT:

104270894(WBP4)

CVF:	104284148(WBP4)

RTD:	128905282(WBP4)

CUCA:

104056537(WBP4)

TEO:	104377397(WBP4)

BRHI:

104492231(WBP4)

AAM:	106489180(WBP4)

AROW:

112962611(WBP4)

NPD:	112943348(WBP4)

TGT:	104573575(WBP4)

DNE:	112982645(WBP4)

SCAM:

104142505(WBP4)

ASN:	102371953(WBP4)

AMJ:	102567841(WBP4)

CPOO:

109306472(WBP4)

GGN:	109302549(WBP4)

PSS:	102449447(WBP4)

CMY:	102946469(WBP4)

CCAY:

125637238(WBP4)

DCC:	119862177(WBP4)

CPIC:

101950618(WBP4)

TST:	117870926(WBP4)

CABI:

116822813(WBP4)

MRV:	120401001(WBP4)

ACS:	100567319(wbp4)

ASAO:

132771405(WBP4)

PVT:	110084688(WBP4)

SUND:

121924925(WBP4)

PBI:	103059850(WBP4)

PMUR:

107283205(WBP4)

CTIG:

120314969(WBP4)

TSR:	106557189(WBP4)

PGUT:

117665031(WBP4)

APRI:

131199255(WBP4)

PTEX:

113439481(WBP4)

NSS:	113419800(WBP4)

VKO:	123032396(WBP4)

PMUA:

114601225(WBP4)

PRAF:

128418099(WBP4)

ZVI:	118077624(WBP4)

HCG:	128349985(WBP4)

GJA:	107124398(WBP4)

STOW:

125430934(WBP4)

EMC:	129326768(WBP4)

XLA:	446577(wbp4.S) 446748(wbp4.L)

XTR:	734007(wbp4)

NPR:	108790254(WBP4)

RTEM:

120929657(WBP4)

BBUF:

120995902(WBP4)

BGAR:

122931994(WBP4)

MUO:	115468668(WBP4)

GSH:	117363210(WBP4)

DRE:	553723(wbp4)

SRX:	107749410 107750826 107750835

SANH:

107663443(wbp4) 107703116

SGH:	107556743(wbp4)

CCAR:

109077455(wbp4)

CAUA:

113102615(wbp4)

CGIB:

127959193

PTET:

122334355(wbp4)

LROH:

127167358(wbp4)

OMC:	131542275(wbp4)

PPRM:

120465079(wbp4)

RKG:	130078037(wbp4)

MAMB:

125273413(wbp4)

CIDE:

127514324

MASI:

127445785 127449586

TROS:

130556424(wbp4)

TDW:	130424857(wbp4)

IPU:

108273303

IFU:	128615926(wbp4)

PHYP:

113530403(wbp4)

SMEO:

124391790(wbp4)

TFD:	113642923(wbp4)

TVC:	132844730(wbp4)

AMEX:

103042258(wbp4)

CMAO:

118808094(wbp4)

EEE:	113582611(wbp4)

CHAR:

122130846(wbp4)

TRU:	101070668(wbp4)

TFS:	130522908(wbp4)

TNG:	GSTEN00031835G001

LCO:	104936521(wbp4)

NCC:	104961426(wbp4)

TBEN:

117498980(wbp4)

CGOB:

115016692(wbp4)

PGEO:

117443193(wbp4)

GACU:

117546573(wbp4)

EMAC:

134860643(wbp4)

ELY:	117250051(wbp4)

EFO:	125884995(wbp4)

PLEP:

121962796(wbp4)

SLUC:

116044782(wbp4)

ECRA:

117939159(wbp4)

ESP:	116674108(wbp4)

PFLV:

114551089(wbp4)

GAT:	120820626(wbp4)

PPUG:

119220608(wbp4)

AFB:	129111842(wbp4)

CLUM:

117745942(wbp4)

PSWI:

130204638(wbp4)

MSAM:

119904254(wbp4)

SCHU:

122871781(wbp4)

CUD:	121506458(wbp4)

ALAT:

119015255(wbp4)

MZE:	101471646(wbp4)

ONL:	100694148(wbp4)

OAU:	116327087(wbp4)

OLA:	101161956(wbp4)

OML:	112142040 112160091

CSAI:

133425037(wbp4)

XMA:	102238330(wbp4)

XCO:	114140979(wbp4)

XHE:	116716250(wbp4)

PRET:

103477691(wbp4)

PFOR:

103130067(wbp4)

PLAI:

106942716(wbp4)

PMEI:

106911611(wbp4)

GAF:	122827284(wbp4)

PPRL:

129378771(wbp4)

CVG:	107098080(wbp4)

CTUL:

119780780(wbp4)

GMU:	124861883(wbp4)

NFU:	107377252(wbp4)

KMR:	108247998(wbp4)

ALIM:

106531089(wbp4)

NWH:	119428858(wbp4)

AOCE:

111587767(wbp4)

MCEP:

125001169(wbp4)

CSEM:

103389503(wbp4)

POV:	109638904(wbp4)

SSEN:

122773201(wbp4)

HHIP:

117778503(wbp4)

HSP:	118103450(wbp4)

SMAU:

118302270(wbp4)

LCF:

108894885

SDU:	111234018(wbp4)

SLAL:

111644460(wbp4)

XGL:	120798009(wbp4)

HCQ:	109528405(wbp4)

SSCV:

125988641

SBIA:

133506780(wbp4)

PEE:	133403566(wbp4)

PTAO:

133480359(wbp4)

BPEC:

110170874(wbp4)

MALB:

109971962(wbp4)

BSPL:

114848928(wbp4)

SJO:	128354198(wbp4)

SASA:

106575454 106592210

STRU:

115179124 115196237

OTW:	112235910 112236948

OMY:	110527374 110527375(wbp4)

OGO:	124008240 124010617

ONE:	115120095 115132403

OKI:	109890370 109890533

OKE:	118377146 118383711

SALP:

112074050 112075151(wbp4)

SNH:	120033127(wbp4) 120051376

CCLU:

121533040(wbp4)

ELS:	105019818(wbp4)

SFM:	108920418(wbp4)

PKI:	111852774(wbp4)

AANG:

118214114 118223176

LOC:	102698040(wbp4)

PSPA:

121320956(wbp4) 121327912

ARUT:

117405754 117406794

PSEX:

120523728(wbp4)

LCM:	102355139(WBP4)

CMK:	103187602(wbp4)

RTP:	109922091(wbp4)

CPLA:

122555471(wbp4)

HOC:	132820939(wbp4)

LERI:

129702746(wbp4)

BFO:

118419414

BBEL:

109467822

CIN:	100169913(zf(u1like)-1)

SCLV:

120342111

SPU:	100888826 577107

LPIC:

129260928

APLC:

110975941

SKO:

100373917

DME:	Dmel_CG4291(CG4291)

DER:

6541749

DSE:

116801939

DSI:	Dsimw501_GD22937(Dsim_GD22937)

DYA:	Dyak_GE15876

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI18009

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:

AOQ:

TDA:

MDE:

SCAC:

LCQ:

LSQ:	119603383 119605825

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

CQU:	CpipJ_CPIJ012871

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

ATD:

AGB:

LDC:

NVL:

BMOR:

BMAN:

MSEX:

DPL:	KGM_213665

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

ZCE:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:

PGW:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

BTAB:

DCI:	103511468 103523794

CLEC:

HHAL:

NLU:

HVI:

MQU:

PHU:	Phum_PHUM350980

FOC:

TPAL:

ZNE:

CSEC:

DPX:	DAPPUDRAFT_227256

DMK:

116921827

DPZ:

124316419

PVM:	113827123 113827130

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

EAF:

LSM:

TCF:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

PTEP:

ABRU:

UDV:

SDM:

CEL:	CELE_F56G4.4(wbp-4)

CBR:

CBG_08044

CRQ:	GCK72_003366

LOA:	LOAG_05542

HRO:	HELRODRAFT_191166

LGI:	LOTGIDRAFT_239443

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CVN:

CANU:

OED:

MYI:

PMAX:

MMER:

RPHI:

DPOL:

OBI:

OSN:

LAK:

SMM:	Smp_133940

SHX:	MS3_00010843(WBP4_1)

OVI:	T265_14467

EGL:

NVE:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

TAD:	TRIADDRAFT_56241

ATH:

AT1G49590

ALY:

9327585

CRB:

17900391

CSAT:

104742485 104758263 104777872

EUS:	EUTSA_v10011741mg

BRP:

103871383

BNA:	106346141 106424431

BOE:

106298301

RSZ:	108854109 108861752

THJ:

104801600

CPAP:

110813677

CIT:

102609013

CIC:	CICLE_v10029963mg

PVY:	116125035 116128690

MINC:

123226861

TCC:

18607901

GRA:

105795278

GHI:	107928010 121222241

GAB:

108474761

HSYR:

120158163 120171565 120177945

DZI:

111308923

EGR:

104418755

GMX:	100776500 100779677 100804274

GSJ:	114372392 114391132 114418070

PVU:	PHAVU_007G247000g

VRA:

VAR:

VUN:

VUM:

CCAJ:

APRC:

MTR:

TPRA:

CAM:

PSAT:

VVO:

LJA:	Lj4g3v0575060.1(Lj4g3v0575060.1)

ADU:	107470054 107478850

AIP:

107612337

AHF:	112715549 112772037 112790370

LANG:

109343568

PCIN:

129284793

QSA:	O6P43_011694

FVE:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:	103454492 114824806

MSYL:

PXB:

ZJU:

MNT:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

JCU:

HBR:

MESC:

POP:

PEU:

PALZ:

JRE:

CILL:

CAVE:

QSU:	111990352 112004220

QLO:

115966235

TWL:	120002966 120011449

VVI:

VRI:

SLY:

SPEN:

SOT:

SSTN:

SDUL:

CANN:

LBB:

NTA:	107788750 107814004

NSY:

NTO:

NAU:

INI:

ITR:

SIND:

OEU:

EGT:

SSPL:

SMIL:

SHIS:

APAN:

HAN:

ECAD:

LSV:

CCAV:

DCR:

CSIN:

114261754 114279225 114301292

RVL:

AEW:

BVG:

SOE:

CQI:	110696594 110737433

ATRI:

MOF:

NNU:

MING:

TSS:

PSOM:

OSA:

DOSA:

Os06t0215200-01(Os06g0215200)

OBR:

OGL:

BDI:

ATS:

TDC:	119330393 119337695

TAES:

123150874 123157979 123165227

TUA:

125522302

LPER:

127317728

LRD:	124685288 124685433

SBI:

ZMA:

SITA:

SVS:

PVIR:

120670348 120703181 120703273

PHAI:

112888965

PDA:

103722945

EGU:

105034421

MUS:	103969611 103992265

ZOF:	121991657 121995539

DCT:

PEQ:

AOF:

MSIN:

NCOL:

ATR:

SMO:	SELMODRAFT_402249 SELMODRAFT_440013

PPP:

112291356

VCN:	VOLCADRAFT_116255

MNG:

MNEG_9886

CSL:	COCSUDRAFT_54684

CVR:	CHLNCDRAFT_57343

APRO:

F751_3030

OTA:	OT_ostta05g03680

MIS:	MICPUN_100589

CNE:

CNN00960

CNB:

CNBN0950

CNG:	CNAG_06368

CGI:	CGB_N1360C

CDEU:

CNBG_9560

TMS:	TREMEDRAFT_64085

CCAC:

CcaHIS019_0311070(CcaverHIS019_0311070)

TVS:	TRAVEDRAFT_56498

DSQ:	DICSQDRAFT_13523

PCO:	PHACADRAFT_210366

SHS:	STEHIDRAFT_102376

HIR:	HETIRDRAFT_246235

PSQ:	PUNSTDRAFT_98839

ADL:	AURDEDRAFT_111346

FME:	FOMMEDRAFT_55883

GTR:	GLOTRDRAFT_137558

RSX:	RhiXN_06541

LBC:	LACBIDRAFT_313718

CCI:	CC1G_04494

ABP:	AGABI1DRAFT65486(AGABI1DRAFT_65486)

ABV:	AGABI2DRAFT185019(AGABI2DRAFT_185019)

MPR:	MPER_15190

MRR:	Moror_6887

E1B28_000756

CPUT:

CONPUDRAFT_163763

SLA:	SERLADRAFT_466108

WSE:	WALSEDRAFT_29800

UMA:	UMAG_00971

PFP:	PFL1_01070

SGRA:

EX895_006231

MGL:

MGL_4213

MRT:

MRET_1418

PGR:	PGTG_03480

MLR:	MELLADRAFT_73302

SRE:	PTSG_01190

PYO:	PY17X_1042000

PCB:	PCHAS_1040300

PBE:	PBANKA_1039500

PKN:	PKNH_1355700

PVX:	PVX_086310

PCY:	PCYB_135390

TAN:

TA10155

TPV:

TP04_0753

TOT:	TOT_040000177

BEQ:	BEWA_010110

BBO:	BBOV_III008510

BMIC:

BmR1_04g06920

CPV:

cgd3_1440

CHO:	Chro.30174

TPS:	THAPSDRAFT_24763

PIF:	PITG_01944

PSOJ:

PHYSODRAFT_497071

EHX:	EMIHUDRAFT_462236

GTT:	GUITHDRAFT_113284

NGR:	NAEGRDRAFT_49162

» show all

Reference

PMID:9724750

Authors

Bedford MT, Reed R, Leder P

Title

WW domain-mediated interactions reveal a spliceosome-associated protein that binds a third class of proline-rich motif: the proline glycine and methionine-rich motif.

Journal

Proc Natl Acad Sci U S A 95:10602-7 (1998)
DOI:10.1073/pnas.95.18.10602

Sequence

[hsa:11193] [mmu:22380]

Reference

PMID:19592703

Authors

Huang X, Beullens M, Zhang J, Zhou Y, Nicolaescu E, Lesage B, Hu Q, Wu J, Bollen M, Shi Y

Title

Structure and function of the two tandem WW domains of the pre-mRNA splicing factor FBP21 (formin-binding protein 21).

Journal

J Biol Chem 284:25375-87 (2009)
DOI:10.1074/jbc.M109.024828

Sequence

[hsa:11193]

LinkDB

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