Entry
Symbol
eryBIV, tylCIV, tylC2
Name
dTDP-4-keto-6-deoxy-L-hexose 4-reductase [EC:1.1.1.-]
Pathway
map00523 Polyketide sugar unit biosynthesis
map01110 Biosynthesis of secondary metabolites
map01250 Biosynthesis of nucleotide sugars
Module
M00798 dTDP-L-mycarose biosynthesis
Reaction
R06436 dTDP-L-mycarose:NADP+ 4-oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00523 Polyketide sugar unit biosynthesis
K13318 eryBIV, tylCIV, tylC2; dTDP-4-keto-6-deoxy-L-hexose 4-reductase
Genes
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Taxonomy UniProt
Reference
Authors
Summers RG, Donadio S, Staver MJ, Wendt-Pienkowski E, Hutchinson CR, Katz L.
Title
Sequencing and mutagenesis of genes from the erythromycin biosynthetic gene cluster of Saccharopolyspora erythraea that are involved in L-mycarose and D-desosamine production.
Journal
Sequence
Reference
Authors
Bate N, Butler AR, Smith IP, Cundliffe E
Title
The mycarose-biosynthetic genes of Streptomyces fradiae, producer of tylosin.
Journal
Sequence
Reference
Authors
Takahashi H, Liu YN, Chen H, Liu HW
Title
Biosynthesis of TDP-l-mycarose: the specificity of a single enzyme governs the outcome of the pathway.
Journal
LinkDB
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