KEGG   ORTHOLOGY: K13319
Entry
K13319            Tight     KO                                     
Symbol
oleU
Name
4-ketoreductase
Pathway
map00523  Polyketide sugar unit biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01250  Biosynthesis of nucleotide sugars
Module
M00801  dTDP-L-olivose biosynthesis
Reaction
R06434  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    K13319  oleU; 4-ketoreductase
Genes
AG: AAD55455(oleU)
Reference
  Authors
Aguirrezabalaga I, Olano C, Allende N, Rodriguez L, Brana AF, Mendez C, Salas JA
  Title
Identification and expression of genes involved in biosynthesis of L-oleandrose and its intermediate L-olivose in the oleandomycin producer Streptomyces antibioticus.
  Journal
Antimicrob Agents Chemother 44:1266-75 (2000)
DOI:10.1128/AAC.44.5.1266-1275.2000
  Sequence
LinkDB

KEGG   REACTION: R06434
Entry
R06434                      Reaction                               
Definition
dTDP-4-oxo-2,6-dideoxy-L-mannose + NADPH + H+ <=> dTDP-L-olivose + NADP+
Equation
Comment
4-oxoreductase,AveB4 OleU
Reaction class
RC00001  C00005_C00006
RC00182  C11920_C11927
Pathway
rn00523  Polyketide sugar unit biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01250  Biosynthesis of nucleotide sugars
Module
M00801  dTDP-L-olivose biosynthesis
Orthology
K13319  4-ketoreductase
LinkDB

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