KEGG   ORTHOLOGY: K13557
Entry
K13557                      KO                                     
Symbol
neoN, neoH
Name
neomycin C epimerase [EC:5.1.3.-]
Pathway
map00524  Neomycin, kanamycin and gentamicin biosynthesis
map01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    K13557  neoN, neoH; neomycin C epimerase
Enzymes [BR:ko01000]
 5. Isomerases
  5.1  Racemases and epimerases
   5.1.3  Acting on carbohydrates and derivatives
    5.1.3.-
     K13557  neoN, neoH; neomycin C epimerase
Other DBs
RN: R08904
COG: COG0535
Genes
SRN: A4G23_05123
SFB: CP974_27340
AG: BAD95825(neoH)
Reference
  Authors
Kudo F, Yamamoto Y, Yokoyama K, Eguchi T, Kakinuma K
  Title
Biosynthesis of 2-deoxystreptamine by three crucial enzymes in Streptomyces fradiae NBRC 12773.
  Journal
J Antibiot (Tokyo) 58:766-74 (2005)
DOI:10.1038/ja.2005.104
  Sequence
Reference
  Authors
Kudo F, Hoshi S, Kawashima T, Kamachi T, Eguchi T
  Title
Characterization of a radical S-adenosyl-L-methionine epimerase, NeoN, in the last step of neomycin B biosynthesis.
  Journal
J Am Chem Soc 136:13909-15 (2014)
DOI:10.1021/ja507759f
LinkDB

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