KEGG   ORTHOLOGY: K13609
Entry
K13609                      KO                                     
Symbol
dpkA, lhpD
Name
delta1-piperideine-2-carboxylate reductase [EC:1.5.1.21]
Pathway
map00310  Lysine degradation
map00960  Tropane, piperidine and pyridine alkaloid biosynthesis
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Module
M00960  Lysine degradation, bacteria, L-lysine => D-lysine => succinate
Reaction
R02203  L-pipecolate:NADP+ 2-oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    K13609  dpkA, lhpD; delta1-piperideine-2-carboxylate reductase
  09110 Biosynthesis of other secondary metabolites
   00960 Tropane, piperidine and pyridine alkaloid biosynthesis
    K13609  dpkA, lhpD; delta1-piperideine-2-carboxylate reductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.21  1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH)
     K13609  dpkA, lhpD; delta1-piperideine-2-carboxylate reductase
Other DBs
COG: COG2055
GO: 0047125
Genes
EAS: Entas_0546
KPN: KPN_04791
KPU: KP1_0749
KPM: KPHS_06400
KPP: A79E_4358
KPH: KPNIH24_03290
KPZ: KPNIH27_03165
KPV: KPNIH29_03485
KPW: KPNIH30_03445
KPY: KPNIH31_04585
KPT: VK055_2646(dpkA)
KPR: KPR_0871
KPJ: N559_4502
KPX: PMK1_02252(comC)
KPNU: LI86_23140
KPNK: BN49_4402
KVA: Kvar_4453
KPE: KPK_4820
EAE: EAE_10410
EAR: CCG31912
RTG: NCTC13098_06399(ybiC_3)
CRO: ROD_48381(allD)
CAMA: F384_16275
KIE: NCTC12125_03109(ybiC)
PSGC: G163CM_29690(lhpD)
EBF: D782_3914
SMAR: SM39_1303
SPE: Spro_1835
SPLY: Q5A_009085(lhpD)
SMAF: D781_1745
SERF: L085_19550
SFJ: SAMEA4384070_1859(ybiC_1)
SGRI: SGBXF1_01840(comC)
EAM: EAMY_2586
EAY: EAM_2481
EPY: EpC_10400
PAE: PA1252
PAEV: N297_1291
PAEI: N296_1291
PAEP: PA1S_19655
PAEM: U769_19495
PAEL: T223_20745
PAEG: AI22_14310
PAEC: M802_1288
PAEO: M801_1291
SECH: B18_17995
PPU: PP_3591(dpkA)
PPF: Pput_2181
PPT: PPS_3084
PPB: PPUBIRD1_2201(dpkA)
PPI: YSA_00209
PPX: T1E_2270
PPUH: B479_15340
PPUT: L483_18820
PPUN: PP4_22360
PPUD: DW66_3356
PMON: X969_14820
PMOT: X970_14465
PST: PSPTO_2359(allD)
PSB: Psyr_2143
PSYR: N018_10045
PAST: N015_15990
PFS: PFLU_2704
PFB: VO64_5794
PMAN: OU5_0213
PMUD: NCTC8068_02634(ybiC)
PEN: PSEEN2669
PANR: A7J50_3234
PSIL: PMA3_13110
PTAE: NCTC10697_02571(ybiC)
PSOA: PSm6_48760
PSTT: CH92_01000
MNK: RE428_41090(lhpD)
PIN: Ping_2116
GAI: IMCC3135_33065(lhpD)
HEL: HELO_3404(lhpD)
HAM: HALO3638
COBE: CLAM6_13330(lhpD_1) CLAM6_21120(lhpD_2)
CHJ: NCTC10426_00338(allD)
RME: Rmet_5095
BMA: BMAA1423
BMAE: DM78_4013
BMAI: DM57_08740
BMAF: DM51_5067
BMAZ: BM44_4895
BMAB: BM45_3797
BPS: BPSS0328
BPSE: BDL_3560
BPSM: BBQ_5871
BPSU: BBN_3724
BPSD: BBX_5398
BPK: BBK_5540
BPSH: DR55_5019
BPSA: BBU_5789
BPSO: X996_4788
BUT: X994_4288
BTQ: BTQ_5351
BTJ: BTJ_4003
BTZ: BTL_4827
BTD: BTI_4403
BTV: BTHA_5403
BTHE: BTN_4477
BTHM: BTRA_4743
BTHA: DR62_4591
BTHL: BG87_4808
BOK: DM82_4397
BOC: BG90_3679
BSAV: WS86_20465
BVE: AK36_4220
BCJ: BCAM1263
BCEN: DM39_3738
BCEW: DM40_4175
BCEO: I35_5111
BAM: Bamb_3547
BMJ: BMULJ_04059(ybiC)
BMU: Bmul_4451
BMK: DM80_3615
BMUL: NP80_4164
BCT: GEM_4480
BCED: DM42_3830
BDL: AK34_4217
BCON: NL30_06290
BUB: BW23_4935
BLAT: WK25_23220
BTEI: WS51_03990
BSEM: WJ12_26160
BPSL: WS57_07715
BMEC: WJ16_24790
BSTG: WT74_25105
BGO: BM43_7272
BUK: MYA_4528
BUL: BW21_3936
PLG: NCTC10937_02096(ybiC)
BPE: BP2521
BPC: BPTD_2478
BPER: BN118_1505
BPET: B1917_1338
BPEU: Q425_21020
BBR: BB2374
BPT: Bpet1261(mdh3)
PUT: PT7_1266
AJS: Ajs_3134
SME: SM_b20261
SMER: DU99_32065
SMD: Smed_3870
EAD: OV14_a1330(mdh)
ATU: Atu4676
AVI: Avi_7014(mdh)
RHT: NT26_0738
SHZ: shn_20835
KAI: K32_32390
BME: BMEII1005
BMEL: DK63_2251
BMEE: DK62_3156
BMF: BAB2_0960
BABO: DK55_2904
BABR: DO74_2219
BABT: DK49_2335
BABB: DK48_2893
BABU: DK53_2907
BABS: DK51_2393
BABC: DO78_2150
BMS: BRA0240
BSZ: DK67_2261
BOV: BOV_A0219
BCS: BCAN_B0242(mdh)
BCAR: DK60_3115
BCAS: DA85_11655
BMR: BMI_II236
BPV: DK65_2236
OAN: Oant_2899
OAH: DR92_3606
SNO: Snov_0154
PHL: KKY_1203
MMED: Mame_00343(comC)
BVY: NCTC9239_01937(ybiC)
ASTD: ATDW_33350
TSV: DSM104635_03484(ybiC)
RUT: FIU92_05045(comC1)
KVU: EIO_3229
SMAZ: LH19_24995
SPHU: SPPYR_0556
STAX: MC45_12620
SSAN: NX02_14845
SSY: SLG_18160
SPAG: sphantq_02874(dpkA)
ANH: A6F65_00113(comC)
SHUM: STHU_40240
PUB: SAR11_0966(yiaK)
MPH: MLP_36600
PAUT: Pdca_13340(lhpD)
PLH: VT85_24400(comC)
AG: BAD89743(dpkA)
 » show all
Reference
PMID:6801013
  Authors
Payton CW, Chang YF
  Title
delta1-piperideine-2-carboxylate reductase of Pseudomonas putida.
  Journal
J Bacteriol 149:864-71 (1982)
DOI:10.1128/JB.149.3.864-871.1982
Reference
  Authors
Muramatsu H, Mihara H, Kakutani R, Yasuda M, Ueda M, Kurihara T, Esaki N
  Title
The putative malate/lactate dehydrogenase from Pseudomonas putida is an NADPH-dependent delta1-piperideine-2-carboxylate/delta1-pyrroline-2-carboxylate reductase involved in the catabolism of D-lysine and D-proline.
  Journal
J Biol Chem 280:5329-35 (2005)
DOI:10.1074/jbc.M411918200
  Sequence
Reference
  Authors
Watanabe S, Tanimoto Y, Yamauchi S, Tozawa Y, Sawayama S, Watanabe Y
  Title
Identification and characterization of trans-3-hydroxy-l-proline dehydratase and Delta(1)-pyrroline-2-carboxylate reductase involved in trans-3-hydroxy-l-proline metabolism of bacteria.
  Journal
FEBS Open Bio 4:240-50 (2014)
DOI:10.1016/j.fob.2014.02.010
  Sequence
[pae:PA1252]
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