KEGG ORTHOLOGY: K13649

ORTHOLOGY: K13649

Entry

K13649                      KO

Symbol

FOLR

Name

folate receptor

Pathway

map01523

Antifolate resistance

map04144

Endocytosis

map04981

Folate transport and metabolism

Disease

H01295

Neurodegeneration due to cerebral folate transport deficiency

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K13649  FOLR; folate receptor
09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    K13649  FOLR; folate receptor
09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    K13649  FOLR; folate receptor
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K13649  FOLR; folate receptor
   04147 Exosome
    K13649  FOLR; folate receptor
   00537 Glycosylphosphatidylinositol (GPI)-anchored proteins
    K13649  FOLR; folate receptor
Transporters [BR:ko02000]
Other transporters
  Others
   K13649  FOLR; folate receptor
Exosome [BR:ko04147]
Exosomal proteins
  Exosomal proteins of breast milk
   K13649  FOLR; folate receptor
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:ko00537]
Receptors
  K13649  FOLR; folate receptor

Other DBs

GO:	0005542 0061714

TC:

9.B.92.1

Genes

HSA:	2348(FOLR1) 2350(FOLR2) 2352(FOLR3)

PTR:	100614013(FOLR2) 451401(FOLR1) 748291(FOLR3)

PPS:	100993229(FOLR2) 100994139 100995164(FOLR3)

GGO:	101123692(FOLR2) 101152334 101152944

PON:	100442083(FOLR3) 100442445(FOLR2) 100444277

PPYG:

129007812 129008184 129008901(FOLR2)

NLE:	100589102 100589656(FOLR3)

HMH:	116476636(FOLR2) 116476638(FOLR1) 116476639(FOLR3)

SSYN:

129484576(FOLR2) 129484577(FOLR1) 129484578(FOLR3)

MCC:	718347 718378 718388(FOLR1) 718405(FOLR2)

MCF:	102132305(FOLR1) 102132686 102147063(FOLR2) 135967064

MTHB:

126935209 126935216 126935217 126935221

MNI:	105468694 105468697(FOLR1) 105468698(FOLR2)

CSAB:

103247990 103247991 103247993(FOLR2)

CATY:

105578794(FOLR2) 105578795(FOLR1) 105578796 105578798

PANU:

101000220(FOLR3) 101000788 101001135(FOLR1) 116269732

TGE:	112605922 112606583(FOLR2) 112606584(FOLR1) 112606585 112617682

MLEU:

105549234(FOLR2) 105549237(FOLR3) 105549266(FOLR1)

RRO:	104665153(FOLR2) 104665154(FOLR1) 104665155

RBB:	108543774(FOLR2) 108543775(FOLR1) 108543777

TFN:	117079807(FOLR2) 117079808(FOLR1) 117079809

PTEH:

111540893 111540895 111540897

CANG:

105522311(FOLR3) 105522312 105522313(FOLR2)

CJC:	100397175(FOLR3) 100411452(FOLR2) 100411818(FOLR1)

SBQ:	101027508(FOLR2) 101027813 101029639 101054127(FOLR1)

CIMI:

108307530(FOLR2) 108307531 119466690(FOLR1)

ANAN:

105720380(FOLR3) 105720385(FOLR1) 105720386(FOLR2)

CSYR:

103249894 103268497(FOLR3) 103271758

MMUR:

105860275 105860321(FOLR2) 105860322

LCAT:

123641077(FOLR2) 123641079

PCOQ:

105811512(FOLR3) 105811513(FOLR1) 105811514(FOLR2)

OGA:	100944015 100951286 100951599(FOLR3)

MMU:	14275(Folr1) 14276(Folr2)

MCAL:

110297345(Folr2) 110298622

MPAH:

110325815 110331536(Folr2)

RNO:	171049(Folr1) 293154(Folr2)

MCOC:

116100667

ANU:	117714148 117722298

ASYL:

127664623(Folr2) 127681278

MUN:	110544670 110557555

CGE:	100689330(Folr1)

MAUA:

PROB:

PLEU:

MORG:

MFOT:

126488841 126488842 126492586

AAMP:

119819073 119827170

NGI:	103738633 103750805

HGL:	101699175(Folr1) 101721569(Folr2)

CPOC:

100725439(Folr1)

CCAN:

109693007

DORD:

105983965(Folr2) 105984109

DSP:	122115723 122115743(Folr2)

PLOP:

125361192 125361194

NCAR:

124958998 124959825

MMMA:

107135554(Folr2) 107160514

ITI:	101966601(Folr1) 101967276(Folr2)

OCU:	100341917 100342424(FOLR1)

OPI:	101517800 101518046 101520838(FOLR1) 105941850

TUP:	102484666(FOLR2) 102501879(FOLR1)

GVR:	103585873(FOLR2) 103585874(FOLR1)

CFA:	100684665 476816 609612 609621

CLUD:

112667311 112667463(FOLR2) 112667464 112667963

VVP:	112928688(FOLR2) 112928755

VLG:	121475954 121475967 121498500

NPO:	129506581 129506690 129506718(FOLR1)

AML:

100482963

UMR:	103678020 103678021 103678106

UAH:	113269262(FOLR1) 113269263(FOLR2) 113269269

UAR:	123782546(FOLR3) 123782547(FOLR1) 123782549(FOLR2)

ELK:	111159442 111159443 111159447

LLV:	125079356 125079357 125079358

MPUF:

101687090 101687385(FOLR1) 101688243(FOLR2)

MNP:	132011887 132023979(FOLR2)

MLK:	131807890(FOLR2) 131807905

NVS:	122912627 122912628(FOLR2) 122912630

ORO:	101365545(FOLR1) 101366136(FOLR2) 101374828

EJU:	114218687 114218688 114218777(FOLR2)

ZCA:	113915116 113915117(FOLR2)

NSU:	110593363 110593364 110593377(FOLR2)

LWW:	102728256(FOLR2) 102729082 102729382

FCA:	101084221(FOLR1) 101084733 101095853(FOLR2)

PYU:	121039230 121039231 121039232

PCOO:

112865737

PBG:	122483381 122483382(FOLR2) 122483383

PVIV:

125177088 125177089(FOLR2) 125177090

LRUF:

124505445 124505446 124505570

LGF:	123601211 123601212(FOLR2) 123601213

AJU:	106970926 106970939 106970941

PTG:	102968953 102969559(FOLR1) 102969841(FOLR2)

PPAD:

109267137 109267139 109267142

PUC:	125937288 125937292 125937322

PLEZ:

122199716 122199718(FOLR2) 122199719

HHV:	120236664 120245128 120245129(FOLR2) 120245130

BTA:	507672(FOLR2) 516067(FOLR3) 539750(FOLR1)

BOM:	102275702 102276550 102276827(FOLR2)

BIU:	109569920 109569935

BBUB:

102389254(FOLR2) 102390454 102390798

BBIS:

104995565(FOLR3) 104995567(FOLR1) 104995568(FOLR2)

CHX:	102174322 102174766(FOLR2) 102175046(FOLR1)

OAS:	101120775(FOLR3) 101121452(FOLR2)

BTAX:

128060322 128060409 128060534

CSUM:

138092433 138092494 138092547

ODA:	120862128 120876731 120876733

CCAD:

122449724 122450155 122450156

MREE:

136173999 136174286

OVR:	110131314 110139450 110139458

MBEZ:

129554628(FOLR3) 129554630 129554631(FOLR1)

SSC:	396784(FOLR1) 396853(FOLR2) 397579(FOLR1)

CFR:	102517455 102517702

CBAI:

105083285 105083286(FOLR1) 105083288(FOLR2)

CDK:	105096710 105096725(FOLR2)

VPC:	102535143(FOLR2)

BACU:

102997287(FOLR2) 102997580(FOLR1)

BMUS:

118898714 118898715(FOLR2) 118898716

LVE:	103078690(FOLR2) 103080706 103081344

OOR:	101290234 101290489

LALB:

132525298 132525299 132525300

DLE:	111170568 111170569(FOLR1) 111170572

PCAD:

102995560 102995829 102996106(FOLR2)

PSIU:

116757467 116757468(FOLR2) 116757469

NASI:

112390749 112390774(FOLR2) 112390775

ECB:	100052723(FOLR3) 100059683 100066065(FOLR2) 100066084(FOLR1)

EPZ:	103549327(FOLR2) 103549329 103549331 103554973

EAI:	106831658 106831659 106831660(FOLR2) 106836927

MYB:	102248426 102248730 102254055 102255082 102255389

MYD:	102755919(FOLR2) 102756195(FOLR1) 102760531

MMYO:

118662811(FOLR3) 118664698(FOLR2) 118664699 118664700(FOLR1)

MLF:	102417105(FOLR1) 102417418 102443115

MDT:	132240840 132240841(FOLR1) 132240842 132240862

MYUM:

139017301(FOLR2) 139017302 139018189 139018190

PKL:	118713444 118713445 118713456

EFUS:

103293566 103293661 129151089 129151179

MNA:	107533671 107541157(FOLR3) 107541158

DRO:	112315921 112315922 112315996 112315998

SHON:

119002622 119002635 119002636 119002649

AJM:	119042140 119042141 119042145 128628265

PDIC:

114498866 114499468 114500346 114500347(FOLR2)

PHAS:

123805426 123805427(FOLR1)

MMF:	118627690 118627691 118627692 118627693

PPAM:

129072618 129072619 129072620(FOLR2) 129072719

HAI:	109372410(FOLR2) 109372411(FOLR1)

RFQ:	117030236 117030240

PALE:

102890350(FOLR2) 102890596(FOLR1) 102895951

PGIG:

120590300 120590301

PVP:	105303657(FOLR2) 105303658 105303691

RAY:	107517325 107517375(FOLR2) 107517376

MJV:	108405085 108405096(FOLR2) 118969355

TOD:

SARA:

SFUM:

SETR:

LAV:	100665164 100674271 100674557

TMU:	101350825 101351081 101351346

ETF:	101640916 101641226

DNM:	101418447 101418894 101420076

MDO:	100015543 100015612 100015645

GAS:	123235950 123239657 123241151 123254892 123255375

SHR:	100930340(FOLR1)

AFZ:

127555253

PCW:	110195206 110195207

TVP:	118837421 118838557 118838622 118844310

PBRV:

138143492 138154902(IZUMO1R) 138172446

OAA:

100082740

TACU:

119948729

GGA:	395638(FOLR1)

PCOC:

116233917 116239515

MGP:	100543080 100548327

CJO:

TPAI:

LMUT:

NMEL:

APLA:

ACYG:

CATA:

AFUL:

TGU:	100220024 100227500

LSR:	110473113 110474966

SCAN:

103820749

PMOA:

120499974 120500068

OTC:	121334242 121345421

PRUF:

121354726 121355135

ATRC:

139591448 139593024

GFR:	102037080 102044934(FOLR1)

FAB:	101808380 101815314(FOLR1)

OMA:	130249462 130253498

PHI:	102102259 102105988 102112562

PMAJ:

107204728 107207618

CCAE:

111940834 111942781 111945999

CCW:	104686974 104698076

CBRC:

103613838 103624066

ACOE:

138114275 138120342

ETL:	114059628 114071159

ZAB:

102066078

ZLE:	135454139 135456728

ACHL:

103804547 103811138

SVG:	106856626 106861737

MMEA:

130579881 130582749

HRT:	120747865 120748733 120766047

SATI:

136358255 136375232

CCIC:

134041444 134058219

FPG:	101910846 101918194(FOLR1)

FCH:	102051087 102057153

CCRI:

NNT:

SHAB:

ACUN:

TALA:

ACHC:

HALD:

HLE:	104837563(FOLR3) 104837574

AGEN:

HHAR:

GCL:

CSTI:

LDI:

MNB:

DPUB:

PPUS:

AVIT:

BRHI:

EGZ:

NNI:	104011873 104014839

PCRI:

PCAO:

PADL:

AFOR:

FGA:

GSTE:

CLV:	102083480 102090726

MUI:	104534139 104542516

PGUU:

PLET:

CMAC:

CUCA:

TEO:

BREG:

OHA:

ACAR:

CPEA:

CVF:

RTD:	128904291 128918190

CRID:

134513996 134515905

DNE:

112993740

ASN:	102373359 102374202 102386152 106723144

AMJ:	102557786 102562241 102562970(FOLR1) 102577368

GGN:

109288698

PSS:	102446246 102448282

CMY:	102929386 119567468

CCAY:

125631562 125631575 125631582

DCC:	119849619 119861599 119861846

CPIC:

101931390 101931666 101931959

CABI:

116832115 116832120

MRV:	120371691(FOLR3) 120372186 120395997

ASAO:

132770292

PVT:

110078082

PBI:	103050457(FOLR2)

PMUR:

CTIG:

PGUT:

APRI:

VKO:

PMUA:

PRAF:

ZVI:

HCG:

GJA:

STOW:

EMC:

XLA:	444543(folr1.L)

XTR:	394697(folr1)

NPR:

108803573

BBUF:

120994222(FOLR2)

BGAR:

PWL:

MUO:

GSH:

DRE:	100073336(folr)

SRX:

107710498

SANH:

107679447

SGH:

107557663

CCAR:

109053182(folr)

CAUA:

113114674

CGIB:

127972303

PTET:

122332941(folr)

LROH:

127177634(folr)

OMC:	131554350(folr)

PPRM:

120478254(folr)

RKG:	130074085 130085493

MAMB:

125248111(folr)

CIDE:

127494931

CERY:

137004460(folr)

MASI:

127421840

TROS:

130564503(folr)

TDW:	130428526(folr)

MANU:

129438759(folr)

PDAB:

135770235(folr)

IPU:	108277654(folr)

PHYP:

113544605

SMEO:

124394971(folr)

TFD:	113637838(folr)

TVC:	132858133(folr)

CGAR:

128533467(folr)

TRN:	134334740(folr)

AMEX:

103026309(folr)

CMAO:

118802299(folr)

EEE:

113581593

CHAR:

105913024(folr)

SPIL:

134099265(folr)

TRU:

101065672

TNG:	GSTEN00005117G001

LCO:	104920128(folr2)

NCC:

104968280

TBEN:

117470428(folr)

CGOB:

115017520

PGEO:

117457415(folr)

GACU:

117534909(folr)

EMAC:

134880825(folr)

ELY:	117259521(folr)

EFO:	125889332(folr)

PLEP:

121943418(folr)

SLUC:

116045603(folr)

ECRA:

117942522(folr)

ESP:	116687082(folr2)

PFLV:

114552884

GAT:	120818178(folr)

PPUG:

119214001(folr)

AFB:	129094776(folr)

CLUM:

117741710(folr)

PSWI:

130211382(folr)

CANA:

137790870(folr)

CVE:	137877167(folr)

MSAM:

119883577(folr)

SCHU:

122878893(folr)

CUD:	121525782(folr)

SPUL:

138597008(folr)

LMIX:

132980303(folr)

ALAT:

119033460(folr)

ASTR:

137596313(folr)

MZE:

101484157

ONL:

100710946

OAU:	116330425(folr)

OLA:

101171932

OML:	112149905(folr)

CSAI:

133441674(folr)

XMA:

102228631

XCO:	114162012(folr2)

XHE:

116707771

PRET:

103474473(folr2)

PFOR:

103146277(folr2)

PLAI:

106939933

PMEI:

106927835(folr2)

GAF:	122832945(folr)

PPRL:

129358730(folr)

CVG:

107091938

CTUL:

119771765(folr)

GMU:	124883609(folr)

NFU:

107380468

KMR:	108240464(folr)

ALIM:

106517266

NWH:	119411532(folr)

AOCE:

111570842(folr)

EJA:	138197172(folr)

BFRE:

138631988(folr)

MCEP:

125013390(folR)

CSEM:

103378552

POV:	109634551(folr2)

SSEN:

122773175(folr)

SSOE:

131462192(folr)

HHIP:

117773253(folr)

HSP:	118105918(folr)

PPLT:

128439791(folr)

SMAU:

118299701(folr)

LCF:	108886608(folr)

SDU:	111224128(folr2)

SLAL:

111655305(folr2)

XGL:	120791766(folr)

HCQ:	109525467(folr2)

SSCV:

125972761(folr)

SBIA:

133505358(folr)

PEE:	133405355(folr)

PTAO:

133482581(folr)

BPEC:

110174406(folr2)

ENY:	140375424(folr)

BSPL:

114867964(folr)

SJO:	128360990(folr)

SSCO:

133980698(folr)

GMH:	115561632(folr2)

SASA:

100196843(folr1)

STRU:

115206595

OTW:	112267302(folr)

OMY:	110503190(folr)

OGO:	124006342(folr)

ONE:

115142001

OKI:	109909549(folr2)

OKE:	118394795(folr)

OMM:	135546659(folr)

OCLA:

139382938

SALP:

112071326(folr2) 112079423

SNH:	120028906(folr)

CCLU:

121566801 121567817

ELS:	105024055(folr3)

OEP:	134029052(folr)

SFM:	108932358(folr2)

PKI:

111833885

AANG:

118209419(folr)

AROT:

135235814(folr)

CCOG:

133108136(folr)

LOC:	102690865(folr2)

PSPA:

121302728(folr)

ARUT:

117405882 117973036

PSEX:

120523938(folr)

LCM:	102361564(FOLR1)

CMK:	103171823(folr)

RTP:	109926620(folr)

CPLA:

122550965(folr)

HOC:	132816900(folr)

LERI:

129694771 129694772

PMRN:

116942929

LRJ:	133342956 133352019

BFO:	118410131 118411786 118412150 118412152 118417126 118418777 118422830

BBEL:

109466647 109467870 109473455 109480990 109485581

CIN:	100178291 100183675

SCLV:

SPU:

LPIC:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

PFLL:

BTAB:

DCI:	103505516 103505529

CLEC:

106672590

HVI:	124364833 124371911

MQU:	129001213 129004632

PHU:	Phum_PHUM464840

ZNE:

CSEC:

IEL:

HAMR:

FCD:

DPX:	DAPPUDRAFT_299512

DMK:

DPZ:

PVM:

PJA:

PCHN:

PMOO:

PCLA:

123755624 123756621 123760300 123761682 123766120 123768161 138373694

CQD:	128689262 128694525

ESN:

PORN:

HAZT:

PPOI:

ISC:

DSV:

RSAN:

DPTE:

DFR:

CSCU:

CVS:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

LGI:	LOTGIDRAFT_125346 LOTGIDRAFT_218859

PVUL:

PCAN:

LSAX:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

MCAF:

MMER:

123556465 123558557 123561937

RPHI:

132728254

DPOL:

127841640

MAEA:

128227303 128236374 128236387

OBI:

106867890

OSN:

115211818

LJP:

135473983

LAK:	106154473 106154557 106154993 106154995 106154996 106154997 106172479 106172485 106172489 106172490 106172492 106172493 106172494 106175146 106180759 106181659