KEGG ORTHOLOGY: K13740

ORTHOLOGY: K13740

Entry

K13740                      KO

Symbol

sptP

Name

secreted effector protein SptP

Pathway

map05100

Bacterial invasion of epithelial cells

map05132

Salmonella infection

Network

nt06181 Salmonella

Element

N01120

Salmonella SptP to RAC/CDC42-PAK-ERK signaling pathway

Brite

KEGG Orthology (KO) [BR:ko00001]
09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K13740  sptP; secreted effector protein SptP
   05100 Bacterial invasion of epithelial cells
    K13740  sptP; secreted effector protein SptP

Genes

STY:	STY3001(stpA)

STT:	t2780(stpA)

SENT:

TY21A_14045

STM:	STM2878(sptP)

SEO:	STM14_3477(sptP)

SEV:	STMMW_28401

SEY:	SL1344_2858(sptP)

SEM:	STMDT12_C29270

SEJ:	STMUK_2867(sptP)

SEB:	STM474_3017(sptP)

SEF:	UMN798_3126(stpA)

SETU:

STU288_14545

SETC:

CFSAN001921_02685

SENR:

STMDT2_27781(stpA)

SEND:

DT104_28751(stpP)

SENI:

SEEN:

SPT:

SEK:

SPQ:	SPAB_03580

SEI:	SPC_2920(sptP)

SEC:	SCH_2810(sptP)

SEE:	SNSL254_A3083

SENN:

SN31241_39700

SEW:	SeSA_A3031

SEA:	SeAg_B3000

SENS:

Q786_13850

SED:

SeD_A3188

SEG:	SG2781(sptP)

SEL:	SPUL_2875(sptP)

SEGA:

SPUCDC_2861(sptP)

SET:	SEN2720(sptP)

SENA:

SENO:

SENV:

SENQ:

SENL:

SENJ:

SEEC:

SEEB:

SEEP:

SENB:

SENE:

SENC:

SES:	SARI_00095

SBZ:

A464_2902

SBV:	N643_12230

SALZ:

EOS98_05110

» show all

Reference

PMID:19286132

Authors

Humphreys D, Hume PJ, Koronakis V

Title

The Salmonella effector SptP dephosphorylates host AAA+ ATPase VCP to promote development of its intracellular replicative niche.

Journal

Cell Host Microbe 5:225-33 (2009)
DOI:10.1016/j.chom.2009.01.010

Sequence

[stm:STM2878]

Reference

PMID:11163217

Authors

Stebbins CE, Galan JE

Title

Modulation of host signaling by a bacterial mimic: structure of the Salmonella effector SptP bound to Rac1.

Journal

Mol Cell 6:1449-60 (2000)
DOI:10.1016/S1097-2765(00)00141-6

Sequence

[stm:STM2878]

LinkDB

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